Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Phaseolus vulgaris
Species name
French bean (Phaseolus vulgaris) is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Phaseolus_vulgaris.4CL.fa
Download
>rna-XM_007157005.1
MLSVAPSLDTNTKTDQTQIPQTTHVFKSKLPDIPISNHLSLHDYCFQNLSQFADRPCLIVGSASKTYTYAQTYLISRKIAAGFSNLGIRKGDVVMILLQNSAEFVLSFLAASMVGAVATTANPFYTAAEIFKQFTASKAKLIITQAMYVEKLRSHDAGWSLGEDFKVVTVDDPPENCLHFSVLSEANESDAPEVEIHPDDAVALPFSSGTTGLPKGVILTHKSLTTSVAQQVDGENPNLYLTTEDVLLCVLPLFHIFSLNSVLLCALRAGSGVLLMQKFEIGTLLELIQRYRVSVAMVVPPLVLALAKNPMVANFDLSSIRLVLSGAAPLGKELEEALHSRVPHAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVVDPETGRSLGYNQPGEICIRGLQIMKGYLNDDQATASTIDAEGWLHTGDVGYVDDDDEIFIVDRVKELIKFKGFQVPPAELEGLLVSHPSIADAAVVPQKDVVAGELPVAFVVRSNGFDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLEAAAAAAATPTP
>rna-XM_007154715.1
MPPTTPPPPPTMAPSPQEIIFRSPLPDIPIPTHLPLHSYCFQNLSQFQHRTCLIDGETGETLTYAEVDLAAHRIAAGLHNIGIRQGDVIMLVLRNCPQFALAFLGASHRGAVITTANPFYTPLELAKQAAATKTRLVITQSAYVDKIKSFADNNDVMVMCIDSEDDGVLHFSTLTNADETEAPAVKISPDDVVALPFSSGTSGLPKGVMLSHKNLVTTIAQLVDGENAHQYTHSEDVLLCVLPMFHIYALNSILLSGIRSGAAVLIVQKFEMTSLLELIQKYRVTVASFVPPIVLALVKSGEAHRYDLSSVRAVVTGAAPLGRELQEAVESRLPHATFGQGYGMTEAGPLAISMAFAKEPSNIKPGACGTVVRNAEMKIVDTETGVSLPKNETGEICIRGTKVMKGYLNDPEATERTIDKDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPNISEAAVVPMKDEAAGEIPVAFVVRSKGSEITEDEIKQYISQQVVFYKRIGRVFFTDSIPKAASGKILRKVLTARLNEGLVVAN
>rna-XM_007154714.1
MEQQQSTQLHNDDFIFRSKLPDIYIPTHLPLHTYIFQNISQFSHRPCLINAATGDCFTYAEVQLTSRRVAAGLNKLGIEKGDVILLLLQNCPQFVFAFLGSSFCGATVTTANPFYTPAEVAKQAAASNAKLIITQASYVDKVKDYAREKDVRVMCVDAAPEGYLAFSDLTEANERDIPGVKISPDDVVALPYSSGTTGLPKGVMLTHKGMVTSVAQQVDGENPNLYLRSEDVVLCVLPLFHIYSLNTVLLCSLRVGAAVLVMPKFEIASLLELVEKYKVSVAPFVPPIILAIAKTPDLERYDLSSIRMILSGAAPVGKELEDSVRAKLPHATLGQGYGMTEAGPVLSMSLAFAKEAVHVKSGSCGTVVRNAEMKIIDPHTAASLHRNQAGEICIRGNQIMKGYLNDEEATKITIDNDGWLHTGDIGYMDDDDQIFIVDRLKELIKYKGFQVAPAELEAMLIVHPNISEAVVVSMKDEVAGEVPVAFVVLSNGSKISEEEIKQYISKQVVFYKRISRVFFVGSIPKAASGKILRRELRARLANGLPSS
>rna-XM_007150091.1
MQRSGYGSDGIFRSLRPSIALPKQPNLTLVSHLFNRVAPFPSKHALIDADSSQTLSFAQLKSLTVKVSHGLLRLGVAKNDVVLFLAPNDIRYIVCFLAVTSLGAIVTTVNPAYTAAEVAKQAKDSNPKFVVTVPELWDKLQHLNLPAVFLHSRAHSNATSFDALVHLAGSPTEFPKVDVKQSDTAVLLYSSGTTGLSKGVVLTHGNFVAASLMIGLDDDLAGEMHSVFLCVLPMFHVFGLMVISYSQLQRGSAVVSLKKFEFELVLKTIEKFSVTHLWVVPPIILALAKHGLVDKYDLSSLKHIGSGAAPLGKELMEECAKRFPRATVAQGYGMTETCGIVSVENTRLGIRHSGSAGMLVAGVEAQIVSVDTLKALPPGQLGEIWVRGPNMMQGYHNNPQATRLTIDKKGWVHTGDLGYFDEDGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEEDVQKFIAKQVAPFKRLRRVTFINAVPKTASGKILRRELIEKVRSKI
>rna-XM_007150770.1
MAVETQQGKDFIFRSKLPDIYIPKHLPLHAYCFQNLPDHASRPCLINAPTGEVYTYSDVDATARKVAAGLHKLGVRQGEVIMILLPNCPEFVFAFLGASHRGAMATAANPFFTAAEIAKQAKASNAKVLITQASYYEKVKELEEVKLVFVDSCPAAEADGGGHIHFSELCEGGGEMDEVDIRADDVVALPYSSGTTGLPKGVMLTHKGLVTSIAQQVDGENPNLYYHSDDTILCVLPLFHIYSLNSVLLCGLRSKAAILLMPKFEIKALLALIHKHRVTVAAVVPPIVLAIARSPDLASYDLSSIRLFKSGGAPLGKDLEDSVRSKFPTARLGQGYGMTEAGPVLTMSLAFAKEAMHVKAGACGTVVRNAEMKIVDPETAQSLPRNHSGEICIRGDQIMKGYLNDKEATERTIDKEGWLHTGDIGYIDEDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPNISDAAVVPMKDEAAGEVPVAFVVRSNACIDTTQDEIKHFISKQVVFYKRISTVFFVDAIPKSPSGKILRKDLRAKLAAPAAVSK
>rna-XM_007146580.1
MQHLVNCLSTHNTNMGTYVESLSGVEEHVFRSQYSPVPIPDNVTLPEYVLQNAELYGEKVAFVDAVTGKGVSYREVVRDVDRFSKALRSLGLRKGHVVIVVLPNVVEYAIVALGIMAAGGVFSGANPSSHVSEIKKQAESADAKLIVTNSSNYEKVKGLELPVIVLGDEVVEGGMNWNKLLEAADRAGDDFAKEPIHQNDLCAMPFSSGTTGMSKGVMLTHRNLVANLCSTLFTVTKEMEGLVTTLGLIPFFHIYGITGICCATLRSKGKVVVMGRFELKKFLNALITHEVTFAPIVPPIILSLVKNPIVDEFDLSKLKLQAIMTAAAPLAPELLNAFEHKFPGVSVQEAYGLTEHSCITLTLAQKGLGSLHKNSVGFVLPNLEVKFVDPDTGRSLPRNTPGELCVRSQCVMQGYYKQVDETAQTIDKNGWLHTGDIGFIDDEENVFIIDRIKELIKYKGFQVAPAELEAILLSHSSVEDAAVVPLPDEEAGEIPAASVVLSPGAKESEEDIMNYVANNAAHYKKVRVVHFVETIPKSPSGKIMRRLIKEKMVEKIKTSSLIKSENV
>rna-XM_007132252.1
MNSAIHRSGYCSDGTYRSQRPSLVLPDNPNLSLVSFLFQSVSSFPSKTALVDADSSQTLTFAQLKARVATLAHGFLKLGIKKNDVVLLLAPNTIHFPVCFLAATAIGAIVSTANPIYTVHELSNQVKDSNPKLVITVPELCDKAKNLNLPAVILSTNNLQNPTKNVSGKITSLEAVMEMAGPVTELPESGVKQGDTAALLYSSGTTGLSKGVVLTHGNFIAASVMISMDDDLAGEVNDVFLCVLPMFHVFGLAVVTYTALRRGSAVVSMGKFELEAFLKAIEKHRVTKLWLVPPILLAMAKQSVVQSYDLSSLKRIGSGAAPLGKELMQECGRRFPHVAICQGYGMTETCGIVSVENPRAGIRHTGSTGMLASGVEAQIVTVDTQKPLPPTQSGEIWVRGPNMMKGYHNNPQATRLTIDEKGWVHTGDIGYFDEDGQLYVVDRIKELIKYKGFQVAPAELEGLLISHPEILDAVVVPYPDDEAGEVPIAYVVRSPNSSLTEEEIKKFIANQVAPFKKLRRVTFISSVPRTSSGKILRREITAKARSKI
>rna-XM_007131463.1
MSERAEPETPQTHIFRSKLPDIPLPNNLLLHTYCFLKLPQVSHRTCLIAAARTYTYAETHSASRKVAAGMSKLGIQKGDAVMILLPNSPEFVFSFMAASMLGAVATTANPSYTAAEIAKQLAASNAKLVVTLSENVPKLHQQERQHFFKVVTVDDPPENCTRFPEGDESGVPEVEISAEDAVALPFSSGTTGLAKGVILTHKSLVTSVAQQMEGENPNMYLKEEDVVLCVLPLFHIFSMHIAMMCALRAGSAILLIEKFEMRKLLEAIERQRVTVAIVVPPLVAALTKNSTVEEYDLRSIRLVISGAAPLGQQAEEALRKRLPNAILGQGYGMTEGGPVLTMSLGFAKYPFPTKSGSCGTVIRNGELKIIDPLTSFSLPRNHSGEICVRGPQIMKGYLNDEEATAAAIDGDGWLHTGDIGYVDDDDEVFLVDRAKELIKFKGFQVPPAELEDLLMRHPSIADAAVVPQNDDAAGEVPVAFVVSFDLTEDAVKDFIAKQVVFYKRLHKVYFVDEIPKSSTGKILRKELRAKVGSIIQRT
MLSVAPSLDTNTKTDQTQIPQTTHVFKSKLPDIPISNHLSLHDYCFQNLSQFADRPCLIVGSASKTYTYAQTYLISRKIAAGFSNLGIRKGDVVMILLQNSAEFVLSFLAASMVGAVATTANPFYTAAEIFKQFTASKAKLIITQAMYVEKLRSHDAGWSLGEDFKVVTVDDPPENCLHFSVLSEANESDAPEVEIHPDDAVALPFSSGTTGLPKGVILTHKSLTTSVAQQVDGENPNLYLTTEDVLLCVLPLFHIFSLNSVLLCALRAGSGVLLMQKFEIGTLLELIQRYRVSVAMVVPPLVLALAKNPMVANFDLSSIRLVLSGAAPLGKELEEALHSRVPHAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVVDPETGRSLGYNQPGEICIRGLQIMKGYLNDDQATASTIDAEGWLHTGDVGYVDDDDEIFIVDRVKELIKFKGFQVPPAELEGLLVSHPSIADAAVVPQKDVVAGELPVAFVVRSNGFDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLEAAAAAAATPTP
>rna-XM_007154715.1
MPPTTPPPPPTMAPSPQEIIFRSPLPDIPIPTHLPLHSYCFQNLSQFQHRTCLIDGETGETLTYAEVDLAAHRIAAGLHNIGIRQGDVIMLVLRNCPQFALAFLGASHRGAVITTANPFYTPLELAKQAAATKTRLVITQSAYVDKIKSFADNNDVMVMCIDSEDDGVLHFSTLTNADETEAPAVKISPDDVVALPFSSGTSGLPKGVMLSHKNLVTTIAQLVDGENAHQYTHSEDVLLCVLPMFHIYALNSILLSGIRSGAAVLIVQKFEMTSLLELIQKYRVTVASFVPPIVLALVKSGEAHRYDLSSVRAVVTGAAPLGRELQEAVESRLPHATFGQGYGMTEAGPLAISMAFAKEPSNIKPGACGTVVRNAEMKIVDTETGVSLPKNETGEICIRGTKVMKGYLNDPEATERTIDKDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPNISEAAVVPMKDEAAGEIPVAFVVRSKGSEITEDEIKQYISQQVVFYKRIGRVFFTDSIPKAASGKILRKVLTARLNEGLVVAN
>rna-XM_007154714.1
MEQQQSTQLHNDDFIFRSKLPDIYIPTHLPLHTYIFQNISQFSHRPCLINAATGDCFTYAEVQLTSRRVAAGLNKLGIEKGDVILLLLQNCPQFVFAFLGSSFCGATVTTANPFYTPAEVAKQAAASNAKLIITQASYVDKVKDYAREKDVRVMCVDAAPEGYLAFSDLTEANERDIPGVKISPDDVVALPYSSGTTGLPKGVMLTHKGMVTSVAQQVDGENPNLYLRSEDVVLCVLPLFHIYSLNTVLLCSLRVGAAVLVMPKFEIASLLELVEKYKVSVAPFVPPIILAIAKTPDLERYDLSSIRMILSGAAPVGKELEDSVRAKLPHATLGQGYGMTEAGPVLSMSLAFAKEAVHVKSGSCGTVVRNAEMKIIDPHTAASLHRNQAGEICIRGNQIMKGYLNDEEATKITIDNDGWLHTGDIGYMDDDDQIFIVDRLKELIKYKGFQVAPAELEAMLIVHPNISEAVVVSMKDEVAGEVPVAFVVLSNGSKISEEEIKQYISKQVVFYKRISRVFFVGSIPKAASGKILRRELRARLANGLPSS
>rna-XM_007150091.1
MQRSGYGSDGIFRSLRPSIALPKQPNLTLVSHLFNRVAPFPSKHALIDADSSQTLSFAQLKSLTVKVSHGLLRLGVAKNDVVLFLAPNDIRYIVCFLAVTSLGAIVTTVNPAYTAAEVAKQAKDSNPKFVVTVPELWDKLQHLNLPAVFLHSRAHSNATSFDALVHLAGSPTEFPKVDVKQSDTAVLLYSSGTTGLSKGVVLTHGNFVAASLMIGLDDDLAGEMHSVFLCVLPMFHVFGLMVISYSQLQRGSAVVSLKKFEFELVLKTIEKFSVTHLWVVPPIILALAKHGLVDKYDLSSLKHIGSGAAPLGKELMEECAKRFPRATVAQGYGMTETCGIVSVENTRLGIRHSGSAGMLVAGVEAQIVSVDTLKALPPGQLGEIWVRGPNMMQGYHNNPQATRLTIDKKGWVHTGDLGYFDEDGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEEDVQKFIAKQVAPFKRLRRVTFINAVPKTASGKILRRELIEKVRSKI
>rna-XM_007150770.1
MAVETQQGKDFIFRSKLPDIYIPKHLPLHAYCFQNLPDHASRPCLINAPTGEVYTYSDVDATARKVAAGLHKLGVRQGEVIMILLPNCPEFVFAFLGASHRGAMATAANPFFTAAEIAKQAKASNAKVLITQASYYEKVKELEEVKLVFVDSCPAAEADGGGHIHFSELCEGGGEMDEVDIRADDVVALPYSSGTTGLPKGVMLTHKGLVTSIAQQVDGENPNLYYHSDDTILCVLPLFHIYSLNSVLLCGLRSKAAILLMPKFEIKALLALIHKHRVTVAAVVPPIVLAIARSPDLASYDLSSIRLFKSGGAPLGKDLEDSVRSKFPTARLGQGYGMTEAGPVLTMSLAFAKEAMHVKAGACGTVVRNAEMKIVDPETAQSLPRNHSGEICIRGDQIMKGYLNDKEATERTIDKEGWLHTGDIGYIDEDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPNISDAAVVPMKDEAAGEVPVAFVVRSNACIDTTQDEIKHFISKQVVFYKRISTVFFVDAIPKSPSGKILRKDLRAKLAAPAAVSK
>rna-XM_007146580.1
MQHLVNCLSTHNTNMGTYVESLSGVEEHVFRSQYSPVPIPDNVTLPEYVLQNAELYGEKVAFVDAVTGKGVSYREVVRDVDRFSKALRSLGLRKGHVVIVVLPNVVEYAIVALGIMAAGGVFSGANPSSHVSEIKKQAESADAKLIVTNSSNYEKVKGLELPVIVLGDEVVEGGMNWNKLLEAADRAGDDFAKEPIHQNDLCAMPFSSGTTGMSKGVMLTHRNLVANLCSTLFTVTKEMEGLVTTLGLIPFFHIYGITGICCATLRSKGKVVVMGRFELKKFLNALITHEVTFAPIVPPIILSLVKNPIVDEFDLSKLKLQAIMTAAAPLAPELLNAFEHKFPGVSVQEAYGLTEHSCITLTLAQKGLGSLHKNSVGFVLPNLEVKFVDPDTGRSLPRNTPGELCVRSQCVMQGYYKQVDETAQTIDKNGWLHTGDIGFIDDEENVFIIDRIKELIKYKGFQVAPAELEAILLSHSSVEDAAVVPLPDEEAGEIPAASVVLSPGAKESEEDIMNYVANNAAHYKKVRVVHFVETIPKSPSGKIMRRLIKEKMVEKIKTSSLIKSENV
>rna-XM_007132252.1
MNSAIHRSGYCSDGTYRSQRPSLVLPDNPNLSLVSFLFQSVSSFPSKTALVDADSSQTLTFAQLKARVATLAHGFLKLGIKKNDVVLLLAPNTIHFPVCFLAATAIGAIVSTANPIYTVHELSNQVKDSNPKLVITVPELCDKAKNLNLPAVILSTNNLQNPTKNVSGKITSLEAVMEMAGPVTELPESGVKQGDTAALLYSSGTTGLSKGVVLTHGNFIAASVMISMDDDLAGEVNDVFLCVLPMFHVFGLAVVTYTALRRGSAVVSMGKFELEAFLKAIEKHRVTKLWLVPPILLAMAKQSVVQSYDLSSLKRIGSGAAPLGKELMQECGRRFPHVAICQGYGMTETCGIVSVENPRAGIRHTGSTGMLASGVEAQIVTVDTQKPLPPTQSGEIWVRGPNMMKGYHNNPQATRLTIDEKGWVHTGDIGYFDEDGQLYVVDRIKELIKYKGFQVAPAELEGLLISHPEILDAVVVPYPDDEAGEVPIAYVVRSPNSSLTEEEIKKFIANQVAPFKKLRRVTFISSVPRTSSGKILRREITAKARSKI
>rna-XM_007131463.1
MSERAEPETPQTHIFRSKLPDIPLPNNLLLHTYCFLKLPQVSHRTCLIAAARTYTYAETHSASRKVAAGMSKLGIQKGDAVMILLPNSPEFVFSFMAASMLGAVATTANPSYTAAEIAKQLAASNAKLVVTLSENVPKLHQQERQHFFKVVTVDDPPENCTRFPEGDESGVPEVEISAEDAVALPFSSGTTGLAKGVILTHKSLVTSVAQQMEGENPNMYLKEEDVVLCVLPLFHIFSMHIAMMCALRAGSAILLIEKFEMRKLLEAIERQRVTVAIVVPPLVAALTKNSTVEEYDLRSIRLVISGAAPLGQQAEEALRKRLPNAILGQGYGMTEGGPVLTMSLGFAKYPFPTKSGSCGTVIRNGELKIIDPLTSFSLPRNHSGEICVRGPQIMKGYLNDEEATAAAIDGDGWLHTGDIGYVDDDDEVFLVDRAKELIKFKGFQVPPAELEDLLMRHPSIADAAVVPQNDDAAGEVPVAFVVSFDLTEDAVKDFIAKQVVFYKRLHKVYFVDEIPKSSTGKILRKELRAKVGSIIQRT
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University