Enzyme
A cytochrome P-450 (heme-thiolate) protein found in plants. The enzyme is involved in flavonoid biosynthesis.
C4H
Enzyme
Cinnamate 4-hydroxylase
Enzyme name
EC:1.14.14.91
Entry
Oxidoreductases;Acting on paired donors, with incorporation or reduction of molecular oxygen;With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Class
trans-cinnamate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
Sysname
trans-cinnamate + [reduced NADPH---hemoprotein reductase] + O2 = 4-hydroxycinnamate + [oxidized NADPH---hemoprotein reductase] + H2O[RN:R02253]
Reaction
4-hydroxycinnamate [CPD:C00811];[oxidized NADPH---hemoprotein reductase] [CPD:C03161];H2O [CPD:C00001]
Product
Species information
Phoenix dactylifera
Species name
Date palm (Phoenix dactylifera) is a species of monocot in the family Arecaceae (palm family).
Species info
Gene sequence info
Phoenix_dactylifera.C4H.fa
Download
>rna-XM_008790299.4
MDLALLEKALLGLFASVVVAIAVSKLRGKRLRLPPGPLPVPVFGNWLQVGDDLNHRNLSALARRFGDILLLRMGQRNLVVVSSPSLAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRTGWEDEAARVVADVKADPKAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEEDPLFLRLRALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKEVKERRLQLFKDYFLEERKKLSSTKPADNAELKCAIDHILDAEKKGEINEDNVLYIVENINVAAIETTLWSIEWAIAELVNHPEIQQKLCKELDTVLGPGVQVTEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWLLANNPDHWKKPEEFRPERFLQEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQKQLDTAEKGGQFSLHILKHSTIVAKPRVF
>rna-XM_008784447.4
MDLVLLEKSLLGLFAAVTLAIAVSKLRGKRFRLPPGPLPVPIFGNWLQVGDDLNHRNLTALAKRFGDIFLLRMGQRNLVVVSSPEMARDVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNRHGWEEEARRVVEDVKANPNAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEDDPLFNKLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICQEVKDRRLQLFKDFFIKDRKKLASTKGASNMELKCAIDHILEAERKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPGIQRKLRQELDTVLGPGVQITEPDIPKLPYLQAVVKETLRLRMAIPLLVPHMNLHDAKLAGCDIPAESKILVNAWWLANNPDNWKNPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILNITIGQLVQNFELLPPPGQSKIDTSEKGGQFSLHILKHSTIVCKPRVF
>rna-XM_039124365.1
MDLVLLEKSLLGLFAAVTLAIAVSKLRGKRFRLPPGPLPVPIFGNWLQVGDDLNHRNLTALAKRFGDIFLLRMGQRNLVVVSSPEMARDVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNRHGWEEEARRVVEDVKANPNAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEDDPLFNKLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICQEVKDRRLQLFKDFFIKDRKKLASTKGASNMELKCAIDHILEAERKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQRKLRQELDTVLGPGVQITEPDIPKLPYLQAVVKETLRLRMAIPLLVPHMNLHDAKLAGCDIPAESKILVNAWWLANNPDNWKNPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILNITIGQLVQNFELLPPPGQSKIDTSEKGGQFSLHILKHSTIVCKPRVF
>rna-XM_008784589.4
MAFAPGKLALSILLSLTFDFAAKSLFPIQSSIALSIPFLLFLSLLFSNFKRSNSPPGPLSIPIFGNWLQVGNDLNHRFLANLSQKYGSFFLLKLGARNLVVVSDPKLAAEVLHTQGVEFGSRPRNVVFDIFTGNGQDMVFTVYGDHWRKMRRIMTLPFFTNKVVQQYRGMWEEEMDLVVKDLCGDRIAQEQGMVIRRRLQLMLYNIMYRMMFDARFESAADPLFLEATRFNSERSRLAQSFEYNYGDFIPILRPFLRGYLNKCRDLQSRRLAFFNNYYVEKRRKVMAADGDGHKARCAIDHILEAEKNGEISAENVIYIVENINVAAIETTLWSMEWAIAELANHPAVQEKLRREIADVLEGDAVTESNLQRLPYLQAVVRETLRLHTPIPLLVPHMNLEEAKLGGCTIPEGSKVVVNAWWLANNPAWWDNPEEFRPERFLEEETAVDAVVGGKVDFRFLPFGVGRRSCPGIILALPILGLILGKLVANFEMRPPPGMEKIDVSEKGGQFSLHIAEHSVVAFRPVKK
>rna-XM_008799947.4
MAFSIKTAAISTLVSLGFVFVAKPLLPIQSLVPLSVFLFLASLTLISNSSRPPNTPPGPVSIPIFGNWLQVGNDLNHRFLASMAEKFGSVFLLKLGARNLVVVSDPKLASEVLHTQGVEFGSRPRNVVFDIFTGNGQDMVFTVYGEHWRKMRRIMTLPFFTNKVVQQYKEAWEEEMDAVVEDLRGNKRAQEEGMVIRRRLQLMLYNIMYRMMFDTRFESDSDPLFQQATRFNSERSRLAQSFEYNYGDFIPILRPFLRGYLNKCKDLQSRRLAFFNNNYVEKRREVMATSGDRNKPRCAIDHILEAEKNGEISSENVIYIVENINVAAIETTLWSMEWAIAELVNHPTVQDKVRREIADALGDEPVTETNLHKLPYLQAVVKETLRLHSPIPLLVPHMNLEEAKLGGYTIPSGSKVVVNAWWLANNPEWWYRPEEFRPERFLKEEMEVDAVVGGKVDFRFLPFGVGRRSCPGIILALPILGLVVGKLVRNFELVPPPGVDKVDVSEKGGQFSLHIATHSVIAFRPIAA
>rna-XM_008794027.3
MDLVLLEKALLGLFAAIVVAIAVSKLRGKRFRLPPGPLPVPVFGNWLQVGDDLNHRNLSALARRFGDILLLRMGQRNLVVVSSPAVARDVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRTGWEDEAARVVADVKADPKAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEEDPLFLRLKALNGERSRLAQSFEYNYGDFIPLLRPFLRGYLKICKEVKERRLQLFKDYFLEERKKLASTKPVDNAGLKCAIDHILDAEKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPDVQQKLRNELDTVLGPGVAVTEPDTQKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGFDIPAESKILVNAWWLANNPDHWKKPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQKKLDTSEKGGQFSLHILKHSTIVAKPRMI
>rna-XM_008812616.4
MDLVLVEKALLGLFAAVTIAIAVSKLRGKRFKLPPGPLPVPIFGNWLQVGDDLNHRNLTALAKRFGDIFLLRMGQRNLVVVSSPELAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNRHGWEEEARRVVEDVMANPKAATEGIVLRRRLQLMMYNNMFRIMFDRRFESEDDPLFNKLRALNGERSRLAQSFEYNYGDFIPILRPFLKGYLKICQEVKDRRLQLFKTYFIDERKKLASTKGATNVELKCAIDHILEAERKGEINEDNVLYIVENINVAAIETTQWSIEWGIAELVNHPEIQRKLRRELDTVLGPGVQITEPDTQKLPYLQAVIKETLRRRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLANNPDNWKNPDEFRPERFLAEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKIDTAEKGGQFSLHILKHSTIVCKPRLV
>rna-XM_039133961.1
MDLVLLEKALLGLFAAVTLAIAASKLPGKRFGDDLNHRNRTALAKRFGDIFVLRMGQWNLVVVSSLEMARDVLHTQGVEFGSRTCNVVFDIFTGKGQDMVFTIYGEHWRKVCRIMTVPFFTNKVVQQNRHGWEEEARRVVEDVKAIPNAATELGGHFWRRRWWG
MDLALLEKALLGLFASVVVAIAVSKLRGKRLRLPPGPLPVPVFGNWLQVGDDLNHRNLSALARRFGDILLLRMGQRNLVVVSSPSLAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRTGWEDEAARVVADVKADPKAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEEDPLFLRLRALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKEVKERRLQLFKDYFLEERKKLSSTKPADNAELKCAIDHILDAEKKGEINEDNVLYIVENINVAAIETTLWSIEWAIAELVNHPEIQQKLCKELDTVLGPGVQVTEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWLLANNPDHWKKPEEFRPERFLQEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQKQLDTAEKGGQFSLHILKHSTIVAKPRVF
>rna-XM_008784447.4
MDLVLLEKSLLGLFAAVTLAIAVSKLRGKRFRLPPGPLPVPIFGNWLQVGDDLNHRNLTALAKRFGDIFLLRMGQRNLVVVSSPEMARDVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNRHGWEEEARRVVEDVKANPNAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEDDPLFNKLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICQEVKDRRLQLFKDFFIKDRKKLASTKGASNMELKCAIDHILEAERKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPGIQRKLRQELDTVLGPGVQITEPDIPKLPYLQAVVKETLRLRMAIPLLVPHMNLHDAKLAGCDIPAESKILVNAWWLANNPDNWKNPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILNITIGQLVQNFELLPPPGQSKIDTSEKGGQFSLHILKHSTIVCKPRVF
>rna-XM_039124365.1
MDLVLLEKSLLGLFAAVTLAIAVSKLRGKRFRLPPGPLPVPIFGNWLQVGDDLNHRNLTALAKRFGDIFLLRMGQRNLVVVSSPEMARDVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNRHGWEEEARRVVEDVKANPNAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEDDPLFNKLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICQEVKDRRLQLFKDFFIKDRKKLASTKGASNMELKCAIDHILEAERKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQRKLRQELDTVLGPGVQITEPDIPKLPYLQAVVKETLRLRMAIPLLVPHMNLHDAKLAGCDIPAESKILVNAWWLANNPDNWKNPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILNITIGQLVQNFELLPPPGQSKIDTSEKGGQFSLHILKHSTIVCKPRVF
>rna-XM_008784589.4
MAFAPGKLALSILLSLTFDFAAKSLFPIQSSIALSIPFLLFLSLLFSNFKRSNSPPGPLSIPIFGNWLQVGNDLNHRFLANLSQKYGSFFLLKLGARNLVVVSDPKLAAEVLHTQGVEFGSRPRNVVFDIFTGNGQDMVFTVYGDHWRKMRRIMTLPFFTNKVVQQYRGMWEEEMDLVVKDLCGDRIAQEQGMVIRRRLQLMLYNIMYRMMFDARFESAADPLFLEATRFNSERSRLAQSFEYNYGDFIPILRPFLRGYLNKCRDLQSRRLAFFNNYYVEKRRKVMAADGDGHKARCAIDHILEAEKNGEISAENVIYIVENINVAAIETTLWSMEWAIAELANHPAVQEKLRREIADVLEGDAVTESNLQRLPYLQAVVRETLRLHTPIPLLVPHMNLEEAKLGGCTIPEGSKVVVNAWWLANNPAWWDNPEEFRPERFLEEETAVDAVVGGKVDFRFLPFGVGRRSCPGIILALPILGLILGKLVANFEMRPPPGMEKIDVSEKGGQFSLHIAEHSVVAFRPVKK
>rna-XM_008799947.4
MAFSIKTAAISTLVSLGFVFVAKPLLPIQSLVPLSVFLFLASLTLISNSSRPPNTPPGPVSIPIFGNWLQVGNDLNHRFLASMAEKFGSVFLLKLGARNLVVVSDPKLASEVLHTQGVEFGSRPRNVVFDIFTGNGQDMVFTVYGEHWRKMRRIMTLPFFTNKVVQQYKEAWEEEMDAVVEDLRGNKRAQEEGMVIRRRLQLMLYNIMYRMMFDTRFESDSDPLFQQATRFNSERSRLAQSFEYNYGDFIPILRPFLRGYLNKCKDLQSRRLAFFNNNYVEKRREVMATSGDRNKPRCAIDHILEAEKNGEISSENVIYIVENINVAAIETTLWSMEWAIAELVNHPTVQDKVRREIADALGDEPVTETNLHKLPYLQAVVKETLRLHSPIPLLVPHMNLEEAKLGGYTIPSGSKVVVNAWWLANNPEWWYRPEEFRPERFLKEEMEVDAVVGGKVDFRFLPFGVGRRSCPGIILALPILGLVVGKLVRNFELVPPPGVDKVDVSEKGGQFSLHIATHSVIAFRPIAA
>rna-XM_008794027.3
MDLVLLEKALLGLFAAIVVAIAVSKLRGKRFRLPPGPLPVPVFGNWLQVGDDLNHRNLSALARRFGDILLLRMGQRNLVVVSSPAVARDVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRTGWEDEAARVVADVKADPKAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEEDPLFLRLKALNGERSRLAQSFEYNYGDFIPLLRPFLRGYLKICKEVKERRLQLFKDYFLEERKKLASTKPVDNAGLKCAIDHILDAEKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPDVQQKLRNELDTVLGPGVAVTEPDTQKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGFDIPAESKILVNAWWLANNPDHWKKPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQKKLDTSEKGGQFSLHILKHSTIVAKPRMI
>rna-XM_008812616.4
MDLVLVEKALLGLFAAVTIAIAVSKLRGKRFKLPPGPLPVPIFGNWLQVGDDLNHRNLTALAKRFGDIFLLRMGQRNLVVVSSPELAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNRHGWEEEARRVVEDVMANPKAATEGIVLRRRLQLMMYNNMFRIMFDRRFESEDDPLFNKLRALNGERSRLAQSFEYNYGDFIPILRPFLKGYLKICQEVKDRRLQLFKTYFIDERKKLASTKGATNVELKCAIDHILEAERKGEINEDNVLYIVENINVAAIETTQWSIEWGIAELVNHPEIQRKLRRELDTVLGPGVQITEPDTQKLPYLQAVIKETLRRRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLANNPDNWKNPDEFRPERFLAEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKIDTAEKGGQFSLHILKHSTIVCKPRLV
>rna-XM_039133961.1
MDLVLLEKALLGLFAAVTLAIAASKLPGKRFGDDLNHRNRTALAKRFGDIFVLRMGQWNLVVVSSLEMARDVLHTQGVEFGSRTCNVVFDIFTGKGQDMVFTIYGEHWRKVCRIMTVPFFTNKVVQQNRHGWEEEARRVVEDVKAIPNAATELGGHFWRRRWWG
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University