Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Melaleuca alternifolia
Species name
Tea tree (Melaleuca alternifolia) is a species of eudicot in the family Myrtaceae (myrtle family).
Species info
Gene sequence info
Melaleuca_alternifolia.ROMT.fa
Download
>scf7180000028461_mRNA_8
MDSNGNGVMSESEIVQAHAHVWTHTFNFIYSMSLKCAVELGIPDTLHHHGHPMTLPELAAALSVPASKIAFLRRLMAVLAQTGFVSQQKSAAKNDQEPLGVTYSPTPISRAILKDQPGGMSPLVSMILNPIIEEPFHYLGEWLKSESPSLRTPFAMKHGKSLWDYTAQDEGFNRTMNEAMASDGPVIARLMVEKRGRQLFQGLRKVVDVGGGTGGLAREAAEAFPQVEWMVLDLPHVVAGLEGTRNLKFVSGDMFKAVPPADAVLLKWLLHDWTDDECVEILKRCKEAVTSNGKKGKVMIVDIVFGDESDEDEASMGIKLCFDMLMMAVVPGKERNEEEWGKLFREAGFTEYRITPLVNFRSLIEVYP
>scf7180000028461_mRNA_5
MDMVNGEKGSEQLQAQAHIWNHMFHFINSMCLKCAIQLSIPDTIHHHGQPMTLDALVSALQIHPSRVHCVDRLMRILVCSGFFEQKKLAPDGRDAYVLNCVSELLLKDNPLSAAPFAVGMLDPILMEPWHCLSAWFHNLVDPTPFEMAHGLSMWEYAGNEPRLNHLFNEGMASDTRLVASVVVNQCRGVFEGITSLVDVGGGTGTMANAIASTFPHIECILFDLPHVVADLELGKNVKCVAGDMLEAIPPADAVLLKSILHDWSDEDGVKILKRCKEAISKGKGKMKKVIIIDMEVDSRKGDKAMNETQLFFDMLMMTLLSGRERNETEWAKLFVDAGFGDYRITPILGLRSLIEVYPS
>scf7180000028461_mRNA_6
MAMLDPILMNPWHCLSAWFHNLVDLTAFEMAHRMSLWGYAGNEPRLNRLFNEGLASDTRLVASVVINQCRGVFEGITSLVDVGGGTGTMANAIASTFPHIECILFDLPHVVADLELGKNVKCVAGDMLEAIPPGDAVLLKSILHDWSDEDGVKILKRCKEAISKGKGKMKKVIIIDMVVDSRKGDKAMNETQLFFDMLMMTLLSGRERNETEWAKLFVDAGFGDYRITPILGLRSLIEVYPS
>scf7180000028461_mRNA_12
MSEREIFRAHAHVWSHAFNFISSMSLKCAIELGIPDVLYRCSHPMTLPELATALSVPASKAAFLSRLVAVLVHTGFLSCQKPASETNEISGDKAEELGYEYSLTPASCAIVKGQSLDLSPIVLLTLDPIFVDPFHCLSEWLKCDSKTGSSSSRTPLHMKHGKSMWEIKVQDEKFNRCMNEAMASDGPVMARMMMEKCGRRLFEGLRTAVDVGGGTGGLARELAEAFPEMEWLVLDLPRVVADLEGTRNLKYVGGDMFAAIPPADAVLLKWVLHDWSDEESVKILKRCKEAITSNDGTGKAIIVEAVIGDGPEEGETMKLLYDMIMMVGTTGKERDGKEWAKLFREAGFSDHKITPLEGFRSLIEVYP
>scf7180000028461_mRNA_11
MVLDLPHVVAGLEGTRNLKFVSGDMFEAVPPADAVLLKWILHDWTDDECVKILKRCKEAVTSNGKKGKVMIVDIVFGDESDEDEASMGIKLCFDMLMMTVVPGKERNKEEWGKLFREAGFTEYRITPLVDFRSLIEVYP
>scf7180000028461_mRNA_18
MVHGGPSWELMKGNPEVSDLFCGAMEHDSRLMTKVVLDTCGGVFKGLSSVVDVGGGSGTMGKAIAEAFPHLECTVLDLPHVVDGLVGSERLKFVGGDMFVEIPQADAILFKWILHDWSDEKCIKILKRSKEAVSGAVEVGKVIIIDMVVENRSGDHRSSETQLFFDMAMMVSVNAKERDEKEWKQLFVDAGFSGYKIISRLGLRSLIEVYP
>scf7180000028461_mRNA_23
MDLANRDGNVTASELLRAQDYIWNHMLSSVNSLCLKCVIQLGIPELIHDHGRPMTLLELVSALHIHPTKAHCIQRIMRILVHSGFFELRHLKEVDHQTGYALTVASRLLLKHNPSSLVPFVLVALHPFTMAPWQYLSTWLRDGDQDLTRSTLEMAHGGPAWELMRGNPELDNLFYEMMENDSRLMAKVVLDTCGGVFEGLSSVVDVGGGTGIMGKAITDAFPHLECTVFDLPHLVNGLVGSERLKFVGGDMFVEIPPANALLLKLILHDWNDEKCIEILKRSKEALSGGGKAGKVIVIDMVVGNQQEDHKSTETQLFFDVAMMVGFNGKERSEKEWEKLFVDAGFSSYKIISRLGLRSLIEIYP
>scf7180000028461_mRNA_21
MDLANRDGNVTASELLQSQDYIWNHMLSSVNSLCLKCVIQLGIPELIHDHGRPMTLLELVSALHIHPTKAHCIQRIMRILVHPGFFELRDLKEVDSQTGHALTVASRLLLKHNPSSLVPFVFVALHPFAMAPWQYLSTWLRDGEDLTRSTLEMAHGGPAWEMMRGNPELDNLFCVMMENDLRLMAKVVLETCGGVFEGLSLVVDLGGGTGIMGKAITDAFPHFECTVFDLPHLANGLVGSERLKFVGGDMFVEIPPANALLLKVWLKSAYGMKNWEFFLRLNFRASNFDSLGMLYDVKFTGDY
>scf7180000029144_mRNA_106
MAHGVPSWEFARRNPEVNGLFNEAMARDSSLMAKAVVDTCGRVFEGLSSVVDVGGGTGTMGKVITEAFPHLECTVLDQPHVVDGLVGSDKLKFVGGDMFVEIPPADAIILKWILHDWSDEKCIEILKRSKEAVSGQGKARKAIMIDMVVGNQTEDHTSTESQLFFDMLMMVTFNGNERNEKEWEKLFVDVGFSNYKIVSRLGLRSLVEIYPSLCFCLFDLLV
>scf7180000029166_mRNA_27
MAHGVPSWEFARRNPEVNGLFNEAMARDSSLMAKAVVDTCGRVFEGLSSVVDVGGGTGTMGKVITEAFPHLECTVLDQPHVVDGLVGSDKLKFVGGDMFVEIPPADAIILKWILHDWSDEKCIEILKRSKEAVSGQGKARKAIMIDMVVGNQTEDHTSTESQLFFDMLMMVTFNGNERNEKEWEKLFVDVGFSNYKIVSRLGLRSLVEIYPSLCFCLFDLLV
>scf7180000036300_mRNA_1
MAMLDPILMNPWHCLSAWFHNLVDLTAFEMAHRMSLWGYAGNEPRLNRLFNEGLASDTRLVASVVINQCRGVFEGITSLVDVGGGTGTMANAIASTFPHIECILFDLPHVVADLELGKNVKCVAGDMLEAIPPGDAVLLKSILHDWSDEDGVKILKRCKEAISKGKGKMKKVIIIDMVVDSRKGDKAMNETQLFFDMLMMTLLSGRERNETEWAKLFVDAGFGDYRITPILGLRSLIEVYPS
>scf7180000036300_mRNA_2
MDMVNGEKGSEQLQAQAHIWNHMFHFINSMCLKCAIQLSIPDTIHHHGQPMTLDALVSALQIHPSRVHCVDRLMRILVCSGFFEQKKLAPDGRDAYVLNCVSELLLKDNPLSAAPFAVGMLDPILMEPWHCLSAWFHNLVDPTPFEMAHGLSMWEYAGNEPRLNHLFNEGMASDTRLVASVVVNQCRGVFEGITSLVDVGGGTGTMANAIASTFPHIECILFDLPHVVADLELGKNVKCVAGDMLEAIPPADAVLLKSILHDWSDEDGVKILKRCKEAISKGKGKMKKVIIIDMEVDSRKGDKAMNETQLFFDMLMMTLLSGRERNETEWAKLFVDAGFGDYRITPILGLRSLIEVYPS
>scf7180000037782_mRNA_165
MDLANEDGDAAASELLQAQAHIWNHVYSFIKSMCLKCAIQLGIPDLIHNHGRPMTSVELVSVLNVQPNKANCIHRLMRILVHSGFFELRDLEQADYETGYVLTRASRLLVTSNTLSVAPFALLMLEPFSVEPWQHLSSWLGDGEDVAPSAFEMAHGVPAWEFSRRNPKVSSLFDEAMASDSRLIAKVVADKCGGVFEGLSSVVDVGGGSGTMGKTITDAFPHLECTFVGGDMFVAIPPADAVFLKWILHDWSDEKCIEILKRCKEAVSGRGKAAKVIMIDMVVGNQTEDHISTETQLFFDLGMMMTFNGKERDEKEWEKLFGGAGFTGYKIVSRLGLRSLIDIYP
>scf7180000037782_mRNA_172
MNFSDKGGDATASELLRAQAHIWNHTLSFINSMCLKGAIELGIPDLIHNHGRPMTLLELVSALHIQLTKAHCIHRLMRILVHSVFFELQKLEEGDRQIGYALTCVSRLLTKHNPSSLSPFALFILQPFCMGQWQYLSAWLKDGEDVHPSAFEMAHGVPSWEFARRNPEINGLFNEAMARDSSLIAKVVVDTCGRVFEGLSSVVDGGGGTGTMGKAMTEAFPHLECTVLDQPHVVDGLVGSDRLKFVGGDMFVEIPPADAIILKWILHDWSDEKCIEILKRSKEAMSGQGKAGKVIMIDMVVGNQTEDHTSTESQLFFDMLMMVTFNGNERNEKEWEKLFVDAGFSNYKIVSRLGLRSLVEIYP
MDSNGNGVMSESEIVQAHAHVWTHTFNFIYSMSLKCAVELGIPDTLHHHGHPMTLPELAAALSVPASKIAFLRRLMAVLAQTGFVSQQKSAAKNDQEPLGVTYSPTPISRAILKDQPGGMSPLVSMILNPIIEEPFHYLGEWLKSESPSLRTPFAMKHGKSLWDYTAQDEGFNRTMNEAMASDGPVIARLMVEKRGRQLFQGLRKVVDVGGGTGGLAREAAEAFPQVEWMVLDLPHVVAGLEGTRNLKFVSGDMFKAVPPADAVLLKWLLHDWTDDECVEILKRCKEAVTSNGKKGKVMIVDIVFGDESDEDEASMGIKLCFDMLMMAVVPGKERNEEEWGKLFREAGFTEYRITPLVNFRSLIEVYP
>scf7180000028461_mRNA_5
MDMVNGEKGSEQLQAQAHIWNHMFHFINSMCLKCAIQLSIPDTIHHHGQPMTLDALVSALQIHPSRVHCVDRLMRILVCSGFFEQKKLAPDGRDAYVLNCVSELLLKDNPLSAAPFAVGMLDPILMEPWHCLSAWFHNLVDPTPFEMAHGLSMWEYAGNEPRLNHLFNEGMASDTRLVASVVVNQCRGVFEGITSLVDVGGGTGTMANAIASTFPHIECILFDLPHVVADLELGKNVKCVAGDMLEAIPPADAVLLKSILHDWSDEDGVKILKRCKEAISKGKGKMKKVIIIDMEVDSRKGDKAMNETQLFFDMLMMTLLSGRERNETEWAKLFVDAGFGDYRITPILGLRSLIEVYPS
>scf7180000028461_mRNA_6
MAMLDPILMNPWHCLSAWFHNLVDLTAFEMAHRMSLWGYAGNEPRLNRLFNEGLASDTRLVASVVINQCRGVFEGITSLVDVGGGTGTMANAIASTFPHIECILFDLPHVVADLELGKNVKCVAGDMLEAIPPGDAVLLKSILHDWSDEDGVKILKRCKEAISKGKGKMKKVIIIDMVVDSRKGDKAMNETQLFFDMLMMTLLSGRERNETEWAKLFVDAGFGDYRITPILGLRSLIEVYPS
>scf7180000028461_mRNA_12
MSEREIFRAHAHVWSHAFNFISSMSLKCAIELGIPDVLYRCSHPMTLPELATALSVPASKAAFLSRLVAVLVHTGFLSCQKPASETNEISGDKAEELGYEYSLTPASCAIVKGQSLDLSPIVLLTLDPIFVDPFHCLSEWLKCDSKTGSSSSRTPLHMKHGKSMWEIKVQDEKFNRCMNEAMASDGPVMARMMMEKCGRRLFEGLRTAVDVGGGTGGLARELAEAFPEMEWLVLDLPRVVADLEGTRNLKYVGGDMFAAIPPADAVLLKWVLHDWSDEESVKILKRCKEAITSNDGTGKAIIVEAVIGDGPEEGETMKLLYDMIMMVGTTGKERDGKEWAKLFREAGFSDHKITPLEGFRSLIEVYP
>scf7180000028461_mRNA_11
MVLDLPHVVAGLEGTRNLKFVSGDMFEAVPPADAVLLKWILHDWTDDECVKILKRCKEAVTSNGKKGKVMIVDIVFGDESDEDEASMGIKLCFDMLMMTVVPGKERNKEEWGKLFREAGFTEYRITPLVDFRSLIEVYP
>scf7180000028461_mRNA_18
MVHGGPSWELMKGNPEVSDLFCGAMEHDSRLMTKVVLDTCGGVFKGLSSVVDVGGGSGTMGKAIAEAFPHLECTVLDLPHVVDGLVGSERLKFVGGDMFVEIPQADAILFKWILHDWSDEKCIKILKRSKEAVSGAVEVGKVIIIDMVVENRSGDHRSSETQLFFDMAMMVSVNAKERDEKEWKQLFVDAGFSGYKIISRLGLRSLIEVYP
>scf7180000028461_mRNA_23
MDLANRDGNVTASELLRAQDYIWNHMLSSVNSLCLKCVIQLGIPELIHDHGRPMTLLELVSALHIHPTKAHCIQRIMRILVHSGFFELRHLKEVDHQTGYALTVASRLLLKHNPSSLVPFVLVALHPFTMAPWQYLSTWLRDGDQDLTRSTLEMAHGGPAWELMRGNPELDNLFYEMMENDSRLMAKVVLDTCGGVFEGLSSVVDVGGGTGIMGKAITDAFPHLECTVFDLPHLVNGLVGSERLKFVGGDMFVEIPPANALLLKLILHDWNDEKCIEILKRSKEALSGGGKAGKVIVIDMVVGNQQEDHKSTETQLFFDVAMMVGFNGKERSEKEWEKLFVDAGFSSYKIISRLGLRSLIEIYP
>scf7180000028461_mRNA_21
MDLANRDGNVTASELLQSQDYIWNHMLSSVNSLCLKCVIQLGIPELIHDHGRPMTLLELVSALHIHPTKAHCIQRIMRILVHPGFFELRDLKEVDSQTGHALTVASRLLLKHNPSSLVPFVFVALHPFAMAPWQYLSTWLRDGEDLTRSTLEMAHGGPAWEMMRGNPELDNLFCVMMENDLRLMAKVVLETCGGVFEGLSLVVDLGGGTGIMGKAITDAFPHFECTVFDLPHLANGLVGSERLKFVGGDMFVEIPPANALLLKVWLKSAYGMKNWEFFLRLNFRASNFDSLGMLYDVKFTGDY
>scf7180000029144_mRNA_106
MAHGVPSWEFARRNPEVNGLFNEAMARDSSLMAKAVVDTCGRVFEGLSSVVDVGGGTGTMGKVITEAFPHLECTVLDQPHVVDGLVGSDKLKFVGGDMFVEIPPADAIILKWILHDWSDEKCIEILKRSKEAVSGQGKARKAIMIDMVVGNQTEDHTSTESQLFFDMLMMVTFNGNERNEKEWEKLFVDVGFSNYKIVSRLGLRSLVEIYPSLCFCLFDLLV
>scf7180000029166_mRNA_27
MAHGVPSWEFARRNPEVNGLFNEAMARDSSLMAKAVVDTCGRVFEGLSSVVDVGGGTGTMGKVITEAFPHLECTVLDQPHVVDGLVGSDKLKFVGGDMFVEIPPADAIILKWILHDWSDEKCIEILKRSKEAVSGQGKARKAIMIDMVVGNQTEDHTSTESQLFFDMLMMVTFNGNERNEKEWEKLFVDVGFSNYKIVSRLGLRSLVEIYPSLCFCLFDLLV
>scf7180000036300_mRNA_1
MAMLDPILMNPWHCLSAWFHNLVDLTAFEMAHRMSLWGYAGNEPRLNRLFNEGLASDTRLVASVVINQCRGVFEGITSLVDVGGGTGTMANAIASTFPHIECILFDLPHVVADLELGKNVKCVAGDMLEAIPPGDAVLLKSILHDWSDEDGVKILKRCKEAISKGKGKMKKVIIIDMVVDSRKGDKAMNETQLFFDMLMMTLLSGRERNETEWAKLFVDAGFGDYRITPILGLRSLIEVYPS
>scf7180000036300_mRNA_2
MDMVNGEKGSEQLQAQAHIWNHMFHFINSMCLKCAIQLSIPDTIHHHGQPMTLDALVSALQIHPSRVHCVDRLMRILVCSGFFEQKKLAPDGRDAYVLNCVSELLLKDNPLSAAPFAVGMLDPILMEPWHCLSAWFHNLVDPTPFEMAHGLSMWEYAGNEPRLNHLFNEGMASDTRLVASVVVNQCRGVFEGITSLVDVGGGTGTMANAIASTFPHIECILFDLPHVVADLELGKNVKCVAGDMLEAIPPADAVLLKSILHDWSDEDGVKILKRCKEAISKGKGKMKKVIIIDMEVDSRKGDKAMNETQLFFDMLMMTLLSGRERNETEWAKLFVDAGFGDYRITPILGLRSLIEVYPS
>scf7180000037782_mRNA_165
MDLANEDGDAAASELLQAQAHIWNHVYSFIKSMCLKCAIQLGIPDLIHNHGRPMTSVELVSVLNVQPNKANCIHRLMRILVHSGFFELRDLEQADYETGYVLTRASRLLVTSNTLSVAPFALLMLEPFSVEPWQHLSSWLGDGEDVAPSAFEMAHGVPAWEFSRRNPKVSSLFDEAMASDSRLIAKVVADKCGGVFEGLSSVVDVGGGSGTMGKTITDAFPHLECTFVGGDMFVAIPPADAVFLKWILHDWSDEKCIEILKRCKEAVSGRGKAAKVIMIDMVVGNQTEDHISTETQLFFDLGMMMTFNGKERDEKEWEKLFGGAGFTGYKIVSRLGLRSLIDIYP
>scf7180000037782_mRNA_172
MNFSDKGGDATASELLRAQAHIWNHTLSFINSMCLKGAIELGIPDLIHNHGRPMTLLELVSALHIQLTKAHCIHRLMRILVHSVFFELQKLEEGDRQIGYALTCVSRLLTKHNPSSLSPFALFILQPFCMGQWQYLSAWLKDGEDVHPSAFEMAHGVPSWEFARRNPEINGLFNEAMARDSSLIAKVVVDTCGRVFEGLSSVVDGGGGTGTMGKAMTEAFPHLECTVLDQPHVVDGLVGSDRLKFVGGDMFVEIPPADAIILKWILHDWSDEKCIEILKRSKEAMSGQGKAGKVIMIDMVVGNQTEDHTSTESQLFFDMLMMVTFNGNERNEKEWEKLFVDAGFSNYKIVSRLGLRSLVEIYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University