Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Moringa oleifera
Species name
Horseradish tree (Moringa oleifera) is a species of eudicot in the family Moringaceae (horseradish tree family).
Species info
Gene sequence info
Moringa_oleifera.COMT.fa
Download
>Morol36190S12119_MOROL
MQLASSSVLPMVLKTAMELGVLEIIRRAGPGALLSPSEIAYSILTCSLTTNEQDIQVLRIYCLAPVAKYFPQSQDGGSLVPILNLIQDKNTVLERRHQFNRTYGMSGMEYVGKDARLRGMFQGFGRDSNFLFMEEILKTCKGFDDVKLVVDVGSGDGSVLNVIVVDVGSGDGSVLNVIVSANPTVKGINYDLPAVVGKSPPYPGMLTGCPFRKKRN
>Morol36224S13220_MOROL
MAGSIRGSQNEVTGRTHPNSSCILQIQELCRALSLTTPAQGTKMSDLQRINDHDRVDEDQELGKQAIRLANAVVLPMVLKSALELGLVDTIYAAGDGAFLSPVEIASRLPSRNPQTPVLLDRVLRLLASYSVLRCRLRNGDNGDVERLYGAGPISRFLVKDQDSGSVGPLFLLHHDKVFMESWYHLNDVILEGGIPFNRAYGMTAFEYPGTDQRFNRVFNQAMSSHTTLIMRKILDVYQGFEGLNLLVDVGGGIGVTLNLITSKYPHIKGVNYDLPHVLADAPSYPGVEHVGGDMFVSVPKGDAIFMKWILHDWSDEHCLKLLKNCWEALPNTGKVIIVESILPMVPESTVSSNIVFEQDLFMLAQNPGGKERTQKEFEGLAVTSGFLGCEVICSAYNSWVMEFHKRADP
>Morol36224S13221_MOROL
MSDLQRINDHDRVDEDQELGKQAIRLANAVVLPMVLKSALELGLVDTIYAAGDGAFLSPVEIASRLPSRNPQAPVLLDRVLRLLASYSVLRCRLRNGDNGDVERLYGTGPISRFLVKNQDSGSVGPLFLLLHDKVFMESWYHLNDVILEGGIPFNRAYGMTAFEYPGTDQRFNRVFNQAMSSHTTLIMRKILDVYQGFEGLNLLVDVGGGIGVTLNLITSKYPHIRGVNYDLPHVLADAPSYPGVEHVGGDMFVSVPKGDAIFMKWILHDWSDEHCLKLLKNCWEALPNTGKVIIVESILPMVPESTVSSNIVFEQDLFMLAQNPGGKERTQKEFEGLAVTSGFLGCEVICTAYNSWVMEFHERADP
>Morol36248S13692_MOROL
MGSTGETQITPTQVSDEEANLFAMQLASASVLPMVLKSAIELDLLEIMAKAGPGAFLSPTYIASQLHTKNPDAPVMLDRMLRLLASYSVLTCSLRSLPDGRAERLYGLGPVCKFLTKNEDGVSLSALCLMNQDKVLMESWYHLKDAVLEGGIPFNRAYGMSAFEYHGTDPRFNKVFNEGMSNHSTITMKKILEIYIGFGGLSSVVDVGGGTGASLSMIVSKYPTIRGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKLLRNCYEALPNNGKVIIAESILPVAPDPSLLTKLVVHVDCIMLAHNPGGKERTEKEFEALAKGAGFQGFQVVCSAFGSYIMEFLKNV
>Morol36447S16461_MOROL
MICPSRRGPLSKVSKGQPPVQSPDYISGVATLEIYRDQPVAAKGNRRKLGSERAMEEESGERRIEARLRIMELANMISVPMSLNAVVRLNVADAIWQGGANIPLSTSEILARILPPSSAATADPENLQRVLRMLTSYGVFEEHLMASDGFQRKYSLTDVGKTLVTDPEGLSYAPYVLQHHQDALMRAWPLVHEAVLDPTSEPFVKANGEPAYVHYGKDPKMNVLMQKAMSGVSVPFMKAILECYDGFDGVEQLVDVGGSAGDCLRIILQKHPTVREGINYDLPEVVAKAPPIPGVKHVGGNMFESIPSGDAIFMKWVLTTWTDSECKKIMENCYKALPVGGKLIACEPVLPLQSDDSHRTRALLEGDIFVMTIYKAKGMHRTEEEFKQLGLSAGFPRFKALYFDNFYTVLEFQK
>Morol36514S04780_MOROL
MKEKQEEALANAMQLVLASVLPIHGNASGHRSWILRLLVSHSVLACSVINQERFYSLTPVSEYFVCNKDGVSLGALMPLTHDKIYLESWSQLKDAVLDGGIPFNRVHGMYSFECPAYDSRFNQTTIVIKRILEIYKGFEQLKQLVDVGGDLGVNLKAITTKYPHIRGINFDLPHVIGHPLSYPDDGKVIAVEAIHQVLPDTSAATKCTSQMDVLMMTQIPGGKEFFSSLATEAGFRGIRFECFVCNFWVMELFK
>Morol36514S17161_MOROL
MGEEQEEETFAYAMHLVLGSVLRMAMQAAIDLGILEIIAKVGGGAKLSAAEITAQMPACRNPGAPMMVDRLLRLLASHGVVACSVVNSERLYSLAPVCRYFVRNEDGLSSQLKEAVLEGVLPFDRVHGVQMFEYPGLDPRFNQAFNVAMSNQTTIVMKRILESYKGFKQVKQLVDVGGSLGVNLNAITTKYPHIKGINFDLPHVIQQAPFYPGVEHIGGDMFQSVPKGDAIFMKWILHDWSDEHCLKLLKNCYSAIPEDGKVIVVEAILDIMPDTFTAAVSIFLKWTCL
>Morol36514S17080_MOROL
MDKEQDESFACAMQLALGSVLPMAMAAAVELGIFEVIGTGAKLSATEIAARMPACRNPGAPMMLDRILGLLANYSVLACSVFDKERLYSLTPVSKYFINNEDGVSLSPLMALVHDKMPFQSWFQLKEAVLEGGIPFDRVHGVHIFEYARLDARFNQLLNMAMFNYTTIVTKRILEHYNGFEQLKQLVDVGGGLGVTLKAITSKYPSIRGINFDLPHVIQHAEMYPGVEHVSGDMFESVPKGDAIFMKGILHDWDDEHCLKLLKNCHSATPDDGKVIVVDAILQDIPDTSAAMKCASQMDMLMMARVPGGKERTREEFMSLATKAGFSGIRFQCSVCNCTVMEFFK
MQLASSSVLPMVLKTAMELGVLEIIRRAGPGALLSPSEIAYSILTCSLTTNEQDIQVLRIYCLAPVAKYFPQSQDGGSLVPILNLIQDKNTVLERRHQFNRTYGMSGMEYVGKDARLRGMFQGFGRDSNFLFMEEILKTCKGFDDVKLVVDVGSGDGSVLNVIVVDVGSGDGSVLNVIVSANPTVKGINYDLPAVVGKSPPYPGMLTGCPFRKKRN
>Morol36224S13220_MOROL
MAGSIRGSQNEVTGRTHPNSSCILQIQELCRALSLTTPAQGTKMSDLQRINDHDRVDEDQELGKQAIRLANAVVLPMVLKSALELGLVDTIYAAGDGAFLSPVEIASRLPSRNPQTPVLLDRVLRLLASYSVLRCRLRNGDNGDVERLYGAGPISRFLVKDQDSGSVGPLFLLHHDKVFMESWYHLNDVILEGGIPFNRAYGMTAFEYPGTDQRFNRVFNQAMSSHTTLIMRKILDVYQGFEGLNLLVDVGGGIGVTLNLITSKYPHIKGVNYDLPHVLADAPSYPGVEHVGGDMFVSVPKGDAIFMKWILHDWSDEHCLKLLKNCWEALPNTGKVIIVESILPMVPESTVSSNIVFEQDLFMLAQNPGGKERTQKEFEGLAVTSGFLGCEVICSAYNSWVMEFHKRADP
>Morol36224S13221_MOROL
MSDLQRINDHDRVDEDQELGKQAIRLANAVVLPMVLKSALELGLVDTIYAAGDGAFLSPVEIASRLPSRNPQAPVLLDRVLRLLASYSVLRCRLRNGDNGDVERLYGTGPISRFLVKNQDSGSVGPLFLLLHDKVFMESWYHLNDVILEGGIPFNRAYGMTAFEYPGTDQRFNRVFNQAMSSHTTLIMRKILDVYQGFEGLNLLVDVGGGIGVTLNLITSKYPHIRGVNYDLPHVLADAPSYPGVEHVGGDMFVSVPKGDAIFMKWILHDWSDEHCLKLLKNCWEALPNTGKVIIVESILPMVPESTVSSNIVFEQDLFMLAQNPGGKERTQKEFEGLAVTSGFLGCEVICTAYNSWVMEFHERADP
>Morol36248S13692_MOROL
MGSTGETQITPTQVSDEEANLFAMQLASASVLPMVLKSAIELDLLEIMAKAGPGAFLSPTYIASQLHTKNPDAPVMLDRMLRLLASYSVLTCSLRSLPDGRAERLYGLGPVCKFLTKNEDGVSLSALCLMNQDKVLMESWYHLKDAVLEGGIPFNRAYGMSAFEYHGTDPRFNKVFNEGMSNHSTITMKKILEIYIGFGGLSSVVDVGGGTGASLSMIVSKYPTIRGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKLLRNCYEALPNNGKVIIAESILPVAPDPSLLTKLVVHVDCIMLAHNPGGKERTEKEFEALAKGAGFQGFQVVCSAFGSYIMEFLKNV
>Morol36447S16461_MOROL
MICPSRRGPLSKVSKGQPPVQSPDYISGVATLEIYRDQPVAAKGNRRKLGSERAMEEESGERRIEARLRIMELANMISVPMSLNAVVRLNVADAIWQGGANIPLSTSEILARILPPSSAATADPENLQRVLRMLTSYGVFEEHLMASDGFQRKYSLTDVGKTLVTDPEGLSYAPYVLQHHQDALMRAWPLVHEAVLDPTSEPFVKANGEPAYVHYGKDPKMNVLMQKAMSGVSVPFMKAILECYDGFDGVEQLVDVGGSAGDCLRIILQKHPTVREGINYDLPEVVAKAPPIPGVKHVGGNMFESIPSGDAIFMKWVLTTWTDSECKKIMENCYKALPVGGKLIACEPVLPLQSDDSHRTRALLEGDIFVMTIYKAKGMHRTEEEFKQLGLSAGFPRFKALYFDNFYTVLEFQK
>Morol36514S04780_MOROL
MKEKQEEALANAMQLVLASVLPIHGNASGHRSWILRLLVSHSVLACSVINQERFYSLTPVSEYFVCNKDGVSLGALMPLTHDKIYLESWSQLKDAVLDGGIPFNRVHGMYSFECPAYDSRFNQTTIVIKRILEIYKGFEQLKQLVDVGGDLGVNLKAITTKYPHIRGINFDLPHVIGHPLSYPDDGKVIAVEAIHQVLPDTSAATKCTSQMDVLMMTQIPGGKEFFSSLATEAGFRGIRFECFVCNFWVMELFK
>Morol36514S17161_MOROL
MGEEQEEETFAYAMHLVLGSVLRMAMQAAIDLGILEIIAKVGGGAKLSAAEITAQMPACRNPGAPMMVDRLLRLLASHGVVACSVVNSERLYSLAPVCRYFVRNEDGLSSQLKEAVLEGVLPFDRVHGVQMFEYPGLDPRFNQAFNVAMSNQTTIVMKRILESYKGFKQVKQLVDVGGSLGVNLNAITTKYPHIKGINFDLPHVIQQAPFYPGVEHIGGDMFQSVPKGDAIFMKWILHDWSDEHCLKLLKNCYSAIPEDGKVIVVEAILDIMPDTFTAAVSIFLKWTCL
>Morol36514S17080_MOROL
MDKEQDESFACAMQLALGSVLPMAMAAAVELGIFEVIGTGAKLSATEIAARMPACRNPGAPMMLDRILGLLANYSVLACSVFDKERLYSLTPVSKYFINNEDGVSLSPLMALVHDKMPFQSWFQLKEAVLEGGIPFDRVHGVHIFEYARLDARFNQLLNMAMFNYTTIVTKRILEHYNGFEQLKQLVDVGGGLGVTLKAITSKYPSIRGINFDLPHVIQHAEMYPGVEHVSGDMFESVPKGDAIFMKGILHDWDDEHCLKLLKNCHSATPDDGKVIVVDAILQDIPDTSAAMKCASQMDMLMMARVPGGKERTREEFMSLATKAGFSGIRFQCSVCNCTVMEFFK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University