Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Olea europaea
Species name
Common olive (Olea europaea) is a species of eudicot in the family Oleaceae (olive famly).
Species info
Gene sequence info
Olea_europaea.ROMT.fa
Download
>rna-XM_023043054.1
MAFPIGEKSVELLQAEAKFWNYEFNFLYMASLKCATKLGIPDIIHKHGKPMTLQQLGDALPINKTKIHGVHRLMRVLVHSRFFIEEKVSEDDTNMGYWLTPASRLLIKDQALSMIPFVEASFDPTYLKPWYHMSEWFQNDDLSAFETAHGSSLWDYACHDPKLNQAFNEDMSKDTEFLSSIIIRECKNVFDKMNSMVDVGGNTGFMAKAIVDAFPHLHCSVFDLPHVIEGLEGSYKNLTYIKGNMFESIPQADAIMLKWILHDWSDEECVKILKKCKEAIPRKENGGKVIIIDMIVGNNKEDHQHTETQLFNDLAMMLYLNGKERTEKEWEKLFFDAGYSGYKIAYELGLRSLIEVYP
>rna-XM_023043594.1
MAIPTGEQSVELLQAQAKFWNHKINVIYIASFKCVTELGIPDIIHKHGKPMTLQQLADALSISKAKVHGSSSRKKFPRMTQIWGIGLHQLLVSSSKTRQPIEHVIEGLEGSKNLTYIKGNMFESIPQADAIMLKWILHDWSDEKCVKILKKCKEAIPSKENGGKVIIIDMIIRNNKEDHQHTETQLFSDLLMMVLFNGKERSEKEWEKLFFDAGYRGYKIAYELGLRSLVKLYTTTKVGFYCMKRAFMACR
>rna-XM_022994210.1
MAFLIGEQSTELLQAQAHVWNHIFNYVNSMSLKCATQLGIPDIIHRHGKPMTLEELVDVLHLNSAKAQAVYRLMRILTHLGFFVEEKVSEDDSNMGYWLTQASRLLLKDDALSSLPFLQVALDPLLIKPWHHMSEWFENNEDSSAFETAYGKTFWGYGSQEPKMNLLFKKAMASDTQLVSNVVTRDCKQVFQKLKSIVDVGGGTGSLAKAIVDSFPDLQCVVFDLPHVIAGLEGTKNLTYVGGNMFETIPRADALLLKVWSLFIRPTNKIETFTLFCN
>rna-XM_022994063.1
MEEKLKNCIEYITEYMNLATHEWKDVKENGQSSSDAGFTHYKIAHKLGYKSLIEVYPEWFENNEDSSAFETAYGKTFWDYGSQEPKMNLLFNKAMASDTQLVSNVVTRDCKQVFEKLKSIVDVGGGTGSLAKAIVDSFPDLQCVVFDLPHVIAGLEGTKNLTYVGGNMFETIPRADALLLKCILHDWSDEDCVKILKKCREAIPCKENGGKVIIIDIIVGNKKEDHKGIETQLFYDMSMMVWANGRERTEKEWAKLFFDAGFTRYNIVYGLGLRSIIEVYP
>rna-XM_022994272.1
MALPIGEQSTELLQAQAHVWNHIFNYVNSISLKCATQLGIPDIIHRHGKPMTVQELVDALHINSAKAQAVHRLMRILTHLGFFVEEKVSEDDSNMGYWLTQASRLLLKDDALSVLPSLQIALDPLLIKPWHHMSEWFENNEDSSAFETAYGRTFWDYGSQEPKMNQLFNKAIASDTQLVSNVVARDCKQVLEKLKSIVDVGGGTGSMAKAIVDSFPDLHCIVFDLPHVIAGLEGTKNLTYVGGNMFETIPRADALLLKCILHDWSDEDCVKILKKCREAIPCKENGGKVIIIDIIIGNKKEDHKGIGTELFYDMSMMIFANGRERIEKEWAKLFFDAGFTGYNIVYGLGLRSIIEVYP
>rna-XM_023001811.1
MAFLIGEQSAELLQAQAKFWNHEYNFIYIASLKCVTQLGIPDIIYKHGKPITLQQLADVLPINKAKVHGVYRLIRVLVHSGFFTKEKVSDDVANMGYWLTPASRLLIKDQSLSMIPVLEASFYPTYLKPWHHMSEWFQNDDLSAFETAHGSTLWDYASHDPKLNEFFNEHMVNDTELLSRIVIRDCQNVFDNMKSMVDVGGNTGFMAKAIADAFPHLHCAVFDLPHVVAGLKGSKNLTYIEGNMFESIPQADAVMLKWILHDWSDEESLKILKKCKEAIPSKENGGKVIIVDMIVRNNKEDHQQTETQLFYDLLMMVLINGKERTEKEWEELFFDAGYSGYKIAYELGLWSLIEVYP
>rna-XM_023007988.1
MAFLIGEQSVELLQAQAKFWNHEYNFIYIASLKCVTQLGIPDIIYKHGKPITLQQLANVLPINKAKVHGVYRLMRVLVHSGFFIKEKVSDDDADMGYWLTPASRLLIKDQALSMIPFLEASFYPTYLKPWHHMSEWFQNDDLSAFETAHGSTLWDYASHDPKLNELFNEHMVNDTESLSRIVIRDCQNVFHNMKSMVDVGGNTGFMAKAIADAFPHLHCTLFDLPHVVAGLTGSKNLTYIEGNMFESIPQADAVMLKWILHDWSDEESVKILKKCKVAIPSKENEGKVIIIDMIVRNNKEDHQETETQLFYDLLMMVLNNGKERTEKEWEEVFFDAGHSGYKIAYELGLWSLIEVYP
>rna-XM_023013933.1
FTAELLKAQAKFWNHIFTFPYMASLKCVTELGIPDIIHKHGKPMTLQQLGDALPINKAKVQGVYRLMRFLVHSGFFIEKKVSEDDTNMGYWLTPASQLLIKDQALSMIPFLQSCLNPIYVKPWNHITEWLQNDDHSAFKIAHGCTLWDYACRDPKFSQSLNEDLCDDTDMLSRIIIRDCKNVFDKINSMVDVGGNTGFMAKAIADAFPHLRCAVFDLPHIVEGLEGSYKNLTYIKGNMFESIPQADAIMLKWILHDWSDEECVQILKKCKEAIPRKENGGKVIIIDMIVGNNKEDHQHTETQIFNDLAMMVFLNGKERTEKEWEKLFLDAGYSGYKIAYDLGLRSLIELYP
>rna-XM_023018336.1
MTIIFGDSSKSAKRWLGYKVIDKIPNNYEHRFPVEPFAAKPTIGPRGWGVGVRALERVYIASQCPSTSTKFKQNGEQSTELLHAQAHIWNQIFNFINSMSLKCAIQLGIPDIIHKHGKPMTLPELVDALPIDKAKSQCVSRLMRILTHSRFFIDAKIFENEENMGYWLTSASRLLLKDEPLSVTPFLLAMLDPILTEPWHHLSEWFESDQNPTAFDTKHGRMFWEYAGREPRLNSFFNEAMASDARLVTSVLIRDCKHVFEGLNSIVDVGGGTGTLSKNIADAFPNLKCTVLDLPHVVAGLEGTKNLSYLGGDMFESIPSADAILLKWILHDWSDEECVKILKTCKEAIQSTDKEGKIIIIDMIIDNQKEDNKAIETQLHFDMLMMALLTGRERNEKEFATIFYDAGFTRYKIIPILGLRSVIEVYP
>rna-XM_023018337.1
MDIKGLLLLVLIQVNFFSRVIDPCATHNYEHRFPVEPFAAKPTIGPRGWGVGVRALERVYIASQCPSTSTKFKQNGEQSTELLHAQAHIWNQIFNFINSMSLKCAIQLGIPDIIHKHGKPMTLPELVDALPIDKAKSQCVSCLMRILTHSRFFIDAKISENEENMGYWLTSASRLLLKDEPLSVTPFLLAMLDPILTEPWHHLSEWFESDQNPTAFDTKHGRMFWEYAGHEPRLNSFFNEAMASDARLVTSVLIRDCKHVFEGLNSIVDVGGGTGTLSKNIADAFPNLKCTVLDLPHVVAGLEGTKNLSYLGGDMFESIPSADAILLKWILHDWSDEECVKILKTCKEAIQSTHKEGKIIIIDMIIDNQKEDNEAIETQLQFDMLMMAIVTGRERNEKEWATIFYDAGFTNYKIIPILGLRSVIEVYP
>rna-XM_023018322.1
MPLPNGEVQFSELLRAQSHVWNHIFNFINSISLKSAIQLGIPDIILKHGKPMTLPELVDILRINKAKAHGVYRLMRILIHSGFFIEEKISQNEEKKGYWLTSASRLLLKEEPFSLAPLLLVVLDPFLTEPWHYVAEWLKDDHPTPFSTLHGRSFWAYAGQDPKLNHLFNNAMANDSRLITSVVIRDCKHVFEGLNSIVDVAGGTGTMAKAIAETFPNLKCTVLDLPHVVAGLKGTKNLCYVGGDMFETIPNADAILLKWILHDWSDEECIKILKKCKEAIPSKEEGGKLIIIDMVVVDNQKEEEEIIESQLFFDMMMMVAVGGIEREEREWMKLLKASGFSHYKIINKLGSRSLIEVYPS
MAFPIGEKSVELLQAEAKFWNYEFNFLYMASLKCATKLGIPDIIHKHGKPMTLQQLGDALPINKTKIHGVHRLMRVLVHSRFFIEEKVSEDDTNMGYWLTPASRLLIKDQALSMIPFVEASFDPTYLKPWYHMSEWFQNDDLSAFETAHGSSLWDYACHDPKLNQAFNEDMSKDTEFLSSIIIRECKNVFDKMNSMVDVGGNTGFMAKAIVDAFPHLHCSVFDLPHVIEGLEGSYKNLTYIKGNMFESIPQADAIMLKWILHDWSDEECVKILKKCKEAIPRKENGGKVIIIDMIVGNNKEDHQHTETQLFNDLAMMLYLNGKERTEKEWEKLFFDAGYSGYKIAYELGLRSLIEVYP
>rna-XM_023043594.1
MAIPTGEQSVELLQAQAKFWNHKINVIYIASFKCVTELGIPDIIHKHGKPMTLQQLADALSISKAKVHGSSSRKKFPRMTQIWGIGLHQLLVSSSKTRQPIEHVIEGLEGSKNLTYIKGNMFESIPQADAIMLKWILHDWSDEKCVKILKKCKEAIPSKENGGKVIIIDMIIRNNKEDHQHTETQLFSDLLMMVLFNGKERSEKEWEKLFFDAGYRGYKIAYELGLRSLVKLYTTTKVGFYCMKRAFMACR
>rna-XM_022994210.1
MAFLIGEQSTELLQAQAHVWNHIFNYVNSMSLKCATQLGIPDIIHRHGKPMTLEELVDVLHLNSAKAQAVYRLMRILTHLGFFVEEKVSEDDSNMGYWLTQASRLLLKDDALSSLPFLQVALDPLLIKPWHHMSEWFENNEDSSAFETAYGKTFWGYGSQEPKMNLLFKKAMASDTQLVSNVVTRDCKQVFQKLKSIVDVGGGTGSLAKAIVDSFPDLQCVVFDLPHVIAGLEGTKNLTYVGGNMFETIPRADALLLKVWSLFIRPTNKIETFTLFCN
>rna-XM_022994063.1
MEEKLKNCIEYITEYMNLATHEWKDVKENGQSSSDAGFTHYKIAHKLGYKSLIEVYPEWFENNEDSSAFETAYGKTFWDYGSQEPKMNLLFNKAMASDTQLVSNVVTRDCKQVFEKLKSIVDVGGGTGSLAKAIVDSFPDLQCVVFDLPHVIAGLEGTKNLTYVGGNMFETIPRADALLLKCILHDWSDEDCVKILKKCREAIPCKENGGKVIIIDIIVGNKKEDHKGIETQLFYDMSMMVWANGRERTEKEWAKLFFDAGFTRYNIVYGLGLRSIIEVYP
>rna-XM_022994272.1
MALPIGEQSTELLQAQAHVWNHIFNYVNSISLKCATQLGIPDIIHRHGKPMTVQELVDALHINSAKAQAVHRLMRILTHLGFFVEEKVSEDDSNMGYWLTQASRLLLKDDALSVLPSLQIALDPLLIKPWHHMSEWFENNEDSSAFETAYGRTFWDYGSQEPKMNQLFNKAIASDTQLVSNVVARDCKQVLEKLKSIVDVGGGTGSMAKAIVDSFPDLHCIVFDLPHVIAGLEGTKNLTYVGGNMFETIPRADALLLKCILHDWSDEDCVKILKKCREAIPCKENGGKVIIIDIIIGNKKEDHKGIGTELFYDMSMMIFANGRERIEKEWAKLFFDAGFTGYNIVYGLGLRSIIEVYP
>rna-XM_023001811.1
MAFLIGEQSAELLQAQAKFWNHEYNFIYIASLKCVTQLGIPDIIYKHGKPITLQQLADVLPINKAKVHGVYRLIRVLVHSGFFTKEKVSDDVANMGYWLTPASRLLIKDQSLSMIPVLEASFYPTYLKPWHHMSEWFQNDDLSAFETAHGSTLWDYASHDPKLNEFFNEHMVNDTELLSRIVIRDCQNVFDNMKSMVDVGGNTGFMAKAIADAFPHLHCAVFDLPHVVAGLKGSKNLTYIEGNMFESIPQADAVMLKWILHDWSDEESLKILKKCKEAIPSKENGGKVIIVDMIVRNNKEDHQQTETQLFYDLLMMVLINGKERTEKEWEELFFDAGYSGYKIAYELGLWSLIEVYP
>rna-XM_023007988.1
MAFLIGEQSVELLQAQAKFWNHEYNFIYIASLKCVTQLGIPDIIYKHGKPITLQQLANVLPINKAKVHGVYRLMRVLVHSGFFIKEKVSDDDADMGYWLTPASRLLIKDQALSMIPFLEASFYPTYLKPWHHMSEWFQNDDLSAFETAHGSTLWDYASHDPKLNELFNEHMVNDTESLSRIVIRDCQNVFHNMKSMVDVGGNTGFMAKAIADAFPHLHCTLFDLPHVVAGLTGSKNLTYIEGNMFESIPQADAVMLKWILHDWSDEESVKILKKCKVAIPSKENEGKVIIIDMIVRNNKEDHQETETQLFYDLLMMVLNNGKERTEKEWEEVFFDAGHSGYKIAYELGLWSLIEVYP
>rna-XM_023013933.1
FTAELLKAQAKFWNHIFTFPYMASLKCVTELGIPDIIHKHGKPMTLQQLGDALPINKAKVQGVYRLMRFLVHSGFFIEKKVSEDDTNMGYWLTPASQLLIKDQALSMIPFLQSCLNPIYVKPWNHITEWLQNDDHSAFKIAHGCTLWDYACRDPKFSQSLNEDLCDDTDMLSRIIIRDCKNVFDKINSMVDVGGNTGFMAKAIADAFPHLRCAVFDLPHIVEGLEGSYKNLTYIKGNMFESIPQADAIMLKWILHDWSDEECVQILKKCKEAIPRKENGGKVIIIDMIVGNNKEDHQHTETQIFNDLAMMVFLNGKERTEKEWEKLFLDAGYSGYKIAYDLGLRSLIELYP
>rna-XM_023018336.1
MTIIFGDSSKSAKRWLGYKVIDKIPNNYEHRFPVEPFAAKPTIGPRGWGVGVRALERVYIASQCPSTSTKFKQNGEQSTELLHAQAHIWNQIFNFINSMSLKCAIQLGIPDIIHKHGKPMTLPELVDALPIDKAKSQCVSRLMRILTHSRFFIDAKIFENEENMGYWLTSASRLLLKDEPLSVTPFLLAMLDPILTEPWHHLSEWFESDQNPTAFDTKHGRMFWEYAGREPRLNSFFNEAMASDARLVTSVLIRDCKHVFEGLNSIVDVGGGTGTLSKNIADAFPNLKCTVLDLPHVVAGLEGTKNLSYLGGDMFESIPSADAILLKWILHDWSDEECVKILKTCKEAIQSTDKEGKIIIIDMIIDNQKEDNKAIETQLHFDMLMMALLTGRERNEKEFATIFYDAGFTRYKIIPILGLRSVIEVYP
>rna-XM_023018337.1
MDIKGLLLLVLIQVNFFSRVIDPCATHNYEHRFPVEPFAAKPTIGPRGWGVGVRALERVYIASQCPSTSTKFKQNGEQSTELLHAQAHIWNQIFNFINSMSLKCAIQLGIPDIIHKHGKPMTLPELVDALPIDKAKSQCVSCLMRILTHSRFFIDAKISENEENMGYWLTSASRLLLKDEPLSVTPFLLAMLDPILTEPWHHLSEWFESDQNPTAFDTKHGRMFWEYAGHEPRLNSFFNEAMASDARLVTSVLIRDCKHVFEGLNSIVDVGGGTGTLSKNIADAFPNLKCTVLDLPHVVAGLEGTKNLSYLGGDMFESIPSADAILLKWILHDWSDEECVKILKTCKEAIQSTHKEGKIIIIDMIIDNQKEDNEAIETQLQFDMLMMAIVTGRERNEKEWATIFYDAGFTNYKIIPILGLRSVIEVYP
>rna-XM_023018322.1
MPLPNGEVQFSELLRAQSHVWNHIFNFINSISLKSAIQLGIPDIILKHGKPMTLPELVDILRINKAKAHGVYRLMRILIHSGFFIEEKISQNEEKKGYWLTSASRLLLKEEPFSLAPLLLVVLDPFLTEPWHYVAEWLKDDHPTPFSTLHGRSFWAYAGQDPKLNHLFNNAMANDSRLITSVVIRDCKHVFEGLNSIVDVAGGTGTMAKAIAETFPNLKCTVLDLPHVVAGLKGTKNLCYVGGDMFETIPNADAILLKWILHDWSDEECIKILKKCKEAIPSKEEGGKLIIIDMVVVDNQKEEEEIIESQLFFDMMMMVAVGGIEREEREWMKLLKASGFSHYKIINKLGSRSLIEVYPS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University