Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Phalaenopsis equestris
Species name
Phalaenopsis equestris is a species of monocot in the family Orchidaceae (orchid family).
Species info
Gene sequence info
Phalaenopsis_equestris.COMT.fa
Download
>rna-XM_020734136.1
MAGPNSQLTAVEIAGNLPECRHEKAAIMLEPILGYLATHSLLTCTTNSSLKQYGLTPVSRLLTKNQPGASLAPLFLVGNQKPLTDTWDHMKEAVQEGVNPFKKTHGITFFEYMAKNPSFCELFNKGMASSSNMVIEKLVEEYGGLKQVKELVDVGGGDGTLLKMIISKYPHIKGINFDLPHVVSEAPSFPGVQHVGGDMFITIPSGGTILLKRVLHNWDDEKCLKILKNCWSALPTFGKVIIVEQILPEIIEGNVVAQDIYATNLIMMTIGDAKERTEQEYRSLAKKANFSQFKIACKVLNHHVLEFVK
>rna-XM_020744352.1
MRNITTKEDEAFAAAMQLCVSNIFCSAVKAAFDLGIFDILAMAGPNSQLTAVEIAGNLPECRHEKAAIMLEPILGYLATHSLLTCTTNSSLKQYGLTPVSRLLTKNNHGASLAPLMLVANQKAFIDSWDHLKEAVQEGVNPFKRTHGLTLFEYMAKNPSFCELFNKGMASSSNMVIEKLVEEYGGLKQVKELVDVGGGNGTSLKMIISKYPYIKGINFDLPHVVSEAPSFPGVQHVGGDMFIMIPSGGTILLKWILHDWNDEECLKILKNCWGALPTFGKVIIVEQILPEIIEENIVVQHSYAMNLIMMTIADAKERTEKEYRSLAKKANFSEFKIACKVLNHYVMEFVK
>rna-XM_020738744.1
MSDTQREDEEPFIAAMLLCYSKTFSRAVQAAFDLGIFEVLAEPGPKTQLTAREIAGNLSGCNHEKAAAMLDNILGYLASHSILTCTASSSDETGSPRKQYGLTPTSRLLAKNHDGLSLAPFMFMSHKKVYEDACWNQLKEALQEGVNPFKKAYGFTMYEYMDKNPTYSKVFNEGMASNSNIVTQKMLEKYEGLKQVTELVDVGGGIGTSLKNIISKYPHIKGINFDLPHVVSQAPSLPGVQHVGGDMFIMIPSGEAIFLKWILHNWNDEKCLLILKNCWKALPTSGKVILMEHILPEFPETNISTQQIYTMNMIMTMFFEAKVRTEREYQSLAHEAGFSGFKILCKIFNYHIMEFLK
>rna-XM_020727989.1
MSDTQREEEEPFIAAMLLCYSQTFSRTVQAAFDLGIFEILAEPGPNTQLTACEIAGKLSGCNHEKAATMLDNILGYLASHSILTCTASSSSNETGRLRKQYGLTPMSRLLAKNHDGPSLAPFMFMTNLMTFEDTWKQLKEALQEGVSPFKKAHGLTTYEFFAKNPTYSDVFNEAMASNGNIVMEKMVEEYEGLKQVTELIDVGGGIGTSLKKIISKYPHIKGINFDLPHVVSEAPALPGVQHVGGDMFIMIPSGEAIFLKWILHNWNDEKCLLILKNCWRALPTYGKVILMEHILPEFPEANITTQQIYTMNMIMTIYFEAKVRTEKEYRSLAHKAGFSEFKILCKVFDYHVMEFLK
>rna-XM_020715673.1
MAATGGEIKKSARLAMMEISNMLSVPMALNAIVRLNVPEAIWQSGSNSPLTAAEILARLNPPPPSSASPSNLQRLLRLLSSHNVFSEHLDGGHRRYNLTEIGRTLVADDDEANGGVSYAPYVLQHHQDALVRAWPRLHEAILDPDGPEPFSRANGGVSAYAYYGGDDAANDLMRRAMWGVSVPFMEAFLDEYGLAGGLEGVGTIVDVGGSSGACLQMIMRRFPAVKTGINFDLPEVVSGAPEFPGIIHVGGDMFKSIPSGDAIFMKWVLTTWTDEECGLILKNCYNALPAGGKLIACEPVLPEETDSSRRTRALLEGDIFVMTIYRSQGKERTEEEFKQLGCSAGFPNFRALYFDPFYTVLEFQK
>rna-XM_020719110.1
MEPSTPAQLQDDEAAYLATLQLLSYHGVAMAVKAAIELDIFNILARSGPDTFLSAGEIACQISNSDPSKTAPRLDRVLRFLASHSVLRFSSACSASSTGAIERRYALEPIYRFLAKNKDGVSLAPAFLVTRDQASLGSWQYLKDAVLEDIDPFTKANGSDPFEYMATKDRRFGELFCEYMASVTKLTSGNIVEAYKGFEFLSEVVDVGGGEGTMLGLIISRYPHIKGINFDLPHVISSAPNIPGVEYVAGDFLSSIPSGDALLLKFVLHDWSDEDCIRILKNCYKALPITGKVIVVEQILPEIPERNNAVRDVYFMDLSMMVTNHRAKERSEKEFISLASEAGFAEFKIACCVMNYHVMEFIK
>rna-XM_020722229.1
MGSHNTNADGPRDDEAACLYAMQLISFSVLPMTLKAAIELKLLETISLAGPGALLSPAEIASRIPSISNPQAPIMLDRILRLLASYSIITCSVSPSGERRYGPAPVCKYLTPNDDGVSMAALSLMNQDKVLMESWYHLKDAVIEGGIPFNKAYGMTAFEYHGTDPRFNKVFNNGMSGHSTIITNKLLEIYEGFDGLGSLVDVGGGVGATLGKITAKYGGIRGINFDLPHVISEAPPLPRVEHVGGDMFESVPAADAIFMKWILHDWSDDHCLKLLKNCWKALPENGKVIVAECILPEEPEQSVAARGVFHLDLIMLAHNPGGKERTEKEFDSLAKKAGFSQLKSIYIFAGTWVMEFIK
>rna-XM_020723648.1
MGSESHQIQILKICSYSVFPMTLTTAIELGLFKLLSDAGPGAQLSAEELAAKLIHDSANEYTASKLERILRLLASHSVLSWSTVTDGHGRAVRRYGASPACKYLVPDEAGVSLASLSLMSTDWVTMQSWYHLKDAILHGGVAFNRAHDGLNEFEYHAKDPRFSKVFNDGMRSHSITIMKNILEVYKGFEDINVLVDVCGGTGGTLSMITTKHKHIKGINFDLPHVIAQAPALPGVEHVGGDVFESIPSGDALLLKWVLHDWNDEDCLKILSNCWKAIPNRGKVIVVDSILPETLDSTDLTHCVLHTDVIMLLESPSGKERTEKEFWALAKQSGFSDFSILCNFSNAWIMEFFK
>rna-XM_020723616.1
MGSESLPTIQTEMDACNYAITLCSFSVLPMALSTAIELGLFKILSAAGPGAQLSAEDFAAKLINDATGEHVASKLERILRALASHRVFTCSTESDEHGRTVHRYGATLVCKYFTPNEDGVSLASLAMMSNDWITMESWYHLKDAILHGGVAFNRAHDGLNEFEYHAKDPRFSKVFNDGMRSHSIIIMKNILEVYKGFENINVLVDVCGGTGGTLSMITTKHKHIKGINFDLPHVIAQAPALPGVEHVGGDVFESIPNGDALFLKWVLHDWDDEDSLKILKNCWKAVPENGKVIIVDSILPETPDSTDLTHCILHADVIMLLESPSGRERTEKEFRALAKKAGFSGFSILCNFSNASIMELSK
>rna-XM_020738917.1
IPADVGVEHVGGDVFESIPNGDALFLKWVLHDWDDEDSLKILKNCWKAVPENGKVIIVDSILPETPDSTDLTHCILHADVIMLLESPSGRERTEKEFRALAKKAGFSGFSILCNFSNASIMELSK
MAGPNSQLTAVEIAGNLPECRHEKAAIMLEPILGYLATHSLLTCTTNSSLKQYGLTPVSRLLTKNQPGASLAPLFLVGNQKPLTDTWDHMKEAVQEGVNPFKKTHGITFFEYMAKNPSFCELFNKGMASSSNMVIEKLVEEYGGLKQVKELVDVGGGDGTLLKMIISKYPHIKGINFDLPHVVSEAPSFPGVQHVGGDMFITIPSGGTILLKRVLHNWDDEKCLKILKNCWSALPTFGKVIIVEQILPEIIEGNVVAQDIYATNLIMMTIGDAKERTEQEYRSLAKKANFSQFKIACKVLNHHVLEFVK
>rna-XM_020744352.1
MRNITTKEDEAFAAAMQLCVSNIFCSAVKAAFDLGIFDILAMAGPNSQLTAVEIAGNLPECRHEKAAIMLEPILGYLATHSLLTCTTNSSLKQYGLTPVSRLLTKNNHGASLAPLMLVANQKAFIDSWDHLKEAVQEGVNPFKRTHGLTLFEYMAKNPSFCELFNKGMASSSNMVIEKLVEEYGGLKQVKELVDVGGGNGTSLKMIISKYPYIKGINFDLPHVVSEAPSFPGVQHVGGDMFIMIPSGGTILLKWILHDWNDEECLKILKNCWGALPTFGKVIIVEQILPEIIEENIVVQHSYAMNLIMMTIADAKERTEKEYRSLAKKANFSEFKIACKVLNHYVMEFVK
>rna-XM_020738744.1
MSDTQREDEEPFIAAMLLCYSKTFSRAVQAAFDLGIFEVLAEPGPKTQLTAREIAGNLSGCNHEKAAAMLDNILGYLASHSILTCTASSSDETGSPRKQYGLTPTSRLLAKNHDGLSLAPFMFMSHKKVYEDACWNQLKEALQEGVNPFKKAYGFTMYEYMDKNPTYSKVFNEGMASNSNIVTQKMLEKYEGLKQVTELVDVGGGIGTSLKNIISKYPHIKGINFDLPHVVSQAPSLPGVQHVGGDMFIMIPSGEAIFLKWILHNWNDEKCLLILKNCWKALPTSGKVILMEHILPEFPETNISTQQIYTMNMIMTMFFEAKVRTEREYQSLAHEAGFSGFKILCKIFNYHIMEFLK
>rna-XM_020727989.1
MSDTQREEEEPFIAAMLLCYSQTFSRTVQAAFDLGIFEILAEPGPNTQLTACEIAGKLSGCNHEKAATMLDNILGYLASHSILTCTASSSSNETGRLRKQYGLTPMSRLLAKNHDGPSLAPFMFMTNLMTFEDTWKQLKEALQEGVSPFKKAHGLTTYEFFAKNPTYSDVFNEAMASNGNIVMEKMVEEYEGLKQVTELIDVGGGIGTSLKKIISKYPHIKGINFDLPHVVSEAPALPGVQHVGGDMFIMIPSGEAIFLKWILHNWNDEKCLLILKNCWRALPTYGKVILMEHILPEFPEANITTQQIYTMNMIMTIYFEAKVRTEKEYRSLAHKAGFSEFKILCKVFDYHVMEFLK
>rna-XM_020715673.1
MAATGGEIKKSARLAMMEISNMLSVPMALNAIVRLNVPEAIWQSGSNSPLTAAEILARLNPPPPSSASPSNLQRLLRLLSSHNVFSEHLDGGHRRYNLTEIGRTLVADDDEANGGVSYAPYVLQHHQDALVRAWPRLHEAILDPDGPEPFSRANGGVSAYAYYGGDDAANDLMRRAMWGVSVPFMEAFLDEYGLAGGLEGVGTIVDVGGSSGACLQMIMRRFPAVKTGINFDLPEVVSGAPEFPGIIHVGGDMFKSIPSGDAIFMKWVLTTWTDEECGLILKNCYNALPAGGKLIACEPVLPEETDSSRRTRALLEGDIFVMTIYRSQGKERTEEEFKQLGCSAGFPNFRALYFDPFYTVLEFQK
>rna-XM_020719110.1
MEPSTPAQLQDDEAAYLATLQLLSYHGVAMAVKAAIELDIFNILARSGPDTFLSAGEIACQISNSDPSKTAPRLDRVLRFLASHSVLRFSSACSASSTGAIERRYALEPIYRFLAKNKDGVSLAPAFLVTRDQASLGSWQYLKDAVLEDIDPFTKANGSDPFEYMATKDRRFGELFCEYMASVTKLTSGNIVEAYKGFEFLSEVVDVGGGEGTMLGLIISRYPHIKGINFDLPHVISSAPNIPGVEYVAGDFLSSIPSGDALLLKFVLHDWSDEDCIRILKNCYKALPITGKVIVVEQILPEIPERNNAVRDVYFMDLSMMVTNHRAKERSEKEFISLASEAGFAEFKIACCVMNYHVMEFIK
>rna-XM_020722229.1
MGSHNTNADGPRDDEAACLYAMQLISFSVLPMTLKAAIELKLLETISLAGPGALLSPAEIASRIPSISNPQAPIMLDRILRLLASYSIITCSVSPSGERRYGPAPVCKYLTPNDDGVSMAALSLMNQDKVLMESWYHLKDAVIEGGIPFNKAYGMTAFEYHGTDPRFNKVFNNGMSGHSTIITNKLLEIYEGFDGLGSLVDVGGGVGATLGKITAKYGGIRGINFDLPHVISEAPPLPRVEHVGGDMFESVPAADAIFMKWILHDWSDDHCLKLLKNCWKALPENGKVIVAECILPEEPEQSVAARGVFHLDLIMLAHNPGGKERTEKEFDSLAKKAGFSQLKSIYIFAGTWVMEFIK
>rna-XM_020723648.1
MGSESHQIQILKICSYSVFPMTLTTAIELGLFKLLSDAGPGAQLSAEELAAKLIHDSANEYTASKLERILRLLASHSVLSWSTVTDGHGRAVRRYGASPACKYLVPDEAGVSLASLSLMSTDWVTMQSWYHLKDAILHGGVAFNRAHDGLNEFEYHAKDPRFSKVFNDGMRSHSITIMKNILEVYKGFEDINVLVDVCGGTGGTLSMITTKHKHIKGINFDLPHVIAQAPALPGVEHVGGDVFESIPSGDALLLKWVLHDWNDEDCLKILSNCWKAIPNRGKVIVVDSILPETLDSTDLTHCVLHTDVIMLLESPSGKERTEKEFWALAKQSGFSDFSILCNFSNAWIMEFFK
>rna-XM_020723616.1
MGSESLPTIQTEMDACNYAITLCSFSVLPMALSTAIELGLFKILSAAGPGAQLSAEDFAAKLINDATGEHVASKLERILRALASHRVFTCSTESDEHGRTVHRYGATLVCKYFTPNEDGVSLASLAMMSNDWITMESWYHLKDAILHGGVAFNRAHDGLNEFEYHAKDPRFSKVFNDGMRSHSIIIMKNILEVYKGFENINVLVDVCGGTGGTLSMITTKHKHIKGINFDLPHVIAQAPALPGVEHVGGDVFESIPNGDALFLKWVLHDWDDEDSLKILKNCWKAVPENGKVIIVDSILPETPDSTDLTHCILHADVIMLLESPSGRERTEKEFRALAKKAGFSGFSILCNFSNASIMELSK
>rna-XM_020738917.1
IPADVGVEHVGGDVFESIPNGDALFLKWVLHDWDDEDSLKILKNCWKAVPENGKVIIVDSILPETPDSTDLTHCILHADVIMLLESPSGRERTEKEFRALAKKAGFSGFSILCNFSNASIMELSK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University