Enzyme
The enzyme participates in the flavonoid biosynthesis pathway found in plants. It catalyses the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins. While the enzyme from the legume Medicago truncatula (MtANR) can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana (AtANR) uses only NADPH. Also, while the substrate preference of MtANR is cyanidin>pelargonidin>delphinidin, the reverse preference is found with AtANR. cf. EC 1.3.1.112, anthocyanidin reductase [(2S)-flavan-3-ol-forming].
ANR
Enzyme
Anthocyanidin reductase
Enzyme name
EC:1.3.1.77
Entry
Oxidoreductases;Acting on the CH-CH group of donors;With NAD+ or NADP+ as acceptor
Class
(2R,3R)-flavan-3-ol:NAD(P)+ 3,4-oxidoreductase
Sysname
a (2R,3R)-flavan-3-ol + 2 NAD(P)+ = an anthocyanidin with a 3-hydroxy group + 2 NAD(P)H + H+ [RN:R07351 R07352]
Reaction
anthocyanidin with a 3-hydroxy group [CPD:C21381];NADH [CPD:C00004];NADPH [CPD:C00005];H+ [CPD:C00080]
Product
Species information
Phyllostachys edulis
Species name
Kikko-chiku (Phyllostachys edulis) is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Phyllostachys_edulis.ANR.fa
Download
>PH02Gene16551.t1
MSRACVTGAAGYIAVWLIKKLLERGCVVHATLRDLGDEKKTELLRGLPGAAERLELFEADIYDAATFEPAISGCEFVFLVATPLVHNPGSTKYKNITEAIVDATRIILKQCERSKTVRRVIHTASVVAASPLKGDGDGYKDFMDESCWTPLNLSYGYSNIHLDAYVSSKSLSEKELLRYNESGDRAFEVVTLACALVGGDTIQPNLWSSIPVIVAPLTGHEVHHNSLKFLQALLGSVPLAHIEDVCEAHVFCMEQPSIAGRFLCAAGYPNMKDYVDRFAAKYPEHKILLKEVVGEEARMQADTNKLVDLGFKYKYGVEETLDCSVECAKRMGEL
>PH02Gene48988.t1
MSRACVTGAAGNIATWLIKKLLERGCVVHATLRDLGDEKKTELLRGLPGAAERLELFEADIYDAATFEPAISGCEFVFLVATPLMHNAGSTKYKNITEAIVDATRIILKQCERSKTVRRVIHTASVVAASPLKGDGDGYKDFMDESCWTPLNLSYGYSNIHMDAYVSSKSLSEKELLRYNESGDRAFEVVTLACALVGGDTIQPYLWSSIPVIVAPLTGHEVHHNSLKFLQALLGSVPLAHIEDVCEAHVFCMEQPSIAGRFLCAAGYPNMKDYVDRFAAKYPEHKILLKEVVGEGVRVQADTNKLVDLGFKYKYGVEETLDCSVERAKRMGEL
>PH02Gene37963.t1
MAEEGESSRSSGGIRVCVTGGAGFIGSWLVKKLLGKGYTVHATLRSIGDEKKAGLLRRLVPGAAPERLQLFEADLYDATTFAPAIAGCQFVFLIATPFQHDSASSKYKNTAEAAVDAVRVILRQCAESKTVKRVIHTASITTASPLKEVSGAGYKDFISESCWTPVDVDYPLRSAHFDKYILSKLLSEKELLSYNDCENPAFEVVTLSCGLVAGDTVLGHVPETLESTVSPVARDEPHFMLPSLLQRLLGSVPLVHVDDVCEALVFCMEQPSVSGRFLCSAAYPTITDIVDHYANKYPHLDLLKETDEVARVQPDRNKLGELGFRYKYGLEEILDGSVECAVRLGCLDASKLGVQKA
>PH02Gene37964.t1
MPTRPTHGCSSKGCLLKAELLKPHGVWAYGDGRRLAGGLAGEGGVRVYLSGRPGAAAPVCPGVVPSLLPRIRAGFHVTSAKSEERPPLLYGAAHIGWMSKSIPVEELAKEEGKSSGGVGVCVTGGAGFIGSWLVKKLLERGYTVHSTLRSINDERKAGFLRRLVPGAAEYVQSKLMSEELLLSYNDGESPAFEVVTLLCPVVAGGTLQSDVPSSLECSVSPVSRDGRKLEVMRQLQALIVSVPLAHVDDVCDALVFCMERPSMAGQFLCSAV
>PH02Gene50666.t1
MEEERKSGGVVRVCVTGGAGFIGSWLVKKLLDKGYTVHATLRSIGDEKKEGLLRRLVPGAAAERLQLFEADLYDAATFAPAIAGCQFVFLVATPYGQEAASSKYKNTAEAAVDAVRVILRQCAESKTVKRVIHTASISAASPLKEISGAGYKDFINESCWTPLDVDYPLRIAHFDVSVPFLQTEVRSQLLIQNGNLATYKFMTTCDVLVDEYLLVTL
>PH02Gene25610.t1
MERPLVSGRFLCCAAYPTITDIVDHYANKYPHLDLLKEEAILHLNKLGELGFRYKYGVEEILDDDVECAVRLGCLDVSKLGVQRA
>PH02Gene27994.t1
MEEEGKSGGGGGVRVCVTGGAGFIGSWLVKKLLDKGYTVHATLRSIGDEKKAGLLRRLVRGAAAERLQLFEADLYDAATFAPAIAGCQFVFLVATPYGQEAASSKYKNTAEAAVDAVRVILRQCAESKTVKRVIHTASISTASPLKEISGAGYKDFINESCWTSLDVDYPLRSAYFDKYILSKLLSEKELLSYNDGENPAFEVVTLPCSLVAGDTVLGHVPETLVSAVSPVARDELRFGFLRLVQRLLGSMPLVHVDDVCDALVFCMERPSISGRFLCSAAYPTIHDIVDHYASKYPHLDLFKETEEVARVQPDRNKLGELGFRYKYGMEEILDASVECAVRLGCLDASKLSVQKG
>PH02Gene20359.t2
MSRVCVTGAAGYIATWLVKKLLGRGCVVHATLRDLGDEKKTELLRGLPGAAERLELFEADIYDAATFEPAISSCEFVFLVATPPMHDPGSAKYKNTTEAIVDATRIILQQCERSKTVRRVIHTASVTAASPLKEDGDGYKDFTNESCWTPLNLSYGYSNIHLDAYVSSKSLSEKELLSYNESKDRAFEVVTLACALVGGDTVQPYLSISLQAVVAPLTGHGVHHNSLKFMQTLLGSVPLAHIEDICEAHVFCMERPSIAGRFLCAAGYPNMQDYVDRFAAKYPEHKVLLKEVVGEGVRVQADTNKLVDLGFKYKYGVEETLDCSVECAKRLGEL
>PH02Gene25166.t1
MELHGVLRKSPCDVGIWYAIAKTLAEKAAWEFAKENSIDLVTVLPTFVVGHNLSPELGPTASNVLGLLHGETEKFTMFTSTMSRAATSWSMKLPVPKGGTYATRRFLITTSWSPCLQNDSRHIPSRRVSRTFTASRMIRELGLKFKGVEEMFDDSVESLKAHGYLLKRAA
>PH02Gene24052.t1
MSAVERKTACVTGGNGYIASALIKMLLEKGYAVKTTVRNPDDMEKNSHLKDLQALGPLKVLRADLDEEGSFDEAVAGCDYAFLVAAPVNLQSENPEKEVIEAAVGGTLNVMRSCVKAGTVKRVILTSSAAAVTSRPLQGDGHVLDEESWSDVEYLTANKKSPAWAYAVSKVLLEKEACKFAQENNISLVTVCPVISVGVAPAPKVNTSVPGCLSFLSGDETLIDTLKRVEKASGSTPMVHVDDLCRAEVFVAEEESASGRYICCSLDTTVVELARFLAAKYPQYNVKTDGFGDLPEKPRVCLSSEKLIRDGFEFKYKTLDEIYDDVVQYGKALGILPY
>PH02Gene24053.t1
MVHVDNLCRAEVFVAEESASGRYICCSLDTTIGELAHFLAAKYPQYNVKANGVCLSSEKLIRDGFEFKYKTLDEIYDDVVQYGKALGILPLLMFLCL
>PH02Gene19887.t1
MSEGGRKTACVTGGNGYIASALIKMLLEKGYAMTWGRTPTSRTSEHLAPLKVLWADLDVEGSFDEAVAGCDYAFLVAAPVNFVSENPEKEVIEPAVRGTLNVMRSCVKAGTVKRVILTSSVAAASRRPLQSDGHVLNEESWSDVEYLRTEKPLAWGYAVSKVLLEKEACKFAQENDISLVTVCPVVIVGAAPAPKAQTSIPLSLSLLSGDEALINGLKSMEKDTGTVPMAHVDDLCRAEMFVAEKESASGRYICCSLNTTVVELARFLAEKYPQSNVKTNWYEFFGDLPKNPRVYISSEKLVKEGFEFKYKTLGDIYDDVVEYGMALGILPC
>PH02Gene28873.t1
MTLSRAATVWFCLVVVRRRISPSERLQLFEADLYDATTFAPAIAGCQFVFLIATPFQHDSASSKYKNTAKAAADAVRVILRQCADSKMVKRVTVNLNVARVQPDRNKLGELGFRYKYGVEEILDDDVECAVRLGCLDASKLGVKL
>PH02Gene32095.t1
MSAGERKTACVTGGNGYIASALIKMLLENGYAVKTTVRNPDDMEKNSHLKNLQALGPLEILRADLDEQGSFDEAVAGCDYAFLVAAPVNVESENPEKELIEAGVQGTLNVMRSCVKAGTVKRVILTSSAAAISGQPLLGDGHVLDEESWSDVEYLRTEKPPVWAYSVSKVLLEKEACKFAQVNNISLVTVCPVVTVGVAPAPIVKTSVPACLSFLSGDEARIDILKSLEKATGSIPMVHVDDLCRAEMFAAEEESVSGRP
>PH02Gene32096.t1
MSAVERKTACVTGGNGYIASALIKMLLEKGYAVKTTVRNPDDMEKISHLKDLQALGPLKAENPEREMIEPAVRGTLNVMRSSVKAGTVKRVILTSSSAAVSSRPLQGGGHVLDEESWSDVEYLRTEKPPLWGYAVSKVLLEKEACKFAQENNISLVTVFPVFTLGEAPVSKAKTSVPIILSLLSGDETQLNLLKDLQAVSGIVPIVHIDDLCRAELFVAENESSSGRYICCSHNSTILQLARLLAEKYPQYNVKTDCFGDYPEKPRVSVSSEKLVREGFEFKYKNLDEIFDDVVKYGKALGILPY
>PH02Gene32097.t1
MLAVETKTACVTGGNGYIASALIKMLLEKGYAVKTTVRNPDDMEKNSHLKDLQALGPLKVLRADLDEEGSFDEAVAGCDYAFLVAAPVNLKSENPEREVIEPAVRGTLNVMRSCMKAGTVKRVILTSSAAAVSSRPLQGGGHVLDEESWSDVEYLRTKKSPAWAYPVSKVLLEKEACKFAQVNNISLVTVCPVVTVGVAPAPMVNTSVPACLSLLSGDEATIDTLKSIEKASGSIPMVHVDDLCRAEMFAAEEESVSGRYICCSLNTTVVELARFLAGKYPQYNVKTTCFGDLPEKPRVCLSSEKLVQDGFEFKYKTLDEIYDDDVVEYGKALGILPF
>PH02Gene46020.t1
MSAGERKMACVTGGNGYIASILIKMLLEKGYAVKTTVRNPGDEAQLDLLKGLHAVSGSVSIVHIDDLCGAELFVAENESSSGRYICCSHNTTILQLARLLAEKYPQYNVKTDCFGDYPEKPRVCLSSEKLVREGFEFKYKNLDEIFDDVVEYGKALGILAN
>PH02Gene46022.t1
MSAGERKTACVTGGNGYIASALIKMLLENGYAVKTTVRNPDDMEKNSHLKNLQALGPLEILRADLDEQGCFDEAVAGCDYAFLVAAPVNVESENPEKELIEAGVQGTLNVMRSCVKAGTVKRVILTSSVAAISRRPLQGDGHVLDEDSWSDVEYLRTENPPTWGYAVSKVLLEKEACKFAQENNISLVTVFPVVTLGAAPVSKAKTSVPVTLSLLSGDETQLNLLKGLQAVSGTVSIVHIDDLCCAELFVAENESSSGRYICCSHNTTILQLARLLAEKYPQYNVKTDCFGDYPEKPRVCVSSEKLVREGFEFKYKNLDEIFDDVVKYGKALGILPY
MSRACVTGAAGYIAVWLIKKLLERGCVVHATLRDLGDEKKTELLRGLPGAAERLELFEADIYDAATFEPAISGCEFVFLVATPLVHNPGSTKYKNITEAIVDATRIILKQCERSKTVRRVIHTASVVAASPLKGDGDGYKDFMDESCWTPLNLSYGYSNIHLDAYVSSKSLSEKELLRYNESGDRAFEVVTLACALVGGDTIQPNLWSSIPVIVAPLTGHEVHHNSLKFLQALLGSVPLAHIEDVCEAHVFCMEQPSIAGRFLCAAGYPNMKDYVDRFAAKYPEHKILLKEVVGEEARMQADTNKLVDLGFKYKYGVEETLDCSVECAKRMGEL
>PH02Gene48988.t1
MSRACVTGAAGNIATWLIKKLLERGCVVHATLRDLGDEKKTELLRGLPGAAERLELFEADIYDAATFEPAISGCEFVFLVATPLMHNAGSTKYKNITEAIVDATRIILKQCERSKTVRRVIHTASVVAASPLKGDGDGYKDFMDESCWTPLNLSYGYSNIHMDAYVSSKSLSEKELLRYNESGDRAFEVVTLACALVGGDTIQPYLWSSIPVIVAPLTGHEVHHNSLKFLQALLGSVPLAHIEDVCEAHVFCMEQPSIAGRFLCAAGYPNMKDYVDRFAAKYPEHKILLKEVVGEGVRVQADTNKLVDLGFKYKYGVEETLDCSVERAKRMGEL
>PH02Gene37963.t1
MAEEGESSRSSGGIRVCVTGGAGFIGSWLVKKLLGKGYTVHATLRSIGDEKKAGLLRRLVPGAAPERLQLFEADLYDATTFAPAIAGCQFVFLIATPFQHDSASSKYKNTAEAAVDAVRVILRQCAESKTVKRVIHTASITTASPLKEVSGAGYKDFISESCWTPVDVDYPLRSAHFDKYILSKLLSEKELLSYNDCENPAFEVVTLSCGLVAGDTVLGHVPETLESTVSPVARDEPHFMLPSLLQRLLGSVPLVHVDDVCEALVFCMEQPSVSGRFLCSAAYPTITDIVDHYANKYPHLDLLKETDEVARVQPDRNKLGELGFRYKYGLEEILDGSVECAVRLGCLDASKLGVQKA
>PH02Gene37964.t1
MPTRPTHGCSSKGCLLKAELLKPHGVWAYGDGRRLAGGLAGEGGVRVYLSGRPGAAAPVCPGVVPSLLPRIRAGFHVTSAKSEERPPLLYGAAHIGWMSKSIPVEELAKEEGKSSGGVGVCVTGGAGFIGSWLVKKLLERGYTVHSTLRSINDERKAGFLRRLVPGAAEYVQSKLMSEELLLSYNDGESPAFEVVTLLCPVVAGGTLQSDVPSSLECSVSPVSRDGRKLEVMRQLQALIVSVPLAHVDDVCDALVFCMERPSMAGQFLCSAV
>PH02Gene50666.t1
MEEERKSGGVVRVCVTGGAGFIGSWLVKKLLDKGYTVHATLRSIGDEKKEGLLRRLVPGAAAERLQLFEADLYDAATFAPAIAGCQFVFLVATPYGQEAASSKYKNTAEAAVDAVRVILRQCAESKTVKRVIHTASISAASPLKEISGAGYKDFINESCWTPLDVDYPLRIAHFDVSVPFLQTEVRSQLLIQNGNLATYKFMTTCDVLVDEYLLVTL
>PH02Gene25610.t1
MERPLVSGRFLCCAAYPTITDIVDHYANKYPHLDLLKEEAILHLNKLGELGFRYKYGVEEILDDDVECAVRLGCLDVSKLGVQRA
>PH02Gene27994.t1
MEEEGKSGGGGGVRVCVTGGAGFIGSWLVKKLLDKGYTVHATLRSIGDEKKAGLLRRLVRGAAAERLQLFEADLYDAATFAPAIAGCQFVFLVATPYGQEAASSKYKNTAEAAVDAVRVILRQCAESKTVKRVIHTASISTASPLKEISGAGYKDFINESCWTSLDVDYPLRSAYFDKYILSKLLSEKELLSYNDGENPAFEVVTLPCSLVAGDTVLGHVPETLVSAVSPVARDELRFGFLRLVQRLLGSMPLVHVDDVCDALVFCMERPSISGRFLCSAAYPTIHDIVDHYASKYPHLDLFKETEEVARVQPDRNKLGELGFRYKYGMEEILDASVECAVRLGCLDASKLSVQKG
>PH02Gene20359.t2
MSRVCVTGAAGYIATWLVKKLLGRGCVVHATLRDLGDEKKTELLRGLPGAAERLELFEADIYDAATFEPAISSCEFVFLVATPPMHDPGSAKYKNTTEAIVDATRIILQQCERSKTVRRVIHTASVTAASPLKEDGDGYKDFTNESCWTPLNLSYGYSNIHLDAYVSSKSLSEKELLSYNESKDRAFEVVTLACALVGGDTVQPYLSISLQAVVAPLTGHGVHHNSLKFMQTLLGSVPLAHIEDICEAHVFCMERPSIAGRFLCAAGYPNMQDYVDRFAAKYPEHKVLLKEVVGEGVRVQADTNKLVDLGFKYKYGVEETLDCSVECAKRLGEL
>PH02Gene25166.t1
MELHGVLRKSPCDVGIWYAIAKTLAEKAAWEFAKENSIDLVTVLPTFVVGHNLSPELGPTASNVLGLLHGETEKFTMFTSTMSRAATSWSMKLPVPKGGTYATRRFLITTSWSPCLQNDSRHIPSRRVSRTFTASRMIRELGLKFKGVEEMFDDSVESLKAHGYLLKRAA
>PH02Gene24052.t1
MSAVERKTACVTGGNGYIASALIKMLLEKGYAVKTTVRNPDDMEKNSHLKDLQALGPLKVLRADLDEEGSFDEAVAGCDYAFLVAAPVNLQSENPEKEVIEAAVGGTLNVMRSCVKAGTVKRVILTSSAAAVTSRPLQGDGHVLDEESWSDVEYLTANKKSPAWAYAVSKVLLEKEACKFAQENNISLVTVCPVISVGVAPAPKVNTSVPGCLSFLSGDETLIDTLKRVEKASGSTPMVHVDDLCRAEVFVAEEESASGRYICCSLDTTVVELARFLAAKYPQYNVKTDGFGDLPEKPRVCLSSEKLIRDGFEFKYKTLDEIYDDVVQYGKALGILPY
>PH02Gene24053.t1
MVHVDNLCRAEVFVAEESASGRYICCSLDTTIGELAHFLAAKYPQYNVKANGVCLSSEKLIRDGFEFKYKTLDEIYDDVVQYGKALGILPLLMFLCL
>PH02Gene19887.t1
MSEGGRKTACVTGGNGYIASALIKMLLEKGYAMTWGRTPTSRTSEHLAPLKVLWADLDVEGSFDEAVAGCDYAFLVAAPVNFVSENPEKEVIEPAVRGTLNVMRSCVKAGTVKRVILTSSVAAASRRPLQSDGHVLNEESWSDVEYLRTEKPLAWGYAVSKVLLEKEACKFAQENDISLVTVCPVVIVGAAPAPKAQTSIPLSLSLLSGDEALINGLKSMEKDTGTVPMAHVDDLCRAEMFVAEKESASGRYICCSLNTTVVELARFLAEKYPQSNVKTNWYEFFGDLPKNPRVYISSEKLVKEGFEFKYKTLGDIYDDVVEYGMALGILPC
>PH02Gene28873.t1
MTLSRAATVWFCLVVVRRRISPSERLQLFEADLYDATTFAPAIAGCQFVFLIATPFQHDSASSKYKNTAKAAADAVRVILRQCADSKMVKRVTVNLNVARVQPDRNKLGELGFRYKYGVEEILDDDVECAVRLGCLDASKLGVKL
>PH02Gene32095.t1
MSAGERKTACVTGGNGYIASALIKMLLENGYAVKTTVRNPDDMEKNSHLKNLQALGPLEILRADLDEQGSFDEAVAGCDYAFLVAAPVNVESENPEKELIEAGVQGTLNVMRSCVKAGTVKRVILTSSAAAISGQPLLGDGHVLDEESWSDVEYLRTEKPPVWAYSVSKVLLEKEACKFAQVNNISLVTVCPVVTVGVAPAPIVKTSVPACLSFLSGDEARIDILKSLEKATGSIPMVHVDDLCRAEMFAAEEESVSGRP
>PH02Gene32096.t1
MSAVERKTACVTGGNGYIASALIKMLLEKGYAVKTTVRNPDDMEKISHLKDLQALGPLKAENPEREMIEPAVRGTLNVMRSSVKAGTVKRVILTSSSAAVSSRPLQGGGHVLDEESWSDVEYLRTEKPPLWGYAVSKVLLEKEACKFAQENNISLVTVFPVFTLGEAPVSKAKTSVPIILSLLSGDETQLNLLKDLQAVSGIVPIVHIDDLCRAELFVAENESSSGRYICCSHNSTILQLARLLAEKYPQYNVKTDCFGDYPEKPRVSVSSEKLVREGFEFKYKNLDEIFDDVVKYGKALGILPY
>PH02Gene32097.t1
MLAVETKTACVTGGNGYIASALIKMLLEKGYAVKTTVRNPDDMEKNSHLKDLQALGPLKVLRADLDEEGSFDEAVAGCDYAFLVAAPVNLKSENPEREVIEPAVRGTLNVMRSCMKAGTVKRVILTSSAAAVSSRPLQGGGHVLDEESWSDVEYLRTKKSPAWAYPVSKVLLEKEACKFAQVNNISLVTVCPVVTVGVAPAPMVNTSVPACLSLLSGDEATIDTLKSIEKASGSIPMVHVDDLCRAEMFAAEEESVSGRYICCSLNTTVVELARFLAGKYPQYNVKTTCFGDLPEKPRVCLSSEKLVQDGFEFKYKTLDEIYDDDVVEYGKALGILPF
>PH02Gene46020.t1
MSAGERKMACVTGGNGYIASILIKMLLEKGYAVKTTVRNPGDEAQLDLLKGLHAVSGSVSIVHIDDLCGAELFVAENESSSGRYICCSHNTTILQLARLLAEKYPQYNVKTDCFGDYPEKPRVCLSSEKLVREGFEFKYKNLDEIFDDVVEYGKALGILAN
>PH02Gene46022.t1
MSAGERKTACVTGGNGYIASALIKMLLENGYAVKTTVRNPDDMEKNSHLKNLQALGPLEILRADLDEQGCFDEAVAGCDYAFLVAAPVNVESENPEKELIEAGVQGTLNVMRSCVKAGTVKRVILTSSVAAISRRPLQGDGHVLDEDSWSDVEYLRTENPPTWGYAVSKVLLEKEACKFAQENNISLVTVFPVVTLGAAPVSKAKTSVPVTLSLLSGDETQLNLLKGLQAVSGTVSIVHIDDLCCAELFVAENESSSGRYICCSHNTTILQLARLLAEKYPQYNVKTDCFGDYPEKPRVCVSSEKLVREGFEFKYKNLDEIFDDVVKYGKALGILPY
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University