Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Malus domestica
Species name
Apple (Malus domestica) is a species of eudicot in the family Rosaceae (rose family).
Species info
Gene sequence info
Malus_domestica.OMT.fa
Download
>rna-XM_008345653.3
MGLNNGEVGAISHELLGAQAHVWNHMFQFINSMSLKCAVQLGIPDVIHNHGQPISLSELVARLNIHPSKAHFMSRLMRILVHSDFFAQHDHVHHDRDDAEEEVAVVLYSLTPASGLFLKDGPLNTTPFLLMILDQVITDPFHSMGNWLQMNCGDDLVPCTPFEVANGMPFWELSAKKPRFGDLFNEAMEADSKLIAGVVEECGGVFEGLKSLVDVGGGTGTMAKAIANAFPNINCTVFDQPHVVADLEGMTHNLGFVGGDMFEEIPPANAILLKWILHDWNDEESVKILKKCREAIFLNKNEGRKKKIIIIDIVVGYADNKTKVDKKSIETQLMFDMLMMSTITGKERSESEWEKIFLAAGFSHYNITHMLGLRSLIEVYP
>rna-NM_001328875.1
MSLSNEVGATSHELLGAQAQLWNHIFQFINSMSLKCAVQLGIADVIHNHGQPISLSELMAGLKVHPSKAHFVSRLMRILVHSNFFAQHHHVHHDRADVEEEETVVLYSLTPASRLLLKDGSLNTTPFLLMILDPVVTTPFHLMGAWLKINGGDDPAATCTPFEMENGMPFWELGAREPRFGNLFNEAMEADSKLIGRVVVEECGGVFEGLKSLMDVGGGSGTMAKAIANAFPNINCTVFDQPHVVAGLQGTTHNLGFMGGDMFEEIPPADAILLKWIMHDWNDEESVTILKKCREAISLSKNEGGNKKIIIIDIVVGYVDNKKKMMDKKSIETQLMFDMLMMSILPGKERSKSEWEKIFFAAGFTHYNITHTLGFRSLIEVYP
>rna-XM_008394713.3
MGLSDGEVGSTSHELLEAQAQIWNHMFQFINSMALKCAAQLGIPDVIHNHGQPISLSELIAALNVHPSRAHFVSRLMRILVHSDFFAQHHHVHHDCDDVEEEEAVVLYSLTPTSRLLLKDGPSNTTPLILMILDPVLTTPFHLMGAWLQMNGGDDPATICTPFEMENGMPFWDLAAQEPRFGNLFDEAMEADSKLLGREVVKECGGVFEGLKSLVDVGGGTGTMAKAIANAFPSINCIVFDQPHVVADLQGTTHNLGFVGGDMFVEIPPANAILLKWILHDWSDEESVKILKKCREAILLSKNDEGNKKIIIIDIVVGHVDNKEKMVDKKSIETQLMFDVLMMSAFTGKERSESEWKTIFLAAGFTHYNMTHMFGFRSLIELYP
>rna-XM_029092746.1
MGLSNGEVGATSHELLGAQAQIWNHMFQFINSMALKCAVQLGIPDVIHNHGQPISLSELIAALNVHPSRAHFVSRLMRILVHSDFFAQHHHVHRGCDDMEEEEAVVLYSLTPTSRLLLKDGPSNTTPLILMILDPVLTTPFHLMGAWLQMNGGDDPATICTPFKMENGMPFWDLAAQEPRFGNLFDEAMEADSKLLGREVVEECGGVFEGLKSLVDVGGGTGTMAKAIANAFPSINCIVFDQPHVVANLLGSTHNLGFVGGDMFVEIPPANAILLKWILHDWSDEESVKILKKCREAILLSKNDEGNKKIIIIDIVVGHVDKKEKMVDKKSIETQLMFDMLMMSTVTGKERSESEWKKIFLAAGFTHYNITHTFGFRSLIELYP
>rna-XM_008360216.3
MEEKQRELTWEEEEEGATAEMWKYVFGFTEIAVVRCAIDLGIAEAIENHGSPMTLLELSTALSCDPSHLYRIMRVLVHRKIFKEKPTQSGSNGYAQTPLSRRLLKSAENSMVDLLLMGSNPVMMAPYLRLSTQVQRNTSDAVFDEVHGSDLWNYGAENPDHGKAFNDSMACDARLAVPAALESCPEAFKGIETIVDAGGGNGTTARLLVEACPWITKGIIFDLPHVVSTIPECDRIEKIGGDFFKCIPKADAVVMMWILHDWTDEECISILKNCREAIPNDKGKVIIIDAVVEDNEKDYNKLTRVKLMLDIAMMNGTKGKERTAKEWEYVIREAGFSRHTITPTRTVQSVIQVFP
>rna-XM_008384232.3
MDTQRETEDTKRELTSEEEEERAKVDMWKYVFGFVEIAVVKCAIELGIADAIEIHGSPMTLLELSSALSCDPSHLYRVMRVLVHLKIFKEKTTELGPKGYAQTPLSKRLLKSGENSMAALILLESSPVMLAPWHGLSARLRGNSNPSFEAVHGEDLWSFAAANPDHSKLINDAMACDARVAVPAVIESCLEVFKGLETIVDVGGGDGTTLRLLVETCPWIRGINFDRPHVVSVAHECDRIENVGGDFFYCVPKADAAIIMWVLHDWGDDDCIRILKKCREAIPNDKGKVIIIEAVIEEDGKEDNKLADVRLMLDMVMLAHTNTGKERTFKEWGYVLGEAGFSRYTITPIHAVQSVIQAFP
>rna-XM_029103169.1
MEGDEARDLFGAQSHLYKHVFSFITSMSLKCVVQLGIPDIIDRHGQPITLPDLVTALQIHPAKTGNVHRLMRLMVHSGFFARKQVPKNHVEADEGEEEAYDLTPSSTLLLKDKVPSLSSFVLGMLDPASAAPWQFLGNWFRGTEVTPFESAHGMGFWEYAEGNPEFNSLFNKAMASDSGMMNLVIRDCKPIFDGLSSLVDVGGGTGKVARILCDAFPQLKCTVLELPHVVADLPDCENLKFVRGDMFQGIPPADAVFLKLILHDLSDEECLKVLKKCREAIASNGQGKVIIIDIVMNEEKDEHEITEAKLLFDLLMMVVITGRERSEKDWKKLFLEAGFSSYKVTPIFGLRSLIEVFL
>rna-XM_029102218.1
MEDNQSVLTWEEEEEHVKVDVWKYVFGFVEIVVIKCAIELGIAEAIETRGSPMTLLELSSALRCDPSHIYRIMRVLVHLKIFKEQTTIQLGSKSYAQTPLSRLLLKSGENSMAELILLESSPTMLAPWHSLSSRVQGNLRNPVFEELHGKDLWSFGVANPDHNKLFNEAMACDARLAVPALVKSCVKVFKGVGTLVDVGGGNETTLRLLVEACPWIQGINFDLPHVVSDAQKPDRIEYVGGNMFDCVPKADAIIIKWVLHDWGDDDCIRILKKCREAIPIDKGKVIIVEAVIDEKDEKANSKLKKARLMLDMVMIAHTGTGKERTMEEWEYVLGEAGFSRHTITPIHTIQSVIQAFP
>rna-XM_008360210.3
MEDTQRVLTWEEEEEHAKVDVWKYVFGFVEIAVVKCAIELGIAEAIESHGSPMTLLELSSALSCDPSHLYRVMRVLVHLKLFKEITTNQLGSKGYAQTPLSHRLLKSGENSMVALILLESSPVMLAPWHGLSARIRGNISNQLFEEVHGEDLWSFGAANPDHSKLFNDAMTCDVKAAVPAVIKSCIEVFKGLETIVDVGGGNGTMLRLLVEGCPWIRGINFDLPHVVSAAQDCDRVENVGGDMFDRVPKADAVIIKGVLHNWGDDDCIRILKKCREAVPKDTGKVIIIDAVIDEKYEKEDKKLANLKLMLDMVMIAHTNKGKERSLKEWEYVLGGAGFSGHTITPVPAIQYSVIQAFP
>rna-XM_029107936.1
MEMQEATEVEASLRGQADIWKYMLGFADSMALKCAVELRIADIIHSHSPTDGASNSKPMITLSQVASSIAPSPDMTYLTRIMRLLVRRNIFAIHHPSDGGTLYGLTHSSRWLLHNAELSLAPMLMMENHPCLMAPWHYFGQCVKEGGPYAFKMAHGLEIWDYASQNPEFNKLFNDGMACTTRVVMKAILTGYEHGFDGVGSLVDVGGGTGSAVAEIVKSYPNIKGFNFDLPHVVATAPVYHGVSHVSGDMFEGSIPNADAVFMKRIMHNWSDNDCIKILKNCRKAIPEKSGKIIIVDIVLEPNGEGILDDTRLVFDLLMIAHASGGRERTETEWKNILEEGGFPRYKVIKIPALASIVEAYPM
>rna-XM_008367216.3
MEMQEATEVEASLRGQADIWKYMFGFADSMALKCAVELRIADIIHSHSPTDGASNSRPMITLSQLASSIAPSPDMTYLTRIMRLLVRRNIFAIHHSSDGEEPLYGLTHSSRWLLHNTELSLAPMLVMENHPCLMAPWHYFSQCVKEGGPYAFKMAHGLEIWDYASQNPEFNKLFNDGMACTARVVMKAILTGYEHGFDGVGSLVDVGGGTGSAVAEIVKSYPNIKGFNFDLPHVVATAPVYHGVSHVGGDMFEGSIPNADAVFMKWIMHDWSDSDCIKILKNCRKAIPEKSGKIIIVDIVLEPNGEGILDDTRLVFDLLMIAHTSGGRERTETEWKNILEEGGFPRYKVIKIPALASIVEAYPM
>rna-XM_008359596.3
MQEEPEIEASLRGQADIWKYMFGFADSMALKCAVELRIADIIHSHRPSDGASNSNPMIALSQLASCIAPSPDITSLTRIMRLLVRRNIFAVHHPSDGGEPLYGLTHSSRWLLHDAELSLAPILMMNNHPCLMAPWHYFSRRVKEGGPCAFEMAHGLDIWDYASQNPEINKLFNDGMACTSRFELKEILTGYEHGFDGVGSLVDVGGGTGSAVAEIVKAYPNIKGFNFDLPHVVATAPVYHGVSHVGGDMFEGNIPNADAVFMKRIMHDWSDSDCIKILKNCRKAIPEKSGKIIIADIVLEPNGEGTLNDTRLVIDLVMIAHTSGRERTENEWKKILEEGGFPRHKVIKIPALVSIVEAYPM
MGLNNGEVGAISHELLGAQAHVWNHMFQFINSMSLKCAVQLGIPDVIHNHGQPISLSELVARLNIHPSKAHFMSRLMRILVHSDFFAQHDHVHHDRDDAEEEVAVVLYSLTPASGLFLKDGPLNTTPFLLMILDQVITDPFHSMGNWLQMNCGDDLVPCTPFEVANGMPFWELSAKKPRFGDLFNEAMEADSKLIAGVVEECGGVFEGLKSLVDVGGGTGTMAKAIANAFPNINCTVFDQPHVVADLEGMTHNLGFVGGDMFEEIPPANAILLKWILHDWNDEESVKILKKCREAIFLNKNEGRKKKIIIIDIVVGYADNKTKVDKKSIETQLMFDMLMMSTITGKERSESEWEKIFLAAGFSHYNITHMLGLRSLIEVYP
>rna-NM_001328875.1
MSLSNEVGATSHELLGAQAQLWNHIFQFINSMSLKCAVQLGIADVIHNHGQPISLSELMAGLKVHPSKAHFVSRLMRILVHSNFFAQHHHVHHDRADVEEEETVVLYSLTPASRLLLKDGSLNTTPFLLMILDPVVTTPFHLMGAWLKINGGDDPAATCTPFEMENGMPFWELGAREPRFGNLFNEAMEADSKLIGRVVVEECGGVFEGLKSLMDVGGGSGTMAKAIANAFPNINCTVFDQPHVVAGLQGTTHNLGFMGGDMFEEIPPADAILLKWIMHDWNDEESVTILKKCREAISLSKNEGGNKKIIIIDIVVGYVDNKKKMMDKKSIETQLMFDMLMMSILPGKERSKSEWEKIFFAAGFTHYNITHTLGFRSLIEVYP
>rna-XM_008394713.3
MGLSDGEVGSTSHELLEAQAQIWNHMFQFINSMALKCAAQLGIPDVIHNHGQPISLSELIAALNVHPSRAHFVSRLMRILVHSDFFAQHHHVHHDCDDVEEEEAVVLYSLTPTSRLLLKDGPSNTTPLILMILDPVLTTPFHLMGAWLQMNGGDDPATICTPFEMENGMPFWDLAAQEPRFGNLFDEAMEADSKLLGREVVKECGGVFEGLKSLVDVGGGTGTMAKAIANAFPSINCIVFDQPHVVADLQGTTHNLGFVGGDMFVEIPPANAILLKWILHDWSDEESVKILKKCREAILLSKNDEGNKKIIIIDIVVGHVDNKEKMVDKKSIETQLMFDVLMMSAFTGKERSESEWKTIFLAAGFTHYNMTHMFGFRSLIELYP
>rna-XM_029092746.1
MGLSNGEVGATSHELLGAQAQIWNHMFQFINSMALKCAVQLGIPDVIHNHGQPISLSELIAALNVHPSRAHFVSRLMRILVHSDFFAQHHHVHRGCDDMEEEEAVVLYSLTPTSRLLLKDGPSNTTPLILMILDPVLTTPFHLMGAWLQMNGGDDPATICTPFKMENGMPFWDLAAQEPRFGNLFDEAMEADSKLLGREVVEECGGVFEGLKSLVDVGGGTGTMAKAIANAFPSINCIVFDQPHVVANLLGSTHNLGFVGGDMFVEIPPANAILLKWILHDWSDEESVKILKKCREAILLSKNDEGNKKIIIIDIVVGHVDKKEKMVDKKSIETQLMFDMLMMSTVTGKERSESEWKKIFLAAGFTHYNITHTFGFRSLIELYP
>rna-XM_008360216.3
MEEKQRELTWEEEEEGATAEMWKYVFGFTEIAVVRCAIDLGIAEAIENHGSPMTLLELSTALSCDPSHLYRIMRVLVHRKIFKEKPTQSGSNGYAQTPLSRRLLKSAENSMVDLLLMGSNPVMMAPYLRLSTQVQRNTSDAVFDEVHGSDLWNYGAENPDHGKAFNDSMACDARLAVPAALESCPEAFKGIETIVDAGGGNGTTARLLVEACPWITKGIIFDLPHVVSTIPECDRIEKIGGDFFKCIPKADAVVMMWILHDWTDEECISILKNCREAIPNDKGKVIIIDAVVEDNEKDYNKLTRVKLMLDIAMMNGTKGKERTAKEWEYVIREAGFSRHTITPTRTVQSVIQVFP
>rna-XM_008384232.3
MDTQRETEDTKRELTSEEEEERAKVDMWKYVFGFVEIAVVKCAIELGIADAIEIHGSPMTLLELSSALSCDPSHLYRVMRVLVHLKIFKEKTTELGPKGYAQTPLSKRLLKSGENSMAALILLESSPVMLAPWHGLSARLRGNSNPSFEAVHGEDLWSFAAANPDHSKLINDAMACDARVAVPAVIESCLEVFKGLETIVDVGGGDGTTLRLLVETCPWIRGINFDRPHVVSVAHECDRIENVGGDFFYCVPKADAAIIMWVLHDWGDDDCIRILKKCREAIPNDKGKVIIIEAVIEEDGKEDNKLADVRLMLDMVMLAHTNTGKERTFKEWGYVLGEAGFSRYTITPIHAVQSVIQAFP
>rna-XM_029103169.1
MEGDEARDLFGAQSHLYKHVFSFITSMSLKCVVQLGIPDIIDRHGQPITLPDLVTALQIHPAKTGNVHRLMRLMVHSGFFARKQVPKNHVEADEGEEEAYDLTPSSTLLLKDKVPSLSSFVLGMLDPASAAPWQFLGNWFRGTEVTPFESAHGMGFWEYAEGNPEFNSLFNKAMASDSGMMNLVIRDCKPIFDGLSSLVDVGGGTGKVARILCDAFPQLKCTVLELPHVVADLPDCENLKFVRGDMFQGIPPADAVFLKLILHDLSDEECLKVLKKCREAIASNGQGKVIIIDIVMNEEKDEHEITEAKLLFDLLMMVVITGRERSEKDWKKLFLEAGFSSYKVTPIFGLRSLIEVFL
>rna-XM_029102218.1
MEDNQSVLTWEEEEEHVKVDVWKYVFGFVEIVVIKCAIELGIAEAIETRGSPMTLLELSSALRCDPSHIYRIMRVLVHLKIFKEQTTIQLGSKSYAQTPLSRLLLKSGENSMAELILLESSPTMLAPWHSLSSRVQGNLRNPVFEELHGKDLWSFGVANPDHNKLFNEAMACDARLAVPALVKSCVKVFKGVGTLVDVGGGNETTLRLLVEACPWIQGINFDLPHVVSDAQKPDRIEYVGGNMFDCVPKADAIIIKWVLHDWGDDDCIRILKKCREAIPIDKGKVIIVEAVIDEKDEKANSKLKKARLMLDMVMIAHTGTGKERTMEEWEYVLGEAGFSRHTITPIHTIQSVIQAFP
>rna-XM_008360210.3
MEDTQRVLTWEEEEEHAKVDVWKYVFGFVEIAVVKCAIELGIAEAIESHGSPMTLLELSSALSCDPSHLYRVMRVLVHLKLFKEITTNQLGSKGYAQTPLSHRLLKSGENSMVALILLESSPVMLAPWHGLSARIRGNISNQLFEEVHGEDLWSFGAANPDHSKLFNDAMTCDVKAAVPAVIKSCIEVFKGLETIVDVGGGNGTMLRLLVEGCPWIRGINFDLPHVVSAAQDCDRVENVGGDMFDRVPKADAVIIKGVLHNWGDDDCIRILKKCREAVPKDTGKVIIIDAVIDEKYEKEDKKLANLKLMLDMVMIAHTNKGKERSLKEWEYVLGGAGFSGHTITPVPAIQYSVIQAFP
>rna-XM_029107936.1
MEMQEATEVEASLRGQADIWKYMLGFADSMALKCAVELRIADIIHSHSPTDGASNSKPMITLSQVASSIAPSPDMTYLTRIMRLLVRRNIFAIHHPSDGGTLYGLTHSSRWLLHNAELSLAPMLMMENHPCLMAPWHYFGQCVKEGGPYAFKMAHGLEIWDYASQNPEFNKLFNDGMACTTRVVMKAILTGYEHGFDGVGSLVDVGGGTGSAVAEIVKSYPNIKGFNFDLPHVVATAPVYHGVSHVSGDMFEGSIPNADAVFMKRIMHNWSDNDCIKILKNCRKAIPEKSGKIIIVDIVLEPNGEGILDDTRLVFDLLMIAHASGGRERTETEWKNILEEGGFPRYKVIKIPALASIVEAYPM
>rna-XM_008367216.3
MEMQEATEVEASLRGQADIWKYMFGFADSMALKCAVELRIADIIHSHSPTDGASNSRPMITLSQLASSIAPSPDMTYLTRIMRLLVRRNIFAIHHSSDGEEPLYGLTHSSRWLLHNTELSLAPMLVMENHPCLMAPWHYFSQCVKEGGPYAFKMAHGLEIWDYASQNPEFNKLFNDGMACTARVVMKAILTGYEHGFDGVGSLVDVGGGTGSAVAEIVKSYPNIKGFNFDLPHVVATAPVYHGVSHVGGDMFEGSIPNADAVFMKWIMHDWSDSDCIKILKNCRKAIPEKSGKIIIVDIVLEPNGEGILDDTRLVFDLLMIAHTSGGRERTETEWKNILEEGGFPRYKVIKIPALASIVEAYPM
>rna-XM_008359596.3
MQEEPEIEASLRGQADIWKYMFGFADSMALKCAVELRIADIIHSHRPSDGASNSNPMIALSQLASCIAPSPDITSLTRIMRLLVRRNIFAVHHPSDGGEPLYGLTHSSRWLLHDAELSLAPILMMNNHPCLMAPWHYFSRRVKEGGPCAFEMAHGLDIWDYASQNPEINKLFNDGMACTSRFELKEILTGYEHGFDGVGSLVDVGGGTGSAVAEIVKAYPNIKGFNFDLPHVVATAPVYHGVSHVGGDMFEGNIPNADAVFMKRIMHDWSDSDCIKILKNCRKAIPEKSGKIIIADIVLEPNGEGTLNDTRLVIDLVMIAHTSGRERTENEWKKILEEGGFPRHKVIKIPALVSIVEAYPM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University