Enzyme
A cytochrome P-450 (heme-thiolate) protein found in plants. Acts on a number of flavonoids, including the flavanone naringenin and the flavone apigenin. Does not act on 4-coumarate or 4-coumaroyl-CoA.
F3'H
Enzyme
Flavonoid 3'-hydroxylase
Enzyme name
EC:1.14.14.82
Entry
Oxidoreductases;Acting on paired donors, with incorporation or reduction of molecular oxygen;With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Class
flavonoid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Sysname
a flavonoid + [reduced NADPH---hemoprotein reductase] + O2 = a 3'-hydroxyflavonoid + [oxidized NADPH---hemoprotein reductase] + H2O [RN:R03615]
Reaction
3'-hydroxyflavonoid [CPD:C02790];[oxidized NADPH---hemoprotein reductase] [CPD:C03161];H2O [CPD:C00001]
Product
Species information
Panax ginseng
Species name
Asiatic ginseng (Panax ginseng) is a species of eudicot in the family Araliaceae (ginseng family).
Species info
Gene sequence info
Panax_ginseng.F3_H.fa
Download
>Pg_S6057.8
MPHHSIAAMVRTYGPLMHLRMGFVHVVVAASAEVAAQFLKTHDANFSSRPPNSGAKYMAYNYQDLVFAPYGSRWRMLRKICAVHLFSAKALDDFRHVREEEAAILTRALVDSGQERVKLGQLLNVCTTNALGRVMLGRRVFRDGSSAVDPKADEFKEMVVELMVLAGEFSIGDFIPALEWLDLQGVTLKMKKLHGRFDSFLSLILEEHKQRGRHGSSQQNHMDLLSMLLSLKKEEDDDQDGEGAGGQLLTDTEIKALLLNLFTAGTDTTSSTVEWAIAELVRNPKILAQAQKELDSVVGQERLVTDTDLTHLPYLQAIVKETFRLHPSTPLSLPRMASRSCEINGYYIPKDSTLLVNVWAIARDPNVWAQPLEFRPERFLPGGERPSADVKGNDFEVIPFGAGRRICAGMSFGLSMVQLVTATLVHAFNWELPEGELNMDESYGLTLQRAAPLVVHPQPRLAHHVYQISGYGS
>Pg_S2538.6
MHLRLGFVHVVVAASAEVAAQFLKTHDANFSSRPPNSGAKHIAYNYQDLVFAPYGSRWRKLRKICSVHLFSAKALDDFRHVRQEEVAILVRALAGVGKTPVNLGSLLNVCTTNSLGRVMLGRRVFSDGSRCVDPKADEFKEMVVELMALAGVFNIGDFIPALEWLDLQGVAKKMKKLHARFDLFLNQILEEHKDGAGHGSGGAGTKHVDLLSTLISLKDDVDGEGGKLNDTEIKALLLDLFTAGTDTSSSTVEWAMAEIFRNPKILDKAQKELDLVVGQDRLVMESDLAQLPYLQSIIKETFRLHPSTPLSLPRMAAESCEINGYFVPKDSTLLVNVWAIARDPNTWADPLEFRPQRFLTGGEKPTVDVKGTDFEVIPFGAGRRICAGMSLGLRMVQLLTATLVHAFSWELPEGHVAEKLNMEEAYGLTLQRAEPLMVHPRLRLAHQVYRA
>Pg_S4170.13
MPHHSIAAMARTYGPLMHLRMGFVHVVVAASAEVAAQFLKTHDANFSSQPPNSGAKYMAYNYQDLVFAPYGSRWRMLRKICAVHLFSAKALDDFRHVREEEAAILTRALVDSGQERVKLGQLLNVSTTNALGRVMLGRRVFRDGSSAVDPKADEFKEMVVELMVLAGEFSIGDFIPALEWLTCKV
>Pg_S4170.14
MKKLHGRFDSFLSLILEEHKQRGRHGSSSQQNHMDLLSMLLSLKKEEDDEVGEGAGGQLLADTEIKALLLVSILWANLAASYTFSSPPTTEARPSCVSIWIWEEGKLS
>Pg_S1097.4
MHLRLGFVHVVVAASAEVAAQFLKTHDANFSSRPPNSGAKHIAYNYQDLVFAPYGSRWRMLRKICSVHLFSAKALDDFRHVRQETCWHCRVDTGVGKTPVNLGSLLNRVFSDGSGCVDPKADEFKEMVVELMVLAGVFNIGDFIPALEWLDLQGVAKKMKNLHARFDLFLNQILEEHKDDVDGEGGKLNDTEIKALLLDLFTAGTDTSSSTVEWAMAEIFRNPKILAQAQKELDLVVGQHRLVMESDLTQLPYLQAIIKETFRLHPSTPLSLPTMAAESCEINGYFVPKDSTVLVNVWAIARDPNTWADPLEFRPQRFLTGGEKPTVDVKGTDFEVIPFGAGRRICAGMSLGLLMVQLLTATLVHSFSWELPEGHVAEKLNMEEAYGLTLQRAEPLMVHPRLRLAHQVYRA
>Pg_S1097.3
MLGRRVFSDGSGCVDPKADEFKEIVVELMVLAGVFNIGYFIPAFEWLDLQGVATKMKKLHARFDSFLNQILEEHKAGAGSGSGGAGTKHVDLLTTLISLKDDVDGEGGKLNDTGNKSTCLVPAPPLPLPAPPLCSSKICFKNKSNRACRFFIFLATPCKSSHSRAGIKSPMLNTPASTISSTTISLNSSALGSTQPLPSLNTL
MPHHSIAAMVRTYGPLMHLRMGFVHVVVAASAEVAAQFLKTHDANFSSRPPNSGAKYMAYNYQDLVFAPYGSRWRMLRKICAVHLFSAKALDDFRHVREEEAAILTRALVDSGQERVKLGQLLNVCTTNALGRVMLGRRVFRDGSSAVDPKADEFKEMVVELMVLAGEFSIGDFIPALEWLDLQGVTLKMKKLHGRFDSFLSLILEEHKQRGRHGSSQQNHMDLLSMLLSLKKEEDDDQDGEGAGGQLLTDTEIKALLLNLFTAGTDTTSSTVEWAIAELVRNPKILAQAQKELDSVVGQERLVTDTDLTHLPYLQAIVKETFRLHPSTPLSLPRMASRSCEINGYYIPKDSTLLVNVWAIARDPNVWAQPLEFRPERFLPGGERPSADVKGNDFEVIPFGAGRRICAGMSFGLSMVQLVTATLVHAFNWELPEGELNMDESYGLTLQRAAPLVVHPQPRLAHHVYQISGYGS
>Pg_S2538.6
MHLRLGFVHVVVAASAEVAAQFLKTHDANFSSRPPNSGAKHIAYNYQDLVFAPYGSRWRKLRKICSVHLFSAKALDDFRHVRQEEVAILVRALAGVGKTPVNLGSLLNVCTTNSLGRVMLGRRVFSDGSRCVDPKADEFKEMVVELMALAGVFNIGDFIPALEWLDLQGVAKKMKKLHARFDLFLNQILEEHKDGAGHGSGGAGTKHVDLLSTLISLKDDVDGEGGKLNDTEIKALLLDLFTAGTDTSSSTVEWAMAEIFRNPKILDKAQKELDLVVGQDRLVMESDLAQLPYLQSIIKETFRLHPSTPLSLPRMAAESCEINGYFVPKDSTLLVNVWAIARDPNTWADPLEFRPQRFLTGGEKPTVDVKGTDFEVIPFGAGRRICAGMSLGLRMVQLLTATLVHAFSWELPEGHVAEKLNMEEAYGLTLQRAEPLMVHPRLRLAHQVYRA
>Pg_S4170.13
MPHHSIAAMARTYGPLMHLRMGFVHVVVAASAEVAAQFLKTHDANFSSQPPNSGAKYMAYNYQDLVFAPYGSRWRMLRKICAVHLFSAKALDDFRHVREEEAAILTRALVDSGQERVKLGQLLNVSTTNALGRVMLGRRVFRDGSSAVDPKADEFKEMVVELMVLAGEFSIGDFIPALEWLTCKV
>Pg_S4170.14
MKKLHGRFDSFLSLILEEHKQRGRHGSSSQQNHMDLLSMLLSLKKEEDDEVGEGAGGQLLADTEIKALLLVSILWANLAASYTFSSPPTTEARPSCVSIWIWEEGKLS
>Pg_S1097.4
MHLRLGFVHVVVAASAEVAAQFLKTHDANFSSRPPNSGAKHIAYNYQDLVFAPYGSRWRMLRKICSVHLFSAKALDDFRHVRQETCWHCRVDTGVGKTPVNLGSLLNRVFSDGSGCVDPKADEFKEMVVELMVLAGVFNIGDFIPALEWLDLQGVAKKMKNLHARFDLFLNQILEEHKDDVDGEGGKLNDTEIKALLLDLFTAGTDTSSSTVEWAMAEIFRNPKILAQAQKELDLVVGQHRLVMESDLTQLPYLQAIIKETFRLHPSTPLSLPTMAAESCEINGYFVPKDSTVLVNVWAIARDPNTWADPLEFRPQRFLTGGEKPTVDVKGTDFEVIPFGAGRRICAGMSLGLLMVQLLTATLVHSFSWELPEGHVAEKLNMEEAYGLTLQRAEPLMVHPRLRLAHQVYRA
>Pg_S1097.3
MLGRRVFSDGSGCVDPKADEFKEIVVELMVLAGVFNIGYFIPAFEWLDLQGVATKMKKLHARFDSFLNQILEEHKAGAGSGSGGAGTKHVDLLTTLISLKDDVDGEGGKLNDTGNKSTCLVPAPPLPLPAPPLCSSKICFKNKSNRACRFFIFLATPCKSSHSRAGIKSPMLNTPASTISSTTISLNSSALGSTQPLPSLNTL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University