Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Myagrum perfoliatum
Species name
Myagrum perfoliatum is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Myagrum_perfoliatum.HIDH.fa
Download
>Myper.0001s0959.1.v2.1
MDSEIAFDNSPGYRVYKNGRIERLLGETFTPPSLTPQNGVISKDTVYSPEKNLSVRIHLPEKASVTGEKLPVLVYFHGGGFIIETAFSPAYHTFLTSAAAAADCLAISVDYRRAPEFPIPAAYEDSWDSLKWVLSHASGSGQESWINKHGDFTKVFLAGDSAGANISHHLAIRAKREKLDETISGIILIHPYFWGKTPIDELETRDETRRKRVERSWGVASPNSENGVDDPWFNVVGSESSDISGLGCGRVLVVLAGDDMYVRQGFGYAAKLEKSGWEGEVEVMEIKDEGHVHHLKNPNTDNARKVVNKVAEFINK
>Myper.0002s1664.1.v2.1
MDSDSDIAYDYSPRFRVYKNGRIKRLVTETFVPPSLNPENGVVSKDAVYSPEKNLSLRIYLPHKAVETRENEKKEKLPLLVYFHGGGFIMETAFSPVYHTFLTSTVSAGNCIAVSVDYRRAPEHLIPIAYEDSWDAIKWILTHVSGSGPEYWVNENADFSRVFIAGDSAGANIAHHMGIRAGRERSDTGNFNISGMTLFHPYFLSKAPVDEEQDVGALRYMEGLWKIASPNSEKGTEDPWISVVGSDLSRLGCGRVLVMVAGDDVLAREGRVYAAELEKCGWQGKVEVMETKDEGHVFHIRNPDSDNARLVVQRFAEFLRDDTSRC
>Myper.0004s0788.1.v2.1
MGSLGEEPQIAEDCMGLIQLLSDGTVLRSKSIDLITQQTPLADHKTVLFKDSLFHEPNNLHLRLYKPVCASNRNTTTIPVVIFFHGGGFCFGSRSWPHFHNFCLTLASSLHALVVAPDYRLAPEHRLPAAFEDAGDALMWLRDQAVSGDGDHWFEGGPGVDFDRVYVLGDSSGGNIAHHLAFRFGSGSVELSPVRVRGYVLLGPFFGGEERTNSEEGPSEALLSLDLLDKFWRLSLPEGATRDHPMANPFGPRSPALESISIEPMLVIAGGSELLRDRAKEYAYKLKKMGGKKVEYIEFENEEHGFFSKNPSSDAAEQLLGIIGDFMDNLSNIF
>Myper.0004s1649.1.v2.1
MAAISFTHNHQSSDNRRGGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTVHPSAKVTAFDIKLSNDTSARVYIPDAAAFAPSATLPLLVYFHGGGFCVGSAAWSCYHDFLTDLAVKARCVVVSVNYRLAPEHRLPAAYDDGVNVVSWLMKQGSNGGYSWVSKCNLSNVFLAGDSAGANIAYQVAVRIIAGGKSVNTTNLKGVILIHPFFGGESRTYSEKQQHSKSSALTLSASDTYWRLALPRGASREHPWCNPLVSSSVREARLPTTMVFMAEFDILKDRNLEMCKVMRSHGKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMMCRLRNFIHP
>Myper.0005s1571.1.v2.1
MDSEIAADFSPLLKIYKSGRIERLMGETTVPASLTPQNGVVSKDVVYSPDDNLSVRIYLPEKAAETGAKLPLLVYFHGGGFIIETAFSPTYHTFVTAAVSASDCVAVSVDYRRAPEHPIPISYDDSWTSLKWVFTHIARCGPESWLNKHADFSKVFLAGDSAGANMAHHMAVRAAKEKLSPELNDSGISGTILVHPYFWSKTPVDDKETKDVTLRAKIEGIWKMASPNSKDGVDDPYINVVQSESVDISGLGCGKVLVMVAEKDALARQGWGYAAKLEKSGWKGKVELVESEGEDHVFHLTRPDCDKALEAMKKFAGFLKGDM
>Myper.0005s1569.1.v2.1
MDSEIAVDYSPFLTIYKSGRIGRLMGETTVPPSLTPQNGIITKDVVYSPDDSLSVRIYLPEKAAETGGKLPLLVYFHGGGFIIETAFSPSYHTFVTAAVSASDCVAVSVDYRRAPEHPIPIPYDDSWTSLKWVFTHMAGCGPESWLNKHADFSKVFLAGDSAGANIAHHMAVRAAKEKLSAELNDSGLSGIILVHPYFWSKTPVDDKETKDVTLRSKIVGLWTIASPSSKDGVDDPYINVVQSESVDLSGLGCGKVLVMVAEKDTLARQGWGYVAKLEKSGWKGKVELVESEGEDHVFHLMRPDCEKALEAMKIFAGFLQGKM
>Myper.0007s0857.1.v2.1
MLRRIAFSSSICSRPLVFRFFRHFPRSYLSLSSSQNAVCVSGRHHLRRLSTPASTLRCICSHASSDLLSEHPPFVRIYKDGRVERLSGTEVVPASLTPQNGVVSKDVVYSPEHNLSVRLFLPHKVTELAAGNNKLPLLIYIHGGAWIIESPFSPSYHNFLTEVVKTANCLAVSIQYRRAPEDPVPAAYEDSWSAIQWVYSHSDGSGPEEWINEYADFNRVFLAGDSAGANMSHHMAIRAGKEKLKPRIKGIAIVHPAFWGKDPVDEHDLQDREARSRIAEVWEKLVSPNSVHGADDPWFNVVGSGSDFSGLGCERVLVAVAGKDVFVRQGLGYAAKLEKSGWKGDVEVMEEEEEDHCFHLLNPSSQNAPKFMKKFVEFITS
>Myper.0007s1064.1.v2.1
MLPQRNRVLFSTEKSYIGSLPFITLFLLFLPNRYNNKLSLSLMESTKKQVSLEVLPWLVVHSDGTLERLAGTEVCPPGLDPETGVLSKDIIIDPKTGLSARIYRPGSIQPGQRLPLVLYFHGGAFLIASASLPNYHTSVNKLVAKANVIAVSVDYRLAPEHPLPTAYEDSWNALQGVQAGNEPWINDYADFDRLFLVGDSAGANISHHLAFRTKQSDQTVKIKGIGMIHPYFWGTQPIGSEVTDEARKQMVDGWWRFVCPSEKGSDDPLINPFADGSLDLEGLWCERVMITVAEKDILSERGKMYYERLVKSKWRGEAEIMETKGKDHVFHIFEPDCDEAREMVRRLALFINQVES
>Myper.0007s0856.1.v2.1
MESEIASEFLPFGRIYKDGRVERLTGTEIIPASLDAANDVVSKDVVYSPEHNLSVRLFLPHKLAAGNNKLPLLIYIHGGAWIIESPFSPLYHNYLTEVVKSANCLGVSIQYRRAPEHPVPAAYEDSWSAIQWIFSHSDGSGPEEWINKHADFGRVFIGGDSAGANMSHHMAMRAGKEKLCPRIKGIAIVHPAFWGTDPVDEHDVQDRETRSGIAELWEKISSPNSVNGTDDPLFNVVGSDSDLSGLGCEKVLVAVAGKDVFVRQGLGYAAKLEKSGWEGDVEVVEEEEEGHVFHLQNPNSENALRLLKTFVKFITG
>Myper.0007s0858.1.v2.1
MVGSLFTSNHLPFIRIHKNGHVERLRGNDVVPASLDTQNDVVSKDVVYSPEHNLSVRLFLPHKSTQLAAGKKLPLLIYFHGGAYIMQSPFSPVYNNYVAEVVKTSNCLAVSVQYRRAPEHPIPAAYDDSWSAIQWIFSHSGGVGEEVWINEYADFGKVFVAGDSAGANISHHMAIRAGKEKLDPRIKGVVMVHPGFWGKDPVDEKDVQDEGTRRGVAEIWEKFVSPNSVDGVNDPWLNVVGSGLDISGLGCERVLVAVAGKDVFGRQGLAYAAKLEKSGWKGELEVVEEEEEDHCFHLRNPNSENALRLMKTFVAFIITSSAE
>Myper.0016s0678.1.v2.1
MGATSLTHVTTIDPNNTNIHGPVLDEVEGRLRVYKDGHVERSPLVPFVGPSLPLDLGVACSDVHIDKLTNVWARLYVPMVTASSVSKLPLLVYFHGGGFCIGSASWSCYHQFLARLSANSQCLVMSVNYRLAPENPLPAAYEDGVNAILWLKKTRNDNLWSKLCDFGKIFLAGDSAGGNIAHHVAARLEATDGLIKPLKIEGTILIQPFFAGEARTESERRAENNMKRSVLTLASSDAWWRLALPRDANREHPYCKPVTFTTRTLVCVAEMDVLMDRAMEMCDSNEKMIKRVLYKGVGHAFQILDKSQLAHTMTLEMLCHIDAFIHHNDPIN
MDSEIAFDNSPGYRVYKNGRIERLLGETFTPPSLTPQNGVISKDTVYSPEKNLSVRIHLPEKASVTGEKLPVLVYFHGGGFIIETAFSPAYHTFLTSAAAAADCLAISVDYRRAPEFPIPAAYEDSWDSLKWVLSHASGSGQESWINKHGDFTKVFLAGDSAGANISHHLAIRAKREKLDETISGIILIHPYFWGKTPIDELETRDETRRKRVERSWGVASPNSENGVDDPWFNVVGSESSDISGLGCGRVLVVLAGDDMYVRQGFGYAAKLEKSGWEGEVEVMEIKDEGHVHHLKNPNTDNARKVVNKVAEFINK
>Myper.0002s1664.1.v2.1
MDSDSDIAYDYSPRFRVYKNGRIKRLVTETFVPPSLNPENGVVSKDAVYSPEKNLSLRIYLPHKAVETRENEKKEKLPLLVYFHGGGFIMETAFSPVYHTFLTSTVSAGNCIAVSVDYRRAPEHLIPIAYEDSWDAIKWILTHVSGSGPEYWVNENADFSRVFIAGDSAGANIAHHMGIRAGRERSDTGNFNISGMTLFHPYFLSKAPVDEEQDVGALRYMEGLWKIASPNSEKGTEDPWISVVGSDLSRLGCGRVLVMVAGDDVLAREGRVYAAELEKCGWQGKVEVMETKDEGHVFHIRNPDSDNARLVVQRFAEFLRDDTSRC
>Myper.0004s0788.1.v2.1
MGSLGEEPQIAEDCMGLIQLLSDGTVLRSKSIDLITQQTPLADHKTVLFKDSLFHEPNNLHLRLYKPVCASNRNTTTIPVVIFFHGGGFCFGSRSWPHFHNFCLTLASSLHALVVAPDYRLAPEHRLPAAFEDAGDALMWLRDQAVSGDGDHWFEGGPGVDFDRVYVLGDSSGGNIAHHLAFRFGSGSVELSPVRVRGYVLLGPFFGGEERTNSEEGPSEALLSLDLLDKFWRLSLPEGATRDHPMANPFGPRSPALESISIEPMLVIAGGSELLRDRAKEYAYKLKKMGGKKVEYIEFENEEHGFFSKNPSSDAAEQLLGIIGDFMDNLSNIF
>Myper.0004s1649.1.v2.1
MAAISFTHNHQSSDNRRGGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTVHPSAKVTAFDIKLSNDTSARVYIPDAAAFAPSATLPLLVYFHGGGFCVGSAAWSCYHDFLTDLAVKARCVVVSVNYRLAPEHRLPAAYDDGVNVVSWLMKQGSNGGYSWVSKCNLSNVFLAGDSAGANIAYQVAVRIIAGGKSVNTTNLKGVILIHPFFGGESRTYSEKQQHSKSSALTLSASDTYWRLALPRGASREHPWCNPLVSSSVREARLPTTMVFMAEFDILKDRNLEMCKVMRSHGKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMMCRLRNFIHP
>Myper.0005s1571.1.v2.1
MDSEIAADFSPLLKIYKSGRIERLMGETTVPASLTPQNGVVSKDVVYSPDDNLSVRIYLPEKAAETGAKLPLLVYFHGGGFIIETAFSPTYHTFVTAAVSASDCVAVSVDYRRAPEHPIPISYDDSWTSLKWVFTHIARCGPESWLNKHADFSKVFLAGDSAGANMAHHMAVRAAKEKLSPELNDSGISGTILVHPYFWSKTPVDDKETKDVTLRAKIEGIWKMASPNSKDGVDDPYINVVQSESVDISGLGCGKVLVMVAEKDALARQGWGYAAKLEKSGWKGKVELVESEGEDHVFHLTRPDCDKALEAMKKFAGFLKGDM
>Myper.0005s1569.1.v2.1
MDSEIAVDYSPFLTIYKSGRIGRLMGETTVPPSLTPQNGIITKDVVYSPDDSLSVRIYLPEKAAETGGKLPLLVYFHGGGFIIETAFSPSYHTFVTAAVSASDCVAVSVDYRRAPEHPIPIPYDDSWTSLKWVFTHMAGCGPESWLNKHADFSKVFLAGDSAGANIAHHMAVRAAKEKLSAELNDSGLSGIILVHPYFWSKTPVDDKETKDVTLRSKIVGLWTIASPSSKDGVDDPYINVVQSESVDLSGLGCGKVLVMVAEKDTLARQGWGYVAKLEKSGWKGKVELVESEGEDHVFHLMRPDCEKALEAMKIFAGFLQGKM
>Myper.0007s0857.1.v2.1
MLRRIAFSSSICSRPLVFRFFRHFPRSYLSLSSSQNAVCVSGRHHLRRLSTPASTLRCICSHASSDLLSEHPPFVRIYKDGRVERLSGTEVVPASLTPQNGVVSKDVVYSPEHNLSVRLFLPHKVTELAAGNNKLPLLIYIHGGAWIIESPFSPSYHNFLTEVVKTANCLAVSIQYRRAPEDPVPAAYEDSWSAIQWVYSHSDGSGPEEWINEYADFNRVFLAGDSAGANMSHHMAIRAGKEKLKPRIKGIAIVHPAFWGKDPVDEHDLQDREARSRIAEVWEKLVSPNSVHGADDPWFNVVGSGSDFSGLGCERVLVAVAGKDVFVRQGLGYAAKLEKSGWKGDVEVMEEEEEDHCFHLLNPSSQNAPKFMKKFVEFITS
>Myper.0007s1064.1.v2.1
MLPQRNRVLFSTEKSYIGSLPFITLFLLFLPNRYNNKLSLSLMESTKKQVSLEVLPWLVVHSDGTLERLAGTEVCPPGLDPETGVLSKDIIIDPKTGLSARIYRPGSIQPGQRLPLVLYFHGGAFLIASASLPNYHTSVNKLVAKANVIAVSVDYRLAPEHPLPTAYEDSWNALQGVQAGNEPWINDYADFDRLFLVGDSAGANISHHLAFRTKQSDQTVKIKGIGMIHPYFWGTQPIGSEVTDEARKQMVDGWWRFVCPSEKGSDDPLINPFADGSLDLEGLWCERVMITVAEKDILSERGKMYYERLVKSKWRGEAEIMETKGKDHVFHIFEPDCDEAREMVRRLALFINQVES
>Myper.0007s0856.1.v2.1
MESEIASEFLPFGRIYKDGRVERLTGTEIIPASLDAANDVVSKDVVYSPEHNLSVRLFLPHKLAAGNNKLPLLIYIHGGAWIIESPFSPLYHNYLTEVVKSANCLGVSIQYRRAPEHPVPAAYEDSWSAIQWIFSHSDGSGPEEWINKHADFGRVFIGGDSAGANMSHHMAMRAGKEKLCPRIKGIAIVHPAFWGTDPVDEHDVQDRETRSGIAELWEKISSPNSVNGTDDPLFNVVGSDSDLSGLGCEKVLVAVAGKDVFVRQGLGYAAKLEKSGWEGDVEVVEEEEEGHVFHLQNPNSENALRLLKTFVKFITG
>Myper.0007s0858.1.v2.1
MVGSLFTSNHLPFIRIHKNGHVERLRGNDVVPASLDTQNDVVSKDVVYSPEHNLSVRLFLPHKSTQLAAGKKLPLLIYFHGGAYIMQSPFSPVYNNYVAEVVKTSNCLAVSVQYRRAPEHPIPAAYDDSWSAIQWIFSHSGGVGEEVWINEYADFGKVFVAGDSAGANISHHMAIRAGKEKLDPRIKGVVMVHPGFWGKDPVDEKDVQDEGTRRGVAEIWEKFVSPNSVDGVNDPWLNVVGSGLDISGLGCERVLVAVAGKDVFGRQGLAYAAKLEKSGWKGELEVVEEEEEDHCFHLRNPNSENALRLMKTFVAFIITSSAE
>Myper.0016s0678.1.v2.1
MGATSLTHVTTIDPNNTNIHGPVLDEVEGRLRVYKDGHVERSPLVPFVGPSLPLDLGVACSDVHIDKLTNVWARLYVPMVTASSVSKLPLLVYFHGGGFCIGSASWSCYHQFLARLSANSQCLVMSVNYRLAPENPLPAAYEDGVNAILWLKKTRNDNLWSKLCDFGKIFLAGDSAGGNIAHHVAARLEATDGLIKPLKIEGTILIQPFFAGEARTESERRAENNMKRSVLTLASSDAWWRLALPRDANREHPYCKPVTFTTRTLVCVAEMDVLMDRAMEMCDSNEKMIKRVLYKGVGHAFQILDKSQLAHTMTLEMLCHIDAFIHHNDPIN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University