Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Anacardium occidentale
Species name
Cashew (Anacardium occidentale) is a species of eudicot in the family Anacardiaceae (sumac family).
Species info
Gene sequence info
Anacardium_occidentale.ROMT.fa
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>Anaoc.0014s0631.1.v0.9
MYLVNGEHDSELLQAQAHVWNQIFSFINSMSLNCAIQLCIPDAIHNHGKPMTLTQLLTAIPVHPSKTIFVYRLMRILTHSGFFTVTKAGDNYEEEEYALTSSSKLLLKDNPLSVRSFVTAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKFWEYAGREPEVNHFFNEAMACDARLVTSMVIDKCEHVFKGLKSLIDVGGGTGNVAEAIVQAFPHLECIVFDLPHVVSDMQSHGNLKYAGGNMFDVVPSADAVLLKWILHDWNDEECVKILKKCKEAITSNGKTGKVIIIDMVFEKKEGDDKSTETQLFFDMLMMVLVKGKERNEKEWANLFLEAGFTRYKINPILGLRSLIEVYP
>Anaoc.0014s0632.1.v0.9
MYLVNGEHDSELLQAQAHVWNKIFSIINSIPFTMGMANSVLATPWNHLFTFKMAGREPQINHFFIQAIVCDARLVSSVVIGKCEHVFKGLKSLINVGGGTGNVAKAIDQAFPHLECTVFDLSRVISDMQNHGNLIYVGENMFDAVPSADAILSNYKMREDGIVIIVGMVFEKKQGNDKSTKKQFFFDTLMMVLVTSKKRDEKEWVNLFPKAGFARYKINPMLGIRFLIEVYP
>Anaoc.0014s0635.1.v0.9
MSSVNGGHDSELLRAQAHVWNQMFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPVHPTKKIFFYRLMRLLTHSGFFTLKKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAFLNPVLITPWNHLSTWFQIGDSNPFVVAHGMNLWEYAGREPQFNNFFNEAMACDARLVSSVVIDKCEHVFKGLKSLVDVGGGTGIVAQAIVQAFRHLECTVFDLPHVVSDMQSHGNLKYAGGNMFDAVPSADAALLKWILHDWNDEECVKILKNCKEAITSNGKMGKVIIIDMVVEKKKGMINRLNRNSYLTC
>Anaoc.0014s0633.1.v0.9
MSLVNGEHNSELLRAQAHVWNQIFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAMLNPVLITPWNLLSTWFQNGDSNPFVMAHGMHLWEYAESEPQFNKIFNETMACDAQLVTSVVIDKCEHVFKGLKSLVDVGGGTGNVAQAIVQAFPHLECTVFDLPHVVSDMQSHGNLKYAGGNMFDAVPSADAALLKWILHDWNDEECVKILKKCKEAITSNGKMGKVIIIDMVFEEKEGDDKSIETQLFFDMLMMVLVKGKERDEREWANLFLRLVSLAIK
>Anaoc.0014s0630.1.v0.9
MSLNCAIQLCIPDAIHSHGKPMSLTQILTTLPVHPSKTIFVHRLMRILTHSGFFTLTKAGDNYEEEEYALTSSSKLLLKHNPLSVRPFLMAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKLWEYAGREPQVNHFFNEAMACDARFVASVVIDKCNHVFKGLKSLIDVGGGTGNVAKAIAQAFPHLECTVFDLPHVVSDMQSHGNLKYAGEACLMPFLLQMQSYLSGYCMIGMMKNA
>Anaoc.0014s0634.1.v0.9
MYLVNGEHDSELIQAQAHVWNQIFSFINSMSLNCAIQLCIPDAIHNHGKPMTLTQLLTALPVRPSKIIFVYRLKGILTHSGFFTVTKAGDNYEEEEYALTSSSKLLLKDNPLSVRPFVTAILNPVLTTPWNHLGTCSRDEILGVRWPMACDARLVTIMVIGKCEHVFKGLKWLIDVGGGTGNVAKGIVQAFPHLNALHGNLKYAGGNMFDVVPSADAVLLKQCVKILKKCKEAITSNGKMGKVIIIDMVFEKKEANDKSIET
>Anaoc.0598s0008.1.v0.9
SLPRSTIYRPQSLIQFSKTNIGDVFGNGGHDNELLRAEAHVWTQIFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPVHPTKTIFFYRLMRLLTHSGFFTLKKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAMLNPVLITPWNHLSTWFQIGDSNPFVVAHGMNLWEYAGREPQFNNYFNEAMACDARLVSSVVIDKCEHVFKGLKSLVDVGGGTGNVAQAIVQAFPHLECTVFDLPHVVSNMQSHGNLKYAGGNMFEAVPSADAALLKWILHDWNDEECVKILKNCKEAITSNGKMGKVIIIDMVVEKKKGMINRLNRNSYLTW
>Anaoc.0598s0012.1.v0.9
MSLNCAIQLCIPDAIHSHGKPMSLTQILTTLPVHPSKTIFVHRLMRILTHSGFFTLTKAGDNYEEEEYALTSSSKLLLKHNPLSVRPFLMAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKLWEYAGREPQVNHFFNEAMACDARFVASVVIDKCNHVFKGLKSLIDVGGGTGNVAKAIAQAFPHLECTVFDLPHVVSDMQSHGNLKYAGEWILHDWNDEECVKILKKCKEAITSNGKTGKVIIIDIVFDKKEGDDKSTETQLFFDMLMMVLVTGKERNEKEWANLFLEAGFTHYKINPILGLRSLIEVYP
>Anaoc.0598s0011.1.v0.9
MYLVNGEHDSELLQAQAHVWNQIFSFINSMSLNCAIQLCIPDAIHNHGKPMTLTQLLTAIPVHPSKTIFVYRLMRILTHSGFFTVTKAGDNYEEEEYALTSSSKLLLKDNPLSVRSFVTAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKFWEYAGREPEVNHFFNEAMACDARLVTSMVIDKCEHVFKGLKSLIDVGGGTGNVAEAIVQAFPHLECIVFDLPHVVSDMQSHGNLKYAGGNMFDVVPSADAVLLKWILHDWNDEECVKILKKCKEAITSNGKTGKVIIIDMVFEKKEGDDKSTETQLFFDMLMMVLVKGKERNEKEWANLFLEAGFTRYKINPILGLRSLIEVYP
>Anaoc.0598s0010.1.v0.9
MSLVNGEHDKELLRAQAHVWNQIFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPVHPTKTIFFYRLMRILTHSGFFTLKKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAMLNPVLITPWNHLSTWFQNGDSNPFVVAHGMHLWEYAESEPQFNKIFNETMACDARLVTSVVIDKCEHVFKGLKSLVDVGGGTGNVAQAIVEAFPHLECTVFDLPHVVSDMQSHGNLKYAGGNMFDAVPSADAALLKWILHDWNDEECVKILKKCKEAITSNGKMGKVIIIDMVFEEKEGDDKSIETQLFFDMLMMVLVKGKERDEREWANLFLEAGFTRYKINPILGLRSLIEVYP
MYLVNGEHDSELLQAQAHVWNQIFSFINSMSLNCAIQLCIPDAIHNHGKPMTLTQLLTAIPVHPSKTIFVYRLMRILTHSGFFTVTKAGDNYEEEEYALTSSSKLLLKDNPLSVRSFVTAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKFWEYAGREPEVNHFFNEAMACDARLVTSMVIDKCEHVFKGLKSLIDVGGGTGNVAEAIVQAFPHLECIVFDLPHVVSDMQSHGNLKYAGGNMFDVVPSADAVLLKWILHDWNDEECVKILKKCKEAITSNGKTGKVIIIDMVFEKKEGDDKSTETQLFFDMLMMVLVKGKERNEKEWANLFLEAGFTRYKINPILGLRSLIEVYP
>Anaoc.0014s0632.1.v0.9
MYLVNGEHDSELLQAQAHVWNKIFSIINSIPFTMGMANSVLATPWNHLFTFKMAGREPQINHFFIQAIVCDARLVSSVVIGKCEHVFKGLKSLINVGGGTGNVAKAIDQAFPHLECTVFDLSRVISDMQNHGNLIYVGENMFDAVPSADAILSNYKMREDGIVIIVGMVFEKKQGNDKSTKKQFFFDTLMMVLVTSKKRDEKEWVNLFPKAGFARYKINPMLGIRFLIEVYP
>Anaoc.0014s0635.1.v0.9
MSSVNGGHDSELLRAQAHVWNQMFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPVHPTKKIFFYRLMRLLTHSGFFTLKKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAFLNPVLITPWNHLSTWFQIGDSNPFVVAHGMNLWEYAGREPQFNNFFNEAMACDARLVSSVVIDKCEHVFKGLKSLVDVGGGTGIVAQAIVQAFRHLECTVFDLPHVVSDMQSHGNLKYAGGNMFDAVPSADAALLKWILHDWNDEECVKILKNCKEAITSNGKMGKVIIIDMVVEKKKGMINRLNRNSYLTC
>Anaoc.0014s0633.1.v0.9
MSLVNGEHNSELLRAQAHVWNQIFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAMLNPVLITPWNLLSTWFQNGDSNPFVMAHGMHLWEYAESEPQFNKIFNETMACDAQLVTSVVIDKCEHVFKGLKSLVDVGGGTGNVAQAIVQAFPHLECTVFDLPHVVSDMQSHGNLKYAGGNMFDAVPSADAALLKWILHDWNDEECVKILKKCKEAITSNGKMGKVIIIDMVFEEKEGDDKSIETQLFFDMLMMVLVKGKERDEREWANLFLRLVSLAIK
>Anaoc.0014s0630.1.v0.9
MSLNCAIQLCIPDAIHSHGKPMSLTQILTTLPVHPSKTIFVHRLMRILTHSGFFTLTKAGDNYEEEEYALTSSSKLLLKHNPLSVRPFLMAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKLWEYAGREPQVNHFFNEAMACDARFVASVVIDKCNHVFKGLKSLIDVGGGTGNVAKAIAQAFPHLECTVFDLPHVVSDMQSHGNLKYAGEACLMPFLLQMQSYLSGYCMIGMMKNA
>Anaoc.0014s0634.1.v0.9
MYLVNGEHDSELIQAQAHVWNQIFSFINSMSLNCAIQLCIPDAIHNHGKPMTLTQLLTALPVRPSKIIFVYRLKGILTHSGFFTVTKAGDNYEEEEYALTSSSKLLLKDNPLSVRPFVTAILNPVLTTPWNHLGTCSRDEILGVRWPMACDARLVTIMVIGKCEHVFKGLKWLIDVGGGTGNVAKGIVQAFPHLNALHGNLKYAGGNMFDVVPSADAVLLKQCVKILKKCKEAITSNGKMGKVIIIDMVFEKKEANDKSIET
>Anaoc.0598s0008.1.v0.9
SLPRSTIYRPQSLIQFSKTNIGDVFGNGGHDNELLRAEAHVWTQIFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPVHPTKTIFFYRLMRLLTHSGFFTLKKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAMLNPVLITPWNHLSTWFQIGDSNPFVVAHGMNLWEYAGREPQFNNYFNEAMACDARLVSSVVIDKCEHVFKGLKSLVDVGGGTGNVAQAIVQAFPHLECTVFDLPHVVSNMQSHGNLKYAGGNMFEAVPSADAALLKWILHDWNDEECVKILKNCKEAITSNGKMGKVIIIDMVVEKKKGMINRLNRNSYLTW
>Anaoc.0598s0012.1.v0.9
MSLNCAIQLCIPDAIHSHGKPMSLTQILTTLPVHPSKTIFVHRLMRILTHSGFFTLTKAGDNYEEEEYALTSSSKLLLKHNPLSVRPFLMAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKLWEYAGREPQVNHFFNEAMACDARFVASVVIDKCNHVFKGLKSLIDVGGGTGNVAKAIAQAFPHLECTVFDLPHVVSDMQSHGNLKYAGEWILHDWNDEECVKILKKCKEAITSNGKTGKVIIIDIVFDKKEGDDKSTETQLFFDMLMMVLVTGKERNEKEWANLFLEAGFTHYKINPILGLRSLIEVYP
>Anaoc.0598s0011.1.v0.9
MYLVNGEHDSELLQAQAHVWNQIFSFINSMSLNCAIQLCIPDAIHNHGKPMTLTQLLTAIPVHPSKTIFVYRLMRILTHSGFFTVTKAGDNYEEEEYALTSSSKLLLKDNPLSVRSFVTAMLNPVLTTPWNHLGTWFQNGDSTPFDTAHGMKFWEYAGREPEVNHFFNEAMACDARLVTSMVIDKCEHVFKGLKSLIDVGGGTGNVAEAIVQAFPHLECIVFDLPHVVSDMQSHGNLKYAGGNMFDVVPSADAVLLKWILHDWNDEECVKILKKCKEAITSNGKTGKVIIIDMVFEKKEGDDKSTETQLFFDMLMMVLVKGKERNEKEWANLFLEAGFTRYKINPILGLRSLIEVYP
>Anaoc.0598s0010.1.v0.9
MSLVNGEHDKELLRAQAHVWNQIFSFINSMTLNCALQLCIPDAIHNHGKPMTLTQLLTALPVHPTKTIFFYRLMRILTHSGFFTLKKAGENDEEEEYALTSSSQLLLKDNPLSVRPFVMAMLNPVLITPWNHLSTWFQNGDSNPFVVAHGMHLWEYAESEPQFNKIFNETMACDARLVTSVVIDKCEHVFKGLKSLVDVGGGTGNVAQAIVEAFPHLECTVFDLPHVVSDMQSHGNLKYAGGNMFDAVPSADAALLKWILHDWNDEECVKILKKCKEAITSNGKMGKVIIIDMVFEEKEGDDKSIETQLFFDMLMMVLVKGKERDEREWANLFLEAGFTRYKINPILGLRSLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University