Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Myagrum perfoliatum
Species name
Myagrum perfoliatum is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Myagrum_perfoliatum.CHS.fa
Download
>Myper.0001s1452.1.v2.1
MVMGASSLDEMRKAQRANGPASILAIGTANPANYVMQAGYPEYYFRITNSEHMTELKAKFKRMCDRSMIRKRYMHLTEEFLKDNPNICAYMAPSLDVRQDILVAEVPKLGKEAAVKAIKEWGQPKSMITHLIFCTTSGVDMPGADYQLINLLGLCLSVKRVMMYHQGCFAGGTVLRLAKDIAENNRGARVLIVCSEITVVTFRGPSDTHLDSLVGQSLFGDGAAALIVGSDPDTSAGEKPIFEMVSAAQTILPDSEGAIEGHLREVGLTFHLLKTVPGLISKNIEKCLDEAFKPLGISDWNSLFWIAHPGGPAILEQVEIKLGLKAEKMRATRHVLSEYGNMPSACVFFKLDEMRRKTAEDGAATTGEGLEWGVVFGFGPGLTVETVVLHSVPL
>Myper.0002s3422.1.v2.1
MITLNLLEPAVKLGAICITSFGSRRFYVPFKSQKEMSNSGMNGIEKQSSSTVTRRVANPGKATVLALGKAFPSQVVPQENLVEGFLRDTKCDDAFIKEKLEHLCKTTTVKTRYTVLSRQILDKYPELTTEGSPTIKQRLEIANEAVVEMALEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSARLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGADPRECEAPFMELHYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEENIEDFCKKLMGKAGDSSMEFNDMFWAVHPGGPAILNRLETKLKLEREKLESSRRALVDYGNVSSNTILYVMENVRDELKKKGDAAQEWGLGLAFGPGITFEGLLIRSLTSP
>Myper.0004s1443.1.v2.1
MVMGTPSSLDEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPDMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDISVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWVAHPGGPAILDEVEKKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSAEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>Myper.0011s0238.1.v2.1
MLASRTTRRRVANQGKATVLALGKAFPSNVVSQENLVEEYLREIKCDDLSIKDKLQHLCKTTTVKTRYTVMSRETLHKYPELATEGSPTIKQRLEIANEAVVQMAFEASLACIKEWGRAVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGVSGLRVAKDIAENNPGSRVLLTTSETMVLGFRPPNKARPYDLVGAALFGDGAAALIIGADPTESEAPFMELHCALQQFLPGTQGVIDGRLSEEGISFKLGRDLPQKIEDNVEEFCKKLAAKAGSGSGSSEFNDLFWAVHPGGPAILNGLETKLKLKPEKLECSRRALMDYGNVSSNTIFYIMDKVRDELDTKGRDGEEWGLGLAFGPGITFEGFLMRSL
>Myper.0015s0530.1.v2.1
MGSIDATELGSEKKPNPGKATILAFGKAFPHQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILRKYPELAIEGGSTVKQRLDICNDAVTEMAVEASRACIKNWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPDPICEKPLFELHTAIQNFLPDTEKTIDGRLTETGINFTLSRELPQIIEDNVENFCKNLIGKAGLAHKDYNQMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESRKARSMTETENEWGLILAFGPGVTFEGIVARNLDV
MVMGASSLDEMRKAQRANGPASILAIGTANPANYVMQAGYPEYYFRITNSEHMTELKAKFKRMCDRSMIRKRYMHLTEEFLKDNPNICAYMAPSLDVRQDILVAEVPKLGKEAAVKAIKEWGQPKSMITHLIFCTTSGVDMPGADYQLINLLGLCLSVKRVMMYHQGCFAGGTVLRLAKDIAENNRGARVLIVCSEITVVTFRGPSDTHLDSLVGQSLFGDGAAALIVGSDPDTSAGEKPIFEMVSAAQTILPDSEGAIEGHLREVGLTFHLLKTVPGLISKNIEKCLDEAFKPLGISDWNSLFWIAHPGGPAILEQVEIKLGLKAEKMRATRHVLSEYGNMPSACVFFKLDEMRRKTAEDGAATTGEGLEWGVVFGFGPGLTVETVVLHSVPL
>Myper.0002s3422.1.v2.1
MITLNLLEPAVKLGAICITSFGSRRFYVPFKSQKEMSNSGMNGIEKQSSSTVTRRVANPGKATVLALGKAFPSQVVPQENLVEGFLRDTKCDDAFIKEKLEHLCKTTTVKTRYTVLSRQILDKYPELTTEGSPTIKQRLEIANEAVVEMALEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSARLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGADPRECEAPFMELHYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEENIEDFCKKLMGKAGDSSMEFNDMFWAVHPGGPAILNRLETKLKLEREKLESSRRALVDYGNVSSNTILYVMENVRDELKKKGDAAQEWGLGLAFGPGITFEGLLIRSLTSP
>Myper.0004s1443.1.v2.1
MVMGTPSSLDEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPDMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDISVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWVAHPGGPAILDEVEKKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSAEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>Myper.0011s0238.1.v2.1
MLASRTTRRRVANQGKATVLALGKAFPSNVVSQENLVEEYLREIKCDDLSIKDKLQHLCKTTTVKTRYTVMSRETLHKYPELATEGSPTIKQRLEIANEAVVQMAFEASLACIKEWGRAVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGVSGLRVAKDIAENNPGSRVLLTTSETMVLGFRPPNKARPYDLVGAALFGDGAAALIIGADPTESEAPFMELHCALQQFLPGTQGVIDGRLSEEGISFKLGRDLPQKIEDNVEEFCKKLAAKAGSGSGSSEFNDLFWAVHPGGPAILNGLETKLKLKPEKLECSRRALMDYGNVSSNTIFYIMDKVRDELDTKGRDGEEWGLGLAFGPGITFEGFLMRSL
>Myper.0015s0530.1.v2.1
MGSIDATELGSEKKPNPGKATILAFGKAFPHQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILRKYPELAIEGGSTVKQRLDICNDAVTEMAVEASRACIKNWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPDPICEKPLFELHTAIQNFLPDTEKTIDGRLTETGINFTLSRELPQIIEDNVENFCKNLIGKAGLAHKDYNQMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESRKARSMTETENEWGLILAFGPGVTFEGIVARNLDV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University