Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Microthlaspi erraticum
Species name
Microthlaspi erraticum is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Microthlaspi_erraticum.HIDH.fa
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>rna-MERR_LOCUS864
MDDDSEILYDYSPRFLIYKSGRIERLLPETFVPPSLTPTNGVVSKDAVYSPENDLSLRIYLPQNAVETGEEKKKKLPLLVYFHGGGFIMERPFTSTYHTFVTTAVKAADCIAVSVDYRRAPEHPIPTAYEDSWDAVKWIFTHVAGSGPEDWLNENADFNRVFLSGDSAGANIAHHMGVRAGKEKLKLDDDEFKIFGMALFCPYFWSKAPIDEHETTDEAARRGVEGMWEIASPNSENGVDDPLFNVVGSDDSDITGLACGRVLVMVAGDDIYVRQGWGYAGKLERSVWLGKVELDETEGEGHVFHITDPDSDNARRLVQIFADFLNDKTSWSI
>rna-MERR_LOCUS863
MDPDSEIAIDYSPRFRIFKSGRIERLVVRNFVSPSLNPTNGVISKDAVYSSENNLSLRIFLPQKAVETGEEKKKKKLPLLVYFHGGGFVMGSPFCTMYHPFVTSLVAAADCIAVSVEYRRAPEHPIPTAYEDSWEAIKWIFTHVAGSGPEDWLNENADFGRVFLAGDSAGANIAHHMGIRAGKEKLKLDGDDFKIFGMVLFHPYFWSKAPIDEHETKDVAERRHVEGKWEIASPNSENGVDDPWINVVGSDLTGLACGRVLVMVAGNDKFARQGLAYSAKLEKSGWQGKVEVEETKEEGHVFNIRVPDSDNARLVLQRFAEFLKRRDKLLNTHI
>rna-MERR_LOCUS866
MQQLMGSDSEILVDFSPRFLIYKNGRIERLVPEPFVPPSLNPTDGVVSKDAVYSPESDLSLRIYLPQKAIETGEEEKKKKKKLPLLVYFHGGGFIMERPFTSTYHTFLNSAVKAADCIAVSVDYRRAPEHPLPIAYEDSWDAIKWIFTHIAGSGPEDWLNENADFRRVFFSGDSAGANIAHHMGIRAGKEKLKDFKIFGMALFHPYFWSKDPIDEHETKEVAVRRQVEGMWEVASPNSENGVDDPWINVVGSDLTGLACGRVLVMVAENDKFARQGLAYAAKLEKSVWQGKVELVETKDEGHVFHIRVPDSDNARRLVQIFAEFLNEDETS
>rna-MERR_LOCUS5398
MAAISFSHNHQSSDNRRGVSHHHRHGPVVEEIDGLIKVFNDGCVERPPIVPTVSASVHPSAKVTAFDIKLSNDTSARVYIPDASVTLPLLVYFHGGGFCVGSAAWSCYHDFLTSLAVKARCVVVSVNYRLAPEHRLPAAYDDGVNVVSWLMKQQISNGGYSWVSKCNLSNVFLGGDSAGANIAYQVAVRITAGDKSVNTLNLKGVILIHPFFGGESRTSSERQQQHHSKSSALTLSASDTYWRLALPRGANRDHPWCNPLVSSSAGFLRAAKLPTTMMFMAELDILKDRNVEMCKVMRSHGKRVEGIVHGGVGHAFHILDNSPVARDRIHDMMCRLHNFIHPL
>rna-MERR_LOCUS33107
MGATTLTHMTTISPNNTNIHGPVVDEVEGLIRVYKDGHVERSELVPYVGPSLALELGVACSDVHIDKLTNVWARLYVPVVTKSSSVSKSKLPLLVYFHGGGFCVGSASWSCYHEFLAKLSARSRCLVMSVNYRLAPENLLPAAYEDGVNAILWLKKTRNDNLWAKLCDFSKIFLAGDSAGGNIANHVAARLAADDSLLKPLKIEGTILIQPFFGGEARTESERRVENNMKNSVLTLAASDAWWRMALPRGANRDHPYCKPVKVVTRTLVCVAEMDVLMDREIKMCDANEEVIKRVVYKGVGHAFQVLGKSQLAQTTTLDMLCHIDAFIHHYDPFN
>rna-MERR_LOCUS35271
MESTKKQVSLELFPWLIVYSDGTFERLAGTDFCPPGLDPETKVLSKDIIIDPKTGLSARIYRPDSIQPGQKLPLVLYFHGGAFLIASASFPSYHTSVNKLVGEANIIAVSVSYRLAPENPLPTAYEDSWNALQEINSGNEPWINDYADLDRFFLVGDSAGANISHHLAFRAKQSDQTVKIKGIGMIHPYFWGTQPIGSEITDEARKQMVDGWWRFVCPSEKGSEDPWINPFADGSPDLEGLGCERVLVTVAEKDILSERGKMYYERLVKSKWRGKAEIMETKEKDHVFHIFEPDCDEAMEMLRRLALFINQVEA
>rna-MERR_LOCUS35544
MESEIASEHLPFLRIYKDGRIERLTGTEIIPASLDATNDVVSKDVVYSPEHNLSVRLFLPHKSTELAAGDTKKLPLLIYIHGGAWIIESPFSPVYHNYLTEIVKSANCVAVSIQYRRAPEDPVPAAYEDSWSAIQWIFSHSGGSGPEDWINEYADFGRVFIAGDSAGGNISHHMAMRAGKEKLEPRIKGIAVVHPAFWGTDPVDEHDVQDRDMRSGIADVWEKIASPNSVNGTDDPLFNVLGSESDFSEMGCEKVLVAVAGKDVFVRQGLGYAAKLKKSGWGGDVEVVEEEEEGHCFHLLTPDSKNAPKFLKKLVEFIIG
>rna-MERR_LOCUS35541
MLRRITFSSSLRSPSLFFRFFRHLPRSNFSLSSSPTTVGISGSNLRRLSTPITLRCICSHSSSEIASEHPPFVRIYKDGRVERLSGTEIIPASLTPQNGVISKDVVYSPEHNLSVRLFLPQKATELPAGSKIPLLVYIHGGAWIIGSPFESIYHSFLTEVVKSANCLAVSIQYRRAPEDPIPAAYEDSWSAIQWIFSHSDGSGSVDWINKYADFDRVFLAGDSAGANMSHHMAIRAGKEKLKPRIKGTAIVHPAFWGKDPVDELDLQDKEKRSRIAEVWEKLASPNSVDGTDDPWFNVVGSGSDFSEMGCEKVLVAVAGKDVFVRQGLGYAEKLKKSGWEGEVEVVEDEDEDHCFHLLNSDSENAPKFMKKFVDFISG
>rna-MERR_LOCUS35540
MSSHSSSEIASEHPPYARIYKDGRVERMFRTDIIPASLTPQNGVVSKDVVYSPEHNLSVRLFLPQNATEIPAGKKIPLLVYIHGGAWIMGSPFAPIYHNLLSEVVKSANCLAVSIQYRRAPEDPIPAAYEDSWSAIQWIFSHSDGSGGPVDWINKYADFDRVFLAGDSAGANMSHHMAMRAGKEKLEPRIKGIAMVHPAFWGKDPIDELDLQDKEKRRQITELWEKLASPNSVDGTDDPLFNVVGSGSDFSEMGCEKVLVAVAGKDVFVRQGLGYAEKLKKSGWKGEVEVVEDEDEDHCFHLWTPDSENAPKLMKKFVDFISG
>rna-MERR_LOCUS35539
MESDLTIEPLPFIGTLKNGSTVESLRSNEVVPASLDLRNNVVSKDVVYSPELNLSVRLFLPHKKSTELAAGEKLPLLIYFHGGAYIMGSPFSPVSHNYLTEVVKASNCLAVSVQYRLAPEHPIPAAYEDSWSAIQWIFTHSDGFGEDAWINEHADFDRAFLAGDSAGANICHHMAIRAGEEKLNPRFKGVAMVHPGFWGKDPIDEKDVQDDGIRSGIAEVWETLASPNSVDGVNDPWLNVVGSGSDISGLGCETVLLAVAGKDVFGRQGLAYAEKLEKNGWRGDLKVVEEEDEGHCFHLRNPNSENASKLMKAFVEFIIHR
>rna-MERR_LOCUS37135
MESEIAFDMSPSFVVYKNGRLERLTGETIVPPSLNPQNGVISKDVVYSPEKNLSLRIYLPEKVVETDQKLPVLVYFHGGGFIFETAFSPIYHTFLTSAVAAAECLAISVDYRRAPEFPIPVPYEDSWDSLKWVFSYIDGTRPENWINKHADFGKVFLAGDSAGGNIAHHLAIRAEKEKLNPVISGMILIHPYFWGKTPIDELETRDERRRRKIDGSWEVASPNSEKGVDDPLFNVVGSESSDLSGLGCGRVLVMVAGYDIFVRQGFGYAAKLEKSGWGGEVEVMETKREGHAFHLKNPDTDNARQVVKKFAEFLKNKHYLISLL
>rna-MERR_LOCUS37136
MESEIAFDNSPNYRVYKNGRVERLSGETTVPPSLTPQNGVVSKDAVYSPEKNLSVRIFLPAKVVGTDQKLPVLVYFHGGGFVIHTAFSPTYHTFLTTTVAAADCLAISVDYRRAPEFPIPIPYEDSWNSLKWLFRHIDGTGSENWINKHADFAKVFLAGDSAGGNITHHLAMRAKREKLDHLVSGIVLIHPYFWGKNPIDEFETRDVKKRKRVEGCWAIVSPNSEKGVDDPLFNVVGSESSDLSGLGCGRVLVMVAGDDIYARQGLGYAVKLKKSGWEGEVELMEIKDEDHVHHLKNPITDNARQVVKKIAEFLNK
>rna-MERR_LOCUS43661
MDSEIAVDFSPVFKIYKSGRIERLMGEAKVPPSSTPQNGVVSKDVVYSPDDNLSVRIFLPEKAAETGDNKLPLLVYFHGGGFVIETAFSPTYHSFLTAAVSASDCVAVSVDYRRAPEHPIPASYDDSWTALKWVFTHIAGSGSEDWLNKHADFSKVYLAGDSAGANIAHHMAMRAAKEKLSSGLDESSSGISGMILVHPYFWSKTPLDEKETKDVLLRSKIEAFWKMASPNNKDGPDDPWLNVVQSESSDVSGLGCGKVLVMVAEKDALCRQGWGYAAKLEKSGWKGEVELVESEGEDHVFHLMKPDCDKALEAMHKFSGFIKGD
MDDDSEILYDYSPRFLIYKSGRIERLLPETFVPPSLTPTNGVVSKDAVYSPENDLSLRIYLPQNAVETGEEKKKKLPLLVYFHGGGFIMERPFTSTYHTFVTTAVKAADCIAVSVDYRRAPEHPIPTAYEDSWDAVKWIFTHVAGSGPEDWLNENADFNRVFLSGDSAGANIAHHMGVRAGKEKLKLDDDEFKIFGMALFCPYFWSKAPIDEHETTDEAARRGVEGMWEIASPNSENGVDDPLFNVVGSDDSDITGLACGRVLVMVAGDDIYVRQGWGYAGKLERSVWLGKVELDETEGEGHVFHITDPDSDNARRLVQIFADFLNDKTSWSI
>rna-MERR_LOCUS863
MDPDSEIAIDYSPRFRIFKSGRIERLVVRNFVSPSLNPTNGVISKDAVYSSENNLSLRIFLPQKAVETGEEKKKKKLPLLVYFHGGGFVMGSPFCTMYHPFVTSLVAAADCIAVSVEYRRAPEHPIPTAYEDSWEAIKWIFTHVAGSGPEDWLNENADFGRVFLAGDSAGANIAHHMGIRAGKEKLKLDGDDFKIFGMVLFHPYFWSKAPIDEHETKDVAERRHVEGKWEIASPNSENGVDDPWINVVGSDLTGLACGRVLVMVAGNDKFARQGLAYSAKLEKSGWQGKVEVEETKEEGHVFNIRVPDSDNARLVLQRFAEFLKRRDKLLNTHI
>rna-MERR_LOCUS866
MQQLMGSDSEILVDFSPRFLIYKNGRIERLVPEPFVPPSLNPTDGVVSKDAVYSPESDLSLRIYLPQKAIETGEEEKKKKKKLPLLVYFHGGGFIMERPFTSTYHTFLNSAVKAADCIAVSVDYRRAPEHPLPIAYEDSWDAIKWIFTHIAGSGPEDWLNENADFRRVFFSGDSAGANIAHHMGIRAGKEKLKDFKIFGMALFHPYFWSKDPIDEHETKEVAVRRQVEGMWEVASPNSENGVDDPWINVVGSDLTGLACGRVLVMVAENDKFARQGLAYAAKLEKSVWQGKVELVETKDEGHVFHIRVPDSDNARRLVQIFAEFLNEDETS
>rna-MERR_LOCUS5398
MAAISFSHNHQSSDNRRGVSHHHRHGPVVEEIDGLIKVFNDGCVERPPIVPTVSASVHPSAKVTAFDIKLSNDTSARVYIPDASVTLPLLVYFHGGGFCVGSAAWSCYHDFLTSLAVKARCVVVSVNYRLAPEHRLPAAYDDGVNVVSWLMKQQISNGGYSWVSKCNLSNVFLGGDSAGANIAYQVAVRITAGDKSVNTLNLKGVILIHPFFGGESRTSSERQQQHHSKSSALTLSASDTYWRLALPRGANRDHPWCNPLVSSSAGFLRAAKLPTTMMFMAELDILKDRNVEMCKVMRSHGKRVEGIVHGGVGHAFHILDNSPVARDRIHDMMCRLHNFIHPL
>rna-MERR_LOCUS33107
MGATTLTHMTTISPNNTNIHGPVVDEVEGLIRVYKDGHVERSELVPYVGPSLALELGVACSDVHIDKLTNVWARLYVPVVTKSSSVSKSKLPLLVYFHGGGFCVGSASWSCYHEFLAKLSARSRCLVMSVNYRLAPENLLPAAYEDGVNAILWLKKTRNDNLWAKLCDFSKIFLAGDSAGGNIANHVAARLAADDSLLKPLKIEGTILIQPFFGGEARTESERRVENNMKNSVLTLAASDAWWRMALPRGANRDHPYCKPVKVVTRTLVCVAEMDVLMDREIKMCDANEEVIKRVVYKGVGHAFQVLGKSQLAQTTTLDMLCHIDAFIHHYDPFN
>rna-MERR_LOCUS35271
MESTKKQVSLELFPWLIVYSDGTFERLAGTDFCPPGLDPETKVLSKDIIIDPKTGLSARIYRPDSIQPGQKLPLVLYFHGGAFLIASASFPSYHTSVNKLVGEANIIAVSVSYRLAPENPLPTAYEDSWNALQEINSGNEPWINDYADLDRFFLVGDSAGANISHHLAFRAKQSDQTVKIKGIGMIHPYFWGTQPIGSEITDEARKQMVDGWWRFVCPSEKGSEDPWINPFADGSPDLEGLGCERVLVTVAEKDILSERGKMYYERLVKSKWRGKAEIMETKEKDHVFHIFEPDCDEAMEMLRRLALFINQVEA
>rna-MERR_LOCUS35544
MESEIASEHLPFLRIYKDGRIERLTGTEIIPASLDATNDVVSKDVVYSPEHNLSVRLFLPHKSTELAAGDTKKLPLLIYIHGGAWIIESPFSPVYHNYLTEIVKSANCVAVSIQYRRAPEDPVPAAYEDSWSAIQWIFSHSGGSGPEDWINEYADFGRVFIAGDSAGGNISHHMAMRAGKEKLEPRIKGIAVVHPAFWGTDPVDEHDVQDRDMRSGIADVWEKIASPNSVNGTDDPLFNVLGSESDFSEMGCEKVLVAVAGKDVFVRQGLGYAAKLKKSGWGGDVEVVEEEEEGHCFHLLTPDSKNAPKFLKKLVEFIIG
>rna-MERR_LOCUS35541
MLRRITFSSSLRSPSLFFRFFRHLPRSNFSLSSSPTTVGISGSNLRRLSTPITLRCICSHSSSEIASEHPPFVRIYKDGRVERLSGTEIIPASLTPQNGVISKDVVYSPEHNLSVRLFLPQKATELPAGSKIPLLVYIHGGAWIIGSPFESIYHSFLTEVVKSANCLAVSIQYRRAPEDPIPAAYEDSWSAIQWIFSHSDGSGSVDWINKYADFDRVFLAGDSAGANMSHHMAIRAGKEKLKPRIKGTAIVHPAFWGKDPVDELDLQDKEKRSRIAEVWEKLASPNSVDGTDDPWFNVVGSGSDFSEMGCEKVLVAVAGKDVFVRQGLGYAEKLKKSGWEGEVEVVEDEDEDHCFHLLNSDSENAPKFMKKFVDFISG
>rna-MERR_LOCUS35540
MSSHSSSEIASEHPPYARIYKDGRVERMFRTDIIPASLTPQNGVVSKDVVYSPEHNLSVRLFLPQNATEIPAGKKIPLLVYIHGGAWIMGSPFAPIYHNLLSEVVKSANCLAVSIQYRRAPEDPIPAAYEDSWSAIQWIFSHSDGSGGPVDWINKYADFDRVFLAGDSAGANMSHHMAMRAGKEKLEPRIKGIAMVHPAFWGKDPIDELDLQDKEKRRQITELWEKLASPNSVDGTDDPLFNVVGSGSDFSEMGCEKVLVAVAGKDVFVRQGLGYAEKLKKSGWKGEVEVVEDEDEDHCFHLWTPDSENAPKLMKKFVDFISG
>rna-MERR_LOCUS35539
MESDLTIEPLPFIGTLKNGSTVESLRSNEVVPASLDLRNNVVSKDVVYSPELNLSVRLFLPHKKSTELAAGEKLPLLIYFHGGAYIMGSPFSPVSHNYLTEVVKASNCLAVSVQYRLAPEHPIPAAYEDSWSAIQWIFTHSDGFGEDAWINEHADFDRAFLAGDSAGANICHHMAIRAGEEKLNPRFKGVAMVHPGFWGKDPIDEKDVQDDGIRSGIAEVWETLASPNSVDGVNDPWLNVVGSGSDISGLGCETVLLAVAGKDVFGRQGLAYAEKLEKNGWRGDLKVVEEEDEGHCFHLRNPNSENASKLMKAFVEFIIHR
>rna-MERR_LOCUS37135
MESEIAFDMSPSFVVYKNGRLERLTGETIVPPSLNPQNGVISKDVVYSPEKNLSLRIYLPEKVVETDQKLPVLVYFHGGGFIFETAFSPIYHTFLTSAVAAAECLAISVDYRRAPEFPIPVPYEDSWDSLKWVFSYIDGTRPENWINKHADFGKVFLAGDSAGGNIAHHLAIRAEKEKLNPVISGMILIHPYFWGKTPIDELETRDERRRRKIDGSWEVASPNSEKGVDDPLFNVVGSESSDLSGLGCGRVLVMVAGYDIFVRQGFGYAAKLEKSGWGGEVEVMETKREGHAFHLKNPDTDNARQVVKKFAEFLKNKHYLISLL
>rna-MERR_LOCUS37136
MESEIAFDNSPNYRVYKNGRVERLSGETTVPPSLTPQNGVVSKDAVYSPEKNLSVRIFLPAKVVGTDQKLPVLVYFHGGGFVIHTAFSPTYHTFLTTTVAAADCLAISVDYRRAPEFPIPIPYEDSWNSLKWLFRHIDGTGSENWINKHADFAKVFLAGDSAGGNITHHLAMRAKREKLDHLVSGIVLIHPYFWGKNPIDEFETRDVKKRKRVEGCWAIVSPNSEKGVDDPLFNVVGSESSDLSGLGCGRVLVMVAGDDIYARQGLGYAVKLKKSGWEGEVELMEIKDEDHVHHLKNPITDNARQVVKKIAEFLNK
>rna-MERR_LOCUS43661
MDSEIAVDFSPVFKIYKSGRIERLMGEAKVPPSSTPQNGVVSKDVVYSPDDNLSVRIFLPEKAAETGDNKLPLLVYFHGGGFVIETAFSPTYHSFLTAAVSASDCVAVSVDYRRAPEHPIPASYDDSWTALKWVFTHIAGSGSEDWLNKHADFSKVYLAGDSAGANIAHHMAMRAAKEKLSSGLDESSSGISGMILVHPYFWSKTPLDEKETKDVLLRSKIEAFWKMASPNNKDGPDDPWLNVVQSESSDVSGLGCGKVLVMVAEKDALCRQGWGYAAKLEKSGWKGEVELVESEGEDHVFHLMKPDCDKALEAMHKFSGFIKGD
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University