Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Moringa oleifera
Species name
Horseradish tree (Moringa oleifera) is a species of eudicot in the family Moringaceae (horseradish tree family).
Species info
Gene sequence info
Moringa_oleifera.HIDH.fa
Download
>Morol1316S00039_MOROL
MDPTDPDVAYDFSPMFRVYKDGRTERIMGTEIVPPSLDSKTNIESKDVLYSSEENLSVRLYIPKSTQPNQKLPVLVYIHGGAFVIETAFSPVYHSYLNTLVAEANLIAVSVDYRRAPEHPVPIPYDDSWTALKWVASHFDGNRPEDWLNSHADFGKVFLAGDSAGANIAHHMAMRVGREKPEGINVVGIVMVHPYFWGIEPVGDEEKDPDKRSKVEALWRVESPNASGCDDPLLNVTADGSSLARLGCSRVLVCVAEKDILRYRGFDYYEKLGKSGWGGVVEIMVAEGEQHVFHLFNPRVENATLMLKRTAALVNQ
>Morol8222S04989_MOROL
MAVEPNVVSARLFLPKLTNPSQKLPLLIYFHGGAFCVSSPFTAKYHKYVNTIVGEANVIAVSVDYRLAPEHPIPAAYEDSWAALRWVFSHKNKDGPEPWLNEHADFGRVFLGGESAGANIAHHLAIHYGEPGFELGVELLGIALVHPFFWGSEPIGSEATDPDRKALVDKLWPFLCPSNPNNDDPRVNPFAADAPDLAGLQCRRMLMCVAEKDAMRDRGYLYYETLSKSGWMGVAEIMETEEEQHGFHLLDMEGERAKNLIKRLAAFYNRDMSPLV
>Morol25874S00165_MOROL
MASPTECTDPDVALDFSPLLRVYKDGRVERFVGTEVVPPSLDPKTNVESKDVLYSPEENLSVRLYRPKSTQPNQKLPVLVYIHGGAFIIETAFSPVYHNYLNSLVAEANLIAVSVDYRRAPEHPIPVPHDDSWTALKWIASHFDGNGPEDWLNRHADLGKVFLAGDSAGANIVHHIAIRAGREKPEGINIEGLILVHPYFWGTEPVGDEEKDPEKRSKFEALWRVASPNECGCDHPLLNVTADGSSLAGLVCSRVLVCVAEKDILRHRGFDYYEKLRKSGWGGAVEFMEAEGEQHVFHLYNPFLENAGFMLKRISAFINQ
>Morol35490S06440_MOROL
MASEDPADDIAHDFLPEFRAYKDGRIQRNFGTDRVLPAMDSPIGVSSKDVVIDPETGVSARVFIPSAAIVEPGQKLPLLVYYHGGGLFMGSPFCSTYVNYVASLVAKAKVVAVSVDYRLVPEHPVPAPYEDSWAALKWVVSHSGGSGPEPWLNEFTDFSRVFLAGDGAGANIAHNMAIQAASEGLSGAKLLGICLARS
>Morol36048S00726_MOROL
MGSVSKGVASELLPFLRIYKDGSIERLAGSPIVPPSPEDPETGVSSKDITVSHNPPISARVYLPKGVKPDQKLPILVYFHGGGFCIESAFSLLETKYMNGLVSEAEVLAISIEYRLAPEHPLPIAYDDCWVALQWVASHSGDHGTRDEPWLSIHGNFQQLFLGGDSAGANLVHNIAMRAGSQSLNGGVRILGAYLTHPYFCGSKPIGHEPTEERQKLLPLSVWNFLYPSVPGGVDNPILNPVAPGAPSLSGLGCSRLLVSVAEKDLLRDRGVAYYNAVKQSGWTGEAELVDVEGEDHAFHVVDHESNNATKLVKRLASFLLK
>Morol36088S01052_MOROL
MSIVAEAPGYLQVFSDGSVKRFAPEIAPASPKPCNGYSSKDVIIDPSKPITGRLFLPQTPGPFTELPLLVYFHGGGFCIGSTTWLGYHHFLADFSVRSKSIVLSVDYRLAPEHRLPIAYGDCYSSLEWLSHQVNTEPWLKQADLSRVFLSGDSAGGNIAHHVAIKAIREKVSHVDIKGLLLIHPYFGSEKRTENETADGATGDVKSNDMFWRLSIPERSNRDYYGCNFEMQEVSAAEWSEFPAAVVYVAGLDFLKERGVMYAAFLQNKGVKQVELVEAEGQSHVFHVFDPKCMATRMLQEQMSQFMKSY
>Morol36154S11197_MOROL
MGSLPYVVEDFRGVLQVLSDGTIFRSKNVDFSMPIINENSVIFKDALYSKIHNLYLRIYKPTSRTSQAKLPIIVYLHGGGFCLGSRLWPNCHNCCLRLASGLEALVMAPDYRLAPEHRLPAAMDDVETAMKWIQTQALSGDNVDAWLNSEDVDFDNVFVLGDSSGGNIAHHLAVWLRAGSHWLSPVRVRGYVLLAPFFGGVIRTKSEEGPSEALLSLEILDRFWRLSIPVGETRDNSFANPFGPLSPNLEAMSLDPMLVIAGGAELLKDRAKDYAERLKKMGKNIDYVEFKGKQHGFFTHDPYSEVGTEVLYLIQSFMFNNSK
>Morol36154S11198_MOROL
MGSLSHVVEDFMGVLQVLSDGTIFRSKNVDFSMPIINENSVIFKDSLFSKTHNLHLRIYKPTSKISPVKLPIVIYLHGGGFCLGSRLWPNCHNCCLRLASGLEALVMAPDHRLAPEHKLPAAMDDVETAMNWVQTQALSGDNGDAWLNSEDVDFDKVFVLGDSSGGNIAHHLAVRLGAGSPWLSPIRVRGYVLLAPFFGGVARTKSEEGPSEARLNLEILDRFWRLSIPAGETRDHPLANPFGPLSPSLEAMSLDPILVIAGGAELLKDRAKDYAERLKKIGKNIDYVEFKGKEHGFFTNDPYSEVGIEVLHLIKRFMFDNSK
>Morol33726S00393_MOROL
MAAISFDPRLNLQVGKNHHQHGVIFEEIEGLIRVYKDGYIERPPIIPMVPCTVALDHVVTARDVVIDKVTNLWARIYVPRCSSHKLPLLVYFHGGGFSVGSAAWSCYHEFLANLATKAGCVIMSINYRLAPENRLPAAYDDGFRALMWMKQQALNASSEQTWWSSQCNFSSLFLAGDSAGANIAYNVATKVGSNGASDSTLKPICLKGLILIQPFFGGEARTVSEKHTPQPAGSALTLSTSDTYWRLSLPIGANRDHPWCNPLANGAAKLRELRLPPTMVCISEMDILKDRNLEFCTMLANAGKKVETVMYKGVGHAFQILHNSQLSQIRLQEMMAHLKAFLNR
>Morol36320S03940_MOROL
MAATALDPSLSLQMGREPNKHGAVIEEIGGLVRVYKDGYVERPQIIPCVSSSLAPELGVTSRDIVISIFTNTWARFYVPRNHGTNLPLVVYFHGGGFSVGSASWSCYHEFLARLAAKAGCVIMSVDYRLAPENPLPAAYEDGLKALLWLKQQSVSGPNGDNWWCRHCNFSSVFLAGDSAGANIAYNVATRLGTNNEHQVMALKPLTLKGIILIQPFFGGEARTSSEKHMVQPPRSALSLAASDTYWRLALPRGCNRDHPWCNPTAKGSIKLAELRKLAAMVCISETDILRDRNLEFCAALARAGNRVEHVVYKGVGHAFQVLSKSQLSQTRTQEMMSHIKAFINQP
>Morol36358S15775_MOROL
MPQCTHLSVNYFFVALFFLFLLKLPILHYFFFIRGGDVCHTIATPPIDDSRHEVNECRGVLHVYNDGSIWQSSKPSFDVPVINDGSVLWEDVLFHPTYNFHLCLYKSASIPSLAKLPVFYYIHGEGFCIMIISGDSVGGNIAHNLVVRPWASSPKLDLVRVGVMCFLHHFSKDQKGIGLRQRVRKKLA
>Morol36418S04376_MOROL
MAVEPNVVSARLFLPKLTNPSQKLPLLIYFHGGAFCVSSPFTAKYHKYVNTIVGEANVIAVSVDYRLAPEHPIPAAYEDSWAALRWVFSHKNKDGPEPWLNEHADFGRVFLGGESAGANIAHHLAIHYGEPGFELGVELLGIALVHPFFWGSEPIGSEATDPDRKALVDKLWPFLCPSNPNNDDPRVNPFAADAPDLAGLQCRRMLMCVAEKDAMRDRGYLYYETLSKSGWMGVAEIMETEEEQHGFHLLDMEGERAKNLIKRLAAFYNRDMSPLV
>Morol36418S04375_MOROL
MGSNKKEVSLELFPYLRVFKDGTIERIAGTEVVPAGFDPETCVLSKDVVVTPETGVSARLYRPDWTKKDQKLPVVVYFHGGAFCIATPSEPKYHVCLNKLAAEANAIIVSVDYRLAPEHPLPAAYDDSWAALQWVATGDGGHDPWLKDYADFNQVFLMGDSAGANIAHHMALRVKDSDSDPGQELKIRGIGMIHPYFWGADPIGSEVTDRLRKEMVDGWWKFVCPTEKGCDDPLINPFVDGAPSLSHLACERVLIVVAEKDILRDRGKLYYEKLGKSEWKGKAEIVETEGKDHVFHIFDPNCEEAKDLIRSLAAFIDKWMSLVR
MDPTDPDVAYDFSPMFRVYKDGRTERIMGTEIVPPSLDSKTNIESKDVLYSSEENLSVRLYIPKSTQPNQKLPVLVYIHGGAFVIETAFSPVYHSYLNTLVAEANLIAVSVDYRRAPEHPVPIPYDDSWTALKWVASHFDGNRPEDWLNSHADFGKVFLAGDSAGANIAHHMAMRVGREKPEGINVVGIVMVHPYFWGIEPVGDEEKDPDKRSKVEALWRVESPNASGCDDPLLNVTADGSSLARLGCSRVLVCVAEKDILRYRGFDYYEKLGKSGWGGVVEIMVAEGEQHVFHLFNPRVENATLMLKRTAALVNQ
>Morol8222S04989_MOROL
MAVEPNVVSARLFLPKLTNPSQKLPLLIYFHGGAFCVSSPFTAKYHKYVNTIVGEANVIAVSVDYRLAPEHPIPAAYEDSWAALRWVFSHKNKDGPEPWLNEHADFGRVFLGGESAGANIAHHLAIHYGEPGFELGVELLGIALVHPFFWGSEPIGSEATDPDRKALVDKLWPFLCPSNPNNDDPRVNPFAADAPDLAGLQCRRMLMCVAEKDAMRDRGYLYYETLSKSGWMGVAEIMETEEEQHGFHLLDMEGERAKNLIKRLAAFYNRDMSPLV
>Morol25874S00165_MOROL
MASPTECTDPDVALDFSPLLRVYKDGRVERFVGTEVVPPSLDPKTNVESKDVLYSPEENLSVRLYRPKSTQPNQKLPVLVYIHGGAFIIETAFSPVYHNYLNSLVAEANLIAVSVDYRRAPEHPIPVPHDDSWTALKWIASHFDGNGPEDWLNRHADLGKVFLAGDSAGANIVHHIAIRAGREKPEGINIEGLILVHPYFWGTEPVGDEEKDPEKRSKFEALWRVASPNECGCDHPLLNVTADGSSLAGLVCSRVLVCVAEKDILRHRGFDYYEKLRKSGWGGAVEFMEAEGEQHVFHLYNPFLENAGFMLKRISAFINQ
>Morol35490S06440_MOROL
MASEDPADDIAHDFLPEFRAYKDGRIQRNFGTDRVLPAMDSPIGVSSKDVVIDPETGVSARVFIPSAAIVEPGQKLPLLVYYHGGGLFMGSPFCSTYVNYVASLVAKAKVVAVSVDYRLVPEHPVPAPYEDSWAALKWVVSHSGGSGPEPWLNEFTDFSRVFLAGDGAGANIAHNMAIQAASEGLSGAKLLGICLARS
>Morol36048S00726_MOROL
MGSVSKGVASELLPFLRIYKDGSIERLAGSPIVPPSPEDPETGVSSKDITVSHNPPISARVYLPKGVKPDQKLPILVYFHGGGFCIESAFSLLETKYMNGLVSEAEVLAISIEYRLAPEHPLPIAYDDCWVALQWVASHSGDHGTRDEPWLSIHGNFQQLFLGGDSAGANLVHNIAMRAGSQSLNGGVRILGAYLTHPYFCGSKPIGHEPTEERQKLLPLSVWNFLYPSVPGGVDNPILNPVAPGAPSLSGLGCSRLLVSVAEKDLLRDRGVAYYNAVKQSGWTGEAELVDVEGEDHAFHVVDHESNNATKLVKRLASFLLK
>Morol36088S01052_MOROL
MSIVAEAPGYLQVFSDGSVKRFAPEIAPASPKPCNGYSSKDVIIDPSKPITGRLFLPQTPGPFTELPLLVYFHGGGFCIGSTTWLGYHHFLADFSVRSKSIVLSVDYRLAPEHRLPIAYGDCYSSLEWLSHQVNTEPWLKQADLSRVFLSGDSAGGNIAHHVAIKAIREKVSHVDIKGLLLIHPYFGSEKRTENETADGATGDVKSNDMFWRLSIPERSNRDYYGCNFEMQEVSAAEWSEFPAAVVYVAGLDFLKERGVMYAAFLQNKGVKQVELVEAEGQSHVFHVFDPKCMATRMLQEQMSQFMKSY
>Morol36154S11197_MOROL
MGSLPYVVEDFRGVLQVLSDGTIFRSKNVDFSMPIINENSVIFKDALYSKIHNLYLRIYKPTSRTSQAKLPIIVYLHGGGFCLGSRLWPNCHNCCLRLASGLEALVMAPDYRLAPEHRLPAAMDDVETAMKWIQTQALSGDNVDAWLNSEDVDFDNVFVLGDSSGGNIAHHLAVWLRAGSHWLSPVRVRGYVLLAPFFGGVIRTKSEEGPSEALLSLEILDRFWRLSIPVGETRDNSFANPFGPLSPNLEAMSLDPMLVIAGGAELLKDRAKDYAERLKKMGKNIDYVEFKGKQHGFFTHDPYSEVGTEVLYLIQSFMFNNSK
>Morol36154S11198_MOROL
MGSLSHVVEDFMGVLQVLSDGTIFRSKNVDFSMPIINENSVIFKDSLFSKTHNLHLRIYKPTSKISPVKLPIVIYLHGGGFCLGSRLWPNCHNCCLRLASGLEALVMAPDHRLAPEHKLPAAMDDVETAMNWVQTQALSGDNGDAWLNSEDVDFDKVFVLGDSSGGNIAHHLAVRLGAGSPWLSPIRVRGYVLLAPFFGGVARTKSEEGPSEARLNLEILDRFWRLSIPAGETRDHPLANPFGPLSPSLEAMSLDPILVIAGGAELLKDRAKDYAERLKKIGKNIDYVEFKGKEHGFFTNDPYSEVGIEVLHLIKRFMFDNSK
>Morol33726S00393_MOROL
MAAISFDPRLNLQVGKNHHQHGVIFEEIEGLIRVYKDGYIERPPIIPMVPCTVALDHVVTARDVVIDKVTNLWARIYVPRCSSHKLPLLVYFHGGGFSVGSAAWSCYHEFLANLATKAGCVIMSINYRLAPENRLPAAYDDGFRALMWMKQQALNASSEQTWWSSQCNFSSLFLAGDSAGANIAYNVATKVGSNGASDSTLKPICLKGLILIQPFFGGEARTVSEKHTPQPAGSALTLSTSDTYWRLSLPIGANRDHPWCNPLANGAAKLRELRLPPTMVCISEMDILKDRNLEFCTMLANAGKKVETVMYKGVGHAFQILHNSQLSQIRLQEMMAHLKAFLNR
>Morol36320S03940_MOROL
MAATALDPSLSLQMGREPNKHGAVIEEIGGLVRVYKDGYVERPQIIPCVSSSLAPELGVTSRDIVISIFTNTWARFYVPRNHGTNLPLVVYFHGGGFSVGSASWSCYHEFLARLAAKAGCVIMSVDYRLAPENPLPAAYEDGLKALLWLKQQSVSGPNGDNWWCRHCNFSSVFLAGDSAGANIAYNVATRLGTNNEHQVMALKPLTLKGIILIQPFFGGEARTSSEKHMVQPPRSALSLAASDTYWRLALPRGCNRDHPWCNPTAKGSIKLAELRKLAAMVCISETDILRDRNLEFCAALARAGNRVEHVVYKGVGHAFQVLSKSQLSQTRTQEMMSHIKAFINQP
>Morol36358S15775_MOROL
MPQCTHLSVNYFFVALFFLFLLKLPILHYFFFIRGGDVCHTIATPPIDDSRHEVNECRGVLHVYNDGSIWQSSKPSFDVPVINDGSVLWEDVLFHPTYNFHLCLYKSASIPSLAKLPVFYYIHGEGFCIMIISGDSVGGNIAHNLVVRPWASSPKLDLVRVGVMCFLHHFSKDQKGIGLRQRVRKKLA
>Morol36418S04376_MOROL
MAVEPNVVSARLFLPKLTNPSQKLPLLIYFHGGAFCVSSPFTAKYHKYVNTIVGEANVIAVSVDYRLAPEHPIPAAYEDSWAALRWVFSHKNKDGPEPWLNEHADFGRVFLGGESAGANIAHHLAIHYGEPGFELGVELLGIALVHPFFWGSEPIGSEATDPDRKALVDKLWPFLCPSNPNNDDPRVNPFAADAPDLAGLQCRRMLMCVAEKDAMRDRGYLYYETLSKSGWMGVAEIMETEEEQHGFHLLDMEGERAKNLIKRLAAFYNRDMSPLV
>Morol36418S04375_MOROL
MGSNKKEVSLELFPYLRVFKDGTIERIAGTEVVPAGFDPETCVLSKDVVVTPETGVSARLYRPDWTKKDQKLPVVVYFHGGAFCIATPSEPKYHVCLNKLAAEANAIIVSVDYRLAPEHPLPAAYDDSWAALQWVATGDGGHDPWLKDYADFNQVFLMGDSAGANIAHHMALRVKDSDSDPGQELKIRGIGMIHPYFWGADPIGSEVTDRLRKEMVDGWWKFVCPTEKGCDDPLINPFVDGAPSLSHLACERVLIVVAEKDILRDRGKLYYEKLGKSEWKGKAEIVETEGKDHVFHIFDPNCEEAKDLIRSLAAFIDKWMSLVR
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University