Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Megacarpaea delavayi
Species name
Megacarpaea delavayi is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Megacarpaea_delavayi.4CL.fa
Download
>Mde000734.5.t1
MEDQKQHNEHIFRSLYPSVPIPDKLTLPEFVLQGAEEYKEKVAFVEAVTGKAVTYGEVVRDTKRLAKALKSLGLRKGQVMVVVLPNLAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGIITDSTNFEKVKTLGLPVIVLGEEKMEGAVNWKDLLEAGEKSGDNNREEILQTDLCSLPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVSSQMIGQIVTLGLIPFFHIYGIVGICFATMKNKGKVVAMSRYDLRIFLNAIITHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPDKGQGIAKRNSVGFILPNLEVKFIDPETGLSLPKNTPGELCVRSQCVMQGYFENKEETEKTIDEQGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPVACVVINPKAKEKEEDILNFVAANVAHYKKIRAVHFVDSIPKSLSGKIMRRLLRDKIIISMKKL
>Mde016052.3.t1
MITASLQEPQIHKPADTSPTVVSGDDHSPPPRIFRSKLPDIEIPNHLPLHTYCFDKLSYVSDNPCLIVGSTGKTYSYGETHLLCRRLASGLYKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTGNPFYTSQEIYKQLRSSGAKIIITHSQYVDKLRNFELKIGEDLTVITTDDPTPENCFPFSILTDETNPLTESVDIGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNLYLNSNDVVLCVLPLFHIYSLNSVLLNSIRCEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELEALLINHNSIADAAVVPQNDEVAGEVPVAFVVRSNGNEITEEDVKEYIAKQVYTISYFVFKN
>Mde016404.2.1.5c03c0a0.t1
MAAPHLHISPNSKTPMAHQNLPLWFSRETGIYTSKFPSVHLPVDPNLDAVSALFSYRHDGYDAAAAALVDSVTGFSISYIELQSMFKSMAAGIYHDLGIHKGDVVSLVLPNSVYFPLIFLSLISLGAIVTTMNPSSSLGEIKKQVSECNVGLAFTSPENSENLSSLGIMVIRVPESYDFDSIRIENPKFYAIIKGDFRFVPKPLIKQDDVAAIMYSSGTTGASKGVLLTHRNLISTMELFVRFEASQYEYPGSSNVYLAALPLCHIYGLSLFVLGLLSLGSTIVVMRRFDASDVINVIERFKITHFPVVPPMLMALTKKAKGVCSKVFKSLKQVSSGAAPLSWKFIEDFLGTLPHVDLIQVFVFIIGSLFMSTLPFIYEIAFLLSQGYGMTESTAVGTRGFNTQKLRKHSSVGLLAPNMQAKIVDWRSGSFLPPKNRGELWIQGPGVMKGYLNNPEATQMTIVEDSWLRTGDIAYFDEDGYLFIVDRIKEIIKYKGFQIAPADLEAVLVSHPLIIDAAVTSAPDEECGEIPVAFVVRRQETTLSEQDVISYVAAQVAPYRKVRKVVMVSFIPKSPAGKILRKELKRILTSCVSSRL
>Mde018086.4.t1
MEKSGYGRDGIYRSLRPTLVLPKDPNTSLVSFLFRNSSSYPSKPALVDSDSGDSLSFSQLKSAVSRLAQGFLRLGIRKNDVVLIFAPNSYQFPLCFLAVSAIGGIFTTANPLYTVNEVSKQIKDSNPKIIISVHESFDKIKGFDLPIVLLGSGESAQIPGSNSKILSFNDVMELTEPGSDLPIVEIKQSDTAALLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLAVITYSQLQRGSAVISMAKFELETLLKNIEKYRVTQLWVVPPVFLALSKQSIAKKYDLSSLKYIGSGAAPLGKDLMEECGRNIRNVLLMQGYGMTETCGIVSVEDPRLGKRNTGSAGMLAPGVEAQIMSVETGKSQPPNQLGEIWVRGPSMMKGYLNNPKATKETIDKKGWVHTGDLGYFNEDGNLFVVDRIKELIKYKAFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIAFVVRSPNSSITEEDIQKFIAKQVAPYKRLRRVSFINSVPKSAAGKILRRTLVQQVRSKM
>Mde020415.2.t1
MRNFNWQSCTWKQKAPPKVKSFLWKVAVGAMAVGERLRSRGVQVDDRCKRCNDIETPLHVLRDCEFAQSVWALAPVSGSLQASSALDFLTGIKTFVTLPVVGCSVSLMPWLLWNIWKARNLVIFKRTFFSPSEFVPSPPLLPVERVRLFTNVARKGDSFSCGFGWNLSESNGSIVFQGSSSAFWIRSALAGKALAGEALAGEALALLRAMEDAASQGFLDLCILSDSHVLVRTLSSGSELVEIAGILADIRAFLPSFRRVNFHFIPRFCNGLADALAKQALRALVIADGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPVTGDSLSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFIVKSKDSDLTEDEVKQFVSKQVVFYKRINKVFFTNSIPKAPSGKILRKDLRAKLANGLMNSEQST
>Mde038188.2.t1
MVLQQQTLFLTKKTTDQEPSQDFIFRSKLPDIFIPNHLPLTDYVFQKFSGHGDSTCLIDGSTGRIFTYADVQISSRRIAAGIYRLGIRHRDVVMLLLPNSPEFALSFLAVAYLGAVSTTANPFYTQPEITKQAKDSGAKMIITNRCYVDKLTNLQNDGVFIACVDDGGDVVSSKVANERYVSFAELTQADETELPKPEISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLYLTKDDVMLCFLPMFHIYALDALLLSAMRTGAALLIVPRFELNLVMELIQRYKVTVVPVAPPVVLAFVKSQETDRYDLSSVRMMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTITGISLPRNKSGEICVRGHQLMKGYLNDPEATERTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPYIEDAAVVAMKDEVADEVPVAFVVRSEGSELTEDDVSSFVSKQVVHYKRIKMVFFIEAIPKAVSGKILRKELRAKLETEYPK
MEDQKQHNEHIFRSLYPSVPIPDKLTLPEFVLQGAEEYKEKVAFVEAVTGKAVTYGEVVRDTKRLAKALKSLGLRKGQVMVVVLPNLAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGIITDSTNFEKVKTLGLPVIVLGEEKMEGAVNWKDLLEAGEKSGDNNREEILQTDLCSLPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVSSQMIGQIVTLGLIPFFHIYGIVGICFATMKNKGKVVAMSRYDLRIFLNAIITHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPDKGQGIAKRNSVGFILPNLEVKFIDPETGLSLPKNTPGELCVRSQCVMQGYFENKEETEKTIDEQGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPVACVVINPKAKEKEEDILNFVAANVAHYKKIRAVHFVDSIPKSLSGKIMRRLLRDKIIISMKKL
>Mde016052.3.t1
MITASLQEPQIHKPADTSPTVVSGDDHSPPPRIFRSKLPDIEIPNHLPLHTYCFDKLSYVSDNPCLIVGSTGKTYSYGETHLLCRRLASGLYKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTGNPFYTSQEIYKQLRSSGAKIIITHSQYVDKLRNFELKIGEDLTVITTDDPTPENCFPFSILTDETNPLTESVDIGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNLYLNSNDVVLCVLPLFHIYSLNSVLLNSIRCEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELEALLINHNSIADAAVVPQNDEVAGEVPVAFVVRSNGNEITEEDVKEYIAKQVYTISYFVFKN
>Mde016404.2.1.5c03c0a0.t1
MAAPHLHISPNSKTPMAHQNLPLWFSRETGIYTSKFPSVHLPVDPNLDAVSALFSYRHDGYDAAAAALVDSVTGFSISYIELQSMFKSMAAGIYHDLGIHKGDVVSLVLPNSVYFPLIFLSLISLGAIVTTMNPSSSLGEIKKQVSECNVGLAFTSPENSENLSSLGIMVIRVPESYDFDSIRIENPKFYAIIKGDFRFVPKPLIKQDDVAAIMYSSGTTGASKGVLLTHRNLISTMELFVRFEASQYEYPGSSNVYLAALPLCHIYGLSLFVLGLLSLGSTIVVMRRFDASDVINVIERFKITHFPVVPPMLMALTKKAKGVCSKVFKSLKQVSSGAAPLSWKFIEDFLGTLPHVDLIQVFVFIIGSLFMSTLPFIYEIAFLLSQGYGMTESTAVGTRGFNTQKLRKHSSVGLLAPNMQAKIVDWRSGSFLPPKNRGELWIQGPGVMKGYLNNPEATQMTIVEDSWLRTGDIAYFDEDGYLFIVDRIKEIIKYKGFQIAPADLEAVLVSHPLIIDAAVTSAPDEECGEIPVAFVVRRQETTLSEQDVISYVAAQVAPYRKVRKVVMVSFIPKSPAGKILRKELKRILTSCVSSRL
>Mde018086.4.t1
MEKSGYGRDGIYRSLRPTLVLPKDPNTSLVSFLFRNSSSYPSKPALVDSDSGDSLSFSQLKSAVSRLAQGFLRLGIRKNDVVLIFAPNSYQFPLCFLAVSAIGGIFTTANPLYTVNEVSKQIKDSNPKIIISVHESFDKIKGFDLPIVLLGSGESAQIPGSNSKILSFNDVMELTEPGSDLPIVEIKQSDTAALLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLAVITYSQLQRGSAVISMAKFELETLLKNIEKYRVTQLWVVPPVFLALSKQSIAKKYDLSSLKYIGSGAAPLGKDLMEECGRNIRNVLLMQGYGMTETCGIVSVEDPRLGKRNTGSAGMLAPGVEAQIMSVETGKSQPPNQLGEIWVRGPSMMKGYLNNPKATKETIDKKGWVHTGDLGYFNEDGNLFVVDRIKELIKYKAFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIAFVVRSPNSSITEEDIQKFIAKQVAPYKRLRRVSFINSVPKSAAGKILRRTLVQQVRSKM
>Mde020415.2.t1
MRNFNWQSCTWKQKAPPKVKSFLWKVAVGAMAVGERLRSRGVQVDDRCKRCNDIETPLHVLRDCEFAQSVWALAPVSGSLQASSALDFLTGIKTFVTLPVVGCSVSLMPWLLWNIWKARNLVIFKRTFFSPSEFVPSPPLLPVERVRLFTNVARKGDSFSCGFGWNLSESNGSIVFQGSSSAFWIRSALAGKALAGEALAGEALALLRAMEDAASQGFLDLCILSDSHVLVRTLSSGSELVEIAGILADIRAFLPSFRRVNFHFIPRFCNGLADALAKQALRALVIADGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPVTGDSLSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFIVKSKDSDLTEDEVKQFVSKQVVFYKRINKVFFTNSIPKAPSGKILRKDLRAKLANGLMNSEQST
>Mde038188.2.t1
MVLQQQTLFLTKKTTDQEPSQDFIFRSKLPDIFIPNHLPLTDYVFQKFSGHGDSTCLIDGSTGRIFTYADVQISSRRIAAGIYRLGIRHRDVVMLLLPNSPEFALSFLAVAYLGAVSTTANPFYTQPEITKQAKDSGAKMIITNRCYVDKLTNLQNDGVFIACVDDGGDVVSSKVANERYVSFAELTQADETELPKPEISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLYLTKDDVMLCFLPMFHIYALDALLLSAMRTGAALLIVPRFELNLVMELIQRYKVTVVPVAPPVVLAFVKSQETDRYDLSSVRMMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTITGISLPRNKSGEICVRGHQLMKGYLNDPEATERTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPYIEDAAVVAMKDEVADEVPVAFVVRSEGSELTEDDVSSFVSKQVVHYKRIKMVFFIEAIPKAVSGKILRKELRAKLETEYPK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University