Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Nelumbo nucifera
Species name
Sacred lotus (Nelumbo nucifera) is a species of flowering plant in the family Nelumbonaceae (lotus family).
Species info
Gene sequence info
Nelumbo_nucifera.OMT.fa
Download
>rna-XM_019198102.1
MKPHPDVLHIHGKPMLLSELALALSVPQSRTTWYVLTPSSRLLLKDNPLNVSQLLLAVLDLVLVTPWHFLSGWFQGNGLATPFEATNGRAFWNYGEQDLSNNKMEHELTETQLLFEMLMMGLVTGRERSKQELGKLLVEAGFTHYKIIPILGLRSLIEVFPY
>rna-XM_010262065.2
MAMAIVIDNEEAKMLVQAQAHIWNHIFNFLNSMSLKCAVQLGIPDVLHSHGKPMLLSELVLALGVPQSRTACLHRLMRMLVHSGFFSMHRVYKDPEEEEEEEKGYVLTPSSRLLLKDNPLNVSQFLIAMLDPVLVTPWHFLSAWFQGNGLATPFEATNGRAFWNYGAHDPEYNNLFNVAMANDARLVMSVVLRECEATFQGLGSLVDVGGGTGAAAMAIADKFPQLKCIVFDLPHVVGNLVGSKNLDYVGGDMFDFIPHADAVLLKWILHDWSDEECVKILKRCREAIPCTDKGGRVIIIDMVIGDNKMENELTETQLLFDMLMMGLVTGRERSKQELEKLLLEAGFTHYKIIPILGLRSLIEVYP
>rna-XM_010273389.2
MENQKEVQAAEAKIWNFVYGFADTLVLRCAIELGIADIIHKQGEPLTLSELGAQIPLKSVNTDHLHRLMRYLVHMKLFTKETLDGEARYGLAPPAKLLVKWWEDKGLASIIFGITDKDFIAPWHHLKDSLAGDGEETTFEKVLGKSISTYMADHLEKSMLFNESMVHDTRLFTSVLIQDFKDVFQGIKSLVDVGGGSGTDMGAIAKAFPHLKCTIYGLPHVIADSPDYPEVDRISGDMFKHIPSADAILLKCILHYWGDGQCIEILKRCKESVPREGGIVIIADAVVDLESKHPYLTKTLLSTDLDMMLNTGGKERTEAEWKKLFNAAGFPAYKITHVADVEYSVIEAYPY
>rna-XM_010274082.1
MGQGDEMELEAQAQIWKYIFSFVDSFTLRSAVELGIPDIIHSQGRPITLSQLSACLPIDYANPDRLNRLMRYLVSIGIFSREHGSADDEDDQEDKFGLTCLSKLLVRKLENNMVPFSMLDFKVLMEPWYHLTWSLDGRASGVTAFERVYGTKFWDYAGQDLEFGEKLNEAMACDTSSTMPTLLQQFNQVFADMSSVVDVGGGTGTAAMAIAKSFPNVKCTVFDHPHVVVDDQSDSGGVAKVSGDMFNFIPRADNLLLKWILHNYGDEDCLVILKRCKEALPERGGGKVVIVETVMEGDHNDETAAEIHDDEFTPCRLIMDMEMMLLFGGKERTAKEWQSLVERAGFRRCTMERINSSMHSLIQAYP
>rna-XM_010276073.1
MEYKQELQNPLMDQAMEKAKEEKMEELRAQVRIRNYMNGYADSMALKCAVENGIADIIQKHAKPIALSELAKALPLPTVSTEHLERLMKYWVQLGLFTHEKDGSHGLTRCSKYLLREENTTMAAIILGLVTEWTIGPWHCLARSLEGGPTAFRRYHGRDMWDYVAGHPEASRLFNESMAGDTRLLLPVLMQECGSWLFEGISSLVDVGGGNGTAMVEIAKKFPGIKCTVFDLPHVIRNTNSSESTGVEWVEGDMFESIPPADAVLLREAIPKERGKVIIIDIVMDIEQDPELIRAKLMTDIDMMSDDLTVMDQRHHEAQALSRLAVKAPNPLLRRWHYDRNHQRLHEQSQPPQLALSDYLDCDNVCS
>rna-XM_010277761.2
MEEDMKAQAQVWKHIYGFVESFTLKCAIELGIADILYEHGQPMTLSELASSIPLPSVSQDGLYRVLRYLVHMKLFDLQVDSDGLKKYRLTPASKLLVKNQEKNLASFVLLQLYEIDTWNHLSAAVEGTVTPWEKCHGGVDYIEYFKKDSVANQLLSDAMTSHTSMVTDALVKGCKKAHILDGVGSLIDVGGCTGVAARAIAKWFPSIKCAVFDLPHVVANAPECPEVTRIGGDMFVSIPKTDVVFMKSVLHDWGDEDCVKILKKCKEAISEKGGKAVIVDIVMDVESSPNEFTGARLGMEMDMLVAVGGKERSEKEWHKLFKEAGYSGYKITPIVAIESIIEVFP
>rna-XM_019200018.1
MEDMKAQAQVWKHIYGFAESLALKCAIELGIADILYEHGQPMTLSELASSIPLPSVSQDGLYRVLRYLVHMKLFDLQVDSDGLKKYWLTPASKLLVKSQEKNLASFALLIFYEMDAWHHLSAAVEGTVTPFEKCHEGEDLEELFGKDSVINRLLSEGMTNLTSLMADALVKGCKKAHILDGVGSLIDVGGSTGVAARAIAKSFPSIKCAVLDLPHVVANAPECSEVTWIEGDMFVSIPKTDVVFMKVRSVLHDCGDEDSVKILKICKEAISEKGGKVVIVEIVMDVESSSSPNEITGAKLNLDMSMLVTPGGKERSEEDWQKLFKEAGYSRYKITPIAAFESIIEVFP
>rna-XM_010245228.1
MNSDTSETRSSVAANHWSFAGTERSLLPPLISRTFNPNCNPNIKLGIPEKIHSHGRPISLSELVCAIGIPSTKSDWLRRLMLVLVNSSLISVDRNESGEEELYFLTPSGRLLLKDHPFNIPSFAWFSFPELNRAGQFLSNSFHQSNSVPFQMAHGMSFWDFISKHDELNKGFQDRMISDSRLTISAVVNECSDIFQDLKSLVDVGVGSGTAARLIAETFPHVKCTVYDLPCVIETIPENTRVVVDSIGGDMFEYIPQLMLKVQIPEKIHSHGQPISLSELVSALGIPSTKSDCLRRLMLLLVHMDLVSIQKCENGEKDLYSLTLSGRILLKHHPFNLDPSWSWFSNPALNMAGQCLCGSFHQSNSTPFEMAHQMSLRDFLSKKDELNRQFNDLMASDSRLIMNAVVKECSDIFQGLKSLVDVGGGNGTAARLITEAFPHMKCTVYDLPHVIATIPESTHSIVDSIGGDMFQYIPPSDAIFLKSILHDWSDEDCVRILKRCKEAIPPKEDGGKVIIIDIVLGNEDDKSFELQLFFDITMMVLLGAKERTEGEWKTLFKEAGFSDYKIKRALGFRSIIELYP
>rna-XM_010245752.2
MEIQKEGQAAAAKIWKFVYGFADCLVLRCAIDLGIADIIHKQGEPLTLSELGAQIPVQPVNTDHLHRLMRYLVHMKIFTKETLDGEARYGLAPPAKFIVKGWDKSIVSIILVVTDKDFMAPWHCLKDSLCGEGTAFEKALGRSIWTYMADHPEKNKLFNEGMACDTKLLISALVQDCKDLFQGIMSLVDVGGGTGTAMRAIAKAFPHLKCTIYDLPHVIADSPDYPEVDRIAGDMFKHIPSADAILLKCILHDWDDGECIEILKRCKESVPREGGKVIIVDIVVDLESKHPLTKTRLSLDLDMMVTTGGKERTEAEWKKLLNAAGFPVFKITHISAVQSVIVAYPY
>rna-XM_010249599.2
MEIPKEVQADEVEIWKFGYDFADTLVLRCAIEFGIADIIHKQGEPLTLFELGAQIPVQPVNTDHLHRLMRYMVHMKIFTKETLGGEEXYGLSPHGKFLVKGWDKSMASAILAITDEDFFAPWHCLKDVLAGEGTAFEKALGKSIWAYVADHPEKNKLFNEVMACDTSFITSVLIQDCKDVFQGIKSVVDVGGGTGTAMRDIAKAFPHLKCTIYDLPHVIADSPDYPEVDRIAGDMFKHIPSADAILLKWILHDWDDGECIEILKRCKESVPREGGKVIIVDIVLDPESKDPLTKARLRLDLDMMVYTGGKERSEAEWKKLLNAAGFPGYKILHVAAVQSVIMAYPY
>rna-XM_010249600.2
MEIQKEVQAADVEIRKFGYGFADILVIRCAIQLGIADIIHKQGEPLTLSELEAQIPVKPVNTDHLHRLMRYMVHMKIFTKETPDGEERYGLAPLGKFLVNGWDRNMVSAILAVTDKDFMVPWYRLKDSLVGEGTAFEKALGKTICECMADHPEKKKPFNEAMACDTTRLLTSALIQDCKDLFQGIMSLVDVGGGTGTAMRDIAKTFPHLKCTIYDLPHVIADSPDYPEVDRIAGNMFKHIPSADGILLKCILHDLGDRQCIEILQRCKESVPREGGKVIIVDIVLDPESTDPLTKARLRLDLDMMVYTGGKERSEAEWKKLLNAAGFPRYKILHIAAVQSVIEAYPY
MKPHPDVLHIHGKPMLLSELALALSVPQSRTTWYVLTPSSRLLLKDNPLNVSQLLLAVLDLVLVTPWHFLSGWFQGNGLATPFEATNGRAFWNYGEQDLSNNKMEHELTETQLLFEMLMMGLVTGRERSKQELGKLLVEAGFTHYKIIPILGLRSLIEVFPY
>rna-XM_010262065.2
MAMAIVIDNEEAKMLVQAQAHIWNHIFNFLNSMSLKCAVQLGIPDVLHSHGKPMLLSELVLALGVPQSRTACLHRLMRMLVHSGFFSMHRVYKDPEEEEEEEKGYVLTPSSRLLLKDNPLNVSQFLIAMLDPVLVTPWHFLSAWFQGNGLATPFEATNGRAFWNYGAHDPEYNNLFNVAMANDARLVMSVVLRECEATFQGLGSLVDVGGGTGAAAMAIADKFPQLKCIVFDLPHVVGNLVGSKNLDYVGGDMFDFIPHADAVLLKWILHDWSDEECVKILKRCREAIPCTDKGGRVIIIDMVIGDNKMENELTETQLLFDMLMMGLVTGRERSKQELEKLLLEAGFTHYKIIPILGLRSLIEVYP
>rna-XM_010273389.2
MENQKEVQAAEAKIWNFVYGFADTLVLRCAIELGIADIIHKQGEPLTLSELGAQIPLKSVNTDHLHRLMRYLVHMKLFTKETLDGEARYGLAPPAKLLVKWWEDKGLASIIFGITDKDFIAPWHHLKDSLAGDGEETTFEKVLGKSISTYMADHLEKSMLFNESMVHDTRLFTSVLIQDFKDVFQGIKSLVDVGGGSGTDMGAIAKAFPHLKCTIYGLPHVIADSPDYPEVDRISGDMFKHIPSADAILLKCILHYWGDGQCIEILKRCKESVPREGGIVIIADAVVDLESKHPYLTKTLLSTDLDMMLNTGGKERTEAEWKKLFNAAGFPAYKITHVADVEYSVIEAYPY
>rna-XM_010274082.1
MGQGDEMELEAQAQIWKYIFSFVDSFTLRSAVELGIPDIIHSQGRPITLSQLSACLPIDYANPDRLNRLMRYLVSIGIFSREHGSADDEDDQEDKFGLTCLSKLLVRKLENNMVPFSMLDFKVLMEPWYHLTWSLDGRASGVTAFERVYGTKFWDYAGQDLEFGEKLNEAMACDTSSTMPTLLQQFNQVFADMSSVVDVGGGTGTAAMAIAKSFPNVKCTVFDHPHVVVDDQSDSGGVAKVSGDMFNFIPRADNLLLKWILHNYGDEDCLVILKRCKEALPERGGGKVVIVETVMEGDHNDETAAEIHDDEFTPCRLIMDMEMMLLFGGKERTAKEWQSLVERAGFRRCTMERINSSMHSLIQAYP
>rna-XM_010276073.1
MEYKQELQNPLMDQAMEKAKEEKMEELRAQVRIRNYMNGYADSMALKCAVENGIADIIQKHAKPIALSELAKALPLPTVSTEHLERLMKYWVQLGLFTHEKDGSHGLTRCSKYLLREENTTMAAIILGLVTEWTIGPWHCLARSLEGGPTAFRRYHGRDMWDYVAGHPEASRLFNESMAGDTRLLLPVLMQECGSWLFEGISSLVDVGGGNGTAMVEIAKKFPGIKCTVFDLPHVIRNTNSSESTGVEWVEGDMFESIPPADAVLLREAIPKERGKVIIIDIVMDIEQDPELIRAKLMTDIDMMSDDLTVMDQRHHEAQALSRLAVKAPNPLLRRWHYDRNHQRLHEQSQPPQLALSDYLDCDNVCS
>rna-XM_010277761.2
MEEDMKAQAQVWKHIYGFVESFTLKCAIELGIADILYEHGQPMTLSELASSIPLPSVSQDGLYRVLRYLVHMKLFDLQVDSDGLKKYRLTPASKLLVKNQEKNLASFVLLQLYEIDTWNHLSAAVEGTVTPWEKCHGGVDYIEYFKKDSVANQLLSDAMTSHTSMVTDALVKGCKKAHILDGVGSLIDVGGCTGVAARAIAKWFPSIKCAVFDLPHVVANAPECPEVTRIGGDMFVSIPKTDVVFMKSVLHDWGDEDCVKILKKCKEAISEKGGKAVIVDIVMDVESSPNEFTGARLGMEMDMLVAVGGKERSEKEWHKLFKEAGYSGYKITPIVAIESIIEVFP
>rna-XM_019200018.1
MEDMKAQAQVWKHIYGFAESLALKCAIELGIADILYEHGQPMTLSELASSIPLPSVSQDGLYRVLRYLVHMKLFDLQVDSDGLKKYWLTPASKLLVKSQEKNLASFALLIFYEMDAWHHLSAAVEGTVTPFEKCHEGEDLEELFGKDSVINRLLSEGMTNLTSLMADALVKGCKKAHILDGVGSLIDVGGSTGVAARAIAKSFPSIKCAVLDLPHVVANAPECSEVTWIEGDMFVSIPKTDVVFMKVRSVLHDCGDEDSVKILKICKEAISEKGGKVVIVEIVMDVESSSSPNEITGAKLNLDMSMLVTPGGKERSEEDWQKLFKEAGYSRYKITPIAAFESIIEVFP
>rna-XM_010245228.1
MNSDTSETRSSVAANHWSFAGTERSLLPPLISRTFNPNCNPNIKLGIPEKIHSHGRPISLSELVCAIGIPSTKSDWLRRLMLVLVNSSLISVDRNESGEEELYFLTPSGRLLLKDHPFNIPSFAWFSFPELNRAGQFLSNSFHQSNSVPFQMAHGMSFWDFISKHDELNKGFQDRMISDSRLTISAVVNECSDIFQDLKSLVDVGVGSGTAARLIAETFPHVKCTVYDLPCVIETIPENTRVVVDSIGGDMFEYIPQLMLKVQIPEKIHSHGQPISLSELVSALGIPSTKSDCLRRLMLLLVHMDLVSIQKCENGEKDLYSLTLSGRILLKHHPFNLDPSWSWFSNPALNMAGQCLCGSFHQSNSTPFEMAHQMSLRDFLSKKDELNRQFNDLMASDSRLIMNAVVKECSDIFQGLKSLVDVGGGNGTAARLITEAFPHMKCTVYDLPHVIATIPESTHSIVDSIGGDMFQYIPPSDAIFLKSILHDWSDEDCVRILKRCKEAIPPKEDGGKVIIIDIVLGNEDDKSFELQLFFDITMMVLLGAKERTEGEWKTLFKEAGFSDYKIKRALGFRSIIELYP
>rna-XM_010245752.2
MEIQKEGQAAAAKIWKFVYGFADCLVLRCAIDLGIADIIHKQGEPLTLSELGAQIPVQPVNTDHLHRLMRYLVHMKIFTKETLDGEARYGLAPPAKFIVKGWDKSIVSIILVVTDKDFMAPWHCLKDSLCGEGTAFEKALGRSIWTYMADHPEKNKLFNEGMACDTKLLISALVQDCKDLFQGIMSLVDVGGGTGTAMRAIAKAFPHLKCTIYDLPHVIADSPDYPEVDRIAGDMFKHIPSADAILLKCILHDWDDGECIEILKRCKESVPREGGKVIIVDIVVDLESKHPLTKTRLSLDLDMMVTTGGKERTEAEWKKLLNAAGFPVFKITHISAVQSVIVAYPY
>rna-XM_010249599.2
MEIPKEVQADEVEIWKFGYDFADTLVLRCAIEFGIADIIHKQGEPLTLFELGAQIPVQPVNTDHLHRLMRYMVHMKIFTKETLGGEEXYGLSPHGKFLVKGWDKSMASAILAITDEDFFAPWHCLKDVLAGEGTAFEKALGKSIWAYVADHPEKNKLFNEVMACDTSFITSVLIQDCKDVFQGIKSVVDVGGGTGTAMRDIAKAFPHLKCTIYDLPHVIADSPDYPEVDRIAGDMFKHIPSADAILLKWILHDWDDGECIEILKRCKESVPREGGKVIIVDIVLDPESKDPLTKARLRLDLDMMVYTGGKERSEAEWKKLLNAAGFPGYKILHVAAVQSVIMAYPY
>rna-XM_010249600.2
MEIQKEVQAADVEIRKFGYGFADILVIRCAIQLGIADIIHKQGEPLTLSELEAQIPVKPVNTDHLHRLMRYMVHMKIFTKETPDGEERYGLAPLGKFLVNGWDRNMVSAILAVTDKDFMVPWYRLKDSLVGEGTAFEKALGKTICECMADHPEKKKPFNEAMACDTTRLLTSALIQDCKDLFQGIMSLVDVGGGTGTAMRDIAKTFPHLKCTIYDLPHVIADSPDYPEVDRIAGNMFKHIPSADGILLKCILHDLGDRQCIEILQRCKESVPREGGKVIIVDIVLDPESTDPLTKARLRLDLDMMVYTGGKERSEAEWKKLLNAAGFPRYKILHIAAVQSVIEAYPY
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University