Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Panax ginseng
Species name
Asiatic ginseng (Panax ginseng) is a species of eudicot in the family Araliaceae (ginseng family).
Species info
Gene sequence info
Panax_ginseng.COMT.fa
Download
>Pg_S7666.1
MASKDEDQEYFLKAIQLADSSVIHGVLRALLELNVFDIMMSKAGLDGYLSPVEIESYLPTQNPHAPAILDRLLRLLATHSILNCTLVKTTPPTRTYGLTTLSKYFIRNQDGPSVAHLFLFGHSKAIADSWYCLKDTILEGGIPFNKAHEGMHIFEYLEKDRKLNQIFTEGMGKSTTSAMTKILEMYNGFEEVKEVVHRVLHDWKDEECLMILKNCYEALPESGKVVVIDMVLVDFPENDLVSKCVAQLDIGMLMVTHGGKERTEGEFGALAIAAGFAAYKFICRADLFGVIELYKKM
>Pg_S4251.2
MASNDQEEFLKAVQLADSHAIHGVLSALVELNVIDIMMAKAGLDGYLSAVEIASYLPTQNPQAPAILDRLLRLLATHSILKCTLVKTNTILEGGIPFNKAHEGMHIFEYLEKDRKLNQIFTEAMEKYTTSDMAKILEMYNGFEEVKEVVDVGGLLGEALGTIISKYPFIKGVNFDLPHVLKHAPALPGVEHVGGDMFEGVPKGQVILLKRVLHDWKDEECLKILKNCYEALPDSGKVVVIDMVLVDFPENDIVSKCVAQLDIAMLMITHGGKERTEGEFGALAIAAGFAAYKFICREDLLGVIELYKKI
>Pg_S4251.1
MHIFEYLEKDRKLNQIFTEAMCMSTMNAMAKILEMYNGFEEVKEVVDVGGSLGETLGTIISKYPFIKGVNFDLPHVLKHAPALPGVEHIGGDMFEAVPKGQLDK
>Pg_S4798.9
MHIFEYLEKERKLNQIFTEGMGKSTTSAMTKILEMYNGFEEVKEVVHVGGSLGETLGTIISKYPFIKGVNFDLPHVLKHAPALPGVEHVGGDMFEAVPKGQVILLKCVAQLDIGMLMLSHGGRERTEGEFGALARAAGFAAYKFMCHADLFGVFELYKKM
>Pg_S0219.8
MDTRAEIKVNPVNEVDQEEEACLFAMQLASASVLPMVLKSAIELDLLETIAKAGPGAYVSPSELASQLPSHNPGAPVMLDRILRLLTSYSVLNCKLKELPGGGGIERLYGLAPVCKFLTKNADGVSMAPLLLMNQDKILMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSNHSTITMKKILETYNGFDGLTSVVDVGGGTGATLHMILSKYPSIKGINFDLPHVVEDAPSYPGVEHVGGDMFVSVPKGDAVFMKWICHDWSDEHCLKLLKNCYEALPNNGKVIIAECILPEAPDTKLATKNVIHIDFIMLAHNPGGKERTEKEFEALAKGAGFKVFNKACCAFNTWVMEFCK
>Pg_S8510.3
MSNGDDELSRAMQLNAGSVLPMVLRAAIELDLFEIMAKSSSTGTQKLWSSYEIASHLPTKNPDAPVMLERILRFLASESILTCTIITDENGQNHKPSYGLAPICKYYVRDQDGISLAPSLLLLQDKVVLDSWYHLKDAIIEGGIPFNKAHGMHAFEYPAIDNRFNEVFNKAMYNTTTVIMKKVLETYNGFEDIQEVVDVGGGFGQTLATIISKYPHIKGINFDLPHVIEDASPIAGVMHVGGDMFESVPKGEAVFLKWILHDWGDEHCLRLLNNCWNALPDSGKVIVVESILPEYSNGDFKSTIVSSHGDMIMLTLNPGGKERTEREFEALAVGAGFAAFKVICHASAFAVIEFHKKI
>Pg_S4531.4
MQTKMSNGDDELSRAMQLNAGSVLPMVLRAAIELDLFEIMAKSSSTGAQKLWSSYEIASHLPTKNPDAPVMLERILRFLASESILTCTIITDENGQDHKPAYGLAPICKYYVRDQDGISLAPSLLLLQDKVVLDSWYHLKDAIIEGGIPFNKAHGMHAFEYPAIDNRFNEVFNKAMYNTTTLIMKKVLESYNGFEDIQEVVDVGGGFGQTLATIISKYPHIKGINFDLPHVIKDASPIAGVMHVGGDMFESVPKGEAIFLKWILHDWGDEHCLRLLNNCWNALPDSGKVIVVESILPEYSNVDFKSTIVGSHGDMIMLTLNPGGKERTEREFEALAVGAGFAAFKVICHASAFAVIEFHKKI
>Pg_S2438.5
MDSRAEIKVNPVNEVDQEEEACLFAMQLASASVLPMVLKSAIELDLLETIAKAGPGAYVSPSELASQLPSHNPGAPVMLDRILRLLTSYSVLNCKLKELPGGGGIERLYGLAPVCKFLTKNADGVSMAPLLLMNQDKILMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTITMKKILETYNGFDGLTSVVDVGGGTGATLHMILSKYPSIKGINFDLPHVVEDSPSYPGVEHVGGDMFVSVPKGDAVFMKWICHDWSDEHCLKLLKNCYEALPNNGKVIIAECILPEAPDTKLATKNVIHIDFIMLAHNPGGKERTEKEFEALAKGAGFKIFNKACCAFNTWVMEFCK
>Pg_S8134.2
MHIFEYLEKDRKLNQIFTEGMGKSTTSEMTKILEKYKGFEEVKEVVDVGGSHGETLGTIISKYPFIKGVNFDLPHVIKHAPALPGVEHVGGDMFEAVPKGQVILLKRVLHDWKDEECLKILKNCYEALPESGKVVVMDMVLVDFPENDIVSKCVAQVDITMLMITHGGKERTEGEFGALAIAAGFAAYKFICRADLFGVIELYKKCEFLNMHFYE
>Pg_S4189.1
MVAVCGPYHRTTASAYSLLAVVLYHTGDFNQATIYQQKALDINERELGLDHPDTMKSYGDLSVFYYRLQHIELALKFCLKDTILEGGIPFNKAHEGMHIFEYLEKDRKLNQIFTEGMGKSTSSAMTKILKMYNGFEEVKEVVDVGGSHGETLGTIISKYPFIKGVNFDLPHVLKHAPALPGVEHVGGDMFEVVPKGQVILLKRVLHDWKDEECLKILKNCYEALPESGKVVVIDMVLVDFPENDIVSKCVAQLDIAMLMVTHGGKERTEGEFGALAIAAGFAAYKFICRADLFGVIELYKKM
>Pg_S6095.5
MGSKTDMKLEEEEEEEACLFAMQLASASVLPMVLKSAIELDLLEKIAKAGPAAYVSHSDLASQLPAHHPGSAVMLDRILRLLTSYSVLICKLRELPDGGVERLYGLAPLCKFLTRNSDGVSMHGTSFAHEPR
>Pg_S2552.2
MASNDQEEFLKAVQFADSQAIHGVLSALFELNVFDIMMAKAGLDGYLSAVEIVSYLPTQNPQAPAILDRLLRLLATHSILKCTLVKTNGPSVAHLFLFGHSKAIADSWYCLKDTILEGGIPFNKAHEGMHIFEYLEKDRKLNQIFTEGMGKSTTSAMTKILEMYNGFEEVKEVVDVGGSHGETLGTIISKYPFIKGVNFDLPHVLKYAPALPGVEHVGGDMFEAVPKGQVILLKRVLHDWKDEECLKILKNCYEALPESGKVVVIDMVLVDFPENDIVSKCVAQLDIAMLMVTHGGKERTEGEFGALAIAAGFAAYKFICRADLFGVIELYKKNVNFSTFL
>Pg_S4267.1
MHIFEYLEKDRKLNQIFTEAMCMSTMNAMAKILEMYNGFEEVKEVIDVGGSLGETLATIISKYPFIKGVNFDLPHVLKHAPPALPGVEHIGGDMFEAVPRGQVILLKRVLHDWKDEECLKILKNCYEALPESGKVVVIDMVLRDFPENDLISKCVAQLDIGMLMLSHGGRERTEGEFGALARAAGFAAYKFMCHADLFGVFELYKKM
>Pg_S4267.2
MYLLFILAFHAKEKVIDRSTMASKDEDQEYFLKAVQLADSSVIHGVLRALVELNVFDIMMAKAGLDGYLSAVEIASYLPTQNPQAPAILDRMLRLLATHSILNCTLAKTSTTNHHDHDDDDDPPPPTRTYGLTPMSKYFVRDQGGPSVAQMLS
MASKDEDQEYFLKAIQLADSSVIHGVLRALLELNVFDIMMSKAGLDGYLSPVEIESYLPTQNPHAPAILDRLLRLLATHSILNCTLVKTTPPTRTYGLTTLSKYFIRNQDGPSVAHLFLFGHSKAIADSWYCLKDTILEGGIPFNKAHEGMHIFEYLEKDRKLNQIFTEGMGKSTTSAMTKILEMYNGFEEVKEVVHRVLHDWKDEECLMILKNCYEALPESGKVVVIDMVLVDFPENDLVSKCVAQLDIGMLMVTHGGKERTEGEFGALAIAAGFAAYKFICRADLFGVIELYKKM
>Pg_S4251.2
MASNDQEEFLKAVQLADSHAIHGVLSALVELNVIDIMMAKAGLDGYLSAVEIASYLPTQNPQAPAILDRLLRLLATHSILKCTLVKTNTILEGGIPFNKAHEGMHIFEYLEKDRKLNQIFTEAMEKYTTSDMAKILEMYNGFEEVKEVVDVGGLLGEALGTIISKYPFIKGVNFDLPHVLKHAPALPGVEHVGGDMFEGVPKGQVILLKRVLHDWKDEECLKILKNCYEALPDSGKVVVIDMVLVDFPENDIVSKCVAQLDIAMLMITHGGKERTEGEFGALAIAAGFAAYKFICREDLLGVIELYKKI
>Pg_S4251.1
MHIFEYLEKDRKLNQIFTEAMCMSTMNAMAKILEMYNGFEEVKEVVDVGGSLGETLGTIISKYPFIKGVNFDLPHVLKHAPALPGVEHIGGDMFEAVPKGQLDK
>Pg_S4798.9
MHIFEYLEKERKLNQIFTEGMGKSTTSAMTKILEMYNGFEEVKEVVHVGGSLGETLGTIISKYPFIKGVNFDLPHVLKHAPALPGVEHVGGDMFEAVPKGQVILLKCVAQLDIGMLMLSHGGRERTEGEFGALARAAGFAAYKFMCHADLFGVFELYKKM
>Pg_S0219.8
MDTRAEIKVNPVNEVDQEEEACLFAMQLASASVLPMVLKSAIELDLLETIAKAGPGAYVSPSELASQLPSHNPGAPVMLDRILRLLTSYSVLNCKLKELPGGGGIERLYGLAPVCKFLTKNADGVSMAPLLLMNQDKILMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSNHSTITMKKILETYNGFDGLTSVVDVGGGTGATLHMILSKYPSIKGINFDLPHVVEDAPSYPGVEHVGGDMFVSVPKGDAVFMKWICHDWSDEHCLKLLKNCYEALPNNGKVIIAECILPEAPDTKLATKNVIHIDFIMLAHNPGGKERTEKEFEALAKGAGFKVFNKACCAFNTWVMEFCK
>Pg_S8510.3
MSNGDDELSRAMQLNAGSVLPMVLRAAIELDLFEIMAKSSSTGTQKLWSSYEIASHLPTKNPDAPVMLERILRFLASESILTCTIITDENGQNHKPSYGLAPICKYYVRDQDGISLAPSLLLLQDKVVLDSWYHLKDAIIEGGIPFNKAHGMHAFEYPAIDNRFNEVFNKAMYNTTTVIMKKVLETYNGFEDIQEVVDVGGGFGQTLATIISKYPHIKGINFDLPHVIEDASPIAGVMHVGGDMFESVPKGEAVFLKWILHDWGDEHCLRLLNNCWNALPDSGKVIVVESILPEYSNGDFKSTIVSSHGDMIMLTLNPGGKERTEREFEALAVGAGFAAFKVICHASAFAVIEFHKKI
>Pg_S4531.4
MQTKMSNGDDELSRAMQLNAGSVLPMVLRAAIELDLFEIMAKSSSTGAQKLWSSYEIASHLPTKNPDAPVMLERILRFLASESILTCTIITDENGQDHKPAYGLAPICKYYVRDQDGISLAPSLLLLQDKVVLDSWYHLKDAIIEGGIPFNKAHGMHAFEYPAIDNRFNEVFNKAMYNTTTLIMKKVLESYNGFEDIQEVVDVGGGFGQTLATIISKYPHIKGINFDLPHVIKDASPIAGVMHVGGDMFESVPKGEAIFLKWILHDWGDEHCLRLLNNCWNALPDSGKVIVVESILPEYSNVDFKSTIVGSHGDMIMLTLNPGGKERTEREFEALAVGAGFAAFKVICHASAFAVIEFHKKI
>Pg_S2438.5
MDSRAEIKVNPVNEVDQEEEACLFAMQLASASVLPMVLKSAIELDLLETIAKAGPGAYVSPSELASQLPSHNPGAPVMLDRILRLLTSYSVLNCKLKELPGGGGIERLYGLAPVCKFLTKNADGVSMAPLLLMNQDKILMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTITMKKILETYNGFDGLTSVVDVGGGTGATLHMILSKYPSIKGINFDLPHVVEDSPSYPGVEHVGGDMFVSVPKGDAVFMKWICHDWSDEHCLKLLKNCYEALPNNGKVIIAECILPEAPDTKLATKNVIHIDFIMLAHNPGGKERTEKEFEALAKGAGFKIFNKACCAFNTWVMEFCK
>Pg_S8134.2
MHIFEYLEKDRKLNQIFTEGMGKSTTSEMTKILEKYKGFEEVKEVVDVGGSHGETLGTIISKYPFIKGVNFDLPHVIKHAPALPGVEHVGGDMFEAVPKGQVILLKRVLHDWKDEECLKILKNCYEALPESGKVVVMDMVLVDFPENDIVSKCVAQVDITMLMITHGGKERTEGEFGALAIAAGFAAYKFICRADLFGVIELYKKCEFLNMHFYE
>Pg_S4189.1
MVAVCGPYHRTTASAYSLLAVVLYHTGDFNQATIYQQKALDINERELGLDHPDTMKSYGDLSVFYYRLQHIELALKFCLKDTILEGGIPFNKAHEGMHIFEYLEKDRKLNQIFTEGMGKSTSSAMTKILKMYNGFEEVKEVVDVGGSHGETLGTIISKYPFIKGVNFDLPHVLKHAPALPGVEHVGGDMFEVVPKGQVILLKRVLHDWKDEECLKILKNCYEALPESGKVVVIDMVLVDFPENDIVSKCVAQLDIAMLMVTHGGKERTEGEFGALAIAAGFAAYKFICRADLFGVIELYKKM
>Pg_S6095.5
MGSKTDMKLEEEEEEEACLFAMQLASASVLPMVLKSAIELDLLEKIAKAGPAAYVSHSDLASQLPAHHPGSAVMLDRILRLLTSYSVLICKLRELPDGGVERLYGLAPLCKFLTRNSDGVSMHGTSFAHEPR
>Pg_S2552.2
MASNDQEEFLKAVQFADSQAIHGVLSALFELNVFDIMMAKAGLDGYLSAVEIVSYLPTQNPQAPAILDRLLRLLATHSILKCTLVKTNGPSVAHLFLFGHSKAIADSWYCLKDTILEGGIPFNKAHEGMHIFEYLEKDRKLNQIFTEGMGKSTTSAMTKILEMYNGFEEVKEVVDVGGSHGETLGTIISKYPFIKGVNFDLPHVLKYAPALPGVEHVGGDMFEAVPKGQVILLKRVLHDWKDEECLKILKNCYEALPESGKVVVIDMVLVDFPENDIVSKCVAQLDIAMLMVTHGGKERTEGEFGALAIAAGFAAYKFICRADLFGVIELYKKNVNFSTFL
>Pg_S4267.1
MHIFEYLEKDRKLNQIFTEAMCMSTMNAMAKILEMYNGFEEVKEVIDVGGSLGETLATIISKYPFIKGVNFDLPHVLKHAPPALPGVEHIGGDMFEAVPRGQVILLKRVLHDWKDEECLKILKNCYEALPESGKVVVIDMVLRDFPENDLISKCVAQLDIGMLMLSHGGRERTEGEFGALARAAGFAAYKFMCHADLFGVFELYKKM
>Pg_S4267.2
MYLLFILAFHAKEKVIDRSTMASKDEDQEYFLKAVQLADSSVIHGVLRALVELNVFDIMMAKAGLDGYLSAVEIASYLPTQNPQAPAILDRMLRLLATHSILNCTLAKTSTTNHHDHDDDDDPPPPTRTYGLTPMSKYFVRDQGGPSVAQMLS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University