Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Mimulus guttatus
Species name
Spotted monkey flower (Erythranthe guttata) is a species of eudicot in the family Phrymaceae.
Species info
Gene sequence info
Mimulus_guttatus.OMT.fa
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>MgTOL.H2236.1.v5.0
MQWIFHDWTDEECIKILEKCKEAITSGDNNIGGKVIIVEIVVDDQKEDQKATETQLLFDMLMMIEVTGKERTEKEWANLFFSAGFSNYKITPVLGLRSIIEVFP
>MgTOL.H2183.1.v5.0
MKFSELVDSLPIHKTKSHYIYRLMRLLVHSEFFVKIDISDGEEQEERYWLTPASRLLLHDAHLTVAPFVLAILDPIFTKPWEYTSEWLANEHPPSPFETANGGATFWDVAGREERVSNLFNEAMSSDTRLMARVLVNECKHVFDGIESVVDVGGNTGTLAKAILDEFPNMRCIVLDLSHNLVGLEGSKNLTYVSGDMFEAIPSADVVFLKVCILHDWNDEDCVRILKKCRDAIFGGKVIIIDMVMNIYEADNKAMEDELFFDMAMMVYQNGKERNEKEWAKLFFDSGFTSYKITPAFGVRSLIEVYP
>MgTOL.H2182.1.v5.0
MALLNEELSREQLLHAQAHVWNHIYAFIKSNSLKSALQLGIPDIIHNHGKPMKLSELVDALPIHKAKSHYIYRLMRVLVHFEFFVKVDIPYDEEKEEEEEEEEEEEHYYWLTPASRLLLLDDARLITIAPLMLLVLDPISTKPWEYTSEWLANEHLASPFETAHGKTYWEVMGQDPRMKNLFNEAMSSDTRLMARVLANECKHVFDGIESVVDVGGNTGTLAKAILDEFPNMKCIVLDLPHNLVGLEGSKNLTYVGGDMFEAIPPADAILLKKYYILIKIWHISFNFKCNGRRNEI
>MgTOL.H2179.1.v5.0
MKYNINTNETNYSIGKMALLKSNNDQELSRDQLLHAQTHIWNHIFTFMKSISLKSAIQLGIPDIIHNHGKPIKLSELVDALPVSKSKSHYIHRLMRILVHSEFFIKDEEERYWLTPASRLLLKEGHFTVAPLVLLILDPILTKPWDYTMEWLADDRSVSPFETANGGTNFWEVAGREPRVSNLFNEVMSSDTRLVARVLIDDCKHVFDGIESLVDVGGNTGTLAKAILDALPKLKCIVLDLPHNLVGLEGSNNLTFVGGDMFEAIPRGDAILLKWILHDWNDEDCVKILKKCKDAIPDKDKGGGKLIIIDMVMNTYEGDDNKAMEDQLFFDMAMMAYLNGKERSEKEWAKLFFDAGFTDYKITPAFGVRSLIEVYP
>MgTOL.N3074.1.v5.0
MFQQEEEEEQALVDVWELAFGYINFKVVQSAVELEIPDILENHGVPMSLSELSSAVDCPSETLYRIMRFLIHHGIFKKLSQTSGIHYASTPLSRRMTKAHFSSFMLIQGPTPGIRGVTPEGLRNGASRPDHFEDDDDTEMLAEAVECQAKAAMSAVIDNYPEGFEGIASLVDVADHRRRGAALAVLAKAFPQIRGITFDLPENVAKGTTLADDVPKAEAVLLMWILHEMSDEVCIEILKKCKEAVPRETGKVIIVEAIVVDEEGGGGGKGNEFAGAHLSLDMVMMAVTANGKERTHNEWAYLLSAAGFTTHKLTTNIKTIVSVIEAFP
>MgTOL.N0312.1.v5.0
MGLDEEARARAEVWNYAFGYINCRVVKCAVELEIPDIVRKHAGGGGSGGGPISLSELSSAVGVPTEPLHRIMRFLIHHRIFKTSPPPPHAESSSDDEVHYAATPLSGLLTRDNLAPFMLLQGTPPGPNRGITPEALRTGRRPDLKSVNGEDTWTVPDFGYHMKVFTDSMAAHARVATQAIIDNFPEGFKGIETLLDVGGRHGMALSMLVKAFPWLRGTVLDLPEIADHAPPLEGIHFVGGSMFENIPNSDAVMLMWILHDWSDEACIDILKKCKDAVPKDTGKVMIVEAVIDEDGEGDEYAGARLSLDMVMMSVMVKGKERTYKEWAYLLDEAGFSRHNVVNIKTVVSVIEAFP
>MgTOL.N1357.1.v5.0
MEAKSIQKTNEEEEAQAQVDIWEYVFGFTPMAVVKCAVELKIADILEIHGGSMTHTDLSTALNCSPSILHRIMRYLIHRGFFKQNQESSEICYTQTALSRLLMTKNNKANSMADFILLESSHVMLSPWLKLSSRVSGNGDHNSPFEAVHGKDVWAYASSNPGHSSLINGAMASHARVAMSAIVDRCPEAFEGVGCLVDVGGGDGTALRTLMKSCPLISRGINFDLPHVVSVAPEFDGVENVGGDMFQVVPKADAAFLMWVLHDWSDEECIVILRKCREAIPEGTGKVIIAEAVIGEKDEVDKYNDVRLALDMVMLAHTEKGKERSIEEWEYVVKSAGFSSFTVKHIHSIVSVIQAYP
>MgTOL.N3073.1.v5.0
MVMTGEEAQAAADVWKFIYGLIKCKAIKCALELGIPDILESNGGAPFSLADLSSATGCHTTESLHRLMRFLIHHRIFKKATTTNTTGGGGVVHYTHTPLSRLFTRGRMRPLVLLRGAPATTWGGLCAEALRTGKHPDVAGSFEGDEDTWTDPDLGHHLDVFTDAMESHTRVVAAAMVDNYGALGFDGVGTLVDVGGRHGMALSILVKAFPWVSGITFDLPDIVAQAPPRDGVRFVGGSMFDYVPKADAVMLMWILHDWSDEACIDILKKCKEAVVEESGKVIIVEAVIDEDDDEDEYASARLSLDMLMMDAMPKGKERTYKEWVHLLDAAGFTTHHVINIKTDVSLIEAFP
>MgTOL.N0313.1.v5.0
MGFDEKEARARAQVWDYVFGYINPRVVKTAVELEIPDIVEKHGGPISLPELSSAVGVPTESLHRIMRFLIFNGIFKKAPPPPHGEVSGEVHYYAPTPLSGLMTKENLAAFMLLQGMPTGFNAGITPAALRTGKRPDLKAVKGEDTWTDPAHGNHMKLFTDSMEAHARVATQAMVDNFPAGFEGIESLVDVGGRHGMALSMLVKAFPWVSGTVLDLPEVVAKAPPRGGVHFVGGSMFEKVPNADAVMLMWVLHDWSDEMCIDILKKCKDAVPKDTGKVMIVEAVIDEDGEGDEYAGARLSLDMVMMAVNVKAKERTYKEWAFLLNQAGFTTHNLINIKTVVSLIQAFP
>MgTOL.N0311.1.v5.0
MGLDEEARARAEVWNYAFGYINCRVVKCARRGGPVSLSELSSAVGVPTEPLQRIMRFLIHHRIFKTSPPPPHAESSSDEVHYAATPLSGLLTRDILRYSCYLGTPPGPNRGITPEALRTGSRPDLKSVNGEDTWTVPDFGYHMKVFTDSMAAHARVATQAIIDNFTEGFKGIETLLDVGGRHGMALSMLVRAFPWLRGTVLDLPEIVDHAPPLEGIHFVGGSMFENIPNSDAVMLMWILHDWSDEACIDILKKCKDAVPKDTGKVMIVEAVIDEDGEGDEYAGARLSLDMVMMSVMVKGKERTYKEWAYLLEEAGFSRHNVVNIKTVVSVIEAFP
MQWIFHDWTDEECIKILEKCKEAITSGDNNIGGKVIIVEIVVDDQKEDQKATETQLLFDMLMMIEVTGKERTEKEWANLFFSAGFSNYKITPVLGLRSIIEVFP
>MgTOL.H2183.1.v5.0
MKFSELVDSLPIHKTKSHYIYRLMRLLVHSEFFVKIDISDGEEQEERYWLTPASRLLLHDAHLTVAPFVLAILDPIFTKPWEYTSEWLANEHPPSPFETANGGATFWDVAGREERVSNLFNEAMSSDTRLMARVLVNECKHVFDGIESVVDVGGNTGTLAKAILDEFPNMRCIVLDLSHNLVGLEGSKNLTYVSGDMFEAIPSADVVFLKVCILHDWNDEDCVRILKKCRDAIFGGKVIIIDMVMNIYEADNKAMEDELFFDMAMMVYQNGKERNEKEWAKLFFDSGFTSYKITPAFGVRSLIEVYP
>MgTOL.H2182.1.v5.0
MALLNEELSREQLLHAQAHVWNHIYAFIKSNSLKSALQLGIPDIIHNHGKPMKLSELVDALPIHKAKSHYIYRLMRVLVHFEFFVKVDIPYDEEKEEEEEEEEEEEHYYWLTPASRLLLLDDARLITIAPLMLLVLDPISTKPWEYTSEWLANEHLASPFETAHGKTYWEVMGQDPRMKNLFNEAMSSDTRLMARVLANECKHVFDGIESVVDVGGNTGTLAKAILDEFPNMKCIVLDLPHNLVGLEGSKNLTYVGGDMFEAIPPADAILLKKYYILIKIWHISFNFKCNGRRNEI
>MgTOL.H2179.1.v5.0
MKYNINTNETNYSIGKMALLKSNNDQELSRDQLLHAQTHIWNHIFTFMKSISLKSAIQLGIPDIIHNHGKPIKLSELVDALPVSKSKSHYIHRLMRILVHSEFFIKDEEERYWLTPASRLLLKEGHFTVAPLVLLILDPILTKPWDYTMEWLADDRSVSPFETANGGTNFWEVAGREPRVSNLFNEVMSSDTRLVARVLIDDCKHVFDGIESLVDVGGNTGTLAKAILDALPKLKCIVLDLPHNLVGLEGSNNLTFVGGDMFEAIPRGDAILLKWILHDWNDEDCVKILKKCKDAIPDKDKGGGKLIIIDMVMNTYEGDDNKAMEDQLFFDMAMMAYLNGKERSEKEWAKLFFDAGFTDYKITPAFGVRSLIEVYP
>MgTOL.N3074.1.v5.0
MFQQEEEEEQALVDVWELAFGYINFKVVQSAVELEIPDILENHGVPMSLSELSSAVDCPSETLYRIMRFLIHHGIFKKLSQTSGIHYASTPLSRRMTKAHFSSFMLIQGPTPGIRGVTPEGLRNGASRPDHFEDDDDTEMLAEAVECQAKAAMSAVIDNYPEGFEGIASLVDVADHRRRGAALAVLAKAFPQIRGITFDLPENVAKGTTLADDVPKAEAVLLMWILHEMSDEVCIEILKKCKEAVPRETGKVIIVEAIVVDEEGGGGGKGNEFAGAHLSLDMVMMAVTANGKERTHNEWAYLLSAAGFTTHKLTTNIKTIVSVIEAFP
>MgTOL.N0312.1.v5.0
MGLDEEARARAEVWNYAFGYINCRVVKCAVELEIPDIVRKHAGGGGSGGGPISLSELSSAVGVPTEPLHRIMRFLIHHRIFKTSPPPPHAESSSDDEVHYAATPLSGLLTRDNLAPFMLLQGTPPGPNRGITPEALRTGRRPDLKSVNGEDTWTVPDFGYHMKVFTDSMAAHARVATQAIIDNFPEGFKGIETLLDVGGRHGMALSMLVKAFPWLRGTVLDLPEIADHAPPLEGIHFVGGSMFENIPNSDAVMLMWILHDWSDEACIDILKKCKDAVPKDTGKVMIVEAVIDEDGEGDEYAGARLSLDMVMMSVMVKGKERTYKEWAYLLDEAGFSRHNVVNIKTVVSVIEAFP
>MgTOL.N1357.1.v5.0
MEAKSIQKTNEEEEAQAQVDIWEYVFGFTPMAVVKCAVELKIADILEIHGGSMTHTDLSTALNCSPSILHRIMRYLIHRGFFKQNQESSEICYTQTALSRLLMTKNNKANSMADFILLESSHVMLSPWLKLSSRVSGNGDHNSPFEAVHGKDVWAYASSNPGHSSLINGAMASHARVAMSAIVDRCPEAFEGVGCLVDVGGGDGTALRTLMKSCPLISRGINFDLPHVVSVAPEFDGVENVGGDMFQVVPKADAAFLMWVLHDWSDEECIVILRKCREAIPEGTGKVIIAEAVIGEKDEVDKYNDVRLALDMVMLAHTEKGKERSIEEWEYVVKSAGFSSFTVKHIHSIVSVIQAYP
>MgTOL.N3073.1.v5.0
MVMTGEEAQAAADVWKFIYGLIKCKAIKCALELGIPDILESNGGAPFSLADLSSATGCHTTESLHRLMRFLIHHRIFKKATTTNTTGGGGVVHYTHTPLSRLFTRGRMRPLVLLRGAPATTWGGLCAEALRTGKHPDVAGSFEGDEDTWTDPDLGHHLDVFTDAMESHTRVVAAAMVDNYGALGFDGVGTLVDVGGRHGMALSILVKAFPWVSGITFDLPDIVAQAPPRDGVRFVGGSMFDYVPKADAVMLMWILHDWSDEACIDILKKCKEAVVEESGKVIIVEAVIDEDDDEDEYASARLSLDMLMMDAMPKGKERTYKEWVHLLDAAGFTTHHVINIKTDVSLIEAFP
>MgTOL.N0313.1.v5.0
MGFDEKEARARAQVWDYVFGYINPRVVKTAVELEIPDIVEKHGGPISLPELSSAVGVPTESLHRIMRFLIFNGIFKKAPPPPHGEVSGEVHYYAPTPLSGLMTKENLAAFMLLQGMPTGFNAGITPAALRTGKRPDLKAVKGEDTWTDPAHGNHMKLFTDSMEAHARVATQAMVDNFPAGFEGIESLVDVGGRHGMALSMLVKAFPWVSGTVLDLPEVVAKAPPRGGVHFVGGSMFEKVPNADAVMLMWVLHDWSDEMCIDILKKCKDAVPKDTGKVMIVEAVIDEDGEGDEYAGARLSLDMVMMAVNVKAKERTYKEWAFLLNQAGFTTHNLINIKTVVSLIQAFP
>MgTOL.N0311.1.v5.0
MGLDEEARARAEVWNYAFGYINCRVVKCARRGGPVSLSELSSAVGVPTEPLQRIMRFLIHHRIFKTSPPPPHAESSSDEVHYAATPLSGLLTRDILRYSCYLGTPPGPNRGITPEALRTGSRPDLKSVNGEDTWTVPDFGYHMKVFTDSMAAHARVATQAIIDNFTEGFKGIETLLDVGGRHGMALSMLVRAFPWLRGTVLDLPEIVDHAPPLEGIHFVGGSMFENIPNSDAVMLMWILHDWSDEACIDILKKCKDAVPKDTGKVMIVEAVIDEDGEGDEYAGARLSLDMVMMSVMVKGKERTYKEWAYLLEEAGFSRHNVVNIKTVVSVIEAFP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University