Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Oropetium thomaeum
Species name
Oropetium thomaeum is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Oropetium_thomaeum.CHS.fa
Download
>Oropetium_20150105_24353A.v1.0
PDRPYDLVGVALFGDGAGAAVIGADPSPLERPLFELHTALQRFLPDTEKT
>Oropetium_20150105_13406A.v1.0
MEDIPSRVHQIRSAQRAHGPAAVLAIGTANPANCILQDDYPDFYFQRAPHHRPQTQAQDNK
>Oropetium_20150105_13405A.v1.0
MLFLNAHPELLDGYTSAPSLDTRLAIWGKPATDITHLVVSTSSGAQLPGVDFSLVPLLGLRPDVRRTMLYHNGCFAGGAAMRVAKDLAENNRGARVLVVCADMTVMLFRGPDPKEGEEGCFIQTLIDQMLFGDGAGAVIVGADPVAPIERPLFEMVLAAQTAIPNSSHALHMRITSAGIRGATAMPETLGTFIGDNAERLILDACGSLGIDVAEWNDLFWVVHPGAPAILDRIEVALKLKPGKLAASRHILSEYGNMFGATVTFVLDEQRRRMEEEGKEETLEWGIMMAVGPGLTIEVMIVPAATVRELWLARRADGPAAVLAIGTANPSTCALLAAHPELLDNGSPSLDARLDVVKSAVPELAASAARKAVAAWGRPAGDVTHLVVATNSGAHIPGVDFRLVKLLGLRADVRRTMLYLNGCFAGAAALRLAKDLAENSRGARVLVVCAELASVLLFTAPEEGCFQTLVNQGLFGDGAGAVIVGASADDDLASVERPLFEIVAATQTIVPDSEDAIAMHLTNRGFGGNISTRQVPILVGDNVERCLADTLGPLGVTTGSDQWNDMFWAVHPGSSAILDRVEAVLKLQPEKLVASRHVLSEYGNMFGATVIFILEELRQRMEKGEETGAPEWGAMMAFGPGLTVETIALHRCAAAHGDVAKADVA
>Oropetium_20150105_21582A.v1.0
MALFGDGAGAAIVGAGPILSIERPVFHMVSAAQAMPATEHAVRLSVSESGLDIKMSVEVPKLVGGGVERCLLGMLTPFGLAGRDWNNGLFWAAHPSGRAFAGFAVPMASTAAVPSTRRARRHASSSTVAGRPVANMVVDRSGKKSGIKKRYKKIEEKIHGHPDMLDPGLPSLGSRLGLAADAVPELPASARAIAEWGRPAADITHLVVSTSSGARYADLPLAALLGLHPTVRRTMLYLRVAKDLAENNRGARVLVVCAEATLLFYHAPDEARLDKLVAATLFGDGAGAAIVGAGPSPVHERPIFHMASASQVTLPGTEHAVELQLGENGLDYGMSSELPALARGNVERCLTEALAPLGLAAGGWNGFFWAAHPGGRAILDGYEDALGLDPGKLAASRHVLSEYGNMLGATNRHFSFTEETLSGHPEFLDRAQPSLSTRAGIAASAVPDLGLSAARRAIAEWGRPAADVTHLVVSTNSGCRAPGADLRLASLLGLRPTVQRTLLYLHGCFGGLSALRVAKDLAENSPGARVLVVCSEVMSLLAFRAPEDGMMDALIVGTLFGDGAGAVIVGAGPILEPAERPIFHMVSASQTTVPGIEHALTMQLGESGLDYGMSAEVPRLVRGCVEGCLAADTLVGPLGRHAGGPGGDGWNSFFWAVHPGGRAVLDSCEAALSLEPGKLAASRRVLSKYGNMGGATILFVLDEMRRRRHEREVDDVEEEQNMCDCEWGVMLGLDPGSPSRRWSCALPPARMKSSYISTVHKYTLYRIMNGSWIIYY
>Oropetium_20150105_21585A.v1.0
MAGGGAAAKVTVEEVRQAQRASGPATVLAIGTATPANCVYQADYPDYYFRITKSEHLTDLKEKFKRMCE
>Oropetium_20150105_21453A.v1.0
HVDTLVVQALFGDGAGAAIVGSSSSSSSDNGEIGFGSEERPLFEMALKLNPSKLAASRHVLSEYGNLSGASTLFVLDEVRRRRGRAARDRKNEAEEECEELGAMVALGPG
>Oropetium_20150105_27962A.v1.0
SSARTRSSSTGTCRPSPRAIDIAAAAVPKLAESAARKAIVEWGRPASEITHLVFSTYSSYRAPSADLALASLLGLPRHGQPHRAEPPRLLRRRPGAAAGQGHRREQPRRARAGGLLRDRRSSASPGPDGGNLVGHALFGDGAGAAIVGAAPFHALGMQVAAGGIDFHLAIQTVLKLDPGKLAASRRVLREYGNMSGATILFVLDELRRQRTKEEEGGHQQQLPEWGALLAFGPGITVETIVCAPPRNLKKH
PDRPYDLVGVALFGDGAGAAVIGADPSPLERPLFELHTALQRFLPDTEKT
>Oropetium_20150105_13406A.v1.0
MEDIPSRVHQIRSAQRAHGPAAVLAIGTANPANCILQDDYPDFYFQRAPHHRPQTQAQDNK
>Oropetium_20150105_13405A.v1.0
MLFLNAHPELLDGYTSAPSLDTRLAIWGKPATDITHLVVSTSSGAQLPGVDFSLVPLLGLRPDVRRTMLYHNGCFAGGAAMRVAKDLAENNRGARVLVVCADMTVMLFRGPDPKEGEEGCFIQTLIDQMLFGDGAGAVIVGADPVAPIERPLFEMVLAAQTAIPNSSHALHMRITSAGIRGATAMPETLGTFIGDNAERLILDACGSLGIDVAEWNDLFWVVHPGAPAILDRIEVALKLKPGKLAASRHILSEYGNMFGATVTFVLDEQRRRMEEEGKEETLEWGIMMAVGPGLTIEVMIVPAATVRELWLARRADGPAAVLAIGTANPSTCALLAAHPELLDNGSPSLDARLDVVKSAVPELAASAARKAVAAWGRPAGDVTHLVVATNSGAHIPGVDFRLVKLLGLRADVRRTMLYLNGCFAGAAALRLAKDLAENSRGARVLVVCAELASVLLFTAPEEGCFQTLVNQGLFGDGAGAVIVGASADDDLASVERPLFEIVAATQTIVPDSEDAIAMHLTNRGFGGNISTRQVPILVGDNVERCLADTLGPLGVTTGSDQWNDMFWAVHPGSSAILDRVEAVLKLQPEKLVASRHVLSEYGNMFGATVIFILEELRQRMEKGEETGAPEWGAMMAFGPGLTVETIALHRCAAAHGDVAKADVA
>Oropetium_20150105_21582A.v1.0
MALFGDGAGAAIVGAGPILSIERPVFHMVSAAQAMPATEHAVRLSVSESGLDIKMSVEVPKLVGGGVERCLLGMLTPFGLAGRDWNNGLFWAAHPSGRAFAGFAVPMASTAAVPSTRRARRHASSSTVAGRPVANMVVDRSGKKSGIKKRYKKIEEKIHGHPDMLDPGLPSLGSRLGLAADAVPELPASARAIAEWGRPAADITHLVVSTSSGARYADLPLAALLGLHPTVRRTMLYLRVAKDLAENNRGARVLVVCAEATLLFYHAPDEARLDKLVAATLFGDGAGAAIVGAGPSPVHERPIFHMASASQVTLPGTEHAVELQLGENGLDYGMSSELPALARGNVERCLTEALAPLGLAAGGWNGFFWAAHPGGRAILDGYEDALGLDPGKLAASRHVLSEYGNMLGATNRHFSFTEETLSGHPEFLDRAQPSLSTRAGIAASAVPDLGLSAARRAIAEWGRPAADVTHLVVSTNSGCRAPGADLRLASLLGLRPTVQRTLLYLHGCFGGLSALRVAKDLAENSPGARVLVVCSEVMSLLAFRAPEDGMMDALIVGTLFGDGAGAVIVGAGPILEPAERPIFHMVSASQTTVPGIEHALTMQLGESGLDYGMSAEVPRLVRGCVEGCLAADTLVGPLGRHAGGPGGDGWNSFFWAVHPGGRAVLDSCEAALSLEPGKLAASRRVLSKYGNMGGATILFVLDEMRRRRHEREVDDVEEEQNMCDCEWGVMLGLDPGSPSRRWSCALPPARMKSSYISTVHKYTLYRIMNGSWIIYY
>Oropetium_20150105_21585A.v1.0
MAGGGAAAKVTVEEVRQAQRASGPATVLAIGTATPANCVYQADYPDYYFRITKSEHLTDLKEKFKRMCE
>Oropetium_20150105_21453A.v1.0
HVDTLVVQALFGDGAGAAIVGSSSSSSSDNGEIGFGSEERPLFEMALKLNPSKLAASRHVLSEYGNLSGASTLFVLDEVRRRRGRAARDRKNEAEEECEELGAMVALGPG
>Oropetium_20150105_27962A.v1.0
SSARTRSSSTGTCRPSPRAIDIAAAAVPKLAESAARKAIVEWGRPASEITHLVFSTYSSYRAPSADLALASLLGLPRHGQPHRAEPPRLLRRRPGAAAGQGHRREQPRRARAGGLLRDRRSSASPGPDGGNLVGHALFGDGAGAAIVGAAPFHALGMQVAAGGIDFHLAIQTVLKLDPGKLAASRRVLREYGNMSGATILFVLDELRRQRTKEEEGGHQQQLPEWGALLAFGPGITVETIVCAPPRNLKKH
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University