Enzyme
The enzyme catalyses the 4'-methylation of naringenin. In vitro it catalyses the 4'-methylation of apigenin, quercetin, daidzein and genistein.
FOMT4
Enzyme
Flavonoid 4'-O-methyltransferase
Enzyme name
EC:2.1.1.231
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + a 4'-hydroxyflavanone = S-adenosyl-L-homocysteine + a 4'-methoxyflavanone [RN:R09792]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];4'-methoxyflavanone [CPD:C19895]
Product
Species information
Amphicarpaea edgeworthi
Species name
Chinese hog-peanut (Amphicarpaea edgeworthii) is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Amphicarpaea_edgeworthi.FOMT4.fa
Download
>Ae.00020425
MDPSGTSNGRSLKTLPQQIEENSVRATFELTREDLEKIKKRWILHNWIHKDCIKILKNCKEAISNNGKRGKVIIIDVVINEKQEEHKVTELKLVMDITMACVNGKERNEEEWKKLFIEAGFQDYKISPLTGYLSLIEIYP
>Ae.00020506
MASNNGRKASEIFEGQHLLYRHMYAHVDSMILKCIVQLGIPDIIHNHGQPITLPKLVSILQVPPNKVSGLQSLMSYLAHNGFFEIVRIHDNNNNNIEEKELAYALTAASELLVKGSDLCLAPMVECFLDPTFSSSWHHLKKWIYEDDLTLFGISLGSHLWDFLDKNPAFNKSVNEAMASDSQMMNLALRDCNWVFEGLESIVDVGGGTGTTAKIICEAFPNLKCRVLELPHVIENLSGSNNLTYVAGDMFKSIPNADAWILHDWNDSDCRKILKNCKEAISSKSKRGKVIVIDVVINENQDEHEVTRLKLLMNVHMTCLINGKERREEEWKKLFVEAGLQSYKISPLTGHLSLIEIYP
>Ae.00020513
MAKEGKIIIIDIVINEKQDEHKVNELKLLWDVTMACVLNGKERNEEEWKTPFMEAGFQDYKISLLTGLSCMLPNLGFCPNTYETKLEKAICTLGHGNQDWHRVIDKDYLELELVNFERRSVVRISDPSTH
>Ae.00020313
MASSSMNGRNASEIFQGQALLYKHLLAFIDSKCLKLMVELDIPDIIHKHGQPITFLELVSILQVPSTKIGHVQSFMCYLAHQGFFERVRIHEKEIYALTAASELLLKSSEVCLVPAVEHFLDPTVSSSWNHLKKWVHEEDLTLLEVSTGSTLWNFLNKDSAFNKSFNETMACDSQLMNLALRNCNWVFQGLESIVDVGGGIGTTANIICEVFPNLKCIVLERPHVVENLSGNNNLTYVGGDMFKSIPKADAVLLKLVLHNWNDKDCMKILENCKEAISSKSKTGKVVVIDTVINENEEEHEVTRLKLLMDVHMACLINEKERREEDWKKLILEAGFQSYKISPFTGYLSLVEIYP
>Ae.00020302
MASSSLNGRNASEIFQGQTLLYRYVFSHIDSMCLKCIVELGIPDIIHKHDQPITLSELVSILKVPSARVGHVQSLMRYMAHNGFFERVRIHEEKEAYALTAASELLVKSSDLCLTPMVDFVLDPTLLGSFQQMNKWVYEEDLSVHDISLGSNLWDFLNKNPAYNELFNEWMASDSQISNFALRDCKLVFEGLESIVDVGGGTGATVKIICQAFPNMKCIVFDRPQVVENLSGNNSFTYVGGDMFKSIPKADAILLKMILHNWNDDDCRKILENCKEAILGKGKIGKIIVIDVVINENQDEREVTGLKLLMNLNMACVFNGKERREEEWKKLFVEAGFQSYNISPLTAHFSLIEIYP
>Ae.00020372
MVSNNGRKASEIFQGQALLYRYVFAFVDSMRLKWIVELYIPDIIHNHGQPITLSELVSILQVPPARFGHVQNLMRYMAHNGFFERVRIHEEKEAYSLTAASELLVKSSDLCLTPMVEHILDPTLSASFHQMKKGSNLWDFLDKNPANNELFNEAMARDSQMSNLALRDCKSVFEGLESIVDVGGGTGATAKMICEAFPDLKCTVLDRPQVVENLKKATI
>Ae.00012221
MGSMNNNQNENELLEGQALLYMQLFAYLRPMCLKWVVQLGIPDIIQNHAKPITLSELVSTLQIPPAKACLVQRFMRFLAHNGIFDIHESQKEDHELAYALTPASKLLVSGSDHCLSPMVLLNTDPLVTSTYHHLGEWIRGEDPTLYETALGTTIWGLFEEKPTYMSLFNEAMASDSQMVDLALKNCTSVFEELDSIVDVGGGTGTTARIICEAFPKLKCVVLDLPHVVANLKGSNNLSFVGGDMFNSIPQADAILLKWVLHDWNDENCIKILQQCRDSIVSKGSIGKVIIIDAVINEKLDDRNMTQTKLSLDIIMLTMNGRERTENEWKQLFIEAGFKHHKIFPLFGFRSLIEVFP
>Ae.00012288
MGSMNNNQKEIELFEGQALLYMQLYGNLRPMCLKWAVQLGIPDIIHNHGKPITLSQLVSTLQIPPTNAAFVQRFMRFLAHNGIFDIHESQKDHESAYALTPASKLLVNSSDHCLSPMVLAFTDPLRNVKYHHLGEWIRGEQATVFETAHGTSSWGLLEKNPEYFSLFNEAMASDSRIVDLALKNCTSVFEGLDSMVDVGGGTGTTARIICEAFPKLKCVVLDLPRILKKCKDSVSNKGNGGKVIIIDAVIDEKLDDQNMTQTKLSLDIIMMTMNGRERTENEWKQLFVEAGFKHYKIFPIFGFRSLIEVYP
>Ae.00012477
MGSNSMNNQNAIEFFHGQALLYTQIYGCLKPMCLKWVVQLGIPDIIHNHGKPITLSELVSTLQIPPAKANFVQRFMRFLAHNGIFDIRESQEEDHESTYALTPASKLLVSGSDHCLSPMVLFNTDSAVTNTYHHFENWIRREDTTLYETAVGTTMWGYLEEKPKYLSHFNEAMASDSRIVDLALKNCTSVFEGLDSIVDVGGGTGTTAKIICETFPKLKCVVFDLPHVVANLTGNDNLSFVGGDMFNFIPQADAVLLKWVLHNWNDEYCIMILKKCKDSISNKGTGGKVVIIDAVINEKLDDPDMIQAKITFDIIMMTMNGRERTEKEWKQLFIEAGFKHYKIFPIFGFRSLIEVYP
MDPSGTSNGRSLKTLPQQIEENSVRATFELTREDLEKIKKRWILHNWIHKDCIKILKNCKEAISNNGKRGKVIIIDVVINEKQEEHKVTELKLVMDITMACVNGKERNEEEWKKLFIEAGFQDYKISPLTGYLSLIEIYP
>Ae.00020506
MASNNGRKASEIFEGQHLLYRHMYAHVDSMILKCIVQLGIPDIIHNHGQPITLPKLVSILQVPPNKVSGLQSLMSYLAHNGFFEIVRIHDNNNNNIEEKELAYALTAASELLVKGSDLCLAPMVECFLDPTFSSSWHHLKKWIYEDDLTLFGISLGSHLWDFLDKNPAFNKSVNEAMASDSQMMNLALRDCNWVFEGLESIVDVGGGTGTTAKIICEAFPNLKCRVLELPHVIENLSGSNNLTYVAGDMFKSIPNADAWILHDWNDSDCRKILKNCKEAISSKSKRGKVIVIDVVINENQDEHEVTRLKLLMNVHMTCLINGKERREEEWKKLFVEAGLQSYKISPLTGHLSLIEIYP
>Ae.00020513
MAKEGKIIIIDIVINEKQDEHKVNELKLLWDVTMACVLNGKERNEEEWKTPFMEAGFQDYKISLLTGLSCMLPNLGFCPNTYETKLEKAICTLGHGNQDWHRVIDKDYLELELVNFERRSVVRISDPSTH
>Ae.00020313
MASSSMNGRNASEIFQGQALLYKHLLAFIDSKCLKLMVELDIPDIIHKHGQPITFLELVSILQVPSTKIGHVQSFMCYLAHQGFFERVRIHEKEIYALTAASELLLKSSEVCLVPAVEHFLDPTVSSSWNHLKKWVHEEDLTLLEVSTGSTLWNFLNKDSAFNKSFNETMACDSQLMNLALRNCNWVFQGLESIVDVGGGIGTTANIICEVFPNLKCIVLERPHVVENLSGNNNLTYVGGDMFKSIPKADAVLLKLVLHNWNDKDCMKILENCKEAISSKSKTGKVVVIDTVINENEEEHEVTRLKLLMDVHMACLINEKERREEDWKKLILEAGFQSYKISPFTGYLSLVEIYP
>Ae.00020302
MASSSLNGRNASEIFQGQTLLYRYVFSHIDSMCLKCIVELGIPDIIHKHDQPITLSELVSILKVPSARVGHVQSLMRYMAHNGFFERVRIHEEKEAYALTAASELLVKSSDLCLTPMVDFVLDPTLLGSFQQMNKWVYEEDLSVHDISLGSNLWDFLNKNPAYNELFNEWMASDSQISNFALRDCKLVFEGLESIVDVGGGTGATVKIICQAFPNMKCIVFDRPQVVENLSGNNSFTYVGGDMFKSIPKADAILLKMILHNWNDDDCRKILENCKEAILGKGKIGKIIVIDVVINENQDEREVTGLKLLMNLNMACVFNGKERREEEWKKLFVEAGFQSYNISPLTAHFSLIEIYP
>Ae.00020372
MVSNNGRKASEIFQGQALLYRYVFAFVDSMRLKWIVELYIPDIIHNHGQPITLSELVSILQVPPARFGHVQNLMRYMAHNGFFERVRIHEEKEAYSLTAASELLVKSSDLCLTPMVEHILDPTLSASFHQMKKGSNLWDFLDKNPANNELFNEAMARDSQMSNLALRDCKSVFEGLESIVDVGGGTGATAKMICEAFPDLKCTVLDRPQVVENLKKATI
>Ae.00012221
MGSMNNNQNENELLEGQALLYMQLFAYLRPMCLKWVVQLGIPDIIQNHAKPITLSELVSTLQIPPAKACLVQRFMRFLAHNGIFDIHESQKEDHELAYALTPASKLLVSGSDHCLSPMVLLNTDPLVTSTYHHLGEWIRGEDPTLYETALGTTIWGLFEEKPTYMSLFNEAMASDSQMVDLALKNCTSVFEELDSIVDVGGGTGTTARIICEAFPKLKCVVLDLPHVVANLKGSNNLSFVGGDMFNSIPQADAILLKWVLHDWNDENCIKILQQCRDSIVSKGSIGKVIIIDAVINEKLDDRNMTQTKLSLDIIMLTMNGRERTENEWKQLFIEAGFKHHKIFPLFGFRSLIEVFP
>Ae.00012288
MGSMNNNQKEIELFEGQALLYMQLYGNLRPMCLKWAVQLGIPDIIHNHGKPITLSQLVSTLQIPPTNAAFVQRFMRFLAHNGIFDIHESQKDHESAYALTPASKLLVNSSDHCLSPMVLAFTDPLRNVKYHHLGEWIRGEQATVFETAHGTSSWGLLEKNPEYFSLFNEAMASDSRIVDLALKNCTSVFEGLDSMVDVGGGTGTTARIICEAFPKLKCVVLDLPRILKKCKDSVSNKGNGGKVIIIDAVIDEKLDDQNMTQTKLSLDIIMMTMNGRERTENEWKQLFVEAGFKHYKIFPIFGFRSLIEVYP
>Ae.00012477
MGSNSMNNQNAIEFFHGQALLYTQIYGCLKPMCLKWVVQLGIPDIIHNHGKPITLSELVSTLQIPPAKANFVQRFMRFLAHNGIFDIRESQEEDHESTYALTPASKLLVSGSDHCLSPMVLFNTDSAVTNTYHHFENWIRREDTTLYETAVGTTMWGYLEEKPKYLSHFNEAMASDSRIVDLALKNCTSVFEGLDSIVDVGGGTGTTAKIICETFPKLKCVVFDLPHVVANLTGNDNLSFVGGDMFNFIPQADAVLLKWVLHNWNDEYCIMILKKCKDSISNKGTGGKVVIIDAVINEKLDDPDMIQAKITFDIIMMTMNGRERTEKEWKQLFIEAGFKHYKIFPIFGFRSLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University