Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Nicotiana attenuata
Species name
Nicotiana attenuata is a species of eudicot in the family Solanaceae (nightshade family).
Species info
Gene sequence info
Nicotiana_attenuata.OMT.fa
Download
>rna-XM_019406212.1
MGEETNGVARIHEVDKAESQAQEDIWKYMFGFSEMAAVKCAIELGIPDLLENNQEAITLNQLSSALGCSCSNFLYRILRFLINRGIFKEESTGHGEIGYVQTPLSRLLRKDGENSMAALVLLEASPVMLAPWHFLSARALAKGNTAAFSAVHGKDVWEYAETNPEHSKLINDGLACHARVAIRAIIDSCPEIFKGIETLVDVGGGDGTTISLLVKTFPWISGINFDLPHVVSVAPHCHGVQHVAGNMFDSIPKADAAFLMSVLHDWSEDECIQILKNCIKIIPKDTGKVIMVEVVLEKEKGEGNEKLKDVGFMLDMVMMAHTTNGKERTAKEWAQILTAAGFSSHSIKHINAIESVILAYP
>rna-XM_019393499.1
MAKKENNRADHEQLLQAEAQTWDCILSFVRPYCITCAVELGIPDILHKNGIMTISDLVASLPNLNPSKISFLPILMRILVHSGLLHYQKEVDGYSVTSAGSLLVENEPFSKRSNFLFSQNPIALKPFFSLSHWLQDDLPTAFDTTYGKSMWDYCAEEPKFGHIFNDAMASDSKLISHLLINSEQCKHVFEGLTSLVDVGGGTGTVAMAIANAFPRLNCIVLDLPHVIGDRKGITTGNLEFVAGSMFDSIPYANAILLKFILHNWSDEDCVKLLRKCRESIPSKEKGGKVIVIDIVMEDYSSNNINEQLVQVQHLMDVVMRITHGAKERTKTEWEKLFLDAGFSEYKITANLGFRSLIEIYP
>rna-XM_019396080.1
MANIVKTSSWKMASNLNGSTELLQAQTQTWNHIYNFVSSSAAKCAVQLGIPDVLYKHGKPMCLSDLSAALPLNPSKISFLPILMRSLVQSGFLNEHEDNYYSLTPASRLFVKDDPLSTRSYFLIMHDPCLQKPWFELSSWFQNDFPTAFHTANNGKSLWDYFADEPRGNDIFNDSMANDSRLIANVLITECKHVFEGLTSLVDVGGGTGTVAIAIAKAFPAINCTVLDLPHVIGDLKGSGNLEFVGGSMFEKIPNANAIILKWILHNWGDEDCVKILKKCKESIPSREKGGKVIIIDIVLENPKQKDDSVRAQHNMDMLMMVLFAAKERTKKEWVKLFTEAGFSGYEVTPTLGTRSLIEIYP
>rna-XM_019395896.1
MSRNENGSTDLLRAQAQIWNHMFSFINSSATKCAVQLGIPDVLYKHGKPMSFSDLSAELPLVHPSKVPFLTILMRFLVHSGFLNQHDQNHYSLTPVSRLLATNNLSGTRSHFLINHIQLLQNASFELTSWFQNDSPTAFHTAHGISFWDYFVEKPKLGESFNVAMASDSMLVANVLITECKYVFEGLSSLVDVGGGTGTVAIAIAKAFPMINCTVFDLPHVIGDLKGSGNLEFVGGSMFDKIPNANAILLKWILHDWSDEDCVKILKKCKEAIPCREKGGKVIIIDMVMEDPMLISDEEFVRAQHNMDLLMMVLCAAKERTKKEWEKLFTESGFTQYKITHSLGSRSLIEIYP
>rna-XM_019403901.1
MFIDIGDKAGEVLAAQAHIWNHTFNYINSMSLKCAIQLGIPDIIHSHGRAMTLSELVNALPINKAKGQDYVYRLMRILTHAGFFIQAKVNNENEECYLLSSSSYLLLKDEPMNMIPFLQAQLDPILMDPFHSLSQWFKNGDSTPFATFNGKPLFECAEKERRLNRLFNEAMSSDARLIISIMIEHCKGVFEGLKSIVDVGGGTGTVAKAIADKFPKINCIVFDLPHVIEGYEGSENLSYVRGDMFKSIPSADAILLKHWILHDWSDEECIQILKKCKEAIPSKENGGKFIIDMVLDNQKGDQKTYETQLFWDMLMMGHTSGKERTQQDWAKLFSNAGFSDYKIIPNLGLRSIIEVYP
>rna-XM_019410491.1
MALSNNIGDETREILSAQAHIANHVFNYINSMSLKCAIQLEIPDIIHNHGKPMTLSNLVNALPINKAKGQDCIYRLMRILIHSGFFMQTKINETEEEEEEGYLLTPNSRLLLKNEPLSLVPFVLAQLDPILMDPFQSLSKWLQNDDSTPFATAHGKPLFEYAGDEPKLNYLFNEAMASDARLMISVVIKNGSGIFDGLKSLVDVGGGIGTVAKAISNAFPEVKCTVFDLPHVVEGLDGSNNLSYVGGDMFKSVPSADAILLKWILHDWSDEDCVKILKKCKEAIQSKEKGGKVIIIDIVVDSQNGDNKSFETQLFSDILMMVHVSGKERNPEEWAKLFSDAGFSDYKINPILGLRSVIEVYP
>rna-XM_019377267.1
MAKETNREARTREENQDSQAQADIWKYVFGFTEMAVVKCAIELGIADFLESSQQPVSLNQLSVALGCCSSSLYRVLRFLINRGIFKETSTGNGEISYVQTPLSRLLRKEGGNSMAAFVLFESSPVMLAPWHNLSARVLSKENTVPAFDAAHGKDVWKFAETDPGYNNLLNKAMACDARVSVSAIINGCPEIFKGISSLVDVGGGDGTALRILVEAFPWIKGINFDLPHVASVAPHSNSVQHVGGDMFDYVPKADAAFLMWVLHDWGDDECIQILRKCGEAIPKDTGKVIIVEAVIGKGDERKEDDKLKDVGLMLDMVMMAHTSNGKERTAKEWAYVLSAAGFSRHTINHIDAVQSVIQAYL
>rna-XM_019377276.1
MSINIGDKAREVLAAQAHIWNHTFSYINSMSLKCAIQLGIPDIIHSHGRAMTLSELVNALPIFEYAEKESGFNCLFNEAMASDAPLIISIMIEHCKEVFEGLKSIVDVGGGTGTTAKAIADAFPKVNCIVLDLPHAGS
>rna-XM_019381194.1
MSMNENRSIDLLLAQTQTWNHMFNFISSSAAKCAIELGIPDVLYKHDKPMSLSDLTAELSLIDHSKVSFLPILMRFLVHSGFLNQHEKEHYSLTAASDLLVKDNPLSMRSYFLIIHDPVLLKAWSCLSDWFQDDSSTAFHTAHEKSLWDYYVQEPRVGDSFNESMASDSRLIANVLITECKHVFEGLTSLVDVGGGTGTVAITIAKAFPAIKCTVLDLPRVVGNLKGSGNVEFVGGSMFEKIPNANAILLKWILHNWSDEDCVKILKKCKESIPSREEGGKVIIIDIVLENPNVTNEFVRAQHYMDLLMMVCYAAKQRTKMEWERLFIDAGFNEYKITPTLGTRSLIEIYP
>rna-XM_019383261.1
MDCGRTALPEILQSSDPVQTAQSRLRPHSSPPRPAQSRLRTALAPSAVAHDFSWTALAANELFKAQVHIYKHAFAYFNSMALNCAIQLGIPDIVHNHKKPITLPELVSALKLPSSKSIGIHRLMRLLVHSGFFATAKVDEISETEGYILTTPSRLLLKSEFPNLSPCVRIMIDPVVVTPWQLMLEWFHNKNEEATAFETAHGVPMWEFCAQNPRFDKDFNEGMASDSQMMRLVVKDCKEVFEGMNSLVDVGGGIGIIAKIILEAFPHLKCTVLDLPHVVANMPQSENLSYVGGDMFQSIPPADAIFLQNILHSSSDEDCVKVLKKYREAIAEDVEEGRKGKKVPIIDIVLDTNEDEPDMTQVKLMKDMLMVMFFTGELRGMGSCDSTWKPHVRVRRSDGGAADAAKKKLGKIRRCEDFPVPTRVVDA
>rna-XM_019384391.1
MVVPIVGEHETEILHAQTHIWNHIFSFINSMSLKSAIQLNIPDIIHKHGKPMTLDQLANALSINKAKTTHLRRLMRILIHSGFFVKSRIQENDGESEGIDEGYALAPPSRLLLKDEPLSVTPFLLAMLDPILVKPWHHVSEWFENDHPTPFDTAHGRTFWDYAGHEPRLNHFFNDAMASDAKLVMNVVIKYSKDVFEGLNSIVDVGGGTGTVAKSIANAFPDLQCTVFDLPHVVEGLEGNKNLNYVGGDFFVSIPPADALLLKWILHDWSDEESVKILKKCKEAIPSREKGGKVIIIDMMVDNKIGDDESIETQIFFDMLMMVLVTGRERSEKGWAKLFSDAGFSDYKVTPILGLRSLIEVYP
MGEETNGVARIHEVDKAESQAQEDIWKYMFGFSEMAAVKCAIELGIPDLLENNQEAITLNQLSSALGCSCSNFLYRILRFLINRGIFKEESTGHGEIGYVQTPLSRLLRKDGENSMAALVLLEASPVMLAPWHFLSARALAKGNTAAFSAVHGKDVWEYAETNPEHSKLINDGLACHARVAIRAIIDSCPEIFKGIETLVDVGGGDGTTISLLVKTFPWISGINFDLPHVVSVAPHCHGVQHVAGNMFDSIPKADAAFLMSVLHDWSEDECIQILKNCIKIIPKDTGKVIMVEVVLEKEKGEGNEKLKDVGFMLDMVMMAHTTNGKERTAKEWAQILTAAGFSSHSIKHINAIESVILAYP
>rna-XM_019393499.1
MAKKENNRADHEQLLQAEAQTWDCILSFVRPYCITCAVELGIPDILHKNGIMTISDLVASLPNLNPSKISFLPILMRILVHSGLLHYQKEVDGYSVTSAGSLLVENEPFSKRSNFLFSQNPIALKPFFSLSHWLQDDLPTAFDTTYGKSMWDYCAEEPKFGHIFNDAMASDSKLISHLLINSEQCKHVFEGLTSLVDVGGGTGTVAMAIANAFPRLNCIVLDLPHVIGDRKGITTGNLEFVAGSMFDSIPYANAILLKFILHNWSDEDCVKLLRKCRESIPSKEKGGKVIVIDIVMEDYSSNNINEQLVQVQHLMDVVMRITHGAKERTKTEWEKLFLDAGFSEYKITANLGFRSLIEIYP
>rna-XM_019396080.1
MANIVKTSSWKMASNLNGSTELLQAQTQTWNHIYNFVSSSAAKCAVQLGIPDVLYKHGKPMCLSDLSAALPLNPSKISFLPILMRSLVQSGFLNEHEDNYYSLTPASRLFVKDDPLSTRSYFLIMHDPCLQKPWFELSSWFQNDFPTAFHTANNGKSLWDYFADEPRGNDIFNDSMANDSRLIANVLITECKHVFEGLTSLVDVGGGTGTVAIAIAKAFPAINCTVLDLPHVIGDLKGSGNLEFVGGSMFEKIPNANAIILKWILHNWGDEDCVKILKKCKESIPSREKGGKVIIIDIVLENPKQKDDSVRAQHNMDMLMMVLFAAKERTKKEWVKLFTEAGFSGYEVTPTLGTRSLIEIYP
>rna-XM_019395896.1
MSRNENGSTDLLRAQAQIWNHMFSFINSSATKCAVQLGIPDVLYKHGKPMSFSDLSAELPLVHPSKVPFLTILMRFLVHSGFLNQHDQNHYSLTPVSRLLATNNLSGTRSHFLINHIQLLQNASFELTSWFQNDSPTAFHTAHGISFWDYFVEKPKLGESFNVAMASDSMLVANVLITECKYVFEGLSSLVDVGGGTGTVAIAIAKAFPMINCTVFDLPHVIGDLKGSGNLEFVGGSMFDKIPNANAILLKWILHDWSDEDCVKILKKCKEAIPCREKGGKVIIIDMVMEDPMLISDEEFVRAQHNMDLLMMVLCAAKERTKKEWEKLFTESGFTQYKITHSLGSRSLIEIYP
>rna-XM_019403901.1
MFIDIGDKAGEVLAAQAHIWNHTFNYINSMSLKCAIQLGIPDIIHSHGRAMTLSELVNALPINKAKGQDYVYRLMRILTHAGFFIQAKVNNENEECYLLSSSSYLLLKDEPMNMIPFLQAQLDPILMDPFHSLSQWFKNGDSTPFATFNGKPLFECAEKERRLNRLFNEAMSSDARLIISIMIEHCKGVFEGLKSIVDVGGGTGTVAKAIADKFPKINCIVFDLPHVIEGYEGSENLSYVRGDMFKSIPSADAILLKHWILHDWSDEECIQILKKCKEAIPSKENGGKFIIDMVLDNQKGDQKTYETQLFWDMLMMGHTSGKERTQQDWAKLFSNAGFSDYKIIPNLGLRSIIEVYP
>rna-XM_019410491.1
MALSNNIGDETREILSAQAHIANHVFNYINSMSLKCAIQLEIPDIIHNHGKPMTLSNLVNALPINKAKGQDCIYRLMRILIHSGFFMQTKINETEEEEEEGYLLTPNSRLLLKNEPLSLVPFVLAQLDPILMDPFQSLSKWLQNDDSTPFATAHGKPLFEYAGDEPKLNYLFNEAMASDARLMISVVIKNGSGIFDGLKSLVDVGGGIGTVAKAISNAFPEVKCTVFDLPHVVEGLDGSNNLSYVGGDMFKSVPSADAILLKWILHDWSDEDCVKILKKCKEAIQSKEKGGKVIIIDIVVDSQNGDNKSFETQLFSDILMMVHVSGKERNPEEWAKLFSDAGFSDYKINPILGLRSVIEVYP
>rna-XM_019377267.1
MAKETNREARTREENQDSQAQADIWKYVFGFTEMAVVKCAIELGIADFLESSQQPVSLNQLSVALGCCSSSLYRVLRFLINRGIFKETSTGNGEISYVQTPLSRLLRKEGGNSMAAFVLFESSPVMLAPWHNLSARVLSKENTVPAFDAAHGKDVWKFAETDPGYNNLLNKAMACDARVSVSAIINGCPEIFKGISSLVDVGGGDGTALRILVEAFPWIKGINFDLPHVASVAPHSNSVQHVGGDMFDYVPKADAAFLMWVLHDWGDDECIQILRKCGEAIPKDTGKVIIVEAVIGKGDERKEDDKLKDVGLMLDMVMMAHTSNGKERTAKEWAYVLSAAGFSRHTINHIDAVQSVIQAYL
>rna-XM_019377276.1
MSINIGDKAREVLAAQAHIWNHTFSYINSMSLKCAIQLGIPDIIHSHGRAMTLSELVNALPIFEYAEKESGFNCLFNEAMASDAPLIISIMIEHCKEVFEGLKSIVDVGGGTGTTAKAIADAFPKVNCIVLDLPHAGS
>rna-XM_019381194.1
MSMNENRSIDLLLAQTQTWNHMFNFISSSAAKCAIELGIPDVLYKHDKPMSLSDLTAELSLIDHSKVSFLPILMRFLVHSGFLNQHEKEHYSLTAASDLLVKDNPLSMRSYFLIIHDPVLLKAWSCLSDWFQDDSSTAFHTAHEKSLWDYYVQEPRVGDSFNESMASDSRLIANVLITECKHVFEGLTSLVDVGGGTGTVAITIAKAFPAIKCTVLDLPRVVGNLKGSGNVEFVGGSMFEKIPNANAILLKWILHNWSDEDCVKILKKCKESIPSREEGGKVIIIDIVLENPNVTNEFVRAQHYMDLLMMVCYAAKQRTKMEWERLFIDAGFNEYKITPTLGTRSLIEIYP
>rna-XM_019383261.1
MDCGRTALPEILQSSDPVQTAQSRLRPHSSPPRPAQSRLRTALAPSAVAHDFSWTALAANELFKAQVHIYKHAFAYFNSMALNCAIQLGIPDIVHNHKKPITLPELVSALKLPSSKSIGIHRLMRLLVHSGFFATAKVDEISETEGYILTTPSRLLLKSEFPNLSPCVRIMIDPVVVTPWQLMLEWFHNKNEEATAFETAHGVPMWEFCAQNPRFDKDFNEGMASDSQMMRLVVKDCKEVFEGMNSLVDVGGGIGIIAKIILEAFPHLKCTVLDLPHVVANMPQSENLSYVGGDMFQSIPPADAIFLQNILHSSSDEDCVKVLKKYREAIAEDVEEGRKGKKVPIIDIVLDTNEDEPDMTQVKLMKDMLMVMFFTGELRGMGSCDSTWKPHVRVRRSDGGAADAAKKKLGKIRRCEDFPVPTRVVDA
>rna-XM_019384391.1
MVVPIVGEHETEILHAQTHIWNHIFSFINSMSLKSAIQLNIPDIIHKHGKPMTLDQLANALSINKAKTTHLRRLMRILIHSGFFVKSRIQENDGESEGIDEGYALAPPSRLLLKDEPLSVTPFLLAMLDPILVKPWHHVSEWFENDHPTPFDTAHGRTFWDYAGHEPRLNHFFNDAMASDAKLVMNVVIKYSKDVFEGLNSIVDVGGGTGTVAKSIANAFPDLQCTVFDLPHVVEGLEGNKNLNYVGGDFFVSIPPADALLLKWILHDWSDEESVKILKKCKEAIPSREKGGKVIIIDMMVDNKIGDDESIETQIFFDMLMMVLVTGRERSEKGWAKLFSDAGFSDYKVTPILGLRSLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University