Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Nissolia schottii
Species name
Nissolia schottii is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Nissolia_schottii.4CL.fa
Download
>Nissc528534S28473
MLSVAPSVEQSPERSASKNANSNDQKQQSPETTHIFRSKLPEIPISNHLPLHSYCFERLSEFSDRPCLIVGSASKTYTYAETYLLSRRVAAGLSAIGVKKGDVIMILLQNSAEFVLSFLAASMIGAVATTANPFYTSAEIFKQISTSKSKIVITQAMYVDKLRDHNDTAAAAVPKIGEDFKVITVDDPPANCLHFSVISEGNENDLPEVDINPDDAVALPFSSGTTGLPKGVVLTHKSLTTSVAQQVDGENPNLYLKTEDVLLCVLPLFHIFSLNSVLLCALRAGSAVLLMQKFEIGALLELIQRYKVSVAMVVPPLVLALAKNPMVADYDLSSIRLVLSGAAPLGKELEEALGSRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDSETGLSLGYNQPGEICIRGQQIMKGYLNDDKATATTIDVEGWLHTGDVGYIDDDDEIFIVDRVKELIKFKGFQVPPAELEGLLVSHPSIADAAVVPQKDVAAGEVPVAFVVRSNGFDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLESANQNP
>Nissc2738S20003
MTEACGLISLEGAEEGGTCRLSGSTGKLKPTIEAQIVSLQTLNPLPPNQVGEICLRGPTMMQGYYNNPEATKMAINDQGWMRTENLGYFDEDGQLFVVDRNKELIKCNGYQVGPAEQIKDAGVIPSPDAKAGEVPVVYVVLSPNSSLKEEQIQKFVVEQVAPYKRLRRVNFIDKIPRAAAGKILRGYIIALDRQRTSKL
>Nissc9492S11698
MGTCMENVARGDQEEHIFRSQYEPVPVPDNVTLPEFVLQQAELYADKVAFVDAVTEKKITYSEVVRDTHRFSRALRSVGLRKGHVVVVVLPNVAEYAIVALGIMAAGGVFSGANPASHVSEIKKQAESADAKLLVTNGSNYEKVKGLELPVIVLDELVGGAMNWNKLLEAADRAGDDSKKEPIQQSDLCAMPFSSGTTGLSKGVMLTHRNLIANLCSTLFGVSPEMVGQVTTLGLIPFFHIYGITGICCATLKNKGKVVVMGRFELKAFINALIKHEVNFAPIVPPIILSLVKNPIVDEFDLSKLKLQAVMTAAAPLAPELLTAFEHKFPGVLVQEAYGLTEHSCITLTHAQKAPGVLHKNSVGFILPNLEVKFIDPDTGKSLPRNAPGELCVRSQCVMQGDGDTICPQKSHDDCDHLHHDPFNIVSVDETAQTIDNNGWLHTGDIGFIDDEDNVYIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVVPLPDEEAGEIPAASVVLSPGATESVEDIMNYVASNAAHYKKVRVVHFVEAIPKSPSGKIMRRLIKEKMVEKMKKTNPSMKSNT
>Nissc524662S27528
MQRSGYCSDGIYRSLRPSLSLPKDPNLSLVSHLFSNVGPFPTKPALIDADTSQSLSFSHLRSLVIKASHGLLRLGLSKSDVVLFLSPNTIYYPVCFLAVTAIGAVASTVNPAYTPAEVSKQLKDSNPKLIITVPELYDKVKTFNLPAVFLNSDPAVHVARSGSKIASFEELVNLAGSPTEFPAISVKQSDTAALLYSSGTTGVSKGVVLTHRNFIAAGMMIGMDDEVAGQFGDVFLCVLPMFHVFGLAVISYSQLQRGNAVVSLKRFEFEVVLKTIERYKVTRLWVVPPIILALAKHGLVDKYDLSSLAQIGSGAAPLGKELMDECSKRFPHAIVCQGYGMTETCGIVSVEDVRAGVRNTGSTGMLVSGVEAQIVSVETQKPQPPRQLGEIWVRGPNMMQGYHNNPQATRLTIDKSGWVHTGDLGYFDEEGHLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEEDVKKFIANQVAPFKRLRRVTFINTVPKTASGKILRRELIDKARSRI
>Nissc300S20872
MEQKNDHKEFIFRSKLPDIYIPTHLPLHTYCFENLSKFKDRPCLINAATGETFTYAAVELTARKVAAGLNNIGIDQGDVIFILLQNCHHFVFAFLGASYRGATVTTGNPFYTPAEVAKQAIASNAKLIITQSSFVDKVKDLAREREIKLMCIDAPAPQAEYLQFSELTEADEGEIPAVKISPDDAVALPFSSGTTGLPKGVMLSHKGLVTSVAQQVDGENPNLDFHQNDVLLCVLPLFHVYSLSSTLLCGLRVGAAILIMQKFEIVTLLEMVQKHRVSVAPFVPPIVLALAKSSEVDRYDLSSIRLVMSGAAPMGKELEDAVKAKLPNATTGQGYGMTEAGPVLSMSLAFAKEPFEVKSGACGTVVRNAEMKIIDTDTGASLPRNHAGEICIRGNQIMKGYLNDPKATERTIDKERWLHTGDIGYIDDNDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVAMRDEAAGEVPVAYVVRSSSSKISEDEIKQYISKQWANHLGQTHNIYSFSCLSLSKMEPQPTAQDELIFRSKLPDIPIPTHLPLHSYCFQNLPLFRHRPCLIDADTGHTLSHSDVHLATRRISAGLHSIGIRKGDVIMLLLRNCHQFALAFLGASHRGAAVTTANPFYTSSELAKQVSATKSKLIITQSAYVEKIKDFADSNGVMIMCIDCSEEKEGALNFSALMQADENDAPEVDITPDDVVAIPFSSGTSGLPKGVMLTHKNLVTTVAQLVDGENPHQYTHSEDVLLCVLPMFHIYALNSILLCGIRAGAAVLIVQKFEIATLLELVHKYRVTVASLVPPIILALVKCGDVHRYDLSSIRAVITGAAPMGVELQDAVKARLPHATLGQGYGMTEAGPLAISLAFAKEPFKIKSGACGTVVRNAEMKIVDTETGVSLPQKKAGEICIRGTKVMKGYLNDPEATKRTIDKDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPNISDAAVVPMKDEAAGEVPVAFVVRSNGSKITEDEIKQYISQQVVFYKRINSVFFTDAIPKAASGKILRKDLSAKLNEGLVVAN
>Nissc14013S14600
MQRSGYGSDGTYRSLRPPLHLPKHPSLTSFLFQSTAPFLSKPALLDARTSQSLTFGDLKTTVATLSHALLRLGLAKNDAVLLFAPNSIQFPLCFLAAAAIGAVVTTANPLYTSAELSKQIKDSNPKLLITVPELWEKVRAFKFELPAIFIDSESSDQGEAGKTKEDFMSFGRLMELAGSSFTELPENDVRQGDTAALLYSSGTTGVSKGVVLTHGNFMAAALMIGMDDDVAGDVEESVLLCVLPMFHVFGLAVIVYSQLRRGSTVVSMGGRFELEKFLEAVERHKVTNLWVVPPIVLAMAKQSVVERYDLSSLKRIGSGAAPLGKELMEDCARRFPHAAVMQGYGMTETCGIISVENPRVGTRHTGSAGMLASGVQARIVSVDAHKPLPPTHLGEIWVRGPNIMKGYHNNPQATRLTVDNNGWLHTGDLGYFDDHGHLYVVDRIKELIKYKGLQVAPAELEGLLVSHPDILDAVVVPYPDDEAGEVPIAYVVPSPDSSLTEEDVQKFIANQVAPYKKLRKVTFISSVPKTASGKILRRELIGKVRSKI
>Nissc1056S12596
MAIEKEEKKQSPPQKQELIFRSKLPDIYIPNHLPLHSYCFQNLAEFGSRPCLINAPTGETFTYADVELTARRIAAGLNRIGIQQGDVIMILLPNSPQFVFAFLGASFRGATATACNPFFTAAEIAKQAKASNAKLIVTQACYYDKVKELDHVRLVFVDSPPPQAEGHLHFSELDGAEEKEIIPEVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSIAQQVDGENPNLYFHSEDVIMCVLPLFHIYSLNSVLLCGLRAKAAILLMPKFDITAFLGLVQKHRVTICPVVPPIVLAIAKSPELDKYDLSSIRVLKSGGAPLGKDLEDNVRAKFPKAKLGQGYGMTEAGPVLTMCLTFAKEPIDGKPGACGTVVRNAEMKIVDPETENSLPRNQPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALILSHPKISDVAVVPMKDEAAGEVPVAFVVRSNGHTDTTEDEIKQFVSKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRARLAAGVPN
MLSVAPSVEQSPERSASKNANSNDQKQQSPETTHIFRSKLPEIPISNHLPLHSYCFERLSEFSDRPCLIVGSASKTYTYAETYLLSRRVAAGLSAIGVKKGDVIMILLQNSAEFVLSFLAASMIGAVATTANPFYTSAEIFKQISTSKSKIVITQAMYVDKLRDHNDTAAAAVPKIGEDFKVITVDDPPANCLHFSVISEGNENDLPEVDINPDDAVALPFSSGTTGLPKGVVLTHKSLTTSVAQQVDGENPNLYLKTEDVLLCVLPLFHIFSLNSVLLCALRAGSAVLLMQKFEIGALLELIQRYKVSVAMVVPPLVLALAKNPMVADYDLSSIRLVLSGAAPLGKELEEALGSRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDSETGLSLGYNQPGEICIRGQQIMKGYLNDDKATATTIDVEGWLHTGDVGYIDDDDEIFIVDRVKELIKFKGFQVPPAELEGLLVSHPSIADAAVVPQKDVAAGEVPVAFVVRSNGFDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLESANQNP
>Nissc2738S20003
MTEACGLISLEGAEEGGTCRLSGSTGKLKPTIEAQIVSLQTLNPLPPNQVGEICLRGPTMMQGYYNNPEATKMAINDQGWMRTENLGYFDEDGQLFVVDRNKELIKCNGYQVGPAEQIKDAGVIPSPDAKAGEVPVVYVVLSPNSSLKEEQIQKFVVEQVAPYKRLRRVNFIDKIPRAAAGKILRGYIIALDRQRTSKL
>Nissc9492S11698
MGTCMENVARGDQEEHIFRSQYEPVPVPDNVTLPEFVLQQAELYADKVAFVDAVTEKKITYSEVVRDTHRFSRALRSVGLRKGHVVVVVLPNVAEYAIVALGIMAAGGVFSGANPASHVSEIKKQAESADAKLLVTNGSNYEKVKGLELPVIVLDELVGGAMNWNKLLEAADRAGDDSKKEPIQQSDLCAMPFSSGTTGLSKGVMLTHRNLIANLCSTLFGVSPEMVGQVTTLGLIPFFHIYGITGICCATLKNKGKVVVMGRFELKAFINALIKHEVNFAPIVPPIILSLVKNPIVDEFDLSKLKLQAVMTAAAPLAPELLTAFEHKFPGVLVQEAYGLTEHSCITLTHAQKAPGVLHKNSVGFILPNLEVKFIDPDTGKSLPRNAPGELCVRSQCVMQGDGDTICPQKSHDDCDHLHHDPFNIVSVDETAQTIDNNGWLHTGDIGFIDDEDNVYIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVVPLPDEEAGEIPAASVVLSPGATESVEDIMNYVASNAAHYKKVRVVHFVEAIPKSPSGKIMRRLIKEKMVEKMKKTNPSMKSNT
>Nissc524662S27528
MQRSGYCSDGIYRSLRPSLSLPKDPNLSLVSHLFSNVGPFPTKPALIDADTSQSLSFSHLRSLVIKASHGLLRLGLSKSDVVLFLSPNTIYYPVCFLAVTAIGAVASTVNPAYTPAEVSKQLKDSNPKLIITVPELYDKVKTFNLPAVFLNSDPAVHVARSGSKIASFEELVNLAGSPTEFPAISVKQSDTAALLYSSGTTGVSKGVVLTHRNFIAAGMMIGMDDEVAGQFGDVFLCVLPMFHVFGLAVISYSQLQRGNAVVSLKRFEFEVVLKTIERYKVTRLWVVPPIILALAKHGLVDKYDLSSLAQIGSGAAPLGKELMDECSKRFPHAIVCQGYGMTETCGIVSVEDVRAGVRNTGSTGMLVSGVEAQIVSVETQKPQPPRQLGEIWVRGPNMMQGYHNNPQATRLTIDKSGWVHTGDLGYFDEEGHLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEEDVKKFIANQVAPFKRLRRVTFINTVPKTASGKILRRELIDKARSRI
>Nissc300S20872
MEQKNDHKEFIFRSKLPDIYIPTHLPLHTYCFENLSKFKDRPCLINAATGETFTYAAVELTARKVAAGLNNIGIDQGDVIFILLQNCHHFVFAFLGASYRGATVTTGNPFYTPAEVAKQAIASNAKLIITQSSFVDKVKDLAREREIKLMCIDAPAPQAEYLQFSELTEADEGEIPAVKISPDDAVALPFSSGTTGLPKGVMLSHKGLVTSVAQQVDGENPNLDFHQNDVLLCVLPLFHVYSLSSTLLCGLRVGAAILIMQKFEIVTLLEMVQKHRVSVAPFVPPIVLALAKSSEVDRYDLSSIRLVMSGAAPMGKELEDAVKAKLPNATTGQGYGMTEAGPVLSMSLAFAKEPFEVKSGACGTVVRNAEMKIIDTDTGASLPRNHAGEICIRGNQIMKGYLNDPKATERTIDKERWLHTGDIGYIDDNDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVAMRDEAAGEVPVAYVVRSSSSKISEDEIKQYISKQWANHLGQTHNIYSFSCLSLSKMEPQPTAQDELIFRSKLPDIPIPTHLPLHSYCFQNLPLFRHRPCLIDADTGHTLSHSDVHLATRRISAGLHSIGIRKGDVIMLLLRNCHQFALAFLGASHRGAAVTTANPFYTSSELAKQVSATKSKLIITQSAYVEKIKDFADSNGVMIMCIDCSEEKEGALNFSALMQADENDAPEVDITPDDVVAIPFSSGTSGLPKGVMLTHKNLVTTVAQLVDGENPHQYTHSEDVLLCVLPMFHIYALNSILLCGIRAGAAVLIVQKFEIATLLELVHKYRVTVASLVPPIILALVKCGDVHRYDLSSIRAVITGAAPMGVELQDAVKARLPHATLGQGYGMTEAGPLAISLAFAKEPFKIKSGACGTVVRNAEMKIVDTETGVSLPQKKAGEICIRGTKVMKGYLNDPEATKRTIDKDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPNISDAAVVPMKDEAAGEVPVAFVVRSNGSKITEDEIKQYISQQVVFYKRINSVFFTDAIPKAASGKILRKDLSAKLNEGLVVAN
>Nissc14013S14600
MQRSGYGSDGTYRSLRPPLHLPKHPSLTSFLFQSTAPFLSKPALLDARTSQSLTFGDLKTTVATLSHALLRLGLAKNDAVLLFAPNSIQFPLCFLAAAAIGAVVTTANPLYTSAELSKQIKDSNPKLLITVPELWEKVRAFKFELPAIFIDSESSDQGEAGKTKEDFMSFGRLMELAGSSFTELPENDVRQGDTAALLYSSGTTGVSKGVVLTHGNFMAAALMIGMDDDVAGDVEESVLLCVLPMFHVFGLAVIVYSQLRRGSTVVSMGGRFELEKFLEAVERHKVTNLWVVPPIVLAMAKQSVVERYDLSSLKRIGSGAAPLGKELMEDCARRFPHAAVMQGYGMTETCGIISVENPRVGTRHTGSAGMLASGVQARIVSVDAHKPLPPTHLGEIWVRGPNIMKGYHNNPQATRLTVDNNGWLHTGDLGYFDDHGHLYVVDRIKELIKYKGLQVAPAELEGLLVSHPDILDAVVVPYPDDEAGEVPIAYVVPSPDSSLTEEDVQKFIANQVAPYKKLRKVTFISSVPKTASGKILRRELIGKVRSKI
>Nissc1056S12596
MAIEKEEKKQSPPQKQELIFRSKLPDIYIPNHLPLHSYCFQNLAEFGSRPCLINAPTGETFTYADVELTARRIAAGLNRIGIQQGDVIMILLPNSPQFVFAFLGASFRGATATACNPFFTAAEIAKQAKASNAKLIVTQACYYDKVKELDHVRLVFVDSPPPQAEGHLHFSELDGAEEKEIIPEVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSIAQQVDGENPNLYFHSEDVIMCVLPLFHIYSLNSVLLCGLRAKAAILLMPKFDITAFLGLVQKHRVTICPVVPPIVLAIAKSPELDKYDLSSIRVLKSGGAPLGKDLEDNVRAKFPKAKLGQGYGMTEAGPVLTMCLTFAKEPIDGKPGACGTVVRNAEMKIVDPETENSLPRNQPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALILSHPKISDVAVVPMKDEAAGEVPVAFVVRSNGHTDTTEDEIKQFVSKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRARLAAGVPN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University