Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Olea europaea
Species name
Common olive (Olea europaea) is a species of eudicot in the family Oleaceae (olive famly).
Species info
Gene sequence info
Olea_europaea.4CL.fa
Download
>rna-XM_022985640.1
METKTMQEEIIFRSKLPDIYIPKHLPLHSYCFENISQFSSRPCLINGATNEVYTYAEVELISRKVASGLNKIGIQQGETIMILLPNSPEFVFAFLGASYRGALSTMANPFFKPAEVVKQAKASNAKLIITQGCYVEKVKEFALENGVKVMCIDEPPEGCLPFSDLTKADENNMPAADENNMPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPLVDKYDLSSVRTVMSGAAPLGRELEDAVRSKFAKAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDTETAASLGRNEPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGLIDADDELFIVDRLKEIIKYKGFQVAPAEIEALLLNHPNISDAAVVPMKDEEAGEVPVAFVVKSNASTISEDEIKQFVSKQVVFYKRVNRVFFIDAIPKSPSGKILRKDLRARLAVGVPN
>rna-XM_023026383.1
MLSVASVETQNSELSSLGSPQKPQTQSSEETHVFISKLPQIPISNHLPLHAYCFEDLAQYPDRPCLIMGNGGKTYSFSETHLVCRKTAAGLSILGVKKGDVIMVLLQNCAEFVFTFMGASMIGAVTTTANPFYTSSEIFKQFGASKAKLIITQSQYVCKLRDQGQDYPKLGEDFTVITIDDPPENCLHFSVLSEANENDIPSVCVDPNDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKSDDVVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGSLLELIQRHRVSVAAVVPPLVLALAKNPMVDKFDLSSIRVVLSGAAPLGKDLETALRNRVPQAIFGQGYGMTEAGPVLSMSPAFAKQPMPTKSGSCGNVVRNAELKVVDPESGSSLPRNQPGEICIRGPQIMKGYLNDVEATANTIDVDGWLHTGDVGYVDDDDDVFIVDRVKELIKFKGFQVPPAELEALLVSHPNIADAAVVPQKDEAAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHKVYFIHSIPKSPAGKILRKDLRAKLTTTSS
>rna-XM_023028373.1
MESGAQSIMQDEIIFRSNYPPVQVPEDLTLPEFVLSNAEPYLDKVAFVDELTGKEYNYGEVTRDVKRFANALRSLGLRKGRVVVVVLPNVAEYAIIALGIMAACGVFSGANPNAHSSEIKKQVETADAKIIVTDGSTYDKVKDLGLPVIIQGDDRIEGTIYWDELLEAADRANTGIIEEKVHQNDLCALPFSSGTTGLSKGVMLTHRNLVANLCSSLFSVGPELIGQVTILGLIPFFHIYGLTGICCATIRNKGKVVVMRRYELRAFVSALITHQITFAPIVPPIILVLVKNPIVDEFDLRKLKLRSVMTAAAPLAPEILTEFEKKFPGVQVQEAYGMTEHSCITLTHGNPNKGHGIAKRNSVGFILPNLEVKFIDPEMGRSLPKNSPGEICVRSQCVMKGYYKNDYETALTIDKEGWLHTGDIGYIDDDGDVFLVDRIKELIKYKGFQVAPAELEAILLSHHSVEDAAVVGLPDKEAGEIPAACVVISSKEKESEEDIMNFVASNVATYKRIRMLQFVDTIPKSPSGKIMRRVVKENMVKNL
>rna-XM_023033966.1
METKKMQEETIFRSKLPDIYIPKHLPLHSYCFENISQFSSRPCLINGATDEVYTYTEVELISRKVASGLNKIGIQQGETIMILLPNSPEFVFAFLGASYRGALSTMANPFFKPAEVVKQAKASNAKLIITQGCYVEKVKEYALENCVKVMCIDEAPEGCLPFSDLTKADENDMPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGSAILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPLVDKYDLSSIRMVMSGAAPLGRELEDAVRSKFSKAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDTETGASLLRNDRGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGFIDADDELFIVDRLKEIIKYKGFQVAPAEIEALLLNHPKISDAAVVPMKDEEAGEVPVAFVVKSNGSNITEDEIKQFVSKQVIFYKRVNRVFFIDAIPKSPSGKILRKDLRARLAAGVPN
>rna-XM_023040999.1
MLSVASVETQNSELSSIASPQKPQIQSSDETHVFISKLPQIPISNHLPLHTYCFENLAQYPERPCLIVGSTGKTYSFSETHLLCQKTAAGLSNLGVKKGDVIMVLLQNCPEFVFTFIGASMIGAITTTANPFYTSSEVFKQLGASKAKLIITQSQYVDKLRDPGQNNPKVGEDFTVITIDDPPENCLHFSVLSEANENDIPSISIDPNDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKSDDVVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGSFLELIQRHRVSVAAVVPPLVLALAKNPMVDKFDLSSIRVVLSGAAPLGKELEAALRNRVPQAIFGQGYGMTEAGPVLSMSPAFAKQPILTKSGSCGNVVRNAELKVVDPESGTSLPRNQPGEICIRGPQIMKGYLNDAEATANTIDVDGWLHTGDIGYVDDDDNVFIVDRVKELIKFKGFQVPPAELEALLISHPNIADAAVVPQKDEAAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHKVYFIHAIPKSPAGKILRKDLRAKLATTTTSS
>rna-XM_022987920.1
MENGAETIAQDEIIFRSKYPSVQVPEDLTLPEFVLSNAEQYLDKVAFVDALTGKGYNYGEVTRDIKRFANALRSLGLRKGRVVVVVLPNVAEYAVIALGIMAAGGVFSGANPNAHSSEIKKQVEAADAKLIVTDGSTYDKVKDLGLPVIIQGEDRVEGTIYWDELLEAADRATTGIVEEKVHQNDLCALPFSSGTTGLSKGVMLTHRNIVANLCSTLFSVGPELIGQVTILGLIPFFHIYGLTGICCASIRNKGRVVVMRRYELRAFMSALIIHQIMFAPIVPPIILELVKNPIVDEFDLTKLKLGSVMTAAAPLAPEILTEFEKKFPGVEVQEAYGMTEHSCITLTHGDPNKGHGIAKRNSVGFILPNLEVKFIDPEKGRSLPKNSPGEICVRSQCVMKGYYKNEYETTLTIDKEGWLHTGDIGYIDDDGDVFLVDRIKELIKYKGFQVAPAELEAILLSHHSVEDAAVVGLPDKEAGEIPAACVVVSLKAKENEEDIMNFVASNVATYKRIRILQFVDMIPKSPSGKIMRRLVKENMVKILQTNTKG
>rna-XM_023006390.1
MEKSGYGRDGIYRSLRPPLVLPKDPNLSMVSFLFRNISSFPDKPALIDFHTGQTLTFIEFKSVVSKVSYGLLQLGIKKKDVVLIYSPNSIQFPICVFGIVGIGAIATTVNPIYTVSELSKQVHDCKPKVIITVQELLPKVKDFNLPVILLGTDKKPLEPIGKIPSIKLFTELVNNEGSVDLDNRIKQNDTAVLLYSSGTTGTSKGVILSHRNFIAASLMVTADQEWAGEINNVFLCVLPMFHVFGLAVIMYSQLQRGNSVVSMAKFDFEMILKAIEKYKVTHLWVVPPIMLALAKNSVIKKYDLSSLKQIGSGAAPLGTDLMKECAKNFPQAIVLQVKFLSQFFFSFGSGYFNNPQATRLTIDKQGWVHTGDIGYFDEDGQLYVVDRIKELIKYKGFQVSYS
>rna-XM_023009054.1
MKEYLNNVAATMATIDEDGWLHTGDIVCFDQEGYLYVLDRLKEFIKYKGFQIAPADLESVLLSHPEVLDAAVTAAKDEEAGEIPIAFVVRKDGSSLSDTALMDYVAKQVTPYKKVRKVFFRTSIPRSAAGKILRRELRALINSKL
>rna-XM_023009687.1
MDTKTKQEDIRFRSKLPDIYIPKHLPLHSYCFENISKYSTKPCLINGTSGEVYTYEEVELTARKVASGLNNLGIRQGDTIMLLLPNSPEFVFAFIGSSFSGAVSTMANPFFTAAEVVKQAKASKAKLIITQACYLDKVRNYAEENAVKVMCIDTPAPEGCLLFSELTKADEKDMLAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSDDVILCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEILPFLELIQKYKVTIGPFVPPIILAIAKSPAVGKYDLSSVRTVMSGAAPLGKELEDAVRMKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFVIKSGACGTVVRNAKMKIVDTETGASLGRNQTGEICIRGDQIMKGYLNDPEASERTIDKEGWLHTGDIGFIDADDELFIVDRLKEIIKYKGFQVAPAEIEALLHNHPNISDAAVVPMEDEQAGEVPIAFVVISNGSSITEDEIKQFISKQVIFYKRINRVFFIDAIPKSPSGKILRKDLRARLAVGVPN
>rna-XM_023011859.1
MQRSRNTATPPPSAAASLPPHSKMSLNKDKEEFIFRSKLPDIYIPNHLPIHTYCFQNISKHSTRPCIINAANGEVFSQADVKLTAGKVAAGLNKLGIQQGQVIMLLLHNSPEFVFAFLGASYIGAITTTANPLYTPAEIEKQATISKPYLIITHAIYVQKVKNFAQQNGVKIFCIDPPPESCFHFSELTQTDENSIPSVNVHPDDMVVLPFSSGTTGFPKGVMLTHKNLVTCVSQQVDGENPTLCVQPEDLTICVLPLFHVYSLITVMLCTLRVGSAILIMQKFEINALMENVQKYKVTIAPFVPPILLAIAKSPVADRFDLSSVRRVVCGAAPMDKNLEDAVRRKLPNAKIGQGYGMTEGGVVSMCLGFAKEAFQFKSGSCGTVIRNAQMKINDPQTGLSLPYNRAGEIWIRGDQIMKGYLNDPEATKRTIDREGWMHTGDIGYVDENEELFIVDRLKELIKYKGFHIAPAELEALLIVHPSISDAAVVPMNDDAAGEVPVAFVVRENGSKISEEHIKQYISTQVVPYKRINRVFFIDEIPKAPSGKIIRKILRARI
METKTMQEEIIFRSKLPDIYIPKHLPLHSYCFENISQFSSRPCLINGATNEVYTYAEVELISRKVASGLNKIGIQQGETIMILLPNSPEFVFAFLGASYRGALSTMANPFFKPAEVVKQAKASNAKLIITQGCYVEKVKEFALENGVKVMCIDEPPEGCLPFSDLTKADENNMPAADENNMPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPLVDKYDLSSVRTVMSGAAPLGRELEDAVRSKFAKAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDTETAASLGRNEPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGLIDADDELFIVDRLKEIIKYKGFQVAPAEIEALLLNHPNISDAAVVPMKDEEAGEVPVAFVVKSNASTISEDEIKQFVSKQVVFYKRVNRVFFIDAIPKSPSGKILRKDLRARLAVGVPN
>rna-XM_023026383.1
MLSVASVETQNSELSSLGSPQKPQTQSSEETHVFISKLPQIPISNHLPLHAYCFEDLAQYPDRPCLIMGNGGKTYSFSETHLVCRKTAAGLSILGVKKGDVIMVLLQNCAEFVFTFMGASMIGAVTTTANPFYTSSEIFKQFGASKAKLIITQSQYVCKLRDQGQDYPKLGEDFTVITIDDPPENCLHFSVLSEANENDIPSVCVDPNDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKSDDVVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGSLLELIQRHRVSVAAVVPPLVLALAKNPMVDKFDLSSIRVVLSGAAPLGKDLETALRNRVPQAIFGQGYGMTEAGPVLSMSPAFAKQPMPTKSGSCGNVVRNAELKVVDPESGSSLPRNQPGEICIRGPQIMKGYLNDVEATANTIDVDGWLHTGDVGYVDDDDDVFIVDRVKELIKFKGFQVPPAELEALLVSHPNIADAAVVPQKDEAAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHKVYFIHSIPKSPAGKILRKDLRAKLTTTSS
>rna-XM_023028373.1
MESGAQSIMQDEIIFRSNYPPVQVPEDLTLPEFVLSNAEPYLDKVAFVDELTGKEYNYGEVTRDVKRFANALRSLGLRKGRVVVVVLPNVAEYAIIALGIMAACGVFSGANPNAHSSEIKKQVETADAKIIVTDGSTYDKVKDLGLPVIIQGDDRIEGTIYWDELLEAADRANTGIIEEKVHQNDLCALPFSSGTTGLSKGVMLTHRNLVANLCSSLFSVGPELIGQVTILGLIPFFHIYGLTGICCATIRNKGKVVVMRRYELRAFVSALITHQITFAPIVPPIILVLVKNPIVDEFDLRKLKLRSVMTAAAPLAPEILTEFEKKFPGVQVQEAYGMTEHSCITLTHGNPNKGHGIAKRNSVGFILPNLEVKFIDPEMGRSLPKNSPGEICVRSQCVMKGYYKNDYETALTIDKEGWLHTGDIGYIDDDGDVFLVDRIKELIKYKGFQVAPAELEAILLSHHSVEDAAVVGLPDKEAGEIPAACVVISSKEKESEEDIMNFVASNVATYKRIRMLQFVDTIPKSPSGKIMRRVVKENMVKNL
>rna-XM_023033966.1
METKKMQEETIFRSKLPDIYIPKHLPLHSYCFENISQFSSRPCLINGATDEVYTYTEVELISRKVASGLNKIGIQQGETIMILLPNSPEFVFAFLGASYRGALSTMANPFFKPAEVVKQAKASNAKLIITQGCYVEKVKEYALENCVKVMCIDEAPEGCLPFSDLTKADENDMPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGSAILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPLVDKYDLSSIRMVMSGAAPLGRELEDAVRSKFSKAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDTETGASLLRNDRGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGFIDADDELFIVDRLKEIIKYKGFQVAPAEIEALLLNHPKISDAAVVPMKDEEAGEVPVAFVVKSNGSNITEDEIKQFVSKQVIFYKRVNRVFFIDAIPKSPSGKILRKDLRARLAAGVPN
>rna-XM_023040999.1
MLSVASVETQNSELSSIASPQKPQIQSSDETHVFISKLPQIPISNHLPLHTYCFENLAQYPERPCLIVGSTGKTYSFSETHLLCQKTAAGLSNLGVKKGDVIMVLLQNCPEFVFTFIGASMIGAITTTANPFYTSSEVFKQLGASKAKLIITQSQYVDKLRDPGQNNPKVGEDFTVITIDDPPENCLHFSVLSEANENDIPSISIDPNDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKSDDVVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGSFLELIQRHRVSVAAVVPPLVLALAKNPMVDKFDLSSIRVVLSGAAPLGKELEAALRNRVPQAIFGQGYGMTEAGPVLSMSPAFAKQPILTKSGSCGNVVRNAELKVVDPESGTSLPRNQPGEICIRGPQIMKGYLNDAEATANTIDVDGWLHTGDIGYVDDDDNVFIVDRVKELIKFKGFQVPPAELEALLISHPNIADAAVVPQKDEAAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHKVYFIHAIPKSPAGKILRKDLRAKLATTTTSS
>rna-XM_022987920.1
MENGAETIAQDEIIFRSKYPSVQVPEDLTLPEFVLSNAEQYLDKVAFVDALTGKGYNYGEVTRDIKRFANALRSLGLRKGRVVVVVLPNVAEYAVIALGIMAAGGVFSGANPNAHSSEIKKQVEAADAKLIVTDGSTYDKVKDLGLPVIIQGEDRVEGTIYWDELLEAADRATTGIVEEKVHQNDLCALPFSSGTTGLSKGVMLTHRNIVANLCSTLFSVGPELIGQVTILGLIPFFHIYGLTGICCASIRNKGRVVVMRRYELRAFMSALIIHQIMFAPIVPPIILELVKNPIVDEFDLTKLKLGSVMTAAAPLAPEILTEFEKKFPGVEVQEAYGMTEHSCITLTHGDPNKGHGIAKRNSVGFILPNLEVKFIDPEKGRSLPKNSPGEICVRSQCVMKGYYKNEYETTLTIDKEGWLHTGDIGYIDDDGDVFLVDRIKELIKYKGFQVAPAELEAILLSHHSVEDAAVVGLPDKEAGEIPAACVVVSLKAKENEEDIMNFVASNVATYKRIRILQFVDMIPKSPSGKIMRRLVKENMVKILQTNTKG
>rna-XM_023006390.1
MEKSGYGRDGIYRSLRPPLVLPKDPNLSMVSFLFRNISSFPDKPALIDFHTGQTLTFIEFKSVVSKVSYGLLQLGIKKKDVVLIYSPNSIQFPICVFGIVGIGAIATTVNPIYTVSELSKQVHDCKPKVIITVQELLPKVKDFNLPVILLGTDKKPLEPIGKIPSIKLFTELVNNEGSVDLDNRIKQNDTAVLLYSSGTTGTSKGVILSHRNFIAASLMVTADQEWAGEINNVFLCVLPMFHVFGLAVIMYSQLQRGNSVVSMAKFDFEMILKAIEKYKVTHLWVVPPIMLALAKNSVIKKYDLSSLKQIGSGAAPLGTDLMKECAKNFPQAIVLQVKFLSQFFFSFGSGYFNNPQATRLTIDKQGWVHTGDIGYFDEDGQLYVVDRIKELIKYKGFQVSYS
>rna-XM_023009054.1
MKEYLNNVAATMATIDEDGWLHTGDIVCFDQEGYLYVLDRLKEFIKYKGFQIAPADLESVLLSHPEVLDAAVTAAKDEEAGEIPIAFVVRKDGSSLSDTALMDYVAKQVTPYKKVRKVFFRTSIPRSAAGKILRRELRALINSKL
>rna-XM_023009687.1
MDTKTKQEDIRFRSKLPDIYIPKHLPLHSYCFENISKYSTKPCLINGTSGEVYTYEEVELTARKVASGLNNLGIRQGDTIMLLLPNSPEFVFAFIGSSFSGAVSTMANPFFTAAEVVKQAKASKAKLIITQACYLDKVRNYAEENAVKVMCIDTPAPEGCLLFSELTKADEKDMLAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSDDVILCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEILPFLELIQKYKVTIGPFVPPIILAIAKSPAVGKYDLSSVRTVMSGAAPLGKELEDAVRMKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFVIKSGACGTVVRNAKMKIVDTETGASLGRNQTGEICIRGDQIMKGYLNDPEASERTIDKEGWLHTGDIGFIDADDELFIVDRLKEIIKYKGFQVAPAEIEALLHNHPNISDAAVVPMEDEQAGEVPIAFVVISNGSSITEDEIKQFISKQVIFYKRINRVFFIDAIPKSPSGKILRKDLRARLAVGVPN
>rna-XM_023011859.1
MQRSRNTATPPPSAAASLPPHSKMSLNKDKEEFIFRSKLPDIYIPNHLPIHTYCFQNISKHSTRPCIINAANGEVFSQADVKLTAGKVAAGLNKLGIQQGQVIMLLLHNSPEFVFAFLGASYIGAITTTANPLYTPAEIEKQATISKPYLIITHAIYVQKVKNFAQQNGVKIFCIDPPPESCFHFSELTQTDENSIPSVNVHPDDMVVLPFSSGTTGFPKGVMLTHKNLVTCVSQQVDGENPTLCVQPEDLTICVLPLFHVYSLITVMLCTLRVGSAILIMQKFEINALMENVQKYKVTIAPFVPPILLAIAKSPVADRFDLSSVRRVVCGAAPMDKNLEDAVRRKLPNAKIGQGYGMTEGGVVSMCLGFAKEAFQFKSGSCGTVIRNAQMKINDPQTGLSLPYNRAGEIWIRGDQIMKGYLNDPEATKRTIDREGWMHTGDIGYVDENEELFIVDRLKELIKYKGFHIAPAELEALLIVHPSISDAAVVPMNDDAAGEVPVAFVVRENGSKISEEHIKQYISTQVVPYKRINRVFFIDEIPKAPSGKIIRKILRARI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University