Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Oryza rufipogon
Species name
Common wild rice (Oryza rufipogon) is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Oryza_rufipogon.COMT.fa
Download
>R1009551.t1
MDKMTPAADGDDDETTCIRALELIFTFVVPMTLKATIKLGLLDALTGGGHALTADELAAAAQLPAEAASSVDRMLRLLASLDVVKCAPTDTGGEAAVRRYTPAPVCRWFAGERSLAPLAMFLLDDDYLSTWNQLPAAVAGGDGQVAFEKARGMPMFEYMGTNRRLNTLFNQAMVQQSTVVIGKLLERFQGFDGVSVLVDVGGGTGATLEMITSRYKNITGVNFDLPHVIAQAPSLPGVKHIAGNMFESVPNGDAIFLKSMLHLHNDEDCIKILKKCHQALTHNGKVIAVEILLPAIPEPVPTAQNPFRMDMIMLNNHWGGKERTEPEFAKLAVECGYTGVFQATYIFANYWALEFSK
>R1008826.t1
MFESIPNGDAIFLKSILHLQNDEDCIKILKNCHQSLSDNGKVIAVEIVLPAIPEPVPTAQYPFQMDMIMLNNFRGGKERTELEFTKLAMDSSFSGTLRTTYMFANYWALEFNK
>R1008823.t1
MDPYTSRAPASGGVAAGDDDEEAACLQAFELMCIFTVPMTLKAAIELGLLDALAAAGDGRALTADELAAARLPDAAPDKAEAASSVDRMLRLLASYNVVKCSTEAGPGGEPPRRRYSPAPVCRLFTAGGNSHRGSLAPSVLFGVDEDYLCTW
>R1008824.t1
MRMFEYMGTNRRLNTLFNQAMAQQSMIVINKLLDRFHGFDGVGVLVDVGGGTGATLEMITSRYKHITGVNFDLPQMILHMQNDEDCIKILKNCHQALPDNGKVIAVEIILPTIPELAQTARYPFQMDMIMLSNFRGGKERTELEFAKLATDSGFSGALRTTYILANYWVLEFSK
>R1008827.t1
MLRLLASCNVVKCSTEAGPAGEPLRRRYSPAPVCRWFTAGGNSHRGSLAPSVLFGIDEDYLSTWHQLAAVAFERAHGAPMFEYMGTNRRLNTLFNQAMAQQYMIVINKLLDRFHGFDGVGGGTGGTLEMIMSRHKHITGVNFDLPHVISQAPSLPAGYVLQ
>R1008825.t1
MVMTLRAAIQLGLIDALTAAADGRALTAGELVAQLPAVDDAGAASSVDRMLRLLASFNVVRCSTEAGPGGDPLRRYSPAPVCRWFTAGDNHQGSLAPRLMLDVDEDNLSTWAHGMPLFEYMGTNHRFNMLFNQAMSQQSMMVMNKLLDRFHGFDGISVLVDVGGGTGVTLKMIISRYKHITGVNFDLPHVISQAPSLPGVNHVAGNMFESVPKGDAIFLKSMLLRNDEECIKILKNCHYALSDNGKVIVVDIVLPATPKPVPEAQNPLRMDVMMLNNLRGGKIRTEQEYAKLAMDSGFSGSFRTTYIFANFMAIELCK
>R1027833.t1
MDNARESEDEHCLYAQELVFAYNRSMVLRAAIQLGLLDALAAGGDALTADELAGKIQATDGVAVDRILRFLASFDVVRCSTETSPGGGAALIRRYTPAPVCRWLTKNNGEGSLAPFSVFIIDEDHLLPWQHIAEAVASGGPAPSERTNGMPYHEYIGNNKRLSGLFDHAMAQHSAIRARKMLERFEGFDGIQRLVDVGGGDGSTLGMITSRYKHIRGINYDLPHVISQAPSLPGVEHIAGDMYESVPNGDAILLQWMLLMFSDEDCIKILKNCHQALPEGGKVIIVEGLLPETPNTTPAARDSFTMDMILFVLFKVGKHRTEEEFAKLAKESGFTGTFRSTYIFLNFYALEFNK
>R1023414.t1
MGGGGDGELSPAEARLAMMELANMISVPMALTAVIRLGVPAKLWAGGANAPLTAADLLPAGHPDPSVLERLLRLLASRGVFSEHTGSSSPSPRRFSLTAVGRTLVPGGGGSPSGSGASYADYVLQHHQDALVRAWPLLHEAVLDPSGPEPFARANAGVPAYAYYGKDREANEVMLRAMTGVSEPFMEALLEGYGDGGFEGVSTLVDVGGSSGACLEMMMRRVRTIRDGVNFDLPDVVAAAPPIPGVRHVGGDMFKSIPSGDAIFMKWVLTTWTNEECTAILSNCHKALPGGGKVIACEPVVPDTTDGSTRTRALLENDIFVMATYRTQGRERSEEEFRHLGLAAGFASFRAIYLDPFYAVLEYTK
>R1021709.t1
MYALELLGGSVVSMTLKAAIELGLVDELLAAAGAAVTAEELAARLRLPAAVAAAAAVDRMLRLLASYGVVRCATEAGPDGKARRSYAAAPVCKWLAAGSSSGEGSMAPLGLLNLDKVFMENWYYLKEAVSEGGTAFDKAYGTSLFQYLGQDGNEPSNTLFNQAMASHSVVITNKLLQFFRGFDAGAGVDVLVDVGGGVGATLRMITARHPHLRGVNYDLPHVIAQAPPVEGVEHIGGSMFDHVPSGSAILLKWILHLWGDEECVKILKNCYKALPAKGKVILVEYVLPASPEATLAAQEAFRLDVMMLNRLAGGKERTQQEFTDLAVDAGFSGDCKPTYIFTNVWALEFTK
>R1000446.t1
MGSTAADMAAAADEEACMYALQLASSSILPMTLKNAIELGLLETLQSAAVAGGGGKAALLTPAEVADKLPSKANPAAADMVDRMLRLLASYNVVRCEMEEGADGKLSRRYAAAPVCKWLTPNEDGVSMAALALMNQDKVLMESWYYLKDAVLDGGIPFNKAYGMTAFEYHGTDARFNRVFNEGMKNHSVIITKKLLDLYTGFDAASTVVDVGGGVGATVAAVVSRHPHIRGINYDLPHVISEAPPFPGVEHVGGDMFASVPRGGDAILMKWILHDWSDEHCARLLKNCYDALPEHGKVVVVECVLPESSDATAREQGVFHVDMIMLAHNPGGKERYEREFRELARAAGFTGFKATYIYANAWAIEFTK
>R1013388.t1
MRLLVHSGIFASDDAGTTYRLTPVSFFLVDGAAAAVPVVDGHLSQVPHVLASTSRHCLDTVAGLAGWFREDFPAPSPPSPFEHVHGVTPLESTARLGPEDAALFQEGLRVYDASGFAVVLRECRDVFDGVESLTDCGGGDGTAARAIAEAFPHVKCTVLDLARVVGDVPADGVVEYVAGDMFDFIPPSQSCDAQGN
>R1015724.t1
MDMPNEPRDQGEVRVAPKTTTAREVAMLPLSMLLVQLITVGVLLLSKLALNDGMSPFVIIVYRNLIASAVVAPLAVIFEREMWKKVNWSVVGWIFANAAFGDVLAMGLYFYGLRTTSATYSSIFMNLIPIATFLMAIVLRAEKLALGNWSGKLMLLGVLLCVGGTMVVNLVKGKACEGVPINILDDGADQPIGKLASLCGTVLVVLGLYAFLWGKGKELKLAATVAAQKEQQGGVILNTQKIQGYAELHNCGLAHLKSSALRDPAATTPFEMAHGMSPWSLTNNAMSHACVADSNLVMEIVLKEAHGIFHGLSSLIDVGGGHGAAAVAIAKVFPHITCSVLDLEQMAAAAHPQASIRRRVQSRHLARLCPPSPLPLPPHTQSVATVRYVNNSDNLLRVEAPNGLKHGSRWKMNQRVSNLVTFRVVAMLTPSSSIHLVSTPSSLMSRAGSGFAFIGLDRRHTISSLLHH
MDKMTPAADGDDDETTCIRALELIFTFVVPMTLKATIKLGLLDALTGGGHALTADELAAAAQLPAEAASSVDRMLRLLASLDVVKCAPTDTGGEAAVRRYTPAPVCRWFAGERSLAPLAMFLLDDDYLSTWNQLPAAVAGGDGQVAFEKARGMPMFEYMGTNRRLNTLFNQAMVQQSTVVIGKLLERFQGFDGVSVLVDVGGGTGATLEMITSRYKNITGVNFDLPHVIAQAPSLPGVKHIAGNMFESVPNGDAIFLKSMLHLHNDEDCIKILKKCHQALTHNGKVIAVEILLPAIPEPVPTAQNPFRMDMIMLNNHWGGKERTEPEFAKLAVECGYTGVFQATYIFANYWALEFSK
>R1008826.t1
MFESIPNGDAIFLKSILHLQNDEDCIKILKNCHQSLSDNGKVIAVEIVLPAIPEPVPTAQYPFQMDMIMLNNFRGGKERTELEFTKLAMDSSFSGTLRTTYMFANYWALEFNK
>R1008823.t1
MDPYTSRAPASGGVAAGDDDEEAACLQAFELMCIFTVPMTLKAAIELGLLDALAAAGDGRALTADELAAARLPDAAPDKAEAASSVDRMLRLLASYNVVKCSTEAGPGGEPPRRRYSPAPVCRLFTAGGNSHRGSLAPSVLFGVDEDYLCTW
>R1008824.t1
MRMFEYMGTNRRLNTLFNQAMAQQSMIVINKLLDRFHGFDGVGVLVDVGGGTGATLEMITSRYKHITGVNFDLPQMILHMQNDEDCIKILKNCHQALPDNGKVIAVEIILPTIPELAQTARYPFQMDMIMLSNFRGGKERTELEFAKLATDSGFSGALRTTYILANYWVLEFSK
>R1008827.t1
MLRLLASCNVVKCSTEAGPAGEPLRRRYSPAPVCRWFTAGGNSHRGSLAPSVLFGIDEDYLSTWHQLAAVAFERAHGAPMFEYMGTNRRLNTLFNQAMAQQYMIVINKLLDRFHGFDGVGGGTGGTLEMIMSRHKHITGVNFDLPHVISQAPSLPAGYVLQ
>R1008825.t1
MVMTLRAAIQLGLIDALTAAADGRALTAGELVAQLPAVDDAGAASSVDRMLRLLASFNVVRCSTEAGPGGDPLRRYSPAPVCRWFTAGDNHQGSLAPRLMLDVDEDNLSTWAHGMPLFEYMGTNHRFNMLFNQAMSQQSMMVMNKLLDRFHGFDGISVLVDVGGGTGVTLKMIISRYKHITGVNFDLPHVISQAPSLPGVNHVAGNMFESVPKGDAIFLKSMLLRNDEECIKILKNCHYALSDNGKVIVVDIVLPATPKPVPEAQNPLRMDVMMLNNLRGGKIRTEQEYAKLAMDSGFSGSFRTTYIFANFMAIELCK
>R1027833.t1
MDNARESEDEHCLYAQELVFAYNRSMVLRAAIQLGLLDALAAGGDALTADELAGKIQATDGVAVDRILRFLASFDVVRCSTETSPGGGAALIRRYTPAPVCRWLTKNNGEGSLAPFSVFIIDEDHLLPWQHIAEAVASGGPAPSERTNGMPYHEYIGNNKRLSGLFDHAMAQHSAIRARKMLERFEGFDGIQRLVDVGGGDGSTLGMITSRYKHIRGINYDLPHVISQAPSLPGVEHIAGDMYESVPNGDAILLQWMLLMFSDEDCIKILKNCHQALPEGGKVIIVEGLLPETPNTTPAARDSFTMDMILFVLFKVGKHRTEEEFAKLAKESGFTGTFRSTYIFLNFYALEFNK
>R1023414.t1
MGGGGDGELSPAEARLAMMELANMISVPMALTAVIRLGVPAKLWAGGANAPLTAADLLPAGHPDPSVLERLLRLLASRGVFSEHTGSSSPSPRRFSLTAVGRTLVPGGGGSPSGSGASYADYVLQHHQDALVRAWPLLHEAVLDPSGPEPFARANAGVPAYAYYGKDREANEVMLRAMTGVSEPFMEALLEGYGDGGFEGVSTLVDVGGSSGACLEMMMRRVRTIRDGVNFDLPDVVAAAPPIPGVRHVGGDMFKSIPSGDAIFMKWVLTTWTNEECTAILSNCHKALPGGGKVIACEPVVPDTTDGSTRTRALLENDIFVMATYRTQGRERSEEEFRHLGLAAGFASFRAIYLDPFYAVLEYTK
>R1021709.t1
MYALELLGGSVVSMTLKAAIELGLVDELLAAAGAAVTAEELAARLRLPAAVAAAAAVDRMLRLLASYGVVRCATEAGPDGKARRSYAAAPVCKWLAAGSSSGEGSMAPLGLLNLDKVFMENWYYLKEAVSEGGTAFDKAYGTSLFQYLGQDGNEPSNTLFNQAMASHSVVITNKLLQFFRGFDAGAGVDVLVDVGGGVGATLRMITARHPHLRGVNYDLPHVIAQAPPVEGVEHIGGSMFDHVPSGSAILLKWILHLWGDEECVKILKNCYKALPAKGKVILVEYVLPASPEATLAAQEAFRLDVMMLNRLAGGKERTQQEFTDLAVDAGFSGDCKPTYIFTNVWALEFTK
>R1000446.t1
MGSTAADMAAAADEEACMYALQLASSSILPMTLKNAIELGLLETLQSAAVAGGGGKAALLTPAEVADKLPSKANPAAADMVDRMLRLLASYNVVRCEMEEGADGKLSRRYAAAPVCKWLTPNEDGVSMAALALMNQDKVLMESWYYLKDAVLDGGIPFNKAYGMTAFEYHGTDARFNRVFNEGMKNHSVIITKKLLDLYTGFDAASTVVDVGGGVGATVAAVVSRHPHIRGINYDLPHVISEAPPFPGVEHVGGDMFASVPRGGDAILMKWILHDWSDEHCARLLKNCYDALPEHGKVVVVECVLPESSDATAREQGVFHVDMIMLAHNPGGKERYEREFRELARAAGFTGFKATYIYANAWAIEFTK
>R1013388.t1
MRLLVHSGIFASDDAGTTYRLTPVSFFLVDGAAAAVPVVDGHLSQVPHVLASTSRHCLDTVAGLAGWFREDFPAPSPPSPFEHVHGVTPLESTARLGPEDAALFQEGLRVYDASGFAVVLRECRDVFDGVESLTDCGGGDGTAARAIAEAFPHVKCTVLDLARVVGDVPADGVVEYVAGDMFDFIPPSQSCDAQGN
>R1015724.t1
MDMPNEPRDQGEVRVAPKTTTAREVAMLPLSMLLVQLITVGVLLLSKLALNDGMSPFVIIVYRNLIASAVVAPLAVIFEREMWKKVNWSVVGWIFANAAFGDVLAMGLYFYGLRTTSATYSSIFMNLIPIATFLMAIVLRAEKLALGNWSGKLMLLGVLLCVGGTMVVNLVKGKACEGVPINILDDGADQPIGKLASLCGTVLVVLGLYAFLWGKGKELKLAATVAAQKEQQGGVILNTQKIQGYAELHNCGLAHLKSSALRDPAATTPFEMAHGMSPWSLTNNAMSHACVADSNLVMEIVLKEAHGIFHGLSSLIDVGGGHGAAAVAIAKVFPHITCSVLDLEQMAAAAHPQASIRRRVQSRHLARLCPPSPLPLPPHTQSVATVRYVNNSDNLLRVEAPNGLKHGSRWKMNQRVSNLVTFRVVAMLTPSSSIHLVSTPSSLMSRAGSGFAFIGLDRRHTISSLLHH
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University