Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Melaleuca alternifolia
Species name
Tea tree (Melaleuca alternifolia) is a species of eudicot in the family Myrtaceae (myrtle family).
Species info
Gene sequence info
Melaleuca_alternifolia.4CL.fa
Download
>scf7180000028398_mRNA_234
MISVAPAPDTSPQNPSELPPAHDQEKQQTPVACTVFRSKLPDIPISNHLSLHAYCFEHVSRFSHRPCLISDSTGKNFSFSDTLLLSRKVAAGLHNLGIRKGDVVMTLLQNCPEFAFSFMGASMIGAVTTTANPFYTPSEIFKQFGTSRAKLIITQSLYVDKLRDQRDGVGPTLGKDFTVITVDDPPEGCIHFSVLSEANEEEAPEVEIHPDDPVALPFSSGTTGLPKGVILTHRSLITSIAQQVDGENPNLHLSAEDVVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMHKFEIGTLLQLIERHRVSVAAVVPPLVLALAKNPLVEKFDLSSIRMVLSGAAPLGKELELALQSRLPGAILGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGSSLGYNQPGEICIRGQQIMKGYLNDPEATSITIDADGWLHTGDIGYVDDDDEIFIVDRVKEIIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDEVAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHKVHFVHAIPKSPSGKILRKDLRAKLTTAASIS
>scf7180000028710_mRNA_147
MANSNSFDRETSTYRSPRPPLHFPSEPNLTLTSHLFRSYSSSSLSCSPQSLALIDADSGESLTFHQLENRVSTLSHVLLRKLGLGKSDVVLLFCPNSIHFPVCFLSIVSLGAIATTCNPMYTLSELSKQFNDCEPKLVITVPELYDKVRGFELPTMLLGYLQPGKSASSKMWSYFDLVKSAEPISDLPPNCVAQDDVAALLYSSGTTGTSKGVILTHRNFISASVMATADQERYKEGKNVFLAFLPMFHVMGLSVIVYAQLTRGNTMVTLRKFELEKVLWCVERYRVSYLFVAPPVMVMLAKWRGGKKYDLSSLRLIGSGAAPLSKEVMEDCAQNIPHVDIIQGYGMTETCGVISLGNHREEPKLSGSTGTLVSGVESKIVSVETSMPLPPNQLGEIWVRGPNMMKGYLNNLDATKQTIDDEGWVHTGDLGYFNEEGQLFVVDRLKDLIKCHGFQVAPAELEGLLLSHPEILSAVVIPFPDAKAGEVPIAYVVRSHNSSLTEARVQEFIVNQVAPFKRLRKVTFINSVPKTAAGKILRRELKEKAQSKI
>scf7180000036588_mRNA_250
MEAKPLDQPREFIFRSKLPDIYIPDHLSLHGYCFEHISEFADRPCIIDGATGRTYTYCEVEVTARRVAAGLDGLGVGQGDVIMLLLHNSPEFIFAFVGASYRGAISTTANPFYTPAEIAKQASASRAKVVVTQAAYAGKVKQFAEENGVKIVCIDTAPEGCLHFSELIQADENAAPAVEINPDDVLALPYSSGTTGLPKGVMLTHRGQVTSVAQQVDGDNPNLYFHKEDVILCVLPLFHIYCLNSVMLCALRVGAAILIMQKFEIVSLMELVQRYRVTILPIVPPIVLEIAKSAEVDRYDLSSIRTVMSGAAPMGKELEDNVRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGRQIMKGYLNDPEATARTLDKEGWLHTGDVGLIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPDISDAAVVPMKDEAASEIPVAFVVKSNGSKITEDEIKQYISKQVIYYKRIKRVFFTDAIPKAPSGKILRKDLRAKLASGVYN
>scf7180000036596_mRNA_396
MGTYIESAVHDEEHIFRSQYPVVPVPNCTLPDFVLHGAELYADNVAFVDSVSGRSYTYAEVVRDTRRFAKALRSLGLRKGRVVIVVLPNVAEYGIVALGIMAAGAVFSGANPTMHASEIKKQVEAADAKLIVTDGPNYEKVKAFGLPVIVLGGEQIETATNWDDLLKAGDRASIGSVEEDVDPNDLCALPFSSGTTGISKGVMLTHRNLVANLCSTLFSVPPEMVGCVTILGLIPFFHIYGITGICCASLKNKGKVVVMNRFDLRSFLNALIAHEVNFAPIVPPIILSLVKDPIVDEFDLGKLKLSAIMTAAAPLAPEILFAFENKFPGVQVQEAYGLTEHSCITLTHGDPRKDHSIAKKNSVGFVLPNLEIKFIDPENGQSLPKNTPGELCVRSQCVMRGYYKNEEETSRTIDKEGWLHTGDIGYIDDDGDVFIVDRIKELIKFKGFQVAPAELEAILLTHSSIVDAAVVPLPDEEAGEIPAACVVLNPGAKESEDDIINYVASNVAGYKRVRAVQFVDSIPKSPSGKILRRLLRDKMMQHMQMEMKTRAAIL
>scf7180000039061_mRNA_191
MEKSGYGRDGIYRSLRPSLVLPRKPDLSMVSFLFRNSSSYADKPALVDADTGEILTFSQFESTVIKVAHGLLNLGLKKNDVVLIFSPNSIQFPLCFFGVTSIGAIATTANPLYTSGELFKQVKDSNPKLIVTVPALWEKVKDLNLPAVILGDSKSLSGQISSKSRILSFHDLVNLGNGASSFPQVNVKQSDVAALLYSSGTTGTSKGVILTHGNFIAASLMVTMDQEVAGEMHHVFLCVLPMFHVFGLAVITYSQLQKGNALVSLGRFEFDSVLRVVQKYRITHLWVVPPIILALAKQSVVRKYDLSSLKHIGSGAAPLGKDVMEDCAKNFPHAAVAQGYGMTETCGIVSVENTSFGVRHTGSTGQLVSGVEAQIISVDTLKPLPPNELGEIWVRGPNMMKGYYNNPQATKSTLDKKGWVHTGDLGYFDEEGRLYVVDRIKELIKYKGYQIAPAELEGLLLSHSEILDAVVIPFPDAEAGEVPIAYVVRSPTSSLTEEEVQKFIANQVAPFKRLRRVTFINSVPKSASGKILRRELIAKVRAKI
MISVAPAPDTSPQNPSELPPAHDQEKQQTPVACTVFRSKLPDIPISNHLSLHAYCFEHVSRFSHRPCLISDSTGKNFSFSDTLLLSRKVAAGLHNLGIRKGDVVMTLLQNCPEFAFSFMGASMIGAVTTTANPFYTPSEIFKQFGTSRAKLIITQSLYVDKLRDQRDGVGPTLGKDFTVITVDDPPEGCIHFSVLSEANEEEAPEVEIHPDDPVALPFSSGTTGLPKGVILTHRSLITSIAQQVDGENPNLHLSAEDVVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMHKFEIGTLLQLIERHRVSVAAVVPPLVLALAKNPLVEKFDLSSIRMVLSGAAPLGKELELALQSRLPGAILGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGSSLGYNQPGEICIRGQQIMKGYLNDPEATSITIDADGWLHTGDIGYVDDDDEIFIVDRVKEIIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDEVAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHKVHFVHAIPKSPSGKILRKDLRAKLTTAASIS
>scf7180000028710_mRNA_147
MANSNSFDRETSTYRSPRPPLHFPSEPNLTLTSHLFRSYSSSSLSCSPQSLALIDADSGESLTFHQLENRVSTLSHVLLRKLGLGKSDVVLLFCPNSIHFPVCFLSIVSLGAIATTCNPMYTLSELSKQFNDCEPKLVITVPELYDKVRGFELPTMLLGYLQPGKSASSKMWSYFDLVKSAEPISDLPPNCVAQDDVAALLYSSGTTGTSKGVILTHRNFISASVMATADQERYKEGKNVFLAFLPMFHVMGLSVIVYAQLTRGNTMVTLRKFELEKVLWCVERYRVSYLFVAPPVMVMLAKWRGGKKYDLSSLRLIGSGAAPLSKEVMEDCAQNIPHVDIIQGYGMTETCGVISLGNHREEPKLSGSTGTLVSGVESKIVSVETSMPLPPNQLGEIWVRGPNMMKGYLNNLDATKQTIDDEGWVHTGDLGYFNEEGQLFVVDRLKDLIKCHGFQVAPAELEGLLLSHPEILSAVVIPFPDAKAGEVPIAYVVRSHNSSLTEARVQEFIVNQVAPFKRLRKVTFINSVPKTAAGKILRRELKEKAQSKI
>scf7180000036588_mRNA_250
MEAKPLDQPREFIFRSKLPDIYIPDHLSLHGYCFEHISEFADRPCIIDGATGRTYTYCEVEVTARRVAAGLDGLGVGQGDVIMLLLHNSPEFIFAFVGASYRGAISTTANPFYTPAEIAKQASASRAKVVVTQAAYAGKVKQFAEENGVKIVCIDTAPEGCLHFSELIQADENAAPAVEINPDDVLALPYSSGTTGLPKGVMLTHRGQVTSVAQQVDGDNPNLYFHKEDVILCVLPLFHIYCLNSVMLCALRVGAAILIMQKFEIVSLMELVQRYRVTILPIVPPIVLEIAKSAEVDRYDLSSIRTVMSGAAPMGKELEDNVRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGRQIMKGYLNDPEATARTLDKEGWLHTGDVGLIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPDISDAAVVPMKDEAASEIPVAFVVKSNGSKITEDEIKQYISKQVIYYKRIKRVFFTDAIPKAPSGKILRKDLRAKLASGVYN
>scf7180000036596_mRNA_396
MGTYIESAVHDEEHIFRSQYPVVPVPNCTLPDFVLHGAELYADNVAFVDSVSGRSYTYAEVVRDTRRFAKALRSLGLRKGRVVIVVLPNVAEYGIVALGIMAAGAVFSGANPTMHASEIKKQVEAADAKLIVTDGPNYEKVKAFGLPVIVLGGEQIETATNWDDLLKAGDRASIGSVEEDVDPNDLCALPFSSGTTGISKGVMLTHRNLVANLCSTLFSVPPEMVGCVTILGLIPFFHIYGITGICCASLKNKGKVVVMNRFDLRSFLNALIAHEVNFAPIVPPIILSLVKDPIVDEFDLGKLKLSAIMTAAAPLAPEILFAFENKFPGVQVQEAYGLTEHSCITLTHGDPRKDHSIAKKNSVGFVLPNLEIKFIDPENGQSLPKNTPGELCVRSQCVMRGYYKNEEETSRTIDKEGWLHTGDIGYIDDDGDVFIVDRIKELIKFKGFQVAPAELEAILLTHSSIVDAAVVPLPDEEAGEIPAACVVLNPGAKESEDDIINYVASNVAGYKRVRAVQFVDSIPKSPSGKILRRLLRDKMMQHMQMEMKTRAAIL
>scf7180000039061_mRNA_191
MEKSGYGRDGIYRSLRPSLVLPRKPDLSMVSFLFRNSSSYADKPALVDADTGEILTFSQFESTVIKVAHGLLNLGLKKNDVVLIFSPNSIQFPLCFFGVTSIGAIATTANPLYTSGELFKQVKDSNPKLIVTVPALWEKVKDLNLPAVILGDSKSLSGQISSKSRILSFHDLVNLGNGASSFPQVNVKQSDVAALLYSSGTTGTSKGVILTHGNFIAASLMVTMDQEVAGEMHHVFLCVLPMFHVFGLAVITYSQLQKGNALVSLGRFEFDSVLRVVQKYRITHLWVVPPIILALAKQSVVRKYDLSSLKHIGSGAAPLGKDVMEDCAKNFPHAAVAQGYGMTETCGIVSVENTSFGVRHTGSTGQLVSGVEAQIISVDTLKPLPPNELGEIWVRGPNMMKGYYNNPQATKSTLDKKGWVHTGDLGYFDEEGRLYVVDRIKELIKYKGYQIAPAELEGLLLSHSEILDAVVIPFPDAEAGEVPIAYVVRSPTSSLTEEEVQKFIANQVAPFKRLRRVTFINSVPKSASGKILRRELIAKVRAKI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University