Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Megadenia pygmaea
Species name
Megadenia pygmaea is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Megadenia_pygmaea.CHS.fa
Download
>Mpyg04175.t1
MVCGSGGLHALFVSKSVVRYPPPVIRNQGSKSKLARSMARAVNSNPWSLELESSLSSLYHPSGSLSTTAVLQTLRLIKVPADALRFFDWVSNKGFSHRDHSFFLMLEFLGRARNLNAARNFLFSIEKRSNGCVKLHDRYFNSLIRSYGNAGLFQESLKLFQTMKTMGISPSVLTFNSLLSVLLKRGKTGLAHDMFDEMRRTYGVTPDSYTFNILIRGFCKNSMVDEAFRIFKEMESYKCNPDLVTYNTIMDGLCRAGKVNIAHNVLNGMTRKATDLHPNIVSYTTLVRGYCMKQEIDEALLLFHQMLTRGLKPNAVTYNTLIKGLSEAQRYDEIKEILNGWDTCTTFAPDSCTFNILIKAHCDAEHLDAATKVFKEMVNMKLHPDSASYSVLIRTLCLRNEFDRAEALFNELFEKEVLLGKDGCKPLAAAYNPMFEYLCANGKTKQAEKVFRQLMKRGAQDPPSYRTLIRGHCREGKFKAAYELLVLMLRREFVPDLETYELLIDGLLKIGEAVLAHDTLQRMLRSSYLPVATTFHSVLAELVKRKFANESFGFLRLMLEKRIRQNIDLSTHAVRLLFDSAQKENAFLIVRLLYDNGYLVKMEELLDFLCENRKLLDAHRLVLLFLEKGQMLDIGTYNTVIEGLCKHKRHSEAFSLYNELGNHHQLSCHMVLRNALEAAGKWEELQSNRASGFLMSNSVMNGVEKLSSIHTRRVANPGKATVLALGKAFPSQVVPQENLVEGFLRDTKCDDAFIKEKLEHLCKTTTVKTRYTVLSREILDKYPELTTEGSPTIKQRLEIANEAVVEMALEASLGCIKEWGRPVEDITHVVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIVGADPRESEAPFMELHYAVQQFLPGTQNVIDGRLTEEGINFKLGRDLPQKIEENIEEFCKKLMRKVGDESMEFNDMFWAVHPGGPAILNRLETKLKLERGKLESSRRALVDYGNVSSNTILYVMEYMRDELKKKGDAAQEWGLGLAFGPGITFEGLLLRSLASP
>Mpyg07601.t1
MGSIDAAELGSGKKSNPGKATILALGKAFPHQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILLKYPELAIEGRSTVKQRLDICNGAVTEMAVEASRACIKNWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAVIIGSDPDPICEKPLFELHTAIQNFLPGTEKTIDGRLTEQGINFTLARELPQIIEDNVENFCKKLIGKAGLAHKDYNQMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESKKMRNMNEEEENEWGLILAFGPGVTFEGIVARNLDV
>Mpyg11847.t1
MVMGASSSLDEIRKAQRADGPAGILGIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPNMCAYMAPSLDSRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKILGLRPSVKRFMMYQQGCHAGGTVLRLAKDLAENNSGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWVAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAEDGAATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>Mpyg14766.t1
MAVALSAYPLLGLRRSRRGVSAFRTICSIFANPAQRAKRNLVELIADQDRGLRTQKDASKRDAIVNAIESMAAIGGSSTTTGDSLSATWRLLWTTEKEQLFIIEKAGLFGTRAGDVLQVIDVQKRMLNNVITFPPDGVFFVRSDIHIASPQRRGAQRKELGDPTATIWAGLMLASGRVEKQKEIGTSTRRVANPGKATVLALGKAFPSNVVSQENLVEDYLREIKCDDLSIKDKLQHLCKTTTVKTRYTVMSPETLQKYPELATEGSPTIKQRLEIANEAVVQMAYEASLVCIKEWGRAMEDITHLVYVSSSEFRLPGGDLHLSAQLGLSNGVQRVMLYFLGCDGGVSGLHVAKDIAENNRGSRVLLTTSETMVLVFRPPNKARPYDLVGAALFGDGAAALIIGADPTESESPFMELHCSLQQFLPGTQGVIDGRLSEEGISFKLGRDLPQKIEDNVEEFCKKLVAKAGSGSLELNDLFWAVHPGGPAILNGLETKLKLKPEKLECSRRALMDYGNVSSNTIFYIMDNVRDELERKGRGGEEWGLMRRNHFRRLSHEEPLNRRL
MVCGSGGLHALFVSKSVVRYPPPVIRNQGSKSKLARSMARAVNSNPWSLELESSLSSLYHPSGSLSTTAVLQTLRLIKVPADALRFFDWVSNKGFSHRDHSFFLMLEFLGRARNLNAARNFLFSIEKRSNGCVKLHDRYFNSLIRSYGNAGLFQESLKLFQTMKTMGISPSVLTFNSLLSVLLKRGKTGLAHDMFDEMRRTYGVTPDSYTFNILIRGFCKNSMVDEAFRIFKEMESYKCNPDLVTYNTIMDGLCRAGKVNIAHNVLNGMTRKATDLHPNIVSYTTLVRGYCMKQEIDEALLLFHQMLTRGLKPNAVTYNTLIKGLSEAQRYDEIKEILNGWDTCTTFAPDSCTFNILIKAHCDAEHLDAATKVFKEMVNMKLHPDSASYSVLIRTLCLRNEFDRAEALFNELFEKEVLLGKDGCKPLAAAYNPMFEYLCANGKTKQAEKVFRQLMKRGAQDPPSYRTLIRGHCREGKFKAAYELLVLMLRREFVPDLETYELLIDGLLKIGEAVLAHDTLQRMLRSSYLPVATTFHSVLAELVKRKFANESFGFLRLMLEKRIRQNIDLSTHAVRLLFDSAQKENAFLIVRLLYDNGYLVKMEELLDFLCENRKLLDAHRLVLLFLEKGQMLDIGTYNTVIEGLCKHKRHSEAFSLYNELGNHHQLSCHMVLRNALEAAGKWEELQSNRASGFLMSNSVMNGVEKLSSIHTRRVANPGKATVLALGKAFPSQVVPQENLVEGFLRDTKCDDAFIKEKLEHLCKTTTVKTRYTVLSREILDKYPELTTEGSPTIKQRLEIANEAVVEMALEASLGCIKEWGRPVEDITHVVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIVGADPRESEAPFMELHYAVQQFLPGTQNVIDGRLTEEGINFKLGRDLPQKIEENIEEFCKKLMRKVGDESMEFNDMFWAVHPGGPAILNRLETKLKLERGKLESSRRALVDYGNVSSNTILYVMEYMRDELKKKGDAAQEWGLGLAFGPGITFEGLLLRSLASP
>Mpyg07601.t1
MGSIDAAELGSGKKSNPGKATILALGKAFPHQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILLKYPELAIEGRSTVKQRLDICNGAVTEMAVEASRACIKNWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAVIIGSDPDPICEKPLFELHTAIQNFLPGTEKTIDGRLTEQGINFTLARELPQIIEDNVENFCKKLIGKAGLAHKDYNQMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESKKMRNMNEEEENEWGLILAFGPGVTFEGIVARNLDV
>Mpyg11847.t1
MVMGASSSLDEIRKAQRADGPAGILGIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPNMCAYMAPSLDSRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKILGLRPSVKRFMMYQQGCHAGGTVLRLAKDLAENNSGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWVAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAEDGAATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>Mpyg14766.t1
MAVALSAYPLLGLRRSRRGVSAFRTICSIFANPAQRAKRNLVELIADQDRGLRTQKDASKRDAIVNAIESMAAIGGSSTTTGDSLSATWRLLWTTEKEQLFIIEKAGLFGTRAGDVLQVIDVQKRMLNNVITFPPDGVFFVRSDIHIASPQRRGAQRKELGDPTATIWAGLMLASGRVEKQKEIGTSTRRVANPGKATVLALGKAFPSNVVSQENLVEDYLREIKCDDLSIKDKLQHLCKTTTVKTRYTVMSPETLQKYPELATEGSPTIKQRLEIANEAVVQMAYEASLVCIKEWGRAMEDITHLVYVSSSEFRLPGGDLHLSAQLGLSNGVQRVMLYFLGCDGGVSGLHVAKDIAENNRGSRVLLTTSETMVLVFRPPNKARPYDLVGAALFGDGAAALIIGADPTESESPFMELHCSLQQFLPGTQGVIDGRLSEEGISFKLGRDLPQKIEDNVEEFCKKLVAKAGSGSLELNDLFWAVHPGGPAILNGLETKLKLKPEKLECSRRALMDYGNVSSNTIFYIMDNVRDELERKGRGGEEWGLMRRNHFRRLSHEEPLNRRL
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