Enzyme
The enzyme from alfalfa can methylate daidzein, genistein and 6,7,4'-trihydroxyisoflavone but not flavones or flavanones.
D7OMT
Enzyme
Isoflavone 7-O-methyltransferase
Enzyme name
EC:2.1.1.150
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase
Sysname
S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone [RN:R07375]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];7-methoxyisoflavone [CPD:C15616]
Product
Species information
Medicago truncatula
Species name
Barrel medic (Medicago truncatula) is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Medicago_truncatula.D7OMT.fa
Download
>rna-XM_013613349.3
MASTNNQLEATELFEGQSLLYMHMFGFLKSMALKWAIQLNIPDIIYNHGKPITLSDLVSTLQVPISKQSLVERLMRFLAHNGIFVIHEKGENDDDDDQAYALTPASKLLSKSCCKDHCLTPMVLMSTDPILMGKFHQLGDWICGEIPTLYEAALGSTVWEFLEGKPEYLSLFNQAMASDSQMVNLALKNCSKVFEGIDSIVDVGGGTGTTARIICEAFPKLKCVVYDLPQVVANLSSACDNLSYVGGDMFKSIPQADAIMLKWILHDWTDEICIKILKTCKESVSSNGKKGKVIIMDIIINEEDDEKDMTETKLCLDLIMMGINGKERTGKEWKHLFVEAGFKDYKIFPLFGFRSLIEAYP
>rna-XM_013613348.3
MVSTNDQLEALELFQGQSLLYTHMYASLKPMSLKCAVQLNIPEIIYNHGKPITLPDLVSTLKVPLAKSSLVKRLMRFLAHIGIFAIHGKGEDDHDQTYALTPASKLLSKSCSKDHCLTPMVLMCTDPIFMSLFHQLGDLIHGEVPNLSEGALGVTLWEFLEEKPAYSSLFNEAMASNSQMVSLALKNCSEVFEGIESIVDVGGGNGTTAKIICEAFPKVKCLVFDVPHVVANSSCESQNVSYVGGDIFKSIPKADAIMLKSILHDWSDENCIKILKTCKDSVSSKGRKGKVIIIDILINEKDDEKDITQQNLIMDISMMAFDGGKERTEKEWKHLFIEAGFKDYKIFPLFSYESLIEVYP
>rna-XM_013601496.3
MASKNDLYKPSELFQAQTHLYKIMYSYLNPMSVKWALDLKIPDIIHNHRQAITLSELISALKVPQSKETCVGRLMRLLAHIDFFAIVKIDETKEGYTLTPTSQLLVSTTDHCLSSMVRLLNIPPIVGSYNHLGKWTCGEDLTIVETALGPESYWDFIHQNSSYLKTFNDAMESDSHVVRLALRDCKSVFQGIGSLVDVGGGTGNTAKIICEAFPELKYIVLDLPQVVSGLTGTNNLSFVGGNMFKSIPQADAVSLKWVLHNWSDDDCIKILKNCKKAISGKEKGGKVIIIDAVINEKQDEHEMTEVKLLLDVVMMTCFNGKERNEKEWKQLFLQAGFKYYKIFLTFGFRSLIELYP
>rna-XM_013601497.3
MASKNDLYKPSELFQAQTHLYKIMYGFLNPMSVKWALDLKIPDIIHNHGHAMTLSELISSLKVPQSKETCVRRLMRLLAHIDFFAIVKIDETKEGYALTPTSQLLVSDTDHCLSSMVRLLNTPTLVDAYNHLGKWTCGEDLTIVETALGPESYWDFIHENSAYLKSFNDAMESDSHVVRLALRDCNSVFEGIGSLVDVGGGTGNTAKIICEAFPELKYTVLDLPQVVSGLTGSINLSFVGGNMFKSIPQADTVLLKWVLHNWGDDDCIKILKNCKKAISGKEKGGKVIIIDVVINEKQDEHEMTEVKLLLDVVMMTSLNGKERNEKEWKQLFLQAGFKYYKIFPTFGFRSLIELYP
>rna-XM_003621436.4
MASSINNRKPSEIFKAQALLYKNMYAFVDSMSLKWSIEMNIPNIIHNHGKPITLSNLVSILQIPSTKVDNVQRLMRYLAHNGFFEIITNQELENEEEAYALTVASELLVKGTELCLAPMVECVLDPTLSTSFHNLKKWVYEEDLTLFAVNLGCDLWEFLNKNPEYNTLYNDALASDSKMINLAMKDCNLVFEGLESIVDVGGGNGTTGKIICETFPKLTCVVFDRPKVVENLCGSNNLTYVGGDMFISVPKADAVLLKAVLHDWTDKDCIKILKKCKEAVTSDGKRGKVIVIDMVINEKKDENQLTQIKLLMNVTISCVNGKERNEEEWKKLFIEAGFQDYKISPFTGLMSLIEIYP
>rna-XM_003621830.4
MDSENEYKASELFVAQAHLYNQIFSFMRPVSIKWAVELGIPDIIQNHGKPITLPELVSALRIPEAKAGCVHSVMRLLAHNKIFAIVKIDDNKEAYALSPTSKLLVKGTDHCLTSMVKMVTNPTGVELYYQLTKWTSKEDLTIFDTTLWDFMQQNSAYAELFNDAMESDSNMMRFAMSDCKSVFEGITSLVDVGGGTGNTVKIISEAFPTLKCIVFDLPNVVEGLTGNNYLSFVGGNMFESIPQADAILLKWVIHNWNDDDCVKILKKCKEAASRQKKGGKVIIIDIVINEKQDEHEITEVKLCFDITMMANHNSRERDEKTWKKIITEAGFMSYKIFPIFGFRSLIELSV
>rna-XM_003621832.4
MGSENEHKASELFEVQAHLYNQLFSFLRPVSIKWAVELGIPDIIQNHGKPITLPELVSALRIPEAKAGCVHSVMRLLAHNKIFAIVKIDDNKEAYALSPTSKLLVKGTDHCLSSMVKLLTNPTRVEKHYQLSTWTSMEDLTIFETPLWDLILQNPTHSKLFNDAMESDSNMVRFAMSDCKSVFEGLTSLVDVGGGTGNTVKIICEAFPTLKCIVFDLPNVVEGLTGNNYLSFVGGNMFESIPQADAILLKWILHNWNDDDCVKILRNCKEAVSRKNKEGKVIIIDIVINEEQDEHEMTELKLFFDISMMANFGSTERDEKAWEKIITEAGFTSYKIFHIFGFKSLIELCV
>rna-XM_024770457.2
MASSINNRKASEIFKAQALLYKNMYAFIDSMSLKWSVEMDIPTIIYNHGKPITLSNLVSILQIPSTKVDNVQRLMRLLAHNGFFEIVTNQELENEEEAYALTVTSELLVKGTELCLAPMVECVLDPKFNVSFHNFKKWIYEEDLTLFATSLGCDLWEFLNKNPEYNRLFNDAMASDSKMINLALKDCNFVFEGLDSIVDVGGGNGTTGKIICETYPKLRCVVFDRPKVVENLCGSNNLTYVGGDMFISVPKADAVLLKWILHDWTDRDCIKILKKCKEAVTTEGKRGKVIVIDMVINEKKEENELTQIKLLMNVTISCLNGKERNEEEWKKLFMEAGFENYKISPCLLLFSDSSSLGFALLG
>rna-XM_003621440.4
MASSLNGRKPSEIFKAQALLYKHIFAFIDSMSLKWAVEMNIPNIIHNHGKPISLSNLVSILQVPSSKIGNVRRLMRYLAHNGFFEIITKEEESYALTVASELLVRGSDLCLAPMVECVLDPTLSGSYHELKKWIYEEDLTLFGVTLGSGFWDFLDKNPEYNRSFNDAMASDSKLINLALRDCDFVFDGLESIVDVGGGNGTTGKIICETFPKLKCIVFDRPQVVENLSGSNNLTYVGGDMFTSIPNADAVLLKYILHNWTDKDCTRILKKCKEAVTNDGKKGKVIIIDMVINEKKDENQVTQIKLLMDVNMACLNGKERNEEEWKKLFIEAGFQDYKISPLTGFLSLIEIYP
MASTNNQLEATELFEGQSLLYMHMFGFLKSMALKWAIQLNIPDIIYNHGKPITLSDLVSTLQVPISKQSLVERLMRFLAHNGIFVIHEKGENDDDDDQAYALTPASKLLSKSCCKDHCLTPMVLMSTDPILMGKFHQLGDWICGEIPTLYEAALGSTVWEFLEGKPEYLSLFNQAMASDSQMVNLALKNCSKVFEGIDSIVDVGGGTGTTARIICEAFPKLKCVVYDLPQVVANLSSACDNLSYVGGDMFKSIPQADAIMLKWILHDWTDEICIKILKTCKESVSSNGKKGKVIIMDIIINEEDDEKDMTETKLCLDLIMMGINGKERTGKEWKHLFVEAGFKDYKIFPLFGFRSLIEAYP
>rna-XM_013613348.3
MVSTNDQLEALELFQGQSLLYTHMYASLKPMSLKCAVQLNIPEIIYNHGKPITLPDLVSTLKVPLAKSSLVKRLMRFLAHIGIFAIHGKGEDDHDQTYALTPASKLLSKSCSKDHCLTPMVLMCTDPIFMSLFHQLGDLIHGEVPNLSEGALGVTLWEFLEEKPAYSSLFNEAMASNSQMVSLALKNCSEVFEGIESIVDVGGGNGTTAKIICEAFPKVKCLVFDVPHVVANSSCESQNVSYVGGDIFKSIPKADAIMLKSILHDWSDENCIKILKTCKDSVSSKGRKGKVIIIDILINEKDDEKDITQQNLIMDISMMAFDGGKERTEKEWKHLFIEAGFKDYKIFPLFSYESLIEVYP
>rna-XM_013601496.3
MASKNDLYKPSELFQAQTHLYKIMYSYLNPMSVKWALDLKIPDIIHNHRQAITLSELISALKVPQSKETCVGRLMRLLAHIDFFAIVKIDETKEGYTLTPTSQLLVSTTDHCLSSMVRLLNIPPIVGSYNHLGKWTCGEDLTIVETALGPESYWDFIHQNSSYLKTFNDAMESDSHVVRLALRDCKSVFQGIGSLVDVGGGTGNTAKIICEAFPELKYIVLDLPQVVSGLTGTNNLSFVGGNMFKSIPQADAVSLKWVLHNWSDDDCIKILKNCKKAISGKEKGGKVIIIDAVINEKQDEHEMTEVKLLLDVVMMTCFNGKERNEKEWKQLFLQAGFKYYKIFLTFGFRSLIELYP
>rna-XM_013601497.3
MASKNDLYKPSELFQAQTHLYKIMYGFLNPMSVKWALDLKIPDIIHNHGHAMTLSELISSLKVPQSKETCVRRLMRLLAHIDFFAIVKIDETKEGYALTPTSQLLVSDTDHCLSSMVRLLNTPTLVDAYNHLGKWTCGEDLTIVETALGPESYWDFIHENSAYLKSFNDAMESDSHVVRLALRDCNSVFEGIGSLVDVGGGTGNTAKIICEAFPELKYTVLDLPQVVSGLTGSINLSFVGGNMFKSIPQADTVLLKWVLHNWGDDDCIKILKNCKKAISGKEKGGKVIIIDVVINEKQDEHEMTEVKLLLDVVMMTSLNGKERNEKEWKQLFLQAGFKYYKIFPTFGFRSLIELYP
>rna-XM_003621436.4
MASSINNRKPSEIFKAQALLYKNMYAFVDSMSLKWSIEMNIPNIIHNHGKPITLSNLVSILQIPSTKVDNVQRLMRYLAHNGFFEIITNQELENEEEAYALTVASELLVKGTELCLAPMVECVLDPTLSTSFHNLKKWVYEEDLTLFAVNLGCDLWEFLNKNPEYNTLYNDALASDSKMINLAMKDCNLVFEGLESIVDVGGGNGTTGKIICETFPKLTCVVFDRPKVVENLCGSNNLTYVGGDMFISVPKADAVLLKAVLHDWTDKDCIKILKKCKEAVTSDGKRGKVIVIDMVINEKKDENQLTQIKLLMNVTISCVNGKERNEEEWKKLFIEAGFQDYKISPFTGLMSLIEIYP
>rna-XM_003621830.4
MDSENEYKASELFVAQAHLYNQIFSFMRPVSIKWAVELGIPDIIQNHGKPITLPELVSALRIPEAKAGCVHSVMRLLAHNKIFAIVKIDDNKEAYALSPTSKLLVKGTDHCLTSMVKMVTNPTGVELYYQLTKWTSKEDLTIFDTTLWDFMQQNSAYAELFNDAMESDSNMMRFAMSDCKSVFEGITSLVDVGGGTGNTVKIISEAFPTLKCIVFDLPNVVEGLTGNNYLSFVGGNMFESIPQADAILLKWVIHNWNDDDCVKILKKCKEAASRQKKGGKVIIIDIVINEKQDEHEITEVKLCFDITMMANHNSRERDEKTWKKIITEAGFMSYKIFPIFGFRSLIELSV
>rna-XM_003621832.4
MGSENEHKASELFEVQAHLYNQLFSFLRPVSIKWAVELGIPDIIQNHGKPITLPELVSALRIPEAKAGCVHSVMRLLAHNKIFAIVKIDDNKEAYALSPTSKLLVKGTDHCLSSMVKLLTNPTRVEKHYQLSTWTSMEDLTIFETPLWDLILQNPTHSKLFNDAMESDSNMVRFAMSDCKSVFEGLTSLVDVGGGTGNTVKIICEAFPTLKCIVFDLPNVVEGLTGNNYLSFVGGNMFESIPQADAILLKWILHNWNDDDCVKILRNCKEAVSRKNKEGKVIIIDIVINEEQDEHEMTELKLFFDISMMANFGSTERDEKAWEKIITEAGFTSYKIFHIFGFKSLIELCV
>rna-XM_024770457.2
MASSINNRKASEIFKAQALLYKNMYAFIDSMSLKWSVEMDIPTIIYNHGKPITLSNLVSILQIPSTKVDNVQRLMRLLAHNGFFEIVTNQELENEEEAYALTVTSELLVKGTELCLAPMVECVLDPKFNVSFHNFKKWIYEEDLTLFATSLGCDLWEFLNKNPEYNRLFNDAMASDSKMINLALKDCNFVFEGLDSIVDVGGGNGTTGKIICETYPKLRCVVFDRPKVVENLCGSNNLTYVGGDMFISVPKADAVLLKWILHDWTDRDCIKILKKCKEAVTTEGKRGKVIVIDMVINEKKEENELTQIKLLMNVTISCLNGKERNEEEWKKLFMEAGFENYKISPCLLLFSDSSSLGFALLG
>rna-XM_003621440.4
MASSLNGRKPSEIFKAQALLYKHIFAFIDSMSLKWAVEMNIPNIIHNHGKPISLSNLVSILQVPSSKIGNVRRLMRYLAHNGFFEIITKEEESYALTVASELLVRGSDLCLAPMVECVLDPTLSGSYHELKKWIYEEDLTLFGVTLGSGFWDFLDKNPEYNRSFNDAMASDSKLINLALRDCDFVFDGLESIVDVGGGNGTTGKIICETFPKLKCIVFDRPQVVENLSGSNNLTYVGGDMFTSIPNADAVLLKYILHNWTDKDCTRILKKCKEAVTNDGKKGKVIIIDMVINEKKDENQVTQIKLLMDVNMACLNGKERNEEEWKKLFIEAGFQDYKISPLTGFLSLIEIYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University