Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Perilla citriodora
Species name
Perilla frutescens var. hirtella is a varietas of beefsteak-mint (Perilla frutescens)
Species info
Gene sequence info
Perilla_citriodora.ROMT.fa
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>rna-gnl|WGS:QIYW|PC00007209_00028385_00031012.mrna1
MASANGVGVESSRKELLDAQAHVYNHTFNFVNSMCLNCVIQLGIPDIIHKHGKPMTLSQLADALPINKAKSHGLFRIMRILVHSKFFNKVRTIKDEDGDEDEDEGYCLTPVSRVLLRDDPISLAPYVLLKMDPIHIDSFHHLSEWLQDDCVNPFFTKHGKTFWELAGVDQDLNKKFNKAMACDAGFVTSVLTTDCRQVFEGLKSMVDLGGGTGETAKGIADAFPGLKCIVMDLPHVVAGLEGSENLSFCSGDMFESIPNADAVFLKWLLHDWSDEDCVKILKKCKEAITPNGGKVIIVEIILGDQIEDEKATQTQLFFDVLMMVGVKGKQRSEKEWGQLFSAAGFKHYKLTPALGLRSVIEFQEAKTELNTLFTAAKLCNVGFPTTILINDCSHVFRGLKSMVDGGDGGNCAASKVIADVFPGLKSTVLDLPHVATLQVCENLSFVSGDMFKLIPYVDLVFLKSIQQKHL
>rna-gnl|WGS:QIYW|chr10_48413386_48414548.mrna1
MAFLDIVDSSQELLDAQAHVWNHTFSYVNSMCLRCAIQLGIPDIIHEHDKPITLSQLVDALPMNKAKSHGLNRLMRILVHSKIFEKVNISEEEEEEAYSLTTASRLLLRDEPLSFAPFVLAMIDPIQMYSFHHLFEWFNDESPSPFHTKNGKDFWELAANEKKWNQVFNEAMASDARFVGSILVKECKHLFEGLNIVVDVAGGTGMVAKALADSFPSLKSIVLDLPHVVAGLEASENLRFVSGDMFQFIPPADAVLLKWILHNWSDEDCVKILEKCKEAIIPSRNNGGKVIILDMIVDGSKEKEKEIETQLHFDMIMMTFVTGKERSEKEWASLFFAAGFNNYKITPILGLRSVIEVFP
>rna-gnl|WGS:QIYW|chr06_14084539_14087774.mrna1
MAMANGVESSSTEELLDAQAHVWNHVFNYINSMSLKCAIQLGIPDAIHKHGKPMTLSQLADALPINGAKSDGLRRLMRILVHSKFFNKVNTTSFPEAVDVEAYSLTRASRLLLKDEPQSIVPHARAMLDPILMDPWHHLSEWFGNELATPFATKNGREFWEHAAVDKVMNVLFNEAMACDAGFVTSVLTTQCRGVFQDLKLMVDVGGGTGATAKGIAAAFPGLKCIVMDLPHVVAGLEGSENLSYVGGDMFDSIPTADAIFFKWILHDWNDIDCVKILKKCKEAISKSSAGKVIVVEMVMEDEKEEREATETKLFFDLEMMTIVTGKERTEKEWAKLFFAAGFRNYKITPVLGLRSVIELFP
>rna-gnl|WGS:QIYW|chr06_13997082_14000679.mrna1
MASPIVVDSTQELLDAQAHLWNLSFSHVNCMSLKCAVQLGIPDIIHKHGKPITLSELVDALSINKAKSNALSRLMRILVHSKIFDKVKISEEGEEEEAYSLTRASRLLLKDEPLSYTTFTVAMADPVMIDPFHHMTEWFHDECSTPFVTRNGMNFWEFGRNDEKWNQLFNEAMACDARFVGNMLVKECKHVFEGLKTVVDVAGGTGSVAKALIDTFSGLKCTVLDLPQVVAGLEGSENLRFVSGDMFQFIPPTDAVFLKWIMHDWSDENCVKILEKCKEAIIPSKNNGGKVIIVDMVVDGLKQEHHEATETQLFFDMTLMADLSGKERTEKEWAKLFAAAGFNNYKINPVLGLTSVIEVFP
>rna-gnl|WGS:QIYW|chr06_14171970_14173192.mrna1
MALQNGDTSYPNGELSTEQLLQAQAHVWNHTFAFINSMSLKCAIQLGIPDIIHKHGEPMSLSQLVESIPADKAKSQSIHRLMRVLVHSNFFIEDGGSDDHEETRYWLTPASRLLLKEAPLSVAPLVLLVLDPMLTKPWHHMSEWLANECHPTQFEAAHGLAFWERAAHEPSMGSLFDEAMCSDSRLVARVLVRDYKHVLDGIESLVDIGGGTGTMAKAIVDALSGMKCIVVDLPHVVAGLKSTDNLSFVGGDMFETIPPADAVLLKWIMHDWDDESCLKILKRCKDAVTSNGTRGKVMIIDVVVDINKEDDEVVGDQLYFDMAMMSYFNGKERSEKEWAKLLSDAGFTSYKITPAFGVRSLIEVYP
>rna-gnl|WGS:QIYW|chr06_14054661_14056660.mrna1
MAFPSNEVESTQDLLDAQSHVWNHIFHHINSMSLKCAIQLGIPDVIHKHGNPMTVSQLTNALPINKAKSPCLHRLIRILVHSKFLDKVKTTLSEDEDEEEAYCLTRASRLLLRCEPMSMAPFALAMFDSVKMDPWHHMSEWFQNEDSSPFFTKHGMTIFEYAGNDQRLNGLFNEAMASDAGFVTSVLSKECRHVFEGLKSMVDVGGGTGATAKGIAAAFPGLKCIVLDLPHVVADLEGSENLSFFSGDMFEFIPPADAVFLKWLLHDWSDEDCIKILRKCKEAISPGGKVIIVEIVVGDQKQDNRATETQFFFDLQVMVQINGRERSEKDWANLFSTAGFKNYKITHVLGLRSVIEVFP
>rna-gnl|WGS:QIYW|chr06_13884071_13885342.mrna1
MALTNEVESSVEELLNAQAHVWNHIFNHINSMSLKCAIQLGIPDVIHKHGKPMTLSQLAVALSIKEAKSHGLYRVMRILVHSQFFDKVKMTLSEGESEEEEEEEEAYCLTRASRLLLRNEPLSMAPYVRAMLDPNFMDPFHHLSEWLRNKCPSPFVLKHGKTIWEYAGIEPSWNQLFNESMANDARLVTSILVKECRQVFEGLGTMVDVGGGTGGVARTVTDAFPGLKGIVLDLPHVVANLQNSENLRYVGGDMFDSIPHADAVLLKWILHDWSDEACVKLLEKCKEAITPNGGKVIVVEMILDDKKGDHKATETQLFFDALMMTANIGKERSEKEWANLFFAAGFKTYKIHPVLRLRSVIEVFP
>rna-gnl|WGS:QIYW|chr06_14162414_14164175.mrna1
MASANGVGAESSRKELLDAQAHVYNHTFNFINSMSLNCAIQLGIPDIIHKHGKPMTLSQLADALPINKAKSHGLFRVMRILVHSKFFNKDVDEEEAYCLTQASRLLLRDDPISLAPYVISMIDPIMMDPFHHLSEWLQDECLNPVFTKHGKTFWELAGVDQNLNKKFNEAMACDAGFVTSILTTDCRQVFEGLESMVDVGGGTGETAMAKGIADAFPGLKCIVLDLPHVVGGLEGCENLRFFSGDMFESIPNADAVFLKWILHDWSDEECVKILKKCKEAITPNGGKVIIVEMILEDQIEDEKATQTQFFFDVLMMVGLTGKQRSEKEWSQLFSAAGFGHYKMNPAALGLRSVIEVFP
>rna-gnl|WGS:QIYW|chr06_13953023_13953920.mrna1
MSAAARGAMAKALVDTFSGLKCTVLDLPQVVAGLEGSNNLRFVSGDMFQFIPPTDAVFLKRIMHDWSDENCVKILGKCKEAIIPSKNNGGKFVHNMEHRTVKHLIITQVSYEEGS
MASANGVGVESSRKELLDAQAHVYNHTFNFVNSMCLNCVIQLGIPDIIHKHGKPMTLSQLADALPINKAKSHGLFRIMRILVHSKFFNKVRTIKDEDGDEDEDEGYCLTPVSRVLLRDDPISLAPYVLLKMDPIHIDSFHHLSEWLQDDCVNPFFTKHGKTFWELAGVDQDLNKKFNKAMACDAGFVTSVLTTDCRQVFEGLKSMVDLGGGTGETAKGIADAFPGLKCIVMDLPHVVAGLEGSENLSFCSGDMFESIPNADAVFLKWLLHDWSDEDCVKILKKCKEAITPNGGKVIIVEIILGDQIEDEKATQTQLFFDVLMMVGVKGKQRSEKEWGQLFSAAGFKHYKLTPALGLRSVIEFQEAKTELNTLFTAAKLCNVGFPTTILINDCSHVFRGLKSMVDGGDGGNCAASKVIADVFPGLKSTVLDLPHVATLQVCENLSFVSGDMFKLIPYVDLVFLKSIQQKHL
>rna-gnl|WGS:QIYW|chr10_48413386_48414548.mrna1
MAFLDIVDSSQELLDAQAHVWNHTFSYVNSMCLRCAIQLGIPDIIHEHDKPITLSQLVDALPMNKAKSHGLNRLMRILVHSKIFEKVNISEEEEEEAYSLTTASRLLLRDEPLSFAPFVLAMIDPIQMYSFHHLFEWFNDESPSPFHTKNGKDFWELAANEKKWNQVFNEAMASDARFVGSILVKECKHLFEGLNIVVDVAGGTGMVAKALADSFPSLKSIVLDLPHVVAGLEASENLRFVSGDMFQFIPPADAVLLKWILHNWSDEDCVKILEKCKEAIIPSRNNGGKVIILDMIVDGSKEKEKEIETQLHFDMIMMTFVTGKERSEKEWASLFFAAGFNNYKITPILGLRSVIEVFP
>rna-gnl|WGS:QIYW|chr06_14084539_14087774.mrna1
MAMANGVESSSTEELLDAQAHVWNHVFNYINSMSLKCAIQLGIPDAIHKHGKPMTLSQLADALPINGAKSDGLRRLMRILVHSKFFNKVNTTSFPEAVDVEAYSLTRASRLLLKDEPQSIVPHARAMLDPILMDPWHHLSEWFGNELATPFATKNGREFWEHAAVDKVMNVLFNEAMACDAGFVTSVLTTQCRGVFQDLKLMVDVGGGTGATAKGIAAAFPGLKCIVMDLPHVVAGLEGSENLSYVGGDMFDSIPTADAIFFKWILHDWNDIDCVKILKKCKEAISKSSAGKVIVVEMVMEDEKEEREATETKLFFDLEMMTIVTGKERTEKEWAKLFFAAGFRNYKITPVLGLRSVIELFP
>rna-gnl|WGS:QIYW|chr06_13997082_14000679.mrna1
MASPIVVDSTQELLDAQAHLWNLSFSHVNCMSLKCAVQLGIPDIIHKHGKPITLSELVDALSINKAKSNALSRLMRILVHSKIFDKVKISEEGEEEEAYSLTRASRLLLKDEPLSYTTFTVAMADPVMIDPFHHMTEWFHDECSTPFVTRNGMNFWEFGRNDEKWNQLFNEAMACDARFVGNMLVKECKHVFEGLKTVVDVAGGTGSVAKALIDTFSGLKCTVLDLPQVVAGLEGSENLRFVSGDMFQFIPPTDAVFLKWIMHDWSDENCVKILEKCKEAIIPSKNNGGKVIIVDMVVDGLKQEHHEATETQLFFDMTLMADLSGKERTEKEWAKLFAAAGFNNYKINPVLGLTSVIEVFP
>rna-gnl|WGS:QIYW|chr06_14171970_14173192.mrna1
MALQNGDTSYPNGELSTEQLLQAQAHVWNHTFAFINSMSLKCAIQLGIPDIIHKHGEPMSLSQLVESIPADKAKSQSIHRLMRVLVHSNFFIEDGGSDDHEETRYWLTPASRLLLKEAPLSVAPLVLLVLDPMLTKPWHHMSEWLANECHPTQFEAAHGLAFWERAAHEPSMGSLFDEAMCSDSRLVARVLVRDYKHVLDGIESLVDIGGGTGTMAKAIVDALSGMKCIVVDLPHVVAGLKSTDNLSFVGGDMFETIPPADAVLLKWIMHDWDDESCLKILKRCKDAVTSNGTRGKVMIIDVVVDINKEDDEVVGDQLYFDMAMMSYFNGKERSEKEWAKLLSDAGFTSYKITPAFGVRSLIEVYP
>rna-gnl|WGS:QIYW|chr06_14054661_14056660.mrna1
MAFPSNEVESTQDLLDAQSHVWNHIFHHINSMSLKCAIQLGIPDVIHKHGNPMTVSQLTNALPINKAKSPCLHRLIRILVHSKFLDKVKTTLSEDEDEEEAYCLTRASRLLLRCEPMSMAPFALAMFDSVKMDPWHHMSEWFQNEDSSPFFTKHGMTIFEYAGNDQRLNGLFNEAMASDAGFVTSVLSKECRHVFEGLKSMVDVGGGTGATAKGIAAAFPGLKCIVLDLPHVVADLEGSENLSFFSGDMFEFIPPADAVFLKWLLHDWSDEDCIKILRKCKEAISPGGKVIIVEIVVGDQKQDNRATETQFFFDLQVMVQINGRERSEKDWANLFSTAGFKNYKITHVLGLRSVIEVFP
>rna-gnl|WGS:QIYW|chr06_13884071_13885342.mrna1
MALTNEVESSVEELLNAQAHVWNHIFNHINSMSLKCAIQLGIPDVIHKHGKPMTLSQLAVALSIKEAKSHGLYRVMRILVHSQFFDKVKMTLSEGESEEEEEEEEAYCLTRASRLLLRNEPLSMAPYVRAMLDPNFMDPFHHLSEWLRNKCPSPFVLKHGKTIWEYAGIEPSWNQLFNESMANDARLVTSILVKECRQVFEGLGTMVDVGGGTGGVARTVTDAFPGLKGIVLDLPHVVANLQNSENLRYVGGDMFDSIPHADAVLLKWILHDWSDEACVKLLEKCKEAITPNGGKVIVVEMILDDKKGDHKATETQLFFDALMMTANIGKERSEKEWANLFFAAGFKTYKIHPVLRLRSVIEVFP
>rna-gnl|WGS:QIYW|chr06_14162414_14164175.mrna1
MASANGVGAESSRKELLDAQAHVYNHTFNFINSMSLNCAIQLGIPDIIHKHGKPMTLSQLADALPINKAKSHGLFRVMRILVHSKFFNKDVDEEEAYCLTQASRLLLRDDPISLAPYVISMIDPIMMDPFHHLSEWLQDECLNPVFTKHGKTFWELAGVDQNLNKKFNEAMACDAGFVTSILTTDCRQVFEGLESMVDVGGGTGETAMAKGIADAFPGLKCIVLDLPHVVGGLEGCENLRFFSGDMFESIPNADAVFLKWILHDWSDEECVKILKKCKEAITPNGGKVIIVEMILEDQIEDEKATQTQFFFDVLMMVGLTGKQRSEKEWSQLFSAAGFGHYKMNPAALGLRSVIEVFP
>rna-gnl|WGS:QIYW|chr06_13953023_13953920.mrna1
MSAAARGAMAKALVDTFSGLKCTVLDLPQVVAGLEGSNNLRFVSGDMFQFIPPTDAVFLKRIMHDWSDENCVKILGKCKEAIIPSKNNGGKFVHNMEHRTVKHLIITQVSYEEGS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University