Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Parasponia andersonii
Species name
Parasponia andersonii is a species of eudicot in the family Cannabaceae (hemp family).
Species info
Gene sequence info
Parasponia_andersonii.4CL.fa
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>rna-gnl|WGS:JXTB|PanWU01x14_026900.1
MSVETQKPEISPNISTPQTQTSTTSTANNIDHHVFKSKLPEIPISKNLPLHAYCFERMSELADRPCLIVGSTGRTYSFAETRLIAQKTGAGLSGLGIKRGDVIMILLQNCAEFVFAFMGASMIGAVTTTANPFYTSAEVFKQFNASKAKLIITQSQYVDKLREPAGDQYPKLGEDFSVFTIDDPPENCLHFSVLSEANENDIPEVVIDPDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKTEDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMPKFEIGTLLELIQRHCVSVAAVVPPLVLALAKNPKVAEFDLSSIRVVLSGAAPLGKELEDALRSRVPQAILGQGYGMTEAGPVLSMCLAFARQPLPSKSGSCGTVVRNAELKVVDPLTGCSFGRNQPGEICIRGAQIMKGYLNDPEATAATIDVEGWLHTGDIGYVDDDDEIFIVDRVKELIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDDVAGEVPVAFVVRSNGFDLTEEAVKEFIAKQVVFYKKLHKVFFVHAIPKSPSGKILRKDLRAKLCHS
>rna-gnl|WGS:JXTB|PanWU01x14_109140.1
MEKSGYGRDGIFRSLRPPLVLPKDPNLSMVSFLFRNASSYPRKPALIDADTNETLSFSEFKSMVIKVSHGYLHLGIQKNDVVLIFAPNSIQFPVCFLGITATGAIATTSNPLCTVSELSKQVKDSSPKLIVTVPELWDKVKGFNLPTVFLGPKHSSPPPLKSSSKVITFHDLVGLSRSVSDFPLVSIKQTDTAVLLYSSGTTGTSKGVVLTHKNFIAASLMVTMDQEQAGELHNVFLCFLPMFHVFGLAVITYAQLQRGNAVVSMARFDLEKILNAVEKYKVTHLWVVPPVILALAKNSVVKKYNLSSLKHIGSGAAPLGKDLMEECAKIVPQGVVAQGYGMTETCGIVSVEDTRGGKRHTGSAGMLASGVEAQIVSVDTLKPLPPKQLGEIWVRGPNMMQGYFNNPQATKLTIDKKGWVHTGDLGYFDEDGYLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDVEAGEVPVAYIVRSPNSSLTEVDVKKFIADQVAPFKRLRKVTFINSVPKSASGKILRRELIQKVRSKV
>rna-gnl|WGS:JXTB|PanWU01x14_178310.1
MELPKQEDNHHQEEFIFRSKLPDIYIPNHLPLHSYCFENIAQFKDRPCLINGASGEIISYADVELTARRVAAGLDKIGIKQGDVIMLLLQNSPEFVYAFLGASYIGAISTTANPFYTPAEVAKQAAASKTRLVVTLSAYVDKVKDFAGGESGIKVVCVDAPPPESGILHFSELTQADEGEIPAVKIHPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFHQNDVILCVLPLFHIYSLNSILLCGLRVGAAILIMQKFEINKLLELVEKFKVTIAPFVPPIVLSIAKSPELHRYDLSSIRTVMSGGAPMGKDLEEAVKEKLPHAKLGQGYGMTEAGPVLSMCLAFAKEPFAIKSGACGTVVRNAEMKIVDPDTGASLPRNQAGEICIRGKQIMKGYINDPEATKGTVDEGGWLHTGDIGFIDDDDELFIVDRLKELIKFKGFQVAPAELEAMLIAHPYISDAAVVPMKDEAAGEVPVAYVVRSNGSKITEEEIKQYISKQVVFYKRISKVFFIEKIPKSPSGKILRKDLRARLVAE
>rna-gnl|WGS:JXTB|PanWU01x14_207130.1
MAVTETKQQDIIYRSKLPDIYIPKDLPLHTYCLGNKSRQGSRPCIIYGPTGKIYTYDDVELNARKVASGLDKLGIKQGDVIMVLLPNSPEYVFAFLGASYRGAMTTAANPFFTSAEILKQAKASKAKLVITQASYYEKVKDLNSADQEVKLMCVDSPVPEGWFHFSELAEADENDLPEVDIGPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYYGKDDVVLCVLPLFHIYSLNSVMLCSLRAGAAILIMPKFEIGSLLELIQRYKVSVAPVVPPIVLAIAKYPDLDKYDLSSLRVLKCGGAPLGKELEDTVRAKFPSVTLGQGYGMTEAGPVLTMSLAFAKEPLEVKPGACGTVVRNAELKIVDPETGSSLPRNQPGEICIRGDQIMKGYLNDPESTKNTIDKEGWLHTGDIGLVDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPHISDAAVVPMNDEAAGEVPVAFVVRSNNSQITGDEIKQFISKQVVFYKRINRVFFIEAIPKSPSGKILRKDLRAKLAAGLV
>rna-gnl|WGS:JXTB|PanWU01x14_222160.1
MATSPKNDHEHIFCSRYPPVQVPDNVTLPEFVLQGGELYADKVAFVEAVTGKAYTHGEVVRNTRRFATALRSLGLRKGHVVVVVLPNVVEYAVVALGIMAAGGVFSGANPTATPTEIKKQVEDSGAKLIVTNGSCFEKVKGLEVPVIAVDEEAVVEGAINWHKLLEAANRAGTSHNMEEVHQTDLCALPFSSGTTGVSKGVMLTHRNLVANLCSTLFGIKPEMVGRVTVLGLMPFFHIYGITGICCATLRNKGKVVVMERYELRTFLRALVSQEVTFAPVVPPIISDLVKKPAVDEFDLSKIKLQAVMSAAAPLAPELLRAFETKFPNVHVQEAYGLTEHSCITLSYGDNGYSRAKKNSVGFILPNLEVKFLDPETGRSLPKNTPGEICVRSQCVMKGYYNNKEETERTIDKDGWLHTGDIGYIDDDGDVFIVDRIKEMIKYKGFQVAPAELEAILLTHASVEDAAVFSLPDEEAGEIPAACVVLAPDAKETEEEIISYVASNVARYKKVRAVHFVDSIPKSPSGKIMRRLLKDAWVKNVKNISVKRY
>rna-gnl|WGS:JXTB|PanWU01x14_233230.1
MAKSFNPETQTYISPRPPVDFPTDPNLSLTSFLFQSSSPHPHRTALIDADSGQTLSFLQLKNLVCNLSHALVRLNVRKNDVVLIFAQNSIQFPVCFLSIAALGAITTTCNPSYTFSELSKQVQDCNPKLVITVPDLWETVVKLDLPAIILGSSSPPPPNSESQIWHFSDLVENSDRFPELPEDSNVAQADVAALLYSSGTTGTNKGVVLTHKNFITTSLMVPSDQDRYGEPQNVCLCFLPMFHIFGLSVITYSQLRRGNSVVSMGKFEFENALRVVEKYRVTHMFVVPPVMIALAKQSVVKKYDLSSLKMVLSGAAPLGKDVMEKCAENVNGAAIIQGYGMTETCGIVSLENSREGSRFSGSTGILAPGIESKIVSVETLKPLPPNQLGEIWLRGPNVMRGYLNNPQATKSTIDEQGWMRTGDLGYFDEEGQLFVVDRLKELIKCYGFQVAPAELEGLLLSHSEILDAVVIPFPDEKAGEVPIAYVVRAQNSSLTQEDVQRFIEKQVAPFKRLRRVTFVSSVPKSASGKILRRELVQKVRSKI
MSVETQKPEISPNISTPQTQTSTTSTANNIDHHVFKSKLPEIPISKNLPLHAYCFERMSELADRPCLIVGSTGRTYSFAETRLIAQKTGAGLSGLGIKRGDVIMILLQNCAEFVFAFMGASMIGAVTTTANPFYTSAEVFKQFNASKAKLIITQSQYVDKLREPAGDQYPKLGEDFSVFTIDDPPENCLHFSVLSEANENDIPEVVIDPDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKTEDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMPKFEIGTLLELIQRHCVSVAAVVPPLVLALAKNPKVAEFDLSSIRVVLSGAAPLGKELEDALRSRVPQAILGQGYGMTEAGPVLSMCLAFARQPLPSKSGSCGTVVRNAELKVVDPLTGCSFGRNQPGEICIRGAQIMKGYLNDPEATAATIDVEGWLHTGDIGYVDDDDEIFIVDRVKELIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDDVAGEVPVAFVVRSNGFDLTEEAVKEFIAKQVVFYKKLHKVFFVHAIPKSPSGKILRKDLRAKLCHS
>rna-gnl|WGS:JXTB|PanWU01x14_109140.1
MEKSGYGRDGIFRSLRPPLVLPKDPNLSMVSFLFRNASSYPRKPALIDADTNETLSFSEFKSMVIKVSHGYLHLGIQKNDVVLIFAPNSIQFPVCFLGITATGAIATTSNPLCTVSELSKQVKDSSPKLIVTVPELWDKVKGFNLPTVFLGPKHSSPPPLKSSSKVITFHDLVGLSRSVSDFPLVSIKQTDTAVLLYSSGTTGTSKGVVLTHKNFIAASLMVTMDQEQAGELHNVFLCFLPMFHVFGLAVITYAQLQRGNAVVSMARFDLEKILNAVEKYKVTHLWVVPPVILALAKNSVVKKYNLSSLKHIGSGAAPLGKDLMEECAKIVPQGVVAQGYGMTETCGIVSVEDTRGGKRHTGSAGMLASGVEAQIVSVDTLKPLPPKQLGEIWVRGPNMMQGYFNNPQATKLTIDKKGWVHTGDLGYFDEDGYLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDVEAGEVPVAYIVRSPNSSLTEVDVKKFIADQVAPFKRLRKVTFINSVPKSASGKILRRELIQKVRSKV
>rna-gnl|WGS:JXTB|PanWU01x14_178310.1
MELPKQEDNHHQEEFIFRSKLPDIYIPNHLPLHSYCFENIAQFKDRPCLINGASGEIISYADVELTARRVAAGLDKIGIKQGDVIMLLLQNSPEFVYAFLGASYIGAISTTANPFYTPAEVAKQAAASKTRLVVTLSAYVDKVKDFAGGESGIKVVCVDAPPPESGILHFSELTQADEGEIPAVKIHPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFHQNDVILCVLPLFHIYSLNSILLCGLRVGAAILIMQKFEINKLLELVEKFKVTIAPFVPPIVLSIAKSPELHRYDLSSIRTVMSGGAPMGKDLEEAVKEKLPHAKLGQGYGMTEAGPVLSMCLAFAKEPFAIKSGACGTVVRNAEMKIVDPDTGASLPRNQAGEICIRGKQIMKGYINDPEATKGTVDEGGWLHTGDIGFIDDDDELFIVDRLKELIKFKGFQVAPAELEAMLIAHPYISDAAVVPMKDEAAGEVPVAYVVRSNGSKITEEEIKQYISKQVVFYKRISKVFFIEKIPKSPSGKILRKDLRARLVAE
>rna-gnl|WGS:JXTB|PanWU01x14_207130.1
MAVTETKQQDIIYRSKLPDIYIPKDLPLHTYCLGNKSRQGSRPCIIYGPTGKIYTYDDVELNARKVASGLDKLGIKQGDVIMVLLPNSPEYVFAFLGASYRGAMTTAANPFFTSAEILKQAKASKAKLVITQASYYEKVKDLNSADQEVKLMCVDSPVPEGWFHFSELAEADENDLPEVDIGPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYYGKDDVVLCVLPLFHIYSLNSVMLCSLRAGAAILIMPKFEIGSLLELIQRYKVSVAPVVPPIVLAIAKYPDLDKYDLSSLRVLKCGGAPLGKELEDTVRAKFPSVTLGQGYGMTEAGPVLTMSLAFAKEPLEVKPGACGTVVRNAELKIVDPETGSSLPRNQPGEICIRGDQIMKGYLNDPESTKNTIDKEGWLHTGDIGLVDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPHISDAAVVPMNDEAAGEVPVAFVVRSNNSQITGDEIKQFISKQVVFYKRINRVFFIEAIPKSPSGKILRKDLRAKLAAGLV
>rna-gnl|WGS:JXTB|PanWU01x14_222160.1
MATSPKNDHEHIFCSRYPPVQVPDNVTLPEFVLQGGELYADKVAFVEAVTGKAYTHGEVVRNTRRFATALRSLGLRKGHVVVVVLPNVVEYAVVALGIMAAGGVFSGANPTATPTEIKKQVEDSGAKLIVTNGSCFEKVKGLEVPVIAVDEEAVVEGAINWHKLLEAANRAGTSHNMEEVHQTDLCALPFSSGTTGVSKGVMLTHRNLVANLCSTLFGIKPEMVGRVTVLGLMPFFHIYGITGICCATLRNKGKVVVMERYELRTFLRALVSQEVTFAPVVPPIISDLVKKPAVDEFDLSKIKLQAVMSAAAPLAPELLRAFETKFPNVHVQEAYGLTEHSCITLSYGDNGYSRAKKNSVGFILPNLEVKFLDPETGRSLPKNTPGEICVRSQCVMKGYYNNKEETERTIDKDGWLHTGDIGYIDDDGDVFIVDRIKEMIKYKGFQVAPAELEAILLTHASVEDAAVFSLPDEEAGEIPAACVVLAPDAKETEEEIISYVASNVARYKKVRAVHFVDSIPKSPSGKIMRRLLKDAWVKNVKNISVKRY
>rna-gnl|WGS:JXTB|PanWU01x14_233230.1
MAKSFNPETQTYISPRPPVDFPTDPNLSLTSFLFQSSSPHPHRTALIDADSGQTLSFLQLKNLVCNLSHALVRLNVRKNDVVLIFAQNSIQFPVCFLSIAALGAITTTCNPSYTFSELSKQVQDCNPKLVITVPDLWETVVKLDLPAIILGSSSPPPPNSESQIWHFSDLVENSDRFPELPEDSNVAQADVAALLYSSGTTGTNKGVVLTHKNFITTSLMVPSDQDRYGEPQNVCLCFLPMFHIFGLSVITYSQLRRGNSVVSMGKFEFENALRVVEKYRVTHMFVVPPVMIALAKQSVVKKYDLSSLKMVLSGAAPLGKDVMEKCAENVNGAAIIQGYGMTETCGIVSLENSREGSRFSGSTGILAPGIESKIVSVETLKPLPPNQLGEIWLRGPNVMRGYLNNPQATKSTIDEQGWMRTGDLGYFDEEGQLFVVDRLKELIKCYGFQVAPAELEGLLLSHSEILDAVVIPFPDEKAGEVPIAYVVRAQNSSLTQEDVQRFIEKQVAPFKRLRRVTFVSSVPKSASGKILRRELVQKVRSKI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University