Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Nelumbo nucifera
Species name
Sacred lotus (Nelumbo nucifera) is a species of flowering plant in the family Nelumbonaceae (lotus family).
Species info
Gene sequence info
Nelumbo_nucifera.CHS.fa
Download
>rna-XM_010251015.1
MVSVEEIRNAQRAQGPATVLAIGTATPANCVYQADYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNICAYMAPSLDARQDMVVVEVPKLGKEAASKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPDTSIERPLFQLVSAAQTILPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFTPIGVSDWNSLFWIAHPGGPAILDQVEEKLGLKEEKLRATRNVLSEYGNMSSACVLFILDEMRKKSVEEGRATTGEGLEWGVLFGFGPGLTVETVVLHSLPAVPAH
>rna-XM_010260538.2
MSKTNNNSINGATTNHIDSIISTTTCDCEPRRPGKATVLALGKAFPSQLIPQECLVEGYFRDTKCDDSAIKEKLERLCKNTTVKTRYTVMSKEILDKYPELTTEGSPTIKQRLEIANPAVLEMALEASLACIKEWGRPVGDITHIVYVSSSEIRLPGGDLYLASGLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGYRPPNMARPYDLVGAALFGDGAAALIIGTDPISQIESPFMELNFAVQQFLPGTHNIIDGRLSEEGINFKLGRDLPQKIEDNIESFCRMLMEKANLKEFNDLFWAVHPGGPAILNRLESCLSLKADKLQCSRRALMDYGNVSSNTIFYVMDYMREELKGGGGEEWGLVLAFGPGITFEGILVRSLLQ
>rna-XM_010265840.1
MVLQGICWRDLNHPLGLLMQGSVKEIVGSQVNNAFVSCILPFMQLLQTRKEISLSSIQGLEKSEQFGGSPIIDLLGRLHEAELNPRVKDVWWYAGEKNGIFFNQILISCFGGSFSKRKMGLRAGQWSTYPEYYFRITNSEHKTELKEKFKRMCEKSRIKKSYMHLTEEISKENPNVCAYMAPSLDARQDMVVVEVPKLGEEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCYGGGMVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDNLLGQALFGDGAAAVIVGADPVPGVEKPLFELVSAAQTILPDSHGAIDGHLREVGQKLALKSEKLRATRHILSEYGNMSSACVLFILDEMRKKSIEDGLKTTGEGLEWGVLFGFGPGLTVETVISLRWVYQQGVGLLVKSCNKGRLKKNLDIFNWALREEESKKISQIPQHRLCTADVFVSEDGLFKSVEELWDGEM
>rna-NM_001318155.1
MVTVEDIRKAQRAEGPATVMAIGTANPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNICEYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSELTAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPVPGVEKPLFELVSAAQTILPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSIFWIAHPGGPAILDQVEEKLALKPEKLSATRHILSEYGNMSSACVLFILDEMRKKSIEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSIAA
>rna-XM_010265836.2
MVTVEDIRKAQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLLRATRHILSEYGNMSSACVLFILDEMRKKSIEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSIAA
>rna-XM_010265835.2
MVTVEDIRKAQRAEGPATVMAIGTANPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNICEYMASSLDARQDMVVVEVPKLGKEAXTKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLHSHGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSIFWIAHPGGPAILDQVEEKLALKPEKLSATRHILSEYGNMSSACVLFILDEMRKKSIEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSIAA
>rna-XM_010270393.2
MWSEGDTIQGGLLPKKVSPGKTKLLALGKAFPNQLVIQEYLVDGYFRNTNCDDPDLKQKLARLCKTTTVKTRYVVMSEEILAKYPELAVEGLPTVKQRLDISNKAVTQMAIEASQACIKNWGRPSSDITHLVYVSSSEARLPGGDLYLARGLGLSPEVRRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSANRPYDLVGVALFGDGAGAMILGRDPIPGIERPLFELHTAIQNFLPDTEKTIDGRLTEEGINFKLERDLPNIIENHVQGFCDKLIQAVGSGSSYDDNDYNNMFWAVHPGGPAILNRLEKRLNLLPEKLSASRRALMNFGNASSNTIVYVLEYMVEESLKMKKEGKQDSEWGLILAFGPGITFEGILARNLLV
MVSVEEIRNAQRAQGPATVLAIGTATPANCVYQADYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNICAYMAPSLDARQDMVVVEVPKLGKEAASKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPDTSIERPLFQLVSAAQTILPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFTPIGVSDWNSLFWIAHPGGPAILDQVEEKLGLKEEKLRATRNVLSEYGNMSSACVLFILDEMRKKSVEEGRATTGEGLEWGVLFGFGPGLTVETVVLHSLPAVPAH
>rna-XM_010260538.2
MSKTNNNSINGATTNHIDSIISTTTCDCEPRRPGKATVLALGKAFPSQLIPQECLVEGYFRDTKCDDSAIKEKLERLCKNTTVKTRYTVMSKEILDKYPELTTEGSPTIKQRLEIANPAVLEMALEASLACIKEWGRPVGDITHIVYVSSSEIRLPGGDLYLASGLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGYRPPNMARPYDLVGAALFGDGAAALIIGTDPISQIESPFMELNFAVQQFLPGTHNIIDGRLSEEGINFKLGRDLPQKIEDNIESFCRMLMEKANLKEFNDLFWAVHPGGPAILNRLESCLSLKADKLQCSRRALMDYGNVSSNTIFYVMDYMREELKGGGGEEWGLVLAFGPGITFEGILVRSLLQ
>rna-XM_010265840.1
MVLQGICWRDLNHPLGLLMQGSVKEIVGSQVNNAFVSCILPFMQLLQTRKEISLSSIQGLEKSEQFGGSPIIDLLGRLHEAELNPRVKDVWWYAGEKNGIFFNQILISCFGGSFSKRKMGLRAGQWSTYPEYYFRITNSEHKTELKEKFKRMCEKSRIKKSYMHLTEEISKENPNVCAYMAPSLDARQDMVVVEVPKLGEEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCYGGGMVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDNLLGQALFGDGAAAVIVGADPVPGVEKPLFELVSAAQTILPDSHGAIDGHLREVGQKLALKSEKLRATRHILSEYGNMSSACVLFILDEMRKKSIEDGLKTTGEGLEWGVLFGFGPGLTVETVISLRWVYQQGVGLLVKSCNKGRLKKNLDIFNWALREEESKKISQIPQHRLCTADVFVSEDGLFKSVEELWDGEM
>rna-NM_001318155.1
MVTVEDIRKAQRAEGPATVMAIGTANPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNICEYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSELTAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPVPGVEKPLFELVSAAQTILPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSIFWIAHPGGPAILDQVEEKLALKPEKLSATRHILSEYGNMSSACVLFILDEMRKKSIEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSIAA
>rna-XM_010265836.2
MVTVEDIRKAQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLLRATRHILSEYGNMSSACVLFILDEMRKKSIEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSIAA
>rna-XM_010265835.2
MVTVEDIRKAQRAEGPATVMAIGTANPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNICEYMASSLDARQDMVVVEVPKLGKEAXTKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLHSHGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSIFWIAHPGGPAILDQVEEKLALKPEKLSATRHILSEYGNMSSACVLFILDEMRKKSIEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSIAA
>rna-XM_010270393.2
MWSEGDTIQGGLLPKKVSPGKTKLLALGKAFPNQLVIQEYLVDGYFRNTNCDDPDLKQKLARLCKTTTVKTRYVVMSEEILAKYPELAVEGLPTVKQRLDISNKAVTQMAIEASQACIKNWGRPSSDITHLVYVSSSEARLPGGDLYLARGLGLSPEVRRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSANRPYDLVGVALFGDGAGAMILGRDPIPGIERPLFELHTAIQNFLPDTEKTIDGRLTEEGINFKLERDLPNIIENHVQGFCDKLIQAVGSGSSYDDNDYNNMFWAVHPGGPAILNRLEKRLNLLPEKLSASRRALMNFGNASSNTIVYVLEYMVEESLKMKKEGKQDSEWGLILAFGPGITFEGILARNLLV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University