Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Oropetium thomaeum
Species name
Oropetium thomaeum is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Oropetium_thomaeum.HIDH.fa
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>Oropetium_20150105_05660A.v1.0
MATIWEFACPGAVGGADDPRMNPMAQGAPGLENLRCERLLVCIGAEDWATPRNRAYYAALSSSAWRGKAAWIESEGEGNVFFLQKPECEKAKELMDRVVSFIAGS
>Oropetium_20150105_05659A.v1.0
MDPGYLQSAARTWNFICAGRYPINHPYADPLMLPASSWQRLGCSRVLVTVSEMDRLSPWQRAYYATLKGSGWPGQAELYETPGEGHVYFLTKLATPQALAEMTKLVAFINRD
>Oropetium_20150105_05657A.v1.0
MFDPTWDFVCGGRFGPEHPHINPMASPEEWRQLGSRRVLVTTAEKCWFVERARAYAEGIKKCGWEGELQFYETKGEEHVFFLPKHGSDNAVKELAVVADFVRRS
>Oropetium_20150105_05662A.v1.0
MAMEEPGADEVVFDAPEYFRVYKSGRIDRFHRPGETERALEIGTKVWSFSCPDAADGADDPQFNPVCAPRLLEQLGCERMLVCAAEQDWLAPRIRAYYGAVAASAWPGSAAWLETQGEGHVFFLMKPECDKAKALLDRIVAFIAAA
>Oropetium_20150105_05663A.v1.0
PEGGSATFAGLWLYACPSAVGGADDPRFNPLAPGAPALEKLGCARMLVCAGKEDGLYARDRAYHDALAASAWPGTVEWHESDGEGHDFFLGKPECENAKRLMDCIVAFIAGEPELGSL
>Oropetium_20150105_05658A.v1.0
MAASRRGLPSGALLEGAIILHPMFGGNEPIEGEDRETRATAERLWPLICPQGTRGLDDPWFNPLAEGAPSLQNLACRKLLVCSAERDYARPRTAAYNQAVRESGWRGSVEWFESKGEEHVFFLHKPECDESLALMDRLLAFLAND
>Oropetium_20150105_05664A.v1.0
MLVCAATEDKLFARDRVYYDAVAASAWPGTVEWLESDGEEHVFFLQKPECENAKRLMDRVVALIAGA
>Oropetium_20150105_05655A.v1.0
MWHTVCPATTGVNDPWINPLAAGAPAMDALACGRVLMCLAEKDVISDRGRAYVEGLRASGWAGEVEVLEVDGKGHCFHLVDFACVDAVTQDDAIARLVNR
>Oropetium_20150105_10617A.v1.0
LSRRASASFNGVSTAAHAQAHAHYGGRTTAKGAGADTFGAAMVEPWLAAHADPSRCVLLGVSCGANIADYVARKAVEAGKLLDPVQIVAQVLMYPFFMGSTPTQSELKLANSYFYDKPMCLLAWKLLLPDNEFSMDHPAANPLVPGRGPPLSLMPPTLTVVAELDWMKDRAIAYSEELRKVNVDAPVLEYKDAVHEFATLDVMLKTPQAQACAEDIAIWVKNINLSEPT
>Oropetium_20150105_07613A.v1.0
MLVCAAKEDKLFPRNRAYYDAVAACAWSGTVEWLQSEGEDHGFFLKRPECENAKHLMNRVVTFIVGA*SRIGSQCLHSAIFEP
>Oropetium_20150105_17143A.v1.0
MAGHRVLVTVAGRDGFRDRGLAYADGLRRCGWRGEVEVYVTEGEPHVHFVGNPRSERAERETDKFVIKERKAKKGTTGKAAKALADAFWRFLYPGSPGLDDPLSNPFSDGSAARIAAERVLVCVAEKDELRDRGVWYYENLKASGYSGEVELLESMGEGHVFYCINPRCDKAREMQDRILSFLRK
MATIWEFACPGAVGGADDPRMNPMAQGAPGLENLRCERLLVCIGAEDWATPRNRAYYAALSSSAWRGKAAWIESEGEGNVFFLQKPECEKAKELMDRVVSFIAGS
>Oropetium_20150105_05659A.v1.0
MDPGYLQSAARTWNFICAGRYPINHPYADPLMLPASSWQRLGCSRVLVTVSEMDRLSPWQRAYYATLKGSGWPGQAELYETPGEGHVYFLTKLATPQALAEMTKLVAFINRD
>Oropetium_20150105_05657A.v1.0
MFDPTWDFVCGGRFGPEHPHINPMASPEEWRQLGSRRVLVTTAEKCWFVERARAYAEGIKKCGWEGELQFYETKGEEHVFFLPKHGSDNAVKELAVVADFVRRS
>Oropetium_20150105_05662A.v1.0
MAMEEPGADEVVFDAPEYFRVYKSGRIDRFHRPGETERALEIGTKVWSFSCPDAADGADDPQFNPVCAPRLLEQLGCERMLVCAAEQDWLAPRIRAYYGAVAASAWPGSAAWLETQGEGHVFFLMKPECDKAKALLDRIVAFIAAA
>Oropetium_20150105_05663A.v1.0
PEGGSATFAGLWLYACPSAVGGADDPRFNPLAPGAPALEKLGCARMLVCAGKEDGLYARDRAYHDALAASAWPGTVEWHESDGEGHDFFLGKPECENAKRLMDCIVAFIAGEPELGSL
>Oropetium_20150105_05658A.v1.0
MAASRRGLPSGALLEGAIILHPMFGGNEPIEGEDRETRATAERLWPLICPQGTRGLDDPWFNPLAEGAPSLQNLACRKLLVCSAERDYARPRTAAYNQAVRESGWRGSVEWFESKGEEHVFFLHKPECDESLALMDRLLAFLAND
>Oropetium_20150105_05664A.v1.0
MLVCAATEDKLFARDRVYYDAVAASAWPGTVEWLESDGEEHVFFLQKPECENAKRLMDRVVALIAGA
>Oropetium_20150105_05655A.v1.0
MWHTVCPATTGVNDPWINPLAAGAPAMDALACGRVLMCLAEKDVISDRGRAYVEGLRASGWAGEVEVLEVDGKGHCFHLVDFACVDAVTQDDAIARLVNR
>Oropetium_20150105_10617A.v1.0
LSRRASASFNGVSTAAHAQAHAHYGGRTTAKGAGADTFGAAMVEPWLAAHADPSRCVLLGVSCGANIADYVARKAVEAGKLLDPVQIVAQVLMYPFFMGSTPTQSELKLANSYFYDKPMCLLAWKLLLPDNEFSMDHPAANPLVPGRGPPLSLMPPTLTVVAELDWMKDRAIAYSEELRKVNVDAPVLEYKDAVHEFATLDVMLKTPQAQACAEDIAIWVKNINLSEPT
>Oropetium_20150105_07613A.v1.0
MLVCAAKEDKLFPRNRAYYDAVAACAWSGTVEWLQSEGEDHGFFLKRPECENAKHLMNRVVTFIVGA*SRIGSQCLHSAIFEP
>Oropetium_20150105_17143A.v1.0
MAGHRVLVTVAGRDGFRDRGLAYADGLRRCGWRGEVEVYVTEGEPHVHFVGNPRSERAERETDKFVIKERKAKKGTTGKAAKALADAFWRFLYPGSPGLDDPLSNPFSDGSAARIAAERVLVCVAEKDELRDRGVWYYENLKASGYSGEVELLESMGEGHVFYCINPRCDKAREMQDRILSFLRK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University