Enzyme

Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.

OMT

Enzyme

Xanthohumol 4-O-methyltransferase

Enzyme name

EC:2.1.1.338

Entry

Transferases;Transferring one-carbon groups;Methyltransferases

Class

S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase

Sysname

S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]

Reaction

S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]

Product

Species information

Anacardium occidentale

Species name

Cashew (Anacardium occidentale) is a species of eudicot in the family Anacardiaceae (sumac family).

Species info

Gene sequence info

Anacardium_occidentale.OMT.fa

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>Anaoc.0003s1281.1.v0.9
MEATKIQVKRDEQEENKKEEAKAQVEIWSYIFGFVKVAVVKCAIELGIAEAIENNGCPMTLSELSATLNCSPSNLHRIMRFLVHYQIFKEISTSQNSIAFEQTPVSRRLLKQGKNSMAAFVLLESSPVMLAPWHGLSGRVLANGTSAFDSAHGKDVWAYAAEDAVHSKLINDAMACNAKVAVPAVIEECPEVFDGIGRLVDVGGGNGTALGLLVEAFPWITGINFDLPHVVCDNERSDRVEQVGGDMFQSVPMADAAFFMQVLHDWDDDECIQILKNCREAIPKDKGKVIIVETIIDEEERDELEYVRLMLDMVMMAHTSKGKERTLKEWDHLLRQAGFSRYNVKPIHAVQSVIEAFP
>Anaoc.0006s0724.1.v0.9
MRMLARKGVFAAHRPSEGGDTTYGLTPVSKWLLHDSELSLAPKILMENNLWQLAPWHYLSQCVKQGGSAFKKAHGCEMWDFASQNTEFNKLFNDALACTTKIVMRPLLSQYKDGFNNVQSLVDVGGGTGGELNEILKAYPYIKGINFDLPHVVAMAPEYDRVLNVGGNMFDAIPNADVVFMKWILHDWSDEACVKILKNCRKAIPEKTGKVVLVEIVLQEDGNNMFGNMDLVFDLLMFAHTAGGKERTKQEWKKLLEEGGFPRYNIINFPALPSIIEAYPR
>Anaoc.0006s0723.1.v0.9
MANSLEVETLLEGQAEVWQYMFGFVDSMVLKSAVELRLADIIHSYGGPISLSQIASSIKSLHILSSLVLLVCHHLN
>Anaoc.0006s0722.1.v0.9
MEVADTSEESMRGQVEIWQHMFSFADSMALKCAVELRIADIINSHGGPVTLPQLAASIGSPSPGISYLSRIMRMLVRKKIFAAHHDLNGEGETLYGLTHSSRWLLRDSELSLAPMILMENHPLLRLPGTVLANTTHGKHIWDFALQNPEFNKLFNDGLACTSKIIARAIISGYKDGFISINGSLVDVGGGTGNLIAEIVKSCPHVKGINFDLPHVISTAPKFDGISHIEGDMFQAIPKADAVILKWVLHDWSDEDCVKILRNCRKAIPEKSGKVIIAEVVVRPDGNHLSDETGLAFDLLMIAHSSGGKERTEFEWKKILQEGGFPRYNIINIPAIPCIIEAFPE
>Anaoc.0007s1249.1.v0.9
MDPKRGEGGSELFRAQSHLYKHIFNYISSMSLKCAVQLGIPDTIHKHARPITLPELVSELEVHPAKTSDIFRLMRLLVQSGFFSTTTVLADNNQEEEAYVLTPSSKLLIKDESNCLSPFLLSMLDPAFLTPWHSLEGWFRGNELTVTPFERAHGVNFWDYGEQNPEFNYLFGQAMASDSQMANLVAQDCKPVFEGLDSLVDVGGGTGSFSRIISEVFPNMNCIVFDLPHIVANLPESKNLKFMGGDMFRSIPPANAFLFKLVFHAFNDEDCVKILKKCREAAAASKGKGGKVIIIDIVIDEKKDDPELIKAKLYFDMLMMVVVTGRERNEKEWERLFLEAGFNGYKITPLFGLRSLIEVYP
>Anaoc.0007s1250.1.v0.9
MDPMNGEGGSELFRAQAHLYKHIFNFISSMSLKCAVELGIPDIVHKHAQPITLSELVSALQIPPSKTGHVYRLMRMLVHTGFFSTTKVVNDTNQEEGEEAYVLTSSSMLLLKDEPNCLTPFVQSMISPVLLTPWHFLGDWFRGSELNAFERAYGINFVDYWEQNPEFSKLFGLGMACDSQMGNLVIKDCKPIFEGLGSLVDVGGGTGSFARIISEEFPGIKCTVLDLPHVVANLPETQNLKFIGGNMFQSIPPADAYLFKWVFHGLGDEDCVKILTKCREGIATKQGKVIIIDIVIDEKKDELKETKLFFDMLMMVAVTGKERTEKEWERLFLEAGFTHYKIIPMFGLKSLIEVYL
>Anaoc.0014s0631.1.v0.9
MYLVNGEHDSELLQAQAHVWNQIFSFINSMSLNCAIQLCIPDAIHNHGKPMTLTQLLTAIPVHPSKTIFVYRLMRILTHSGFFTVTKAGDNYEEEEYALTSSSKLLLKDNPLSVRSFVTAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKFWEYAGREPEVNHFFNEAMACDARLVTSMVIDKCEHVFKGLKSLIDVGGGTGNVAEAIVQAFPHLECIVFDLPHVVSDMQSHGNLKYAGGNMFDVVPSADAVLLKWILHDWNDEECVKILKKCKEAITSNGKTGKVIIIDMVFEKKEGDDKSTETQLFFDMLMMVLVKGKERNEKEWANLFLEAGFTRYKINPILGLRSLIEVYP
>Anaoc.0014s0635.1.v0.9
MSSVNGGHDSELLRAQAHVWNQMFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPVHPTKKIFFYRLMRLLTHSGFFTLKKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAFLNPVLITPWNHLSTWFQIGDSNPFVVAHGMNLWEYAGREPQFNNFFNEAMACDARLVSSVVIDKCEHVFKGLKSLVDVGGGTGIVAQAIVQAFRHLECTVFDLPHVVSDMQSHGNLKYAGGNMFDAVPSADAALLKWILHDWNDEECVKILKNCKEAITSNGKMGKVIIIDMVVEKKKGMINRLNRNSYLTC
>Anaoc.0014s0633.1.v0.9
MSLVNGEHNSELLRAQAHVWNQIFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAMLNPVLITPWNLLSTWFQNGDSNPFVMAHGMHLWEYAESEPQFNKIFNETMACDAQLVTSVVIDKCEHVFKGLKSLVDVGGGTGNVAQAIVQAFPHLECTVFDLPHVVSDMQSHGNLKYAGGNMFDAVPSADAALLKWILHDWNDEECVKILKKCKEAITSNGKMGKVIIIDMVFEEKEGDDKSIETQLFFDMLMMVLVKGKERDEREWANLFLRLVSLAIK
>Anaoc.0014s0630.1.v0.9
MSLNCAIQLCIPDAIHSHGKPMSLTQILTTLPVHPSKTIFVHRLMRILTHSGFFTLTKAGDNYEEEEYALTSSSKLLLKHNPLSVRPFLMAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKLWEYAGREPQVNHFFNEAMACDARFVASVVIDKCNHVFKGLKSLIDVGGGTGNVAKAIAQAFPHLECTVFDLPHVVSDMQSHGNLKYAGEACLMPFLLQMQSYLSGYCMIGMMKNA
>Anaoc.0014s0634.1.v0.9
MYLVNGEHDSELIQAQAHVWNQIFSFINSMSLNCAIQLCIPDAIHNHGKPMTLTQLLTALPVRPSKIIFVYRLKGILTHSGFFTVTKAGDNYEEEEYALTSSSKLLLKDNPLSVRPFVTAILNPVLTTPWNHLGTCSRDEILGVRWPMACDARLVTIMVIGKCEHVFKGLKWLIDVGGGTGNVAKGIVQAFPHLNALHGNLKYAGGNMFDVVPSADAVLLKQCVKILKKCKEAITSNGKMGKVIIIDMVFEKKEANDKSIET
>Anaoc.0598s0008.1.v0.9
SLPRSTIYRPQSLIQFSKTNIGDVFGNGGHDNELLRAEAHVWTQIFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPVHPTKTIFFYRLMRLLTHSGFFTLKKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAMLNPVLITPWNHLSTWFQIGDSNPFVVAHGMNLWEYAGREPQFNNYFNEAMACDARLVSSVVIDKCEHVFKGLKSLVDVGGGTGNVAQAIVQAFPHLECTVFDLPHVVSNMQSHGNLKYAGGNMFEAVPSADAALLKWILHDWNDEECVKILKNCKEAITSNGKMGKVIIIDMVVEKKKGMINRLNRNSYLTW
>Anaoc.0598s0012.1.v0.9
MSLNCAIQLCIPDAIHSHGKPMSLTQILTTLPVHPSKTIFVHRLMRILTHSGFFTLTKAGDNYEEEEYALTSSSKLLLKHNPLSVRPFLMAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKLWEYAGREPQVNHFFNEAMACDARFVASVVIDKCNHVFKGLKSLIDVGGGTGNVAKAIAQAFPHLECTVFDLPHVVSDMQSHGNLKYAGEWILHDWNDEECVKILKKCKEAITSNGKTGKVIIIDIVFDKKEGDDKSTETQLFFDMLMMVLVTGKERNEKEWANLFLEAGFTHYKINPILGLRSLIEVYP
>Anaoc.0598s0011.1.v0.9
MYLVNGEHDSELLQAQAHVWNQIFSFINSMSLNCAIQLCIPDAIHNHGKPMTLTQLLTAIPVHPSKTIFVYRLMRILTHSGFFTVTKAGDNYEEEEYALTSSSKLLLKDNPLSVRSFVTAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKFWEYAGREPEVNHFFNEAMACDARLVTSMVIDKCEHVFKGLKSLIDVGGGTGNVAEAIVQAFPHLECIVFDLPHVVSDMQSHGNLKYAGGNMFDVVPSADAVLLKWILHDWNDEECVKILKKCKEAITSNGKTGKVIIIDMVFEKKEGDDKSTETQLFFDMLMMVLVKGKERNEKEWANLFLEAGFTRYKINPILGLRSLIEVYP
>Anaoc.0598s0010.1.v0.9
MSLVNGEHDKELLRAQAHVWNQIFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPVHPTKTIFFYRLMRILTHSGFFTLKKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAMLNPVLITPWNHLSTWFQNGDSNPFVVAHGMHLWEYAESEPQFNKIFNETMACDARLVTSVVIDKCEHVFKGLKSLVDVGGGTGNVAQAIVEAFPHLECTVFDLPHVVSDMQSHGNLKYAGGNMFDAVPSADAALLKWILHDWNDEECVKILKKCKEAITSNGKMGKVIIIDMVFEEKEGDDKSIETQLFFDMLMMVLVKGKERDEREWANLFLEAGFTRYKINPILGLRSLIEVYP

Gene tree

Gene tree

Sheng jun & Dong yang Teams, Yunnan agriculture University