Enzyme
A copper-containing glycoprotein that plays a key role in the yellow coloration of flowers such as Antirrhinum majus (snapdragon). The enzyme is a homologue of plant polyphenol oxidase [1] and catalyses two separate chemical transformations, i.e. 3-hydroxylation and oxidative cyclization (2',-dehydrogenation). H2O2 activates reaction (1) but inhibits reaction (2). Originally considered to act on the phenol but now thought to act mainly on the 4'-O-beta-D-glucoside in vivo [4].
AS1
Enzyme
Aureusidin synthase
Enzyme name
EC:1.21.3.6
Entry
Oxidoreductases;Catalysing the reaction X-H + Y-H = X-Y;With oxygen as acceptor
Class
2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside:oxygen oxidoreductase
Sysname
(1) 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + O2 = aureusidin 6-O-beta-D-glucoside + H2O [RN:R08008];(2) 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + 1/2 O2 = aureusidin 6-O-beta-D-glucoside + H2O [RN:R08010];(3) 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + O2 = bracteatin 6-O-beta-D-glucoside + H2O [RN:R08009]
Reaction
aureusidin 6-O-beta-D-glucoside [CPD:C16409];H2O [CPD:C00001];bracteatin 6-O-beta-D-glucoside [CPD:C16410]
Product
Species information
Panax ginseng
Species name
Asiatic ginseng (Panax ginseng) is a species of eudicot in the family Araliaceae (ginseng family).
Species info
Gene sequence info
Panax_ginseng.AS1.fa
Download
>Pg_S1342.3
MSSFSLQTTTTIGATAYSYTTLSSSPLFDKPSQISITRKSYINFKVSCKALDDEQNPKTTSSKNNTFDRRNLLIGLGGLYGATSLGSNPSVFAAPLKAPELSKCGAADLPAGAKPTNCCPPFSGTVVDYRLPPPPTTLRVRPAAHLADKAYQAKFNKAIELMKALPDNDPRSFTQQANIHCAYCDGAYEQVGFPELDIQVHNSWLFFPFHRWYLYFFERILGKLIDDPTFAIPFWNWDSAGGMTMPAIYTDRNSPLFNRFRDAKHQSPALIDLDFNGTDENISKQQQVNQNLTIMYRQMVAGSKSARLFLGSPYRAGEESDPGGGNFEGTPHGPVHIWAGDRTQPNREDMGNFYSAGRDPLFYAHHSNCDRMWSIWKTLGGRRNDFTDKDWLDASFVFYDENAKLVSVKVGDCLDSKKLGYVYQNVDVAWLNTRPTPRLKRVLNKFKKFGEAKAADFSLAKDFFPRKLDKVVKVLVPRPRKNRSKKEKEEEEEVLVIEGIEVLRDAFVKFDVFINDEDEAASAPDKTEFAGSFVNVPHKHKHGKKIKTRLRLALTELLEDLGAEDDDNVLVTLVPKPGSSGFVSIKSIKIELDD
>Pg_S1395.16
MSSFSLQTTTTIGATAYSYTTLSSSPLFDKPSQISITRKSNRHFKVSCKALGDEQNPKTTSSKNNTFDRRNLLIGLGGLYGATSLGSNPSVFAAPLKAPELSKCGAADLPAGAKPTNCCPPFSGTVVDYRLPPPPTTLRVRPAAHLADKAYQAKFNKAIELMKALPDSDPRSFTQQANIHCAYCDGAYEQVGFPELDIQVHNSWLFFPFHRWYLYFFERILGKLIDDPTFATPFWNWDSAGGMTMPAIYTDRNSPLFNRFRDAKHQSPALIDLDFNGTDENISKQQQVNQNLTIMYRQMVAGSKSASLFLGSPYRAGEESDPGGGNFEGTPHGPVHIWAGDRTQPNREDMGNFYSAGRDPLFYAHHSNCDRMWSIWKTLGGRRNDFTDKDWLDASFVFYDENAKLVSVKVGDCLDSKKLGYVYQNVDVAWLNTRPTPRLKRVLNKFKKFGEAKAADFSLAKDVFPRKLDKVVKVLVPRPKKNRSKKEKEEKEEVLVIEGIEVERDAFVKFDVFINDEDEAASAADKTEFAGSFVNVPHKHKHGKKIKTRLRLALTELLEDLGAEDDDNVLVTLVPKPGSSGFVSIKSIKIELDD
>Pg_S1728.14
MVGFPDVKVDVHFSWLFFPFHRLYLYFYEKILGKLIDDPTFALPYWNWDSPPGMPIPAMFVNPYSPLYDKLRDAKHQPPLKIDLNYSKKNPSPTDEKRLIASNLSLMYKQMVSGSKTPRLFFGNAYRAGDVQAPGMGAVENQPHTQIHIWTGDPTQPNGEDMGRFYSAGRDPIFYAHHANVDRMWNIWKTLPGRNRKDIKDPDYLNAAFLFYDENKQLVRVKVKDSLDSRKLGYVYQDVDIPWLGYRPKPKQPQYPKLLDNVVKVVVPRPKKSRSKAEKEDEEEILVIDGIEFDGNVYVKFDVYINDKDEAESGPENAEFAGSFSNVPLKVKKKVKTCLKLGISELLEDLGADDDDEVLVAIVPKSGKGEVSIGGIKIEISS
>Pg_S3831.13
MASLQYFPIPSPTLWAAGSFYSKTSSFFINQKHSKKLSCRAKINDQEDNTIPRNEQNSTLNSLSKLDRRNILLALGGLYGGATAANLTPDALAAPVDVTKCGEATTLPASVAKIDCCPPSKETIIDFKFPPPPKILRVRPAAHLADEKYIARYSKAIALMKALPKDDPRSFTQQAGIHCAYCDSSYQMVGFPDVKVDVHFSWLFFPFHRLYLYFYEKILGKLIDDPTFALPYWNWDSPPGMPIPAMFANPYSPLYDKLRDAKHQPPLKIDLNYSKKNPSPTDEKRLIASNLSLMYKQMVSGSKNPRLFFGNAYRAGDAQAPGMGAVENQPHTPIHIWTGDPTQPNGEDMGRFYSAGRDPIFYAHHANVDRMWNIWKTLPGRNRKDIKDPDYLNAAFLFYDENKQLVRVKVKDSLDSRKLGYVYQDVDIPWVGYRPKPKQPRGKNKSGIANAAELPVEYPKLLDNVVKVVVPRPKKSRSKAEKEDEEEILVIDGIEFDGNVYVKFDVYIDDEDEAESGPESAEFAGSFSNVPLKVKKKVKTCLKLGISELLEDLGADDDDEVLVAIVPKSGKGEVSIGGIKIEISS
>Pg_S7486.1
MKALPANDPRSFIQQANVHCAYCDGAYEQVGFPELDIQVHNSWLFFPFHRWYLYFFERILGKLIDDPTFAMPFWNWDSAGGMRMPSMYTAQNSPLFNRLRDAKHQPPTMIDLDYSGTDPNITNQQQLSQNLTIMYRQMVAGSRTPRLFLGSPYRAGDDTDPGGGNFEGTPHGPVHIWTGDRTQPNIEDMGNFYSAARDPLFYAHHSNCDRMWSIWKTLGGRRQDFTDPDWLEASFVFYDENAQLVRVKVGDSLDNKKLGYTYQDVDLAWLNSRPTPRNSRVSRTIKKLGVANAADFGLAMDVFPRTLDKVVKFMVKRPKKNRSKKEKEEEEEVLVIDGIEVERDTFVKFDVFINDEDEAACTPDKTEFAGSFVNVPHKHRHGKKIKTRLRLGLTELLEDLGVEDDDNVMVTLVPKPGSTGVVSIKSVKIELDD
>Pg_S2069.15
MASFPPATTTTTVYSSSSVVSSSPFFARKSQISVTRKPNRRYKVSCKTIDGEKNPSTTSKNEKTNISLGNYNNKFDRRDLLIGLGGLYGATTLGSSPSSFAAPLKAPDLSKCGAADLPTGATPTNCCPPFSGTVVDYQLPPPPTALRVRPAAHLADKAYQDKFNKAIELMKALPANDPRSFIQQANVHCAYCDGAYEQVGFPELDIQVHNSWLFFPFHRWYLYFFERILGKLIDDPTFAMPFWNWDSAGGMRMPSMYTAQNSPLFNRLRDAKHQPPTMIDLDYSGTDPDITNQQQLSQNLTIMYRQMVAGSRTPRLFLGSPYRAGDDTDPGGGNFEGTPHGPVHIWTGDRTQPNIEDMGNFYSAARDPLFYAHHSNCDRMWSIWKTLGGRRQDFTDPDWLEASFVFYDENAQLVRVKVGDSLDNKKLGYTYQDVDLAWVNSRPTPRNSRVSRTIKKLGVANAADFGLAKDVFPRTLDKVVKFMVKRPKKNRSKKEKEEEEEVLVIDGIEVERDTFVKFDVFINDEDEAACTPDKTEFAGSFVNVPHKHRHGKKIKTRLRLGLTELLEDLGVEDDDNVMVTLVPKPGSTGVVSIKSVKIELDD
MSSFSLQTTTTIGATAYSYTTLSSSPLFDKPSQISITRKSYINFKVSCKALDDEQNPKTTSSKNNTFDRRNLLIGLGGLYGATSLGSNPSVFAAPLKAPELSKCGAADLPAGAKPTNCCPPFSGTVVDYRLPPPPTTLRVRPAAHLADKAYQAKFNKAIELMKALPDNDPRSFTQQANIHCAYCDGAYEQVGFPELDIQVHNSWLFFPFHRWYLYFFERILGKLIDDPTFAIPFWNWDSAGGMTMPAIYTDRNSPLFNRFRDAKHQSPALIDLDFNGTDENISKQQQVNQNLTIMYRQMVAGSKSARLFLGSPYRAGEESDPGGGNFEGTPHGPVHIWAGDRTQPNREDMGNFYSAGRDPLFYAHHSNCDRMWSIWKTLGGRRNDFTDKDWLDASFVFYDENAKLVSVKVGDCLDSKKLGYVYQNVDVAWLNTRPTPRLKRVLNKFKKFGEAKAADFSLAKDFFPRKLDKVVKVLVPRPRKNRSKKEKEEEEEVLVIEGIEVLRDAFVKFDVFINDEDEAASAPDKTEFAGSFVNVPHKHKHGKKIKTRLRLALTELLEDLGAEDDDNVLVTLVPKPGSSGFVSIKSIKIELDD
>Pg_S1395.16
MSSFSLQTTTTIGATAYSYTTLSSSPLFDKPSQISITRKSNRHFKVSCKALGDEQNPKTTSSKNNTFDRRNLLIGLGGLYGATSLGSNPSVFAAPLKAPELSKCGAADLPAGAKPTNCCPPFSGTVVDYRLPPPPTTLRVRPAAHLADKAYQAKFNKAIELMKALPDSDPRSFTQQANIHCAYCDGAYEQVGFPELDIQVHNSWLFFPFHRWYLYFFERILGKLIDDPTFATPFWNWDSAGGMTMPAIYTDRNSPLFNRFRDAKHQSPALIDLDFNGTDENISKQQQVNQNLTIMYRQMVAGSKSASLFLGSPYRAGEESDPGGGNFEGTPHGPVHIWAGDRTQPNREDMGNFYSAGRDPLFYAHHSNCDRMWSIWKTLGGRRNDFTDKDWLDASFVFYDENAKLVSVKVGDCLDSKKLGYVYQNVDVAWLNTRPTPRLKRVLNKFKKFGEAKAADFSLAKDVFPRKLDKVVKVLVPRPKKNRSKKEKEEKEEVLVIEGIEVERDAFVKFDVFINDEDEAASAADKTEFAGSFVNVPHKHKHGKKIKTRLRLALTELLEDLGAEDDDNVLVTLVPKPGSSGFVSIKSIKIELDD
>Pg_S1728.14
MVGFPDVKVDVHFSWLFFPFHRLYLYFYEKILGKLIDDPTFALPYWNWDSPPGMPIPAMFVNPYSPLYDKLRDAKHQPPLKIDLNYSKKNPSPTDEKRLIASNLSLMYKQMVSGSKTPRLFFGNAYRAGDVQAPGMGAVENQPHTQIHIWTGDPTQPNGEDMGRFYSAGRDPIFYAHHANVDRMWNIWKTLPGRNRKDIKDPDYLNAAFLFYDENKQLVRVKVKDSLDSRKLGYVYQDVDIPWLGYRPKPKQPQYPKLLDNVVKVVVPRPKKSRSKAEKEDEEEILVIDGIEFDGNVYVKFDVYINDKDEAESGPENAEFAGSFSNVPLKVKKKVKTCLKLGISELLEDLGADDDDEVLVAIVPKSGKGEVSIGGIKIEISS
>Pg_S3831.13
MASLQYFPIPSPTLWAAGSFYSKTSSFFINQKHSKKLSCRAKINDQEDNTIPRNEQNSTLNSLSKLDRRNILLALGGLYGGATAANLTPDALAAPVDVTKCGEATTLPASVAKIDCCPPSKETIIDFKFPPPPKILRVRPAAHLADEKYIARYSKAIALMKALPKDDPRSFTQQAGIHCAYCDSSYQMVGFPDVKVDVHFSWLFFPFHRLYLYFYEKILGKLIDDPTFALPYWNWDSPPGMPIPAMFANPYSPLYDKLRDAKHQPPLKIDLNYSKKNPSPTDEKRLIASNLSLMYKQMVSGSKNPRLFFGNAYRAGDAQAPGMGAVENQPHTPIHIWTGDPTQPNGEDMGRFYSAGRDPIFYAHHANVDRMWNIWKTLPGRNRKDIKDPDYLNAAFLFYDENKQLVRVKVKDSLDSRKLGYVYQDVDIPWVGYRPKPKQPRGKNKSGIANAAELPVEYPKLLDNVVKVVVPRPKKSRSKAEKEDEEEILVIDGIEFDGNVYVKFDVYIDDEDEAESGPESAEFAGSFSNVPLKVKKKVKTCLKLGISELLEDLGADDDDEVLVAIVPKSGKGEVSIGGIKIEISS
>Pg_S7486.1
MKALPANDPRSFIQQANVHCAYCDGAYEQVGFPELDIQVHNSWLFFPFHRWYLYFFERILGKLIDDPTFAMPFWNWDSAGGMRMPSMYTAQNSPLFNRLRDAKHQPPTMIDLDYSGTDPNITNQQQLSQNLTIMYRQMVAGSRTPRLFLGSPYRAGDDTDPGGGNFEGTPHGPVHIWTGDRTQPNIEDMGNFYSAARDPLFYAHHSNCDRMWSIWKTLGGRRQDFTDPDWLEASFVFYDENAQLVRVKVGDSLDNKKLGYTYQDVDLAWLNSRPTPRNSRVSRTIKKLGVANAADFGLAMDVFPRTLDKVVKFMVKRPKKNRSKKEKEEEEEVLVIDGIEVERDTFVKFDVFINDEDEAACTPDKTEFAGSFVNVPHKHRHGKKIKTRLRLGLTELLEDLGVEDDDNVMVTLVPKPGSTGVVSIKSVKIELDD
>Pg_S2069.15
MASFPPATTTTTVYSSSSVVSSSPFFARKSQISVTRKPNRRYKVSCKTIDGEKNPSTTSKNEKTNISLGNYNNKFDRRDLLIGLGGLYGATTLGSSPSSFAAPLKAPDLSKCGAADLPTGATPTNCCPPFSGTVVDYQLPPPPTALRVRPAAHLADKAYQDKFNKAIELMKALPANDPRSFIQQANVHCAYCDGAYEQVGFPELDIQVHNSWLFFPFHRWYLYFFERILGKLIDDPTFAMPFWNWDSAGGMRMPSMYTAQNSPLFNRLRDAKHQPPTMIDLDYSGTDPDITNQQQLSQNLTIMYRQMVAGSRTPRLFLGSPYRAGDDTDPGGGNFEGTPHGPVHIWTGDRTQPNIEDMGNFYSAARDPLFYAHHSNCDRMWSIWKTLGGRRQDFTDPDWLEASFVFYDENAQLVRVKVGDSLDNKKLGYTYQDVDLAWVNSRPTPRNSRVSRTIKKLGVANAADFGLAKDVFPRTLDKVVKFMVKRPKKNRSKKEKEEEEEVLVIDGIEVERDTFVKFDVFINDEDEAACTPDKTEFAGSFVNVPHKHRHGKKIKTRLRLGLTELLEDLGVEDDDNVMVTLVPKPGSTGVVSIKSVKIELDD
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University