Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Megacarpaea delavayi
Species name
Megacarpaea delavayi is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Megacarpaea_delavayi.HIDH.fa
Download
>Mde002370.5.t1
MESEIASEHLPFCRIYKDGRVERLTGTDIIPASLDPTNDVVSKDIVYSPEHNLSVRLFLPHKSTELVAGNKLPLLIYIHGGAWIIESPFSPIYHNYVADVVKSANCLAVSIQYRRAPENPIPAAYEDSWSAIEWIFSHSDRSGPEDWINKHADFARVFIAGDSAGANTSHHMAIRAGKEKLEPKIKGIAVVHPAFWGTDPVDEYDVQDREIRNGIAEVWEKITSPNSVKGTDDPLFNVVGSGSDFSELGCEKVLVAVAGKDVFVRQGLGYAAKLEESAWKGKVEVIEEEEEGHVFHLQNPNCEKASKFLKEFVDFING
>Mde005602.1.t1
MRIRNYPNKLITRVRVYFDAFGFYFQLDPDNNLSVRIFLTEKAAETGAKLPLHGGGFVIETAFSPTYHNFITTAVSASHCVAVSVNYYRAPEHHIPIAYDDSWTALKWVFSHIAGSGSENLVNKHTDFNKVFLAGDNAGANIAHHMATRAAKEKLSPELSDSGIILVHPYFWSKTPIDEKETKDVTIRENIIYLLMMNN
>Mde007839.3.t1
MDSEIVADYSPLLKIYKSGRIERLMGETIVPPSSVPQNGVVSKDVVYSPDDNLSLRIYLPEKAAETEAKLPLLVYFHGGGFIIETAFSPTYHAFLTAAVSASDCVAVSVDYRRAPEHPIPISYDDSWTALKWVFSHIAGYGSEDWLHKHADFSKVFLAGDSAGANIAHHMAMRAAKEKLSPNWSDSGVSGIILVHPYFWSKTPIDEKETKDEALRSKIESIWTMASPNSKDGCDDPLINVVQSESSDLSGLGCGRVLVMVAEKDALARQGWGYAAKLEKSRWKGEAEVVESEGEDHVFHLMKPDCDKALEAMHKFSEFLKGHK
>Mde009272.5.t1
MGATMTNVTTINPNSTNIHGPVVDEVEGLIRVYKDGYVERPQLVPSVGPSLALELRVACSDVNIDKLTNVWARLYVPMMTTKSSVSKLPLLVYFHGGGFCVGSASWSCYHEFLARLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAIIWLNKARSDNLWAKLCDFGRIFLAGDSAGGNIAHHVAARLAAADDPALLKPLKIEGTILIQPFFGGEARMESERRVGNNKTSVLTLAASDAWWRLALPRGANREHPYCKPVKIKSTVMRTLVCVGEMDLLMDRDMEMCDGNEKLIKRVLYRGVGHAFQILGKSQLAKATTLEMLCHIDAFIHQYDPFN
>Mde015291.6.t1
MDSEIAFDRSPGYRVYKSGRIGRLIGETFVPPSLTPQNGVVSKDAVFSPEKNLSLRIYLPEKVVETSKKLPVLVYFHGGGFIIETAFSPTYHTFVTSAVAAADCLAISVDYRRAPEFPIPIPYEDSWDSLKWVFAHISGSGQENWINKHADFSKVFLAGDSAGGNIVHHLTIRAKREKLDSIISGIILIHPYFWGKTPIDELETRDETRRKRIEGSWGIASPNSENGADDPLINVVGSESSNISGLGCGRVLVMVAGDDNFVRQGLGYAAKLEKSEWEGEVEVMEIENESHVFHLKNPNSDNARKLVKKLAQFVNVRSILLEICVLY
>Mde018666.6.t1
MDSDSEIAFDYSPRFLVYKNGRIERLVTEIFVPPSLNPENGVVSKDAVYSPEKNLSLRIYLPQKAVETGEKEKKKLPLVVYFHGGGFIMETAFSPIYHAFLTTAVTAADCIAVSVDYRRAPEHPIPIAYEDSWDAIQWVFSHIAGSGPEDWLNENADFSRVFLAGDSAGANITHHMGIRARNFKISGMTLFHPYFLSKAPIDEEQEAGAVGYMEGIWEIANPNSENGVEDPWVNVVGSDLSGLGCGRVLVMVAGNDVLAKQGWIYAAELEKSGWEGKVEVMETEDEGHVFHIRIPDSDNARHVVHKFAEFVKDGV
>Mde022270.1.t1
MDSEIAFDCSPVFKLYKSGRIERLMGETTVTPSLTPENGVVSKDVVYSPDNNLSVRIFLPEKAAETGAKLPLLVYFHGGGFVIETAFSPTYHNFVTAAVSASYCVAVSVDYRRAPEHHIPIAYDDSWTALKWVFSHIAGSGSENWLNKHGDFSKVFLAGDSAGANIGHHMAMRAAKEKLSPELSDSGISGIILVHPYFWSKTPIDEKETKDVTIRTKIEAFWMMVSPNNKDGCDDPMINVVQSESVDLSGLGCGNVLVMVAEKDALARQGWGYAAKLEKSGWKGKVEVVESEGEDHVFHLTKPDCENALEAMKKFAVFLKGEK
>Mde078708.2.t1
MGATPLAHATTTNPNNTNMHGPVVDEVEGLIRVYKDGHVERSQFVPCVGPSLALELGVDCSDVHIDKLTNLWARLYVPMVTKSSVSNHDLPLLVYFHGGGFCVGSASWSCYHEFLAKLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAILWIKETRNDNLWAKKCDLGRIFLAGDSAGGNIAHHVAARLAAGSDLNPLKIEGTILIQPFFGGEARTESEMRVENNKKSSVLTLAASDAWWRLALSLGANREHPYCKPVKIAMRTLVCVAEMDVLMDREIEMCDSYEKVIKRVVYKGVGHAFQILDKSQLAHTTTLEMLCHIDCFIHHYDPYN
>Mde098206.1.t1
MQQLKPISISLSTQFLPHNTTKLVSFFSPMESIKKQVSIEVLPWLVVHSDGTLERLVGTEVCSPGLDQETRVLSKDIIIEPKTGLSARIYRPETIQTGKNLPLVLYFHGGAFVISSVAFPNYHNSVNKLVAEANVIAVSVDYR
>Mde327455.1.t1
MATISFSHNHQSSDNRRGGSHQHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTVHASAKVTAFDIKLSNDTSTRVYIPDASVTLPLLVYFHGGGFCVGSAAWSCYHDFLTNLAVKARCVVVSVNYRLAPEHRLPAAYEDGVNVVSWLLKQQISNGGYSWVSKCNLSNVFLAGDSAGANIAYQVAVRIATTASGKSVNTLNLKGIILIHPFFGGESRTSSEKQHNSKSSALTLSASDTYWRLSLPRGANRDHPWCNPLVNTAGFLREVKLPTTMVFMAEFDILKDRNLELCKMMRSHGKRVEGVVHGGVGHAFHILDNTSVSRDRIHDMMCRLHNFIHP
MESEIASEHLPFCRIYKDGRVERLTGTDIIPASLDPTNDVVSKDIVYSPEHNLSVRLFLPHKSTELVAGNKLPLLIYIHGGAWIIESPFSPIYHNYVADVVKSANCLAVSIQYRRAPENPIPAAYEDSWSAIEWIFSHSDRSGPEDWINKHADFARVFIAGDSAGANTSHHMAIRAGKEKLEPKIKGIAVVHPAFWGTDPVDEYDVQDREIRNGIAEVWEKITSPNSVKGTDDPLFNVVGSGSDFSELGCEKVLVAVAGKDVFVRQGLGYAAKLEESAWKGKVEVIEEEEEGHVFHLQNPNCEKASKFLKEFVDFING
>Mde005602.1.t1
MRIRNYPNKLITRVRVYFDAFGFYFQLDPDNNLSVRIFLTEKAAETGAKLPLHGGGFVIETAFSPTYHNFITTAVSASHCVAVSVNYYRAPEHHIPIAYDDSWTALKWVFSHIAGSGSENLVNKHTDFNKVFLAGDNAGANIAHHMATRAAKEKLSPELSDSGIILVHPYFWSKTPIDEKETKDVTIRENIIYLLMMNN
>Mde007839.3.t1
MDSEIVADYSPLLKIYKSGRIERLMGETIVPPSSVPQNGVVSKDVVYSPDDNLSLRIYLPEKAAETEAKLPLLVYFHGGGFIIETAFSPTYHAFLTAAVSASDCVAVSVDYRRAPEHPIPISYDDSWTALKWVFSHIAGYGSEDWLHKHADFSKVFLAGDSAGANIAHHMAMRAAKEKLSPNWSDSGVSGIILVHPYFWSKTPIDEKETKDEALRSKIESIWTMASPNSKDGCDDPLINVVQSESSDLSGLGCGRVLVMVAEKDALARQGWGYAAKLEKSRWKGEAEVVESEGEDHVFHLMKPDCDKALEAMHKFSEFLKGHK
>Mde009272.5.t1
MGATMTNVTTINPNSTNIHGPVVDEVEGLIRVYKDGYVERPQLVPSVGPSLALELRVACSDVNIDKLTNVWARLYVPMMTTKSSVSKLPLLVYFHGGGFCVGSASWSCYHEFLARLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAIIWLNKARSDNLWAKLCDFGRIFLAGDSAGGNIAHHVAARLAAADDPALLKPLKIEGTILIQPFFGGEARMESERRVGNNKTSVLTLAASDAWWRLALPRGANREHPYCKPVKIKSTVMRTLVCVGEMDLLMDRDMEMCDGNEKLIKRVLYRGVGHAFQILGKSQLAKATTLEMLCHIDAFIHQYDPFN
>Mde015291.6.t1
MDSEIAFDRSPGYRVYKSGRIGRLIGETFVPPSLTPQNGVVSKDAVFSPEKNLSLRIYLPEKVVETSKKLPVLVYFHGGGFIIETAFSPTYHTFVTSAVAAADCLAISVDYRRAPEFPIPIPYEDSWDSLKWVFAHISGSGQENWINKHADFSKVFLAGDSAGGNIVHHLTIRAKREKLDSIISGIILIHPYFWGKTPIDELETRDETRRKRIEGSWGIASPNSENGADDPLINVVGSESSNISGLGCGRVLVMVAGDDNFVRQGLGYAAKLEKSEWEGEVEVMEIENESHVFHLKNPNSDNARKLVKKLAQFVNVRSILLEICVLY
>Mde018666.6.t1
MDSDSEIAFDYSPRFLVYKNGRIERLVTEIFVPPSLNPENGVVSKDAVYSPEKNLSLRIYLPQKAVETGEKEKKKLPLVVYFHGGGFIMETAFSPIYHAFLTTAVTAADCIAVSVDYRRAPEHPIPIAYEDSWDAIQWVFSHIAGSGPEDWLNENADFSRVFLAGDSAGANITHHMGIRARNFKISGMTLFHPYFLSKAPIDEEQEAGAVGYMEGIWEIANPNSENGVEDPWVNVVGSDLSGLGCGRVLVMVAGNDVLAKQGWIYAAELEKSGWEGKVEVMETEDEGHVFHIRIPDSDNARHVVHKFAEFVKDGV
>Mde022270.1.t1
MDSEIAFDCSPVFKLYKSGRIERLMGETTVTPSLTPENGVVSKDVVYSPDNNLSVRIFLPEKAAETGAKLPLLVYFHGGGFVIETAFSPTYHNFVTAAVSASYCVAVSVDYRRAPEHHIPIAYDDSWTALKWVFSHIAGSGSENWLNKHGDFSKVFLAGDSAGANIGHHMAMRAAKEKLSPELSDSGISGIILVHPYFWSKTPIDEKETKDVTIRTKIEAFWMMVSPNNKDGCDDPMINVVQSESVDLSGLGCGNVLVMVAEKDALARQGWGYAAKLEKSGWKGKVEVVESEGEDHVFHLTKPDCENALEAMKKFAVFLKGEK
>Mde078708.2.t1
MGATPLAHATTTNPNNTNMHGPVVDEVEGLIRVYKDGHVERSQFVPCVGPSLALELGVDCSDVHIDKLTNLWARLYVPMVTKSSVSNHDLPLLVYFHGGGFCVGSASWSCYHEFLAKLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAILWIKETRNDNLWAKKCDLGRIFLAGDSAGGNIAHHVAARLAAGSDLNPLKIEGTILIQPFFGGEARTESEMRVENNKKSSVLTLAASDAWWRLALSLGANREHPYCKPVKIAMRTLVCVAEMDVLMDREIEMCDSYEKVIKRVVYKGVGHAFQILDKSQLAHTTTLEMLCHIDCFIHHYDPYN
>Mde098206.1.t1
MQQLKPISISLSTQFLPHNTTKLVSFFSPMESIKKQVSIEVLPWLVVHSDGTLERLVGTEVCSPGLDQETRVLSKDIIIEPKTGLSARIYRPETIQTGKNLPLVLYFHGGAFVISSVAFPNYHNSVNKLVAEANVIAVSVDYR
>Mde327455.1.t1
MATISFSHNHQSSDNRRGGSHQHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTVHASAKVTAFDIKLSNDTSTRVYIPDASVTLPLLVYFHGGGFCVGSAAWSCYHDFLTNLAVKARCVVVSVNYRLAPEHRLPAAYEDGVNVVSWLLKQQISNGGYSWVSKCNLSNVFLAGDSAGANIAYQVAVRIATTASGKSVNTLNLKGIILIHPFFGGESRTSSEKQHNSKSSALTLSASDTYWRLSLPRGANRDHPWCNPLVNTAGFLREVKLPTTMVFMAEFDILKDRNLELCKMMRSHGKRVEGVVHGGVGHAFHILDNTSVSRDRIHDMMCRLHNFIHP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University