Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Parasponia andersonii
Species name
Parasponia andersonii is a species of eudicot in the family Cannabaceae (hemp family).
Species info
Gene sequence info
Parasponia_andersonii.OMT.fa
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>rna-gnl|WGS:JXTB|PanWU01x14_023020.1
MVQDQDSSELFQAQAHLYKHVLSYMSSMSLKCAVQLGVPDAINNHGQPITLPELVSALQIHPKKTDFVRRIMRLLAHSGFFKTTKLGQNNEGEEEDEVEAYDLTPTSRLLLKNRVPNLSAFVVGLSDPAFVTPAHFLADWLRADDDQVLTAPFDSTFGLNLWDYANKNPEFNDDFNEAMASDSEMMNLVVKHCKPVFEGLCSVVDVGGGTGKIARIITEEFPHLKFTVLDLPHVIANLPETENLKFIEGDMFKHIPPTDAVFLKLILHDWSDEQCLKVLKNCREAIPNNAKGKVIIIDIVLNDINNENDEDDPGLGLTADAKLHYDLMMMACLAGKERSEKEWKKLFLGAGFSHYKIKPIFGLRSLIEVFP
>rna-gnl|WGS:JXTB|PanWU01x14_022990.1
QGALPGLLLFREDEVKNLNFQVILKSLTEWGWPYHWDLIRLFFYQKKIFYFDLLIMAIVTGRDGSNKDWGNFFIEAGFTSFKITPIFSLRTLIEVFP
>rna-gnl|WGS:JXTB|PanWU01x14_118880.1
MASLVESEASLREQAQIWKYLFGFADSMALKCAVELRIPDILHSHPEPITLAQIAAAIPDAPSPDLSYLFRIMRLLVVRRIFTFQRAPDGSEGGGLYGPTNLSRWLLREPTPSDRHHGHHLTLAPMVLQENHPWFLDSWHLLSQTVREGGDCPFEKAYGEMFAFAGKNPEFNKILNEGMACTAKITIRTILSHYGDGLFRGGDDDGSLIRSIVDVGGGTGSVVSEIVKAYPHIRGINFDRPHVIKTAPEYPGVTHVGGDMFQEVPPADAVFTKASTFPAQYRLHTLFA
>rna-gnl|WGS:JXTB|PanWU01x14_118890.1
MGSTCKLTNWVLHDWGDELCVKLLKNCRKAIPEKTGKLIIADIVVEAEGTGPFDDTGVVFDLVLLAHNTGGKERTEKEWKKLLAQAGFPRYKITKIPALTSIIEAYPK
>rna-gnl|WGS:JXTB|PanWU01x14_232300.1
MEKSRSFKSFRHLTNTDLVNEQTSTELLEAQAHIWNHIFAFINSMSLKCAIQLGIPDTIQNHGKPMTISQLVASLPIHQKKASCVYRLMRILVHSGFFALQKVGETDDEQEGYALTDASKLLLKDNPLSVTPFLLAMLDPVLTKPWHFLSTWFQNEDPTPFDTANGMTFWDYGSHEPKLARFFNDAMASDARLVMTVVIDKCKGVFEGLESLVDVGGGTGTVAKAIATAFPQIECTVFDLPHVVADLQGGDNLKFVGGDMFDAVPPAEAVLLKWILHDWTDEESVKILKKCKEAISKSNNRGKVIVIDMKVENDKDEDHESYETQLFFDMLMMALVTGRERSEKEWAKLFQDAGFSDYKITPILGLRSLIEVYP
>rna-gnl|WGS:JXTB|PanWU01x14_271600.1
MHKLSFRHLRAVLGAVKVVEFTNFRQERRFSHFINKDLIIKESSSVELLKAHAFIWNRMFSFINSMSLRCAIQLGIPDAIHNHGKPMNLPQLLAALPIHQTKAPFVRRLMRILVHSGFFTVEKVSEIDVLEEGYILTNASRLLLKDHPLSVAPFVLGILDPIVAKPYHHMSSWFQNDSPTAFHTAYGMNIWDYTCHEPKLAHLFNQCMESDSRLVSSVLMKECKQVFDGIEKFVDVGGGTGTVAKAIADTFPHLECIVLDLPHVVADLEGTKNMTFLGGDMFDALPSADAILLKWILHDWNDEESLKILLRCKEAITSKGNHKKGKVIIIDMVMRNKNESDDDDQSVETQLFFDMHMMVLLTGKQRNEEEWAKLFCDAGFSSYKITPILGLRSLIELYP
>rna-gnl|WGS:JXTB|PanWU01x14_289430.1
MFTLASSQPKWLTKANYNMNKSTPESAYSLTNTTRLLLSEAPAFMKMKPLFLFHLLPEAMAPWHTLSTWLKNGDISAFETAKGRTFWDCLADEPSLSHIFNKAMASDSQLIAKVTLEEYKEVFEGLTSLVDVGGGTGTMAKAVANKFPNVTCTVFDLPHVVSDLQGSSDADLITFIGGNVFSDPIPPADAILLKVYIYMLRCIYYVVLY
>rna-gnl|WGS:JXTB|PanWU01x14_289440.1
LFLHDWDDEDCVTILKRCKEAVLRNGDKGGKVIVMDMVLDNQKIYEELSGIQLCNDVLMMAVSGKERTLTEWEKLFLAAGFTSYNITPILGSARSLIEVYP
>rna-gnl|WGS:JXTB|PanWU01x14_350880.1
MREAQRDQLTWRSKDQEEEYRAKVDIYKYIFGFVEMAVVKCAVELGIADTIESHGRPMTLLEISSALGCAPPTLYRIMRFLVNRRIFKEIRNDASVQGSQACNLYAQTALSRLLVRSGESSMAAFVLMESSPTMLAPWHRLSALAKAEGADSSAPFVAANGKDVWSYAAANPAHSQLINEAMACNARFTVVAMVEGCLDVFDGISTVVDVGGGNGTALLMLVKVCPWIRGINFDLPHVVSVALESDCVEHVGGDMFDSVPKADAAFLMWVLHDWSDDECIQILKRCREAIPEEKGKVIIVESVIEINNYQQKLKEEELKLKDVGLFLDMVMMAHTNRGKERTLEEWVYVLGQAGFTRHNVRPINAVSSVIEAFPA
>rna-gnl|WGS:JXTB|PanWU01x14_350890.1
MEKAQREQLKWKSKEQEEEERAKVDIYKYIFGFVEMAVVKCAIELGIADAIESHGRPMTLLELSSASGCAPSTLYRIMRFLINRRIFKEIRNDASVQGSQACNLYAQTALSRLLLRSGESSMAVFVLMESIPPMLAPWHGLSARVKTEGADSSAPFEAANGKDLWSYAAANPAHSQLFNEAMACNARVTVAAMVEGCPDVFDGIRTLVDVGGGNGTALRTLVKACPWIRGINFDLPHVVSVAIESDGVEHVGGDMFDSVPKADAVFLMSVLHDWADDECIQILKKCREAIPEEKGKVIMVECVIENNEQKPKEEELKLKDVSLFLDMVMIAHTDSGKERTMEEWAYVLGHAGFIRYTVRSINAIYSVIEAFPA
>rna-gnl|WGS:JXTB|PanWU01x14_350940.1
MEGTQRDKLIWRSKEEEAEDKRAKVDIYKYIFGFVEMAVVKCAIELGIADAIESRGHPMTLLELSSALDCALPTLYRIMRFLVNRRIFKEIRDDASVQGSQACNLYAQTALSRLLLRSGESSMAVFVLMESSPPMLAPWHGMSARVKDEGADSSAPFEAANGKDLWSYDAANLAHGQLFNEAMACNASVRRWWKACPWIRGINFDLPHVVSVALESDGVEHVGGDMFDSVPKADAAFLMWVLHDWADDECIQILKKCREAIPEEKGKVIIVESVIEINNDQQKLKEEELKLKDVGLFLDMVMIAHTNKGKERTLEEWAYVLGQAGFIRHTVRSINTVSSVIEAFPA
>rna-gnl|WGS:JXTB|PanWU01x14_352810.1
MEAAGAEAEASLRGQVEIWKYTLSFADSMALKSAVELRIPDIIHSHAGPMTVAQIASAIPDSPSPDLYCLARIMRLLVRRRIFTAQQPSDDGGEALYGPTHSSRWLLSETAAPDQLTLAPMVLMENHPWLMAPWHCFSRCVREGGIAFEKAHGGRHIWDFAAENPEFNKLFNDAMECTARIIMRAILSEYRDGFGGCCLRSLVDVGGGTGGAVSEIVRSHPHIRGINFDLPHVVATAPEYPGCHMSEVTCLKASPLLTQFL
>rna-gnl|WGS:JXTB|PanWU01x14_368500.1
MNLIMAEDEVSSSELLQAQELIWSCSLNFIKPMSLKCAIELGIPDIIHNHGQPITLSELISSLPIHPSKAHCISRLMRILVHFGFFSTHQNVDKIDGQRQEADTYSLTPASRLLLKDGPLRATPFFLVQLNPLLITPWHFLSTWLKNGDPTPFEMVHGRNFWDGVGHDPMVKYLFTEAMATDSHLMAKVIVEECKEVFEGLSSLVDVGGGTGIMAMGIVKAFPNIQCTVLDLPYVVANLKGTNNLNLIEGDMFKKIPSANAVLLKWILHDWSDEEAVNILRKCREAIWSKDRGGKVIIIDMVIDSPTKTDRKSAETQLCFDMLMMVNLTGKERNEKEWGKLFSAAGFSNYKITPIVGLRYLIEVYP
MVQDQDSSELFQAQAHLYKHVLSYMSSMSLKCAVQLGVPDAINNHGQPITLPELVSALQIHPKKTDFVRRIMRLLAHSGFFKTTKLGQNNEGEEEDEVEAYDLTPTSRLLLKNRVPNLSAFVVGLSDPAFVTPAHFLADWLRADDDQVLTAPFDSTFGLNLWDYANKNPEFNDDFNEAMASDSEMMNLVVKHCKPVFEGLCSVVDVGGGTGKIARIITEEFPHLKFTVLDLPHVIANLPETENLKFIEGDMFKHIPPTDAVFLKLILHDWSDEQCLKVLKNCREAIPNNAKGKVIIIDIVLNDINNENDEDDPGLGLTADAKLHYDLMMMACLAGKERSEKEWKKLFLGAGFSHYKIKPIFGLRSLIEVFP
>rna-gnl|WGS:JXTB|PanWU01x14_022990.1
QGALPGLLLFREDEVKNLNFQVILKSLTEWGWPYHWDLIRLFFYQKKIFYFDLLIMAIVTGRDGSNKDWGNFFIEAGFTSFKITPIFSLRTLIEVFP
>rna-gnl|WGS:JXTB|PanWU01x14_118880.1
MASLVESEASLREQAQIWKYLFGFADSMALKCAVELRIPDILHSHPEPITLAQIAAAIPDAPSPDLSYLFRIMRLLVVRRIFTFQRAPDGSEGGGLYGPTNLSRWLLREPTPSDRHHGHHLTLAPMVLQENHPWFLDSWHLLSQTVREGGDCPFEKAYGEMFAFAGKNPEFNKILNEGMACTAKITIRTILSHYGDGLFRGGDDDGSLIRSIVDVGGGTGSVVSEIVKAYPHIRGINFDRPHVIKTAPEYPGVTHVGGDMFQEVPPADAVFTKASTFPAQYRLHTLFA
>rna-gnl|WGS:JXTB|PanWU01x14_118890.1
MGSTCKLTNWVLHDWGDELCVKLLKNCRKAIPEKTGKLIIADIVVEAEGTGPFDDTGVVFDLVLLAHNTGGKERTEKEWKKLLAQAGFPRYKITKIPALTSIIEAYPK
>rna-gnl|WGS:JXTB|PanWU01x14_232300.1
MEKSRSFKSFRHLTNTDLVNEQTSTELLEAQAHIWNHIFAFINSMSLKCAIQLGIPDTIQNHGKPMTISQLVASLPIHQKKASCVYRLMRILVHSGFFALQKVGETDDEQEGYALTDASKLLLKDNPLSVTPFLLAMLDPVLTKPWHFLSTWFQNEDPTPFDTANGMTFWDYGSHEPKLARFFNDAMASDARLVMTVVIDKCKGVFEGLESLVDVGGGTGTVAKAIATAFPQIECTVFDLPHVVADLQGGDNLKFVGGDMFDAVPPAEAVLLKWILHDWTDEESVKILKKCKEAISKSNNRGKVIVIDMKVENDKDEDHESYETQLFFDMLMMALVTGRERSEKEWAKLFQDAGFSDYKITPILGLRSLIEVYP
>rna-gnl|WGS:JXTB|PanWU01x14_271600.1
MHKLSFRHLRAVLGAVKVVEFTNFRQERRFSHFINKDLIIKESSSVELLKAHAFIWNRMFSFINSMSLRCAIQLGIPDAIHNHGKPMNLPQLLAALPIHQTKAPFVRRLMRILVHSGFFTVEKVSEIDVLEEGYILTNASRLLLKDHPLSVAPFVLGILDPIVAKPYHHMSSWFQNDSPTAFHTAYGMNIWDYTCHEPKLAHLFNQCMESDSRLVSSVLMKECKQVFDGIEKFVDVGGGTGTVAKAIADTFPHLECIVLDLPHVVADLEGTKNMTFLGGDMFDALPSADAILLKWILHDWNDEESLKILLRCKEAITSKGNHKKGKVIIIDMVMRNKNESDDDDQSVETQLFFDMHMMVLLTGKQRNEEEWAKLFCDAGFSSYKITPILGLRSLIELYP
>rna-gnl|WGS:JXTB|PanWU01x14_289430.1
MFTLASSQPKWLTKANYNMNKSTPESAYSLTNTTRLLLSEAPAFMKMKPLFLFHLLPEAMAPWHTLSTWLKNGDISAFETAKGRTFWDCLADEPSLSHIFNKAMASDSQLIAKVTLEEYKEVFEGLTSLVDVGGGTGTMAKAVANKFPNVTCTVFDLPHVVSDLQGSSDADLITFIGGNVFSDPIPPADAILLKVYIYMLRCIYYVVLY
>rna-gnl|WGS:JXTB|PanWU01x14_289440.1
LFLHDWDDEDCVTILKRCKEAVLRNGDKGGKVIVMDMVLDNQKIYEELSGIQLCNDVLMMAVSGKERTLTEWEKLFLAAGFTSYNITPILGSARSLIEVYP
>rna-gnl|WGS:JXTB|PanWU01x14_350880.1
MREAQRDQLTWRSKDQEEEYRAKVDIYKYIFGFVEMAVVKCAVELGIADTIESHGRPMTLLEISSALGCAPPTLYRIMRFLVNRRIFKEIRNDASVQGSQACNLYAQTALSRLLVRSGESSMAAFVLMESSPTMLAPWHRLSALAKAEGADSSAPFVAANGKDVWSYAAANPAHSQLINEAMACNARFTVVAMVEGCLDVFDGISTVVDVGGGNGTALLMLVKVCPWIRGINFDLPHVVSVALESDCVEHVGGDMFDSVPKADAAFLMWVLHDWSDDECIQILKRCREAIPEEKGKVIIVESVIEINNYQQKLKEEELKLKDVGLFLDMVMMAHTNRGKERTLEEWVYVLGQAGFTRHNVRPINAVSSVIEAFPA
>rna-gnl|WGS:JXTB|PanWU01x14_350890.1
MEKAQREQLKWKSKEQEEEERAKVDIYKYIFGFVEMAVVKCAIELGIADAIESHGRPMTLLELSSASGCAPSTLYRIMRFLINRRIFKEIRNDASVQGSQACNLYAQTALSRLLLRSGESSMAVFVLMESIPPMLAPWHGLSARVKTEGADSSAPFEAANGKDLWSYAAANPAHSQLFNEAMACNARVTVAAMVEGCPDVFDGIRTLVDVGGGNGTALRTLVKACPWIRGINFDLPHVVSVAIESDGVEHVGGDMFDSVPKADAVFLMSVLHDWADDECIQILKKCREAIPEEKGKVIMVECVIENNEQKPKEEELKLKDVSLFLDMVMIAHTDSGKERTMEEWAYVLGHAGFIRYTVRSINAIYSVIEAFPA
>rna-gnl|WGS:JXTB|PanWU01x14_350940.1
MEGTQRDKLIWRSKEEEAEDKRAKVDIYKYIFGFVEMAVVKCAIELGIADAIESRGHPMTLLELSSALDCALPTLYRIMRFLVNRRIFKEIRDDASVQGSQACNLYAQTALSRLLLRSGESSMAVFVLMESSPPMLAPWHGMSARVKDEGADSSAPFEAANGKDLWSYDAANLAHGQLFNEAMACNASVRRWWKACPWIRGINFDLPHVVSVALESDGVEHVGGDMFDSVPKADAAFLMWVLHDWADDECIQILKKCREAIPEEKGKVIIVESVIEINNDQQKLKEEELKLKDVGLFLDMVMIAHTNKGKERTLEEWAYVLGQAGFIRHTVRSINTVSSVIEAFPA
>rna-gnl|WGS:JXTB|PanWU01x14_352810.1
MEAAGAEAEASLRGQVEIWKYTLSFADSMALKSAVELRIPDIIHSHAGPMTVAQIASAIPDSPSPDLYCLARIMRLLVRRRIFTAQQPSDDGGEALYGPTHSSRWLLSETAAPDQLTLAPMVLMENHPWLMAPWHCFSRCVREGGIAFEKAHGGRHIWDFAAENPEFNKLFNDAMECTARIIMRAILSEYRDGFGGCCLRSLVDVGGGTGGAVSEIVRSHPHIRGINFDLPHVVATAPEYPGCHMSEVTCLKASPLLTQFL
>rna-gnl|WGS:JXTB|PanWU01x14_368500.1
MNLIMAEDEVSSSELLQAQELIWSCSLNFIKPMSLKCAIELGIPDIIHNHGQPITLSELISSLPIHPSKAHCISRLMRILVHFGFFSTHQNVDKIDGQRQEADTYSLTPASRLLLKDGPLRATPFFLVQLNPLLITPWHFLSTWLKNGDPTPFEMVHGRNFWDGVGHDPMVKYLFTEAMATDSHLMAKVIVEECKEVFEGLSSLVDVGGGTGIMAMGIVKAFPNIQCTVLDLPYVVANLKGTNNLNLIEGDMFKKIPSANAVLLKWILHDWSDEEAVNILRKCREAIWSKDRGGKVIIIDMVIDSPTKTDRKSAETQLCFDMLMMVNLTGKERNEKEWGKLFSAAGFSNYKITPIVGLRYLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University