Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Moringa oleifera
Species name
Horseradish tree (Moringa oleifera) is a species of eudicot in the family Moringaceae (horseradish tree family).
Species info
Gene sequence info
Moringa_oleifera.4CL.fa
Download
>Morol36119S09767_MOROL
MTDLDLDVKFGAKLTIEMVLLACHSGHRSVSLKGVNTMGTHSPYSANDDEHIFRSRYPAVAVPDDVTLPEFVLQDAELYSDHVAFVEAVSGRAYTYGEVVRDTRRFAKALRSLGLRKGHVVILVLPNVAEYGIVALGIMAAGGVFSGANPTAHASEIKKQAEAADAKLIVTDGTNYEKVKNLGLPVILLGEERIQGAMNWEELLQAGDRAGNNLKIEKIDQTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVGPEMVGQVTTLGLIPFFHIYGITGICCSTLRNKGKVVVMSRFDLRTFLNALITQGVTFAPIVPPIILNLVKNPIVEEFDLSKLKLRAIMTAAAPLAPELLTAFEKKFPGVQVQEAYGLTEHSCITLTHGDPAKDHGIAKKNSVGFILPNLEIKFIDPDTGRSLPKNMPGEICVRSQCVMQGYYNNKEETSRTIDENGWLHTGDIGYIDEDGDIFIVDRIKELIKYKGFQVAPAEIEAILLTHPSVEDAAVVPLPDEEAGEIPVACVVMNPNAKDSEEDIISFVASNVAYYKKVRVVHFVNAIPKSPSGKIMRRLVKDMMTEKIQTTLNTETNLSK
>Morol36222S03114_MOROL
MISVASIDPQTSEISAPVSPQEKPSSEIEHIFKSKLPDIPISNHLSLHTYSFENLSSCSDKPCLIVGSSGKTYSFAETHLISRKVAAGLSNLGIKKGDVIMILLQNSVEFVFSFMGASMIGAVSTMANPFYTQAEIFKQINISGAKLVITQAQYVDKLRDTEKENHPRIGEDFKVITTDDPPENCLHFSVLSQADENHIPKPSIDPDDPVALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLKQDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGRLLQLIQTHKVSVAAVVPPLVLALAKNPMVAQFDLTSIRVVLSGAAPLGKELEEALRSRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGACGTVVRNAELKVIHPETGCSLGRNQPGEICIRGSQIMKEYLNDPEATARTIDVEGWLHTGDIGYVDEDDEVPPAELEALLLSHPFIADAAVVPQKDEVAGEVPVAFVVRSNGFELSEDEVKEYIAKQVVFYKRLHKVQFVHAIPKSPSGKILRKDLRAKLTTPSPLP
>Morol36402S04296_MOROL
MAPHDQGTLLITTPQEDIIFRSKLPDIYIPKHLPLHHYCFQNISSVESRPCLINGPTGDVYTYAEVELTARRIASGLNKLGIQQGQVIMLLLPNSPEFVLSFLGASYRGAIATAANPFFTPAEIAKQAKASGTKLIITQACYVDKVKEFADDKDDLKIMCTDSAPAGCLHFSELSQADEKDLPHVEINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEIGSLLELIQKYKVTIAPVVPPVVLAIAKSADTDKYDLSSVRMLKSGAAPLGKDLEDAVRAKFPNAKFGQGYGMTEAGPVLAMGLGFAKEPFDVKSGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGNQIMKGYLNDPEATARTIDKQGWLHTGDIGYIDDDDELYIVDRLKELIKYKGFQVAPAELEALLIGHPDIKDAAVVAMKDEVAGELPVAFVVISSDSHITEDDIKKYVSKQVVFYKKIHRVFFLDAIPKAPSGKILRKDLRAKLAAANQI
>Morol36403S16081_MOROL
MEAKRDNLDEFIFRSKLPDIYIPNHLPLHTYCFENISQFKDRPCLINGPDGKIYSYADVELTARKVASGLNKLGVEQGDVIMLLLQNSPEFVFAFLGASFRGAISTTANPFYTPAEVAKQGTASKTKLIITQSVYVDKVKDFAKEAGIKVVTVDAPPEDCLHFSELTQADENEIPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQVDGENPNLYFHEKDVILCVLPLFHIYALNAALLCSLRVGAAILIMKKFEIVTLLELVQKHKVTIAPFVPPIVLAIAKSPDVDKYDLSSIRMVMSGAAPMGKELEDAVRTKLPKAKLGQGYGMTEAGPVLSMCLAFAKEPFPIKSGACGTVLRNAEMKIVDPETGSSLPRNHSGEICIRGSQIMKGYLNDPESTARTIDKDGWLHTGDVGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVPMIDEAAGEVPVAFVVRSNGSKISDDDIKQYIAKQVVFYKRLNRVFFTDTIPKAPSGKILRKDLRARLAADLPK
>Morol36515S04817_MOROL
MEKSGYGRDGIFRSLRPPLVLPKDPNLSAVSFLFRNASSYPDKPALFDADSSESLSFSQFKCTVAKLSHGFLNLGIKKKDVVLIFAPNSIQFPLCFLSVAAIGAIATTANPLYTVTELSKQIKDSNPKLVITVPELWDKVKDFNLPTVFLGSKESKQVPRTESNARNLHFHDLIELSGSVSDFPVVHVKQTDIAALLYSSGTTGISKGVILTHKNFIAASLMVTMDQQLSGDMHRVFLCVLPMFHVFGLSIILYAQLQIGNAVVSMKKFDFELLLRNVEKYSVTHLWLVPPVILALAKQSAVKKYDLSSLKQIGSGAAPLGKDLMEECAKNFTQAVTMQVVSILEFLIAPIISTLKLSVENPTVGKRNTGSAGVLASGIESQIVGKDTQKPLPPNQLGEIWVRGPNMMLGYLNNPQATKLTIDRKGWVHTGDLGYFNEDGHLFVVDRIKELIKYKGFQVAPAELEGLLVSHSEILDAVVIPFPDAEAGEVPIAFVVRSPNSSLTEEAVQNFIAKQVAPYKRLRRVTFVNSVPKSASGKILRRELIEKVRSKI
MTDLDLDVKFGAKLTIEMVLLACHSGHRSVSLKGVNTMGTHSPYSANDDEHIFRSRYPAVAVPDDVTLPEFVLQDAELYSDHVAFVEAVSGRAYTYGEVVRDTRRFAKALRSLGLRKGHVVILVLPNVAEYGIVALGIMAAGGVFSGANPTAHASEIKKQAEAADAKLIVTDGTNYEKVKNLGLPVILLGEERIQGAMNWEELLQAGDRAGNNLKIEKIDQTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVGPEMVGQVTTLGLIPFFHIYGITGICCSTLRNKGKVVVMSRFDLRTFLNALITQGVTFAPIVPPIILNLVKNPIVEEFDLSKLKLRAIMTAAAPLAPELLTAFEKKFPGVQVQEAYGLTEHSCITLTHGDPAKDHGIAKKNSVGFILPNLEIKFIDPDTGRSLPKNMPGEICVRSQCVMQGYYNNKEETSRTIDENGWLHTGDIGYIDEDGDIFIVDRIKELIKYKGFQVAPAEIEAILLTHPSVEDAAVVPLPDEEAGEIPVACVVMNPNAKDSEEDIISFVASNVAYYKKVRVVHFVNAIPKSPSGKIMRRLVKDMMTEKIQTTLNTETNLSK
>Morol36222S03114_MOROL
MISVASIDPQTSEISAPVSPQEKPSSEIEHIFKSKLPDIPISNHLSLHTYSFENLSSCSDKPCLIVGSSGKTYSFAETHLISRKVAAGLSNLGIKKGDVIMILLQNSVEFVFSFMGASMIGAVSTMANPFYTQAEIFKQINISGAKLVITQAQYVDKLRDTEKENHPRIGEDFKVITTDDPPENCLHFSVLSQADENHIPKPSIDPDDPVALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLKQDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGRLLQLIQTHKVSVAAVVPPLVLALAKNPMVAQFDLTSIRVVLSGAAPLGKELEEALRSRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGACGTVVRNAELKVIHPETGCSLGRNQPGEICIRGSQIMKEYLNDPEATARTIDVEGWLHTGDIGYVDEDDEVPPAELEALLLSHPFIADAAVVPQKDEVAGEVPVAFVVRSNGFELSEDEVKEYIAKQVVFYKRLHKVQFVHAIPKSPSGKILRKDLRAKLTTPSPLP
>Morol36402S04296_MOROL
MAPHDQGTLLITTPQEDIIFRSKLPDIYIPKHLPLHHYCFQNISSVESRPCLINGPTGDVYTYAEVELTARRIASGLNKLGIQQGQVIMLLLPNSPEFVLSFLGASYRGAIATAANPFFTPAEIAKQAKASGTKLIITQACYVDKVKEFADDKDDLKIMCTDSAPAGCLHFSELSQADEKDLPHVEINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEIGSLLELIQKYKVTIAPVVPPVVLAIAKSADTDKYDLSSVRMLKSGAAPLGKDLEDAVRAKFPNAKFGQGYGMTEAGPVLAMGLGFAKEPFDVKSGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGNQIMKGYLNDPEATARTIDKQGWLHTGDIGYIDDDDELYIVDRLKELIKYKGFQVAPAELEALLIGHPDIKDAAVVAMKDEVAGELPVAFVVISSDSHITEDDIKKYVSKQVVFYKKIHRVFFLDAIPKAPSGKILRKDLRAKLAAANQI
>Morol36403S16081_MOROL
MEAKRDNLDEFIFRSKLPDIYIPNHLPLHTYCFENISQFKDRPCLINGPDGKIYSYADVELTARKVASGLNKLGVEQGDVIMLLLQNSPEFVFAFLGASFRGAISTTANPFYTPAEVAKQGTASKTKLIITQSVYVDKVKDFAKEAGIKVVTVDAPPEDCLHFSELTQADENEIPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQVDGENPNLYFHEKDVILCVLPLFHIYALNAALLCSLRVGAAILIMKKFEIVTLLELVQKHKVTIAPFVPPIVLAIAKSPDVDKYDLSSIRMVMSGAAPMGKELEDAVRTKLPKAKLGQGYGMTEAGPVLSMCLAFAKEPFPIKSGACGTVLRNAEMKIVDPETGSSLPRNHSGEICIRGSQIMKGYLNDPESTARTIDKDGWLHTGDVGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVPMIDEAAGEVPVAFVVRSNGSKISDDDIKQYIAKQVVFYKRLNRVFFTDTIPKAPSGKILRKDLRARLAADLPK
>Morol36515S04817_MOROL
MEKSGYGRDGIFRSLRPPLVLPKDPNLSAVSFLFRNASSYPDKPALFDADSSESLSFSQFKCTVAKLSHGFLNLGIKKKDVVLIFAPNSIQFPLCFLSVAAIGAIATTANPLYTVTELSKQIKDSNPKLVITVPELWDKVKDFNLPTVFLGSKESKQVPRTESNARNLHFHDLIELSGSVSDFPVVHVKQTDIAALLYSSGTTGISKGVILTHKNFIAASLMVTMDQQLSGDMHRVFLCVLPMFHVFGLSIILYAQLQIGNAVVSMKKFDFELLLRNVEKYSVTHLWLVPPVILALAKQSAVKKYDLSSLKQIGSGAAPLGKDLMEECAKNFTQAVTMQVVSILEFLIAPIISTLKLSVENPTVGKRNTGSAGVLASGIESQIVGKDTQKPLPPNQLGEIWVRGPNMMLGYLNNPQATKLTIDRKGWVHTGDLGYFNEDGHLFVVDRIKELIKYKGFQVAPAELEGLLVSHSEILDAVVIPFPDAEAGEVPIAFVVRSPNSSLTEEAVQNFIAKQVAPYKRLRRVTFVNSVPKSASGKILRRELIEKVRSKI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University