Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Megadenia pygmaea
Species name
Megadenia pygmaea is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Megadenia_pygmaea.4CL.fa
Download
>Mpyg00360.t1
MAPQQEVMEKQSNNSDVIFRSKLPDIYIPNHLPLHDYIFQNISEFASKPCLINGPTGHVYTYSDVHLISRRIAASFQKLGVNQHDVVMILLSNCPEFVLTFLAASFRGATATAANPFFTPAEIAKQAKASNSKLIVTESRYVDKIKNLQNDDGVIIVCIDESAPIPEGCLRFTELTQSTDESDEDVIDISISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHKDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLGLIQRCKVTVAPMVPPIVLAIAKSPETEKYDLSSIKVVKSGAAPLGKELEDAVSSKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNKPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSELSEDEVKQFVSKQVVFYKRINKVFFVDSIPKAPSGKILRKDLREKLAKGF
>Mpyg14367.t1
MEKSGYGRDGIYRSLRPMLLLPKDSNTSLVSFLFRNSSSYLSKPALVDSDSGDSLSFSQLKSAVSRLANGFLRLGIRQHDVVLIFAPNSYQFPLCFLAVTAIGAVFTTANPLYTVNEVSKQIKDSKPKLIISVQQLFDTVKGFDLPVVLLGPGESVQISGSNSKILSFNNVMELSEPVSDLPLVDIKQSDTAALLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHAVFLCFLPMFHVFGLTVITYSQLQRGNTLISMAKFELETVLKSIEKYKVTYLWVVPPVFLALSKNTTVKKYGLSSLKYIGSGAAPLGKDLMEECGRNIPNVLLMQGYGMTETCGIVSLEDPRLGKRNSGSAGMLAPGIEAQIVSVETGKSQPPNQLGEIWVRGPNMMKGYLNNPQATKETLDKKGWVHTGDLGYFNEDGNLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPLPDEEAGEVPIAFVVRPPNSSITEEDIQKFIAKQVAPYKRLRRVSFINSVPKSAAGKILRRQLVQQVRSKM
>Mpyg22833.t1
MSPQEAITDQNQSSSDVIFRYKLPDIYIPNHLPLHDYIFENISEFAAKPCLINGPTGEIYSYADVHATSRKVAAGLQKLGVNQHDVVMLLLPNSPEFVLTFLAASFLGAITTAANPYFTTAEISKQAKASAAKLIVTQSQYADKVKNLQNDGVSIICTDSSDIPEGCLRFSELTKSGEEDHDSRQKISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHREDVILCVLPMSTLRVGATILLMPKFEITLLLEHIQRCKVTVAMVVPPIVLALAKSSETEKYDLSSVTIIKSGAAPLGKELEDAISAKFPNARLGQV
>Mpyg21357.t1
MEYQKQDNEYIFRSLYPAVPIPDKLTLPEFVLQGVEEFTEKVAFVEAVTGKAVTYGDVVRDTKRLAKALTSLGLRKGQVMVVVLPNVAEYGIIALGIMSTGGVFSGANPTALVSEIKKQVEASGARGIITDATNYEKVKTLGLPVIVLGEEKIEGAVNWKDLLEAGDKSGDNNKEEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVRSDMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVTMSRYDLRIFLNALIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGRSLPKNTSGELCVRSQCVMQGYFKNKEETEKTIDEEGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPVACVVMNPKAKEKEEDILNFVAANVAHYKKVRAVHFVDTIPKSLSGKIMRRLLRDKILSIHKK
>Mpyg20816.t1
MITAALHEPQIHKPADTSPAPIVSGDASPPSPRIFRSKLPDIGIPNHLPLHTYCFDKLSYVSDKPCLIVGSTGKSYTYGETHLMCRRVAAGLYKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTANPFYTSQELYKQLRSSGAKLIITHSQYVDKLRNIDDTKIGQDLTVITTDDPTPENWLPFSILTDETNPLEEYVDVGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNLYLKTNDVVLCVLPLFHIYSLNSVLLNTIRSGAAVVLMHKFEIGALLDLIQRHKVTMAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLQDSLRRRLPQAVLGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLETRISLGYNQPGEICIRGQQIMKEYLNDAEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELEALLINHHSIADAAVVPQTDEVAGEVPVAFVVRSNGNEITEEDIKEYIAKQVVFYKRLHKVFFVPSIPKSPAGKILRKDLKAKLC
>Mpyg22835.t1
MTEAGPVLVSLGLAKEPFPAKSGARGTVARNAEMKIVGPDTGASLPKNKSGEICIRGHQIMKGYLNDPVATASTIDNDGDIGFVDDDDEVFIVDRLKELIKYKGYQVAPGELESLLIAHPHINDVAVVGMKEEGVGEVPVAFVVRSKDSNICEDDIKNWCQN
>Mpyg22834.t1
MVVIYDHVATKAIDDQKQSSNDIIFRSKLPDIIIPSHLPLHDYIFENISEFASKPCLINGPTGEVYSYADVYARSHKIAAGLQKRGVNQHDVIMLLLPNSPEVVFTFLGASIIGAATTATNPFSTPAEISKQAKASAAKLIVTRSQYVDKVKNLQTYNVLIICTYSDDSSAVPEGCFQFSDMIQSGEEVPDPRVNSLPVISPDDIVALPYSSGTTGLPKGVIVGCLTKSDDE
>Mpyg22836.t1
MVLQQQTLFFTKKTDQESSHDFIFRSKLPDIFIPNHLPLTDYVFQKFSGEGDGDSTCLIDGATGRIFTYADVQISSRRIAAGIHRLGIRHRDVVMLLLPNSPEFSLSFLAVAYLGAVSTTANPFYTQPEITKQAKDSATKMIITKRCYVDKLTTLKENGVLIVCVDDGDDETKAATDDYMSFTELTQADETELPKPEISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLYLTKDDVILCFLPMFHIYALDALMLSAMRTGAALLIVPRFELNLVMELIQRYKVTVVPVAPPVVLAFVKSPDTERYDLSSVRMMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTVTGVSLPRNKSGEICVRGHQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPYIEDAAVVAMKDEVADEVPVAFVVRSEGSQLTEDDVKSYVNKQVVHYKRIKMVFFIEAIPKAVSGKILRKELRAKLETEYSK
MAPQQEVMEKQSNNSDVIFRSKLPDIYIPNHLPLHDYIFQNISEFASKPCLINGPTGHVYTYSDVHLISRRIAASFQKLGVNQHDVVMILLSNCPEFVLTFLAASFRGATATAANPFFTPAEIAKQAKASNSKLIVTESRYVDKIKNLQNDDGVIIVCIDESAPIPEGCLRFTELTQSTDESDEDVIDISISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHKDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLGLIQRCKVTVAPMVPPIVLAIAKSPETEKYDLSSIKVVKSGAAPLGKELEDAVSSKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNKPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSELSEDEVKQFVSKQVVFYKRINKVFFVDSIPKAPSGKILRKDLREKLAKGF
>Mpyg14367.t1
MEKSGYGRDGIYRSLRPMLLLPKDSNTSLVSFLFRNSSSYLSKPALVDSDSGDSLSFSQLKSAVSRLANGFLRLGIRQHDVVLIFAPNSYQFPLCFLAVTAIGAVFTTANPLYTVNEVSKQIKDSKPKLIISVQQLFDTVKGFDLPVVLLGPGESVQISGSNSKILSFNNVMELSEPVSDLPLVDIKQSDTAALLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHAVFLCFLPMFHVFGLTVITYSQLQRGNTLISMAKFELETVLKSIEKYKVTYLWVVPPVFLALSKNTTVKKYGLSSLKYIGSGAAPLGKDLMEECGRNIPNVLLMQGYGMTETCGIVSLEDPRLGKRNSGSAGMLAPGIEAQIVSVETGKSQPPNQLGEIWVRGPNMMKGYLNNPQATKETLDKKGWVHTGDLGYFNEDGNLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPLPDEEAGEVPIAFVVRPPNSSITEEDIQKFIAKQVAPYKRLRRVSFINSVPKSAAGKILRRQLVQQVRSKM
>Mpyg22833.t1
MSPQEAITDQNQSSSDVIFRYKLPDIYIPNHLPLHDYIFENISEFAAKPCLINGPTGEIYSYADVHATSRKVAAGLQKLGVNQHDVVMLLLPNSPEFVLTFLAASFLGAITTAANPYFTTAEISKQAKASAAKLIVTQSQYADKVKNLQNDGVSIICTDSSDIPEGCLRFSELTKSGEEDHDSRQKISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHREDVILCVLPMSTLRVGATILLMPKFEITLLLEHIQRCKVTVAMVVPPIVLALAKSSETEKYDLSSVTIIKSGAAPLGKELEDAISAKFPNARLGQV
>Mpyg21357.t1
MEYQKQDNEYIFRSLYPAVPIPDKLTLPEFVLQGVEEFTEKVAFVEAVTGKAVTYGDVVRDTKRLAKALTSLGLRKGQVMVVVLPNVAEYGIIALGIMSTGGVFSGANPTALVSEIKKQVEASGARGIITDATNYEKVKTLGLPVIVLGEEKIEGAVNWKDLLEAGDKSGDNNKEEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVRSDMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVTMSRYDLRIFLNALIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGRSLPKNTSGELCVRSQCVMQGYFKNKEETEKTIDEEGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPVACVVMNPKAKEKEEDILNFVAANVAHYKKVRAVHFVDTIPKSLSGKIMRRLLRDKILSIHKK
>Mpyg20816.t1
MITAALHEPQIHKPADTSPAPIVSGDASPPSPRIFRSKLPDIGIPNHLPLHTYCFDKLSYVSDKPCLIVGSTGKSYTYGETHLMCRRVAAGLYKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTANPFYTSQELYKQLRSSGAKLIITHSQYVDKLRNIDDTKIGQDLTVITTDDPTPENWLPFSILTDETNPLEEYVDVGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNLYLKTNDVVLCVLPLFHIYSLNSVLLNTIRSGAAVVLMHKFEIGALLDLIQRHKVTMAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLQDSLRRRLPQAVLGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLETRISLGYNQPGEICIRGQQIMKEYLNDAEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELEALLINHHSIADAAVVPQTDEVAGEVPVAFVVRSNGNEITEEDIKEYIAKQVVFYKRLHKVFFVPSIPKSPAGKILRKDLKAKLC
>Mpyg22835.t1
MTEAGPVLVSLGLAKEPFPAKSGARGTVARNAEMKIVGPDTGASLPKNKSGEICIRGHQIMKGYLNDPVATASTIDNDGDIGFVDDDDEVFIVDRLKELIKYKGYQVAPGELESLLIAHPHINDVAVVGMKEEGVGEVPVAFVVRSKDSNICEDDIKNWCQN
>Mpyg22834.t1
MVVIYDHVATKAIDDQKQSSNDIIFRSKLPDIIIPSHLPLHDYIFENISEFASKPCLINGPTGEVYSYADVYARSHKIAAGLQKRGVNQHDVIMLLLPNSPEVVFTFLGASIIGAATTATNPFSTPAEISKQAKASAAKLIVTRSQYVDKVKNLQTYNVLIICTYSDDSSAVPEGCFQFSDMIQSGEEVPDPRVNSLPVISPDDIVALPYSSGTTGLPKGVIVGCLTKSDDE
>Mpyg22836.t1
MVLQQQTLFFTKKTDQESSHDFIFRSKLPDIFIPNHLPLTDYVFQKFSGEGDGDSTCLIDGATGRIFTYADVQISSRRIAAGIHRLGIRHRDVVMLLLPNSPEFSLSFLAVAYLGAVSTTANPFYTQPEITKQAKDSATKMIITKRCYVDKLTTLKENGVLIVCVDDGDDETKAATDDYMSFTELTQADETELPKPEISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLYLTKDDVILCFLPMFHIYALDALMLSAMRTGAALLIVPRFELNLVMELIQRYKVTVVPVAPPVVLAFVKSPDTERYDLSSVRMMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTVTGVSLPRNKSGEICVRGHQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPYIEDAAVVAMKDEVADEVPVAFVVRSEGSQLTEDDVKSYVNKQVVHYKRIKMVFFIEAIPKAVSGKILRKELRAKLETEYSK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University