Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Pistacia vera
Species name
Pistachio (Pistacia vera) is a species of eudicot in the family Anacardiaceae (sumac family).
Species info
Gene sequence info
Pistacia_vera.4CL.fa
Download
>rna-XM_031430452.1
MEKSGYGRDGIYRSLRPPLVLPKDPNLSMVNFLFRNSSSYESKLALIDADSAQSLTFSQFKSTLIKVSHGFRHLGIKKSDVVLIFAPNSIQYPLCFLGVIAIGGIATTVNPIYTVGELSKQIKDSKPKLLVTVPELWDKVKDFNLPAVILGSKDKLSSNSKIVTFHELVELSGNVLEFPDVSIKQADIATLLYSSGTTGTSKGVILTHRNFIAASLMICMDQDLAGETDNVFLCVLPMFHVFGLSVISYAQLQRGNTLVSMGKFDFVMLLRTIEKYRVTHMWIVPPIVLALAKQSMVKKFDLSSLKQIGCGAAPLGKELMEECAKNFPQALVIQGYGMTETCGIVSVENQRGGVRHSGSAGQLVAGVEAQIVSVDTLKPLPPNHLGNHLGEIWVRGPNMMQGYYNNKQATMLTIDKQGWVHTGDLGYFDGDGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRSPTSSLTEEDVKNFIAKQIAPFKRLRRVTFINTVPKSASGKILRRELIEKVRSKI
>rna-XM_031431033.1
MEKSGYGRDGIYRSLRPRLVLPKDPNLSMVYFLFQNSSSYQSKLALIEADSGESLTFSQFKSTLIRVSHGFCHLGIGKNDIVLIYSPNSIQFPICFLGVIALGAIATTVNPVYTVNELSKQVKDSNPKLVITVPELWDKVKGFNLPAVILGSKENLSSNSKIVTFQDLIELSGNVSEFPDVSIKQTDIAALLYSSGTTGTSKGVILTHRNFIAASLAINMDQDLAGEKDDVYLCVPMFHVFGLAVVLYTQLKKGNTLVSMRKFGFEMLLRTVEKYRVTNMWIVPPIVLALAKQSLVKKFELSSLKLIGSGAAPLGKELMEECAKNFPHAVIIQGYGMTETSGIVSVENPYVAGVRHSGSAGTLAAGIESQIVSVDTLKRLPPNQLGEIWVRGPNVMQGYFNNEEATTLTIDEKGWLHTGDIGYFDWDGRLYVVDRIKELIKYKGFQVAPAELEALIVSHPKILDAVVIPFPDAEAGEVPIAYVVRSPDASLTEEIVKNFVANQVAPFKRLRRVTFINNVPKSASGKILRRELIEKVRSKM
>rna-XM_031416862.1
MEKLKLHSEHNEEIIFRSKYPGVAVPDNLTLPDFVLQDAELYADKVAFVEAMSGKAYTYGDVVRDIKRFAKALKSLGLRKGRVVIVVLPNVAEYGIVALGIMSAGGVFSGANPTAHISELEKQVEAADAKLIVTNGTVYEKVKGLGLPVIVVDEKRIESAINWSELLEAADRAGNYITKEDVQQTDLCALPFSSGTTGMSKGVMLTHRNLVANLCSTLFSVGPEIIGQVTTLGLIPFFHIYGITGICCATLRNKGKVVMMNRFDLRTFLNALITQEITFAPIVPPIILTLVKDPIVEEFDLTKLKLRAVMTAAAPLAPELLNAFEKKFPGVQVQEAYGLTEHSCITLSHGDPVKGHGIAKKNSVGFILPNLEVKFIDPDTGRSLPKNTPGEICVRSLCVMQGYYNNEEETSRTIDKNGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVDDAAVVPLPDEEAGEIPAACVVMNANSKETEEDIMNHVASTVAHYKKVRVLQFVDAIPKSPSGKIMRRLLKEKMVEKMKTKVKKITN
>rna-XM_031392722.1
MISIANSLEQVQKPELSPSTNSNNNEKTHVFKSKLPDIPINNHLPLHTYCFENLSTFADNPCLIAGSTGKSYSFAETHLICRRTAAGLAGLGIKKGDVIMILLQNCAEFVFSFMGASMIGAVTTTANPFYTSPEIFKQFKGSQAKIIITQSQYVDKLRDSNEKFPEIGEDFTVITVDDPPENCLHFSALSEANENQIPQVSIDPDDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLFLKGDDVVLCVLPLFHIYSLNSVLLCSLRAGSAVLLMQKFEIRALLELIQKHKVSVAAVVPPLVLALAKNPMVAEFDLSSIRVVLSGAAPLGKELEGALRSRVPQAILGQGYGMTEAGPVLSMCLAFAKQPFPTKSGSCGTVVRNADLKVIDPDSGSPLPRNQPGEICIRGSQIMQGYLNDPEATATTIDIEGWLHTGDIGFVDDDDEIFIVDRVKEIIKFKGFQVPPAELEALLINHSCIADAAVVPQKDEVAGEVPVAFVVRTKGLELSEEAVKEYVANQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLATPPSSLP
>rna-XM_031401434.1
MEPKQQLQQEDDFIFRSKLPDIYIPNHLPLHSYCFENISEFRDRPCIINGSTGESFSYAEVELTARKVGAGLAKFGINQGDVIMLLLQNCSEFVYAFLGASYIGAISTTANPFYTPAEIAKQSVASKTKLIITQTVYAAKVRDFAEENGVKIITIDSPPDKKWSHFSELTQADESEIPAVKINSDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHKEDVIFCVLPLFHIYSLNSVLLCGLRVGAAILMMQKFEIISLAELVQKHKVTIAPFVPPIVLAIAKSPDVGKYDFSSIRTVLSGAAPMGKELEDAVRAKIPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGISLPRNQSGEICIRGAQIMKGYLNDPEATERTIDKEGWLHTGDTGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVPMKDEAAGEVPVAFIVRSNGSKITEEEIKQYISKQVVFYKRINRVFFSDSIPKAPSGKILRKDLRAKLAAGVPN
>rna-XM_031402012.1
MEVQAKPQEELIVYRSKLPDIYIPNHLPLHSYCFEKIAEVASRPCLINGSTGDVYTYSDVELTSRKIASGLNKLGIQQYDVIMLLLPNFPEFILSFLGASYRGAVATAANPFFTPAEISKQAEASNAKLIITQACYVDKVKALSEKGDVKIMCIDAAPDGCLHFSELTQADENDFPEVKFNPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHCEDVILCVLPLFHIYALNSIFLAGLRAGATILLMQKFEINSLLQLVQRYKVTVAPIVPPIVLAIAKSPDVDKYDLSSIRIIKSGAAPLGKELEDSVRAKFPNATLGQGYGMTEAGPVLAMGLAFAKQPFPIKPGACGTVVRNAEMKIIDPDTGTYLPRNQPGEICIRGDQIMKGYLNDVEATKRTIDSGGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLLTHPRISDAAVVPMKDDQAGEVPVAFIVKANDSQITEDEVKQFISKQVVFYKRINRVFFIDAIPKAPSGKILRKDLRAKLATGLPN
MEKSGYGRDGIYRSLRPPLVLPKDPNLSMVNFLFRNSSSYESKLALIDADSAQSLTFSQFKSTLIKVSHGFRHLGIKKSDVVLIFAPNSIQYPLCFLGVIAIGGIATTVNPIYTVGELSKQIKDSKPKLLVTVPELWDKVKDFNLPAVILGSKDKLSSNSKIVTFHELVELSGNVLEFPDVSIKQADIATLLYSSGTTGTSKGVILTHRNFIAASLMICMDQDLAGETDNVFLCVLPMFHVFGLSVISYAQLQRGNTLVSMGKFDFVMLLRTIEKYRVTHMWIVPPIVLALAKQSMVKKFDLSSLKQIGCGAAPLGKELMEECAKNFPQALVIQGYGMTETCGIVSVENQRGGVRHSGSAGQLVAGVEAQIVSVDTLKPLPPNHLGNHLGEIWVRGPNMMQGYYNNKQATMLTIDKQGWVHTGDLGYFDGDGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRSPTSSLTEEDVKNFIAKQIAPFKRLRRVTFINTVPKSASGKILRRELIEKVRSKI
>rna-XM_031431033.1
MEKSGYGRDGIYRSLRPRLVLPKDPNLSMVYFLFQNSSSYQSKLALIEADSGESLTFSQFKSTLIRVSHGFCHLGIGKNDIVLIYSPNSIQFPICFLGVIALGAIATTVNPVYTVNELSKQVKDSNPKLVITVPELWDKVKGFNLPAVILGSKENLSSNSKIVTFQDLIELSGNVSEFPDVSIKQTDIAALLYSSGTTGTSKGVILTHRNFIAASLAINMDQDLAGEKDDVYLCVPMFHVFGLAVVLYTQLKKGNTLVSMRKFGFEMLLRTVEKYRVTNMWIVPPIVLALAKQSLVKKFELSSLKLIGSGAAPLGKELMEECAKNFPHAVIIQGYGMTETSGIVSVENPYVAGVRHSGSAGTLAAGIESQIVSVDTLKRLPPNQLGEIWVRGPNVMQGYFNNEEATTLTIDEKGWLHTGDIGYFDWDGRLYVVDRIKELIKYKGFQVAPAELEALIVSHPKILDAVVIPFPDAEAGEVPIAYVVRSPDASLTEEIVKNFVANQVAPFKRLRRVTFINNVPKSASGKILRRELIEKVRSKM
>rna-XM_031416862.1
MEKLKLHSEHNEEIIFRSKYPGVAVPDNLTLPDFVLQDAELYADKVAFVEAMSGKAYTYGDVVRDIKRFAKALKSLGLRKGRVVIVVLPNVAEYGIVALGIMSAGGVFSGANPTAHISELEKQVEAADAKLIVTNGTVYEKVKGLGLPVIVVDEKRIESAINWSELLEAADRAGNYITKEDVQQTDLCALPFSSGTTGMSKGVMLTHRNLVANLCSTLFSVGPEIIGQVTTLGLIPFFHIYGITGICCATLRNKGKVVMMNRFDLRTFLNALITQEITFAPIVPPIILTLVKDPIVEEFDLTKLKLRAVMTAAAPLAPELLNAFEKKFPGVQVQEAYGLTEHSCITLSHGDPVKGHGIAKKNSVGFILPNLEVKFIDPDTGRSLPKNTPGEICVRSLCVMQGYYNNEEETSRTIDKNGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVDDAAVVPLPDEEAGEIPAACVVMNANSKETEEDIMNHVASTVAHYKKVRVLQFVDAIPKSPSGKIMRRLLKEKMVEKMKTKVKKITN
>rna-XM_031392722.1
MISIANSLEQVQKPELSPSTNSNNNEKTHVFKSKLPDIPINNHLPLHTYCFENLSTFADNPCLIAGSTGKSYSFAETHLICRRTAAGLAGLGIKKGDVIMILLQNCAEFVFSFMGASMIGAVTTTANPFYTSPEIFKQFKGSQAKIIITQSQYVDKLRDSNEKFPEIGEDFTVITVDDPPENCLHFSALSEANENQIPQVSIDPDDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLFLKGDDVVLCVLPLFHIYSLNSVLLCSLRAGSAVLLMQKFEIRALLELIQKHKVSVAAVVPPLVLALAKNPMVAEFDLSSIRVVLSGAAPLGKELEGALRSRVPQAILGQGYGMTEAGPVLSMCLAFAKQPFPTKSGSCGTVVRNADLKVIDPDSGSPLPRNQPGEICIRGSQIMQGYLNDPEATATTIDIEGWLHTGDIGFVDDDDEIFIVDRVKEIIKFKGFQVPPAELEALLINHSCIADAAVVPQKDEVAGEVPVAFVVRTKGLELSEEAVKEYVANQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLATPPSSLP
>rna-XM_031401434.1
MEPKQQLQQEDDFIFRSKLPDIYIPNHLPLHSYCFENISEFRDRPCIINGSTGESFSYAEVELTARKVGAGLAKFGINQGDVIMLLLQNCSEFVYAFLGASYIGAISTTANPFYTPAEIAKQSVASKTKLIITQTVYAAKVRDFAEENGVKIITIDSPPDKKWSHFSELTQADESEIPAVKINSDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHKEDVIFCVLPLFHIYSLNSVLLCGLRVGAAILMMQKFEIISLAELVQKHKVTIAPFVPPIVLAIAKSPDVGKYDFSSIRTVLSGAAPMGKELEDAVRAKIPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGISLPRNQSGEICIRGAQIMKGYLNDPEATERTIDKEGWLHTGDTGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVPMKDEAAGEVPVAFIVRSNGSKITEEEIKQYISKQVVFYKRINRVFFSDSIPKAPSGKILRKDLRAKLAAGVPN
>rna-XM_031402012.1
MEVQAKPQEELIVYRSKLPDIYIPNHLPLHSYCFEKIAEVASRPCLINGSTGDVYTYSDVELTSRKIASGLNKLGIQQYDVIMLLLPNFPEFILSFLGASYRGAVATAANPFFTPAEISKQAEASNAKLIITQACYVDKVKALSEKGDVKIMCIDAAPDGCLHFSELTQADENDFPEVKFNPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHCEDVILCVLPLFHIYALNSIFLAGLRAGATILLMQKFEINSLLQLVQRYKVTVAPIVPPIVLAIAKSPDVDKYDLSSIRIIKSGAAPLGKELEDSVRAKFPNATLGQGYGMTEAGPVLAMGLAFAKQPFPIKPGACGTVVRNAEMKIIDPDTGTYLPRNQPGEICIRGDQIMKGYLNDVEATKRTIDSGGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLLTHPRISDAAVVPMKDDQAGEVPVAFIVKANDSQITEDEVKQFISKQVVFYKRINRVFFIDAIPKAPSGKILRKDLRAKLATGLPN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University