Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Mimulus guttatus
Species name
Spotted monkey flower (Erythranthe guttata) is a species of eudicot in the family Phrymaceae.
Species info
Gene sequence info
Mimulus_guttatus.ROMT.fa
Download
>MgTOL.H2236.1.v5.0
MQWIFHDWTDEECIKILEKCKEAITSGDNNIGGKVIIVEIVVDDQKEDQKATETQLLFDMLMMIEVTGKERTEKEWANLFFSAGFSNYKITPVLGLRSIIEVFP
>MgTOL.H2183.1.v5.0
MKFSELVDSLPIHKTKSHYIYRLMRLLVHSEFFVKIDISDGEEQEERYWLTPASRLLLHDAHLTVAPFVLAILDPIFTKPWEYTSEWLANEHPPSPFETANGGATFWDVAGREERVSNLFNEAMSSDTRLMARVLVNECKHVFDGIESVVDVGGNTGTLAKAILDEFPNMRCIVLDLSHNLVGLEGSKNLTYVSGDMFEAIPSADVVFLKVCILHDWNDEDCVRILKKCRDAIFGGKVIIIDMVMNIYEADNKAMEDELFFDMAMMVYQNGKERNEKEWAKLFFDSGFTSYKITPAFGVRSLIEVYP
>MgTOL.H2182.1.v5.0
MALLNEELSREQLLHAQAHVWNHIYAFIKSNSLKSALQLGIPDIIHNHGKPMKLSELVDALPIHKAKSHYIYRLMRVLVHFEFFVKVDIPYDEEKEEEEEEEEEEEHYYWLTPASRLLLLDDARLITIAPLMLLVLDPISTKPWEYTSEWLANEHLASPFETAHGKTYWEVMGQDPRMKNLFNEAMSSDTRLMARVLANECKHVFDGIESVVDVGGNTGTLAKAILDEFPNMKCIVLDLPHNLVGLEGSKNLTYVGGDMFEAIPPADAILLKKYYILIKIWHISFNFKCNGRRNEI
>MgTOL.H2179.1.v5.0
MKYNINTNETNYSIGKMALLKSNNDQELSRDQLLHAQTHIWNHIFTFMKSISLKSAIQLGIPDIIHNHGKPIKLSELVDALPVSKSKSHYIHRLMRILVHSEFFIKDEEERYWLTPASRLLLKEGHFTVAPLVLLILDPILTKPWDYTMEWLADDRSVSPFETANGGTNFWEVAGREPRVSNLFNEVMSSDTRLVARVLIDDCKHVFDGIESLVDVGGNTGTLAKAILDALPKLKCIVLDLPHNLVGLEGSNNLTFVGGDMFEAIPRGDAILLKWILHDWNDEDCVKILKKCKDAIPDKDKGGGKLIIIDMVMNTYEGDDNKAMEDQLFFDMAMMAYLNGKERSEKEWAKLFFDAGFTDYKITPAFGVRSLIEVYP
MQWIFHDWTDEECIKILEKCKEAITSGDNNIGGKVIIVEIVVDDQKEDQKATETQLLFDMLMMIEVTGKERTEKEWANLFFSAGFSNYKITPVLGLRSIIEVFP
>MgTOL.H2183.1.v5.0
MKFSELVDSLPIHKTKSHYIYRLMRLLVHSEFFVKIDISDGEEQEERYWLTPASRLLLHDAHLTVAPFVLAILDPIFTKPWEYTSEWLANEHPPSPFETANGGATFWDVAGREERVSNLFNEAMSSDTRLMARVLVNECKHVFDGIESVVDVGGNTGTLAKAILDEFPNMRCIVLDLSHNLVGLEGSKNLTYVSGDMFEAIPSADVVFLKVCILHDWNDEDCVRILKKCRDAIFGGKVIIIDMVMNIYEADNKAMEDELFFDMAMMVYQNGKERNEKEWAKLFFDSGFTSYKITPAFGVRSLIEVYP
>MgTOL.H2182.1.v5.0
MALLNEELSREQLLHAQAHVWNHIYAFIKSNSLKSALQLGIPDIIHNHGKPMKLSELVDALPIHKAKSHYIYRLMRVLVHFEFFVKVDIPYDEEKEEEEEEEEEEEHYYWLTPASRLLLLDDARLITIAPLMLLVLDPISTKPWEYTSEWLANEHLASPFETAHGKTYWEVMGQDPRMKNLFNEAMSSDTRLMARVLANECKHVFDGIESVVDVGGNTGTLAKAILDEFPNMKCIVLDLPHNLVGLEGSKNLTYVGGDMFEAIPPADAILLKKYYILIKIWHISFNFKCNGRRNEI
>MgTOL.H2179.1.v5.0
MKYNINTNETNYSIGKMALLKSNNDQELSRDQLLHAQTHIWNHIFTFMKSISLKSAIQLGIPDIIHNHGKPIKLSELVDALPVSKSKSHYIHRLMRILVHSEFFIKDEEERYWLTPASRLLLKEGHFTVAPLVLLILDPILTKPWDYTMEWLADDRSVSPFETANGGTNFWEVAGREPRVSNLFNEVMSSDTRLVARVLIDDCKHVFDGIESLVDVGGNTGTLAKAILDALPKLKCIVLDLPHNLVGLEGSNNLTFVGGDMFEAIPRGDAILLKWILHDWNDEDCVKILKKCKDAIPDKDKGGGKLIIIDMVMNTYEGDDNKAMEDQLFFDMAMMAYLNGKERSEKEWAKLFFDAGFTDYKITPAFGVRSLIEVYP
Sheng jun & Dong yang Teams, Yunnan agriculture University