Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Amphicarpaea edgeworthi
Species name
Chinese hog-peanut (Amphicarpaea edgeworthii) is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Amphicarpaea_edgeworthi.ROMT.fa
Download
>Ae.00008394
MESSVGDHGAKVLQAQTHVWNHTLNFINSMSIKCIIDLGIPDVIHDYGKPMPLSSLIASLPIHPSKTQFIHRLMRIMVYSGFFSQHNNDNNVTATENELEKVEYALTDASTLLLKNHPMSVAPLLHANLDASVMSLLGHRFSNWFKNDDHTPFEITHGMTFWDYVGHDPKVNNLFNDAMANDTRLVTSLVIEKCKEVFKGLESLVDVGGGTGTMAKVIANSFPQMQCTVYDLPQVVGKLQGSENLKYVGGDMFESIPPADAILLKWVLHDWSDEKCLNILKNCKEAITKEGKKGKVVIIDMVVDDEKRDDESVETQLLFDVLMMVLYNGKERNKKEWVKLISSAGFSDYKITPAVFGLRSLIEIYP
>Ae.00008344
MESHVGDHSMKVLHQAQTHVWNHILSFINSMSLKCLVGLGIPDVINDYGQPMPLSNLIASLPIYPSKTQCIHRLMRIMVHSGFFSQQNNVTCENELEEVKYALTDASTLLLCLRTIP
>Ae.00008056
MESNVVEHGANKVLQAHAHVWNHGLSFINYMSIKCVVELGIPDIIHDYAKPMPLSSLIASLPIHPSKTHFIHRLMRVTTHYGFFSQQNVTENELEVEVEYALTDASRLLLKNHPMSVAPLMHASLDASVMSLQGHRFSNWFKNDDHTPFETTHGMTFWDYVGHDPKVNNLFNDAMVNDTRLVTSLVVEKCKEVFTGLESLVDVGGGTGTMAKVIANSFPQMQCTVYDLPQVVGNLQGSENLKYVGGDMFESIPPADAILLKWVLHNWSDEKCLNILKNCKEAITKEGKKGKVVIIDMVVDDEKRDDESVETQLLFDVLMMVLFNGKERNKKEWVKLISSAGFSDYKITPAVFGLRSLIEIYP
>Ae.00007731
MQCIVLDLPHVVAGLHGSENLKYFGGDMFESILHDWNGEECMNILKKCKEAIMRKGKKGKVIIIDMVMDDEKRDNESVETQLLFDMQMMVLVTGKERNKKEWVKLISSTGFSDYKITPTIFGLRSLIEIYP
>Ae.00007780
HTRYHTRLWQTHAILKPHCFTTIHPSKTQFIHRLMRIMVYSGFFSQHNNSNNVTDTENELEKVEYALTDASKLLLRNHPMSVAPLLHAFIDPSFVSILLGHRFSNWFKNDDPTPFETARGMTFWDYVGSDSKLKNLFNDGMASDVRLVSTFLIDKCRGVFLGLESLVDVGGGTGNIAKVIANAFPHMQCTVFDLPHVVGDLQGSENLKYVGGDMFETIPPADAILLKWILHDWSDEKCLNILKKCKEAITKGGKKGKVIIIDMVVDDEKRDDVSVETQLLFDVSMMVLFTGKERNKKEWVKLISSAGFIDYKITPAVFGVRSLIEIYP
>Ae.00007781
MESLDEEHAAKLLRAQTHIWNHIFSFINSMSLKCVVELGIPDIIHNYGQPMPLSNLIASLSIHQSKTHFIHRLMRIMVHSGFFSQQENELEEVKYVLTDASLLLLKNDPMSVTPFLLGMLDPILTNPWNQFSTWFKNGDPTPFETTHGMTLWGYAGADPKLNNLFNDAMASDARLVTSLVIEKCKGVFMGLESLVDVGGGTGTMAKAIAKSFPHMQCIAFDLPHVVSVLEPSENLKFVGGDMFEAIPPADAILLKWILHDWNDEECVNILKKCKEAIKGKGKEGKVIIIDIVVENDEKRDDESIETQLFFDMLMMVLVTGKERHKKEWAKLISSAGYNSYKITHVLGLRSIIEIYP
>Ae.00019427
MESHSEEMNATKLVEAQTHVWNHIFQFINSFSLKCAVDLSIPDIIHNYGQPMPLSKLIASLPIHPSKTCFIYRLMRILTHSGFFNQSHNNVVTKNDVQEVRYVLTDASRLLLLKDDQSLMSTIASLVQALTDPINVNPWNQLSTWFTNEDPTPFQTQHGMTFWDLTARDHRFNNLFNDAMASDTQLVSSVVIEKCKGVFEGSESLVDVGGGTGTMAMAIAKSFPQLKCIVFDLPQVVADLQGTENIKYWVLHNWNDEECVKILNNCKDALTSDGTVIIIDLVMENNKKEEDHKLIETQLFFDMQMMMVVTGKERNQKEWAKLIFSAGWVTTHGRTGMEKELGMMVQMGERERIVGVGLGLGC
>Ae.00019158
MDFDNEDHYAKLLRAQTHIFHHTFGFINSMSLKCAIDLCIPDIIHNYGKPMPLSQLIASLQIHPSKTCFLPRLMQILTHSGFFNQHNVVKENEHEVSYVLTDASRLLLKDHPFSMISIPQVILDPILVNPWFQFSNWFTNEDPTPFHTQHGMSFWDYASTEPKLNHLFNDAMTNDSRLVSSVVIEKCKGVFDGLESLVDVGGGTGAMAKAIAKSFPQLKCIVFDLPHVVHGLHGMENITYVEGDMFEAIPSSDSIMLKKCKEAITNKDKGKVIIIDVVIENKEKAHNELDQTKLFYDIEMMVLVTGKERNEKDWAKLFFSAGFNNYKITPVPGFKSLIEVYP
>Ae.00018664
MEYFDNEDRSSKLLQAQTHILNLSFSFIKSMSLKCAIDLCIPDVLHSPLDANFDSFSQHNVVIENEHEVSYVLTDASTLLLNDHPLCMTSLMRFNFDPIIINPFHQFSTWFKNEDPTLFQTQHGMTFWDFVRHEPKFNHIFNDAMASDSRLVSNVVIEKCKGGLESLVDVGGGTGTMAKAIANSFPQMKCIVFDLPHVVHDLHGTKNIAYVGGDMFEAIPSADSIMLKWILHDWKDEECSKILKKCKEAIAGKDKGKVLIIDVVIGNEKGDNELDETKLFYDIEMMALLAAKERNEKDWAKLFFSAGFIELYP
>Ae.00018330
MEHEQSEDRVSKLLGAQTHVWNHIFSFINSMSLKCAIELNIPDIIHNHGQPMPLSKLTTSLSIHPSKANNIYRLMRILTHSGFFSQHKVNDNNLEIGYTLTDASTLLLKDNPLSMAPFLHAMLDPILTQPWLKLPTWFRNDDPSPFQTAHGVKIWDYADREPKLNELFNDAMASDTQLVANVVVERCKGVFKGLESLVDVGGGTGTMAKAIADTFPQLECTVFDLPHVVATLQGSNNLKYVGGDMFESIPIADAALLKWILHDWNDEQCVKILEKCKETIKSKVIVIDMVVENENRDHEAIETQLFIDMVVMVLYPGKERTEKEWAKLIFTAGFSDYKITPVLGLRSLIEIYP
>Ae.00018325
MESHSEENVTKLLQAQTHVWNHIFKFINSLSLKCAIELSIPDIIRKYGQPMPLSKLIASLPIQPTKTCFIYRLMRILTHSGFFFEDNEQEEMSYVLTDASKLLLKDHHSSMTSLLQVIVDPIYINPWYQFTTWLTNEDPTPFHTQNGMPFWEFAGCDPKFNHLFNDAMASDTQWVSSVVIEKCKEMFNRSESLVDVGGGTGTMAKAIAKSFPQLKCIVFDLPHVVAGLQGTENIKYVGGDMFQEAIPSADSIMLKWVLHNWNDEESVKILNKCKEARSSDEGRVIIIDLVMKNEKEDDKLIETQMFFDMQMMVAQWKRKKRERMGQAVSLCWFQ
MESSVGDHGAKVLQAQTHVWNHTLNFINSMSIKCIIDLGIPDVIHDYGKPMPLSSLIASLPIHPSKTQFIHRLMRIMVYSGFFSQHNNDNNVTATENELEKVEYALTDASTLLLKNHPMSVAPLLHANLDASVMSLLGHRFSNWFKNDDHTPFEITHGMTFWDYVGHDPKVNNLFNDAMANDTRLVTSLVIEKCKEVFKGLESLVDVGGGTGTMAKVIANSFPQMQCTVYDLPQVVGKLQGSENLKYVGGDMFESIPPADAILLKWVLHDWSDEKCLNILKNCKEAITKEGKKGKVVIIDMVVDDEKRDDESVETQLLFDVLMMVLYNGKERNKKEWVKLISSAGFSDYKITPAVFGLRSLIEIYP
>Ae.00008344
MESHVGDHSMKVLHQAQTHVWNHILSFINSMSLKCLVGLGIPDVINDYGQPMPLSNLIASLPIYPSKTQCIHRLMRIMVHSGFFSQQNNVTCENELEEVKYALTDASTLLLCLRTIP
>Ae.00008056
MESNVVEHGANKVLQAHAHVWNHGLSFINYMSIKCVVELGIPDIIHDYAKPMPLSSLIASLPIHPSKTHFIHRLMRVTTHYGFFSQQNVTENELEVEVEYALTDASRLLLKNHPMSVAPLMHASLDASVMSLQGHRFSNWFKNDDHTPFETTHGMTFWDYVGHDPKVNNLFNDAMVNDTRLVTSLVVEKCKEVFTGLESLVDVGGGTGTMAKVIANSFPQMQCTVYDLPQVVGNLQGSENLKYVGGDMFESIPPADAILLKWVLHNWSDEKCLNILKNCKEAITKEGKKGKVVIIDMVVDDEKRDDESVETQLLFDVLMMVLFNGKERNKKEWVKLISSAGFSDYKITPAVFGLRSLIEIYP
>Ae.00007731
MQCIVLDLPHVVAGLHGSENLKYFGGDMFESILHDWNGEECMNILKKCKEAIMRKGKKGKVIIIDMVMDDEKRDNESVETQLLFDMQMMVLVTGKERNKKEWVKLISSTGFSDYKITPTIFGLRSLIEIYP
>Ae.00007780
HTRYHTRLWQTHAILKPHCFTTIHPSKTQFIHRLMRIMVYSGFFSQHNNSNNVTDTENELEKVEYALTDASKLLLRNHPMSVAPLLHAFIDPSFVSILLGHRFSNWFKNDDPTPFETARGMTFWDYVGSDSKLKNLFNDGMASDVRLVSTFLIDKCRGVFLGLESLVDVGGGTGNIAKVIANAFPHMQCTVFDLPHVVGDLQGSENLKYVGGDMFETIPPADAILLKWILHDWSDEKCLNILKKCKEAITKGGKKGKVIIIDMVVDDEKRDDVSVETQLLFDVSMMVLFTGKERNKKEWVKLISSAGFIDYKITPAVFGVRSLIEIYP
>Ae.00007781
MESLDEEHAAKLLRAQTHIWNHIFSFINSMSLKCVVELGIPDIIHNYGQPMPLSNLIASLSIHQSKTHFIHRLMRIMVHSGFFSQQENELEEVKYVLTDASLLLLKNDPMSVTPFLLGMLDPILTNPWNQFSTWFKNGDPTPFETTHGMTLWGYAGADPKLNNLFNDAMASDARLVTSLVIEKCKGVFMGLESLVDVGGGTGTMAKAIAKSFPHMQCIAFDLPHVVSVLEPSENLKFVGGDMFEAIPPADAILLKWILHDWNDEECVNILKKCKEAIKGKGKEGKVIIIDIVVENDEKRDDESIETQLFFDMLMMVLVTGKERHKKEWAKLISSAGYNSYKITHVLGLRSIIEIYP
>Ae.00019427
MESHSEEMNATKLVEAQTHVWNHIFQFINSFSLKCAVDLSIPDIIHNYGQPMPLSKLIASLPIHPSKTCFIYRLMRILTHSGFFNQSHNNVVTKNDVQEVRYVLTDASRLLLLKDDQSLMSTIASLVQALTDPINVNPWNQLSTWFTNEDPTPFQTQHGMTFWDLTARDHRFNNLFNDAMASDTQLVSSVVIEKCKGVFEGSESLVDVGGGTGTMAMAIAKSFPQLKCIVFDLPQVVADLQGTENIKYWVLHNWNDEECVKILNNCKDALTSDGTVIIIDLVMENNKKEEDHKLIETQLFFDMQMMMVVTGKERNQKEWAKLIFSAGWVTTHGRTGMEKELGMMVQMGERERIVGVGLGLGC
>Ae.00019158
MDFDNEDHYAKLLRAQTHIFHHTFGFINSMSLKCAIDLCIPDIIHNYGKPMPLSQLIASLQIHPSKTCFLPRLMQILTHSGFFNQHNVVKENEHEVSYVLTDASRLLLKDHPFSMISIPQVILDPILVNPWFQFSNWFTNEDPTPFHTQHGMSFWDYASTEPKLNHLFNDAMTNDSRLVSSVVIEKCKGVFDGLESLVDVGGGTGAMAKAIAKSFPQLKCIVFDLPHVVHGLHGMENITYVEGDMFEAIPSSDSIMLKKCKEAITNKDKGKVIIIDVVIENKEKAHNELDQTKLFYDIEMMVLVTGKERNEKDWAKLFFSAGFNNYKITPVPGFKSLIEVYP
>Ae.00018664
MEYFDNEDRSSKLLQAQTHILNLSFSFIKSMSLKCAIDLCIPDVLHSPLDANFDSFSQHNVVIENEHEVSYVLTDASTLLLNDHPLCMTSLMRFNFDPIIINPFHQFSTWFKNEDPTLFQTQHGMTFWDFVRHEPKFNHIFNDAMASDSRLVSNVVIEKCKGGLESLVDVGGGTGTMAKAIANSFPQMKCIVFDLPHVVHDLHGTKNIAYVGGDMFEAIPSADSIMLKWILHDWKDEECSKILKKCKEAIAGKDKGKVLIIDVVIGNEKGDNELDETKLFYDIEMMALLAAKERNEKDWAKLFFSAGFIELYP
>Ae.00018330
MEHEQSEDRVSKLLGAQTHVWNHIFSFINSMSLKCAIELNIPDIIHNHGQPMPLSKLTTSLSIHPSKANNIYRLMRILTHSGFFSQHKVNDNNLEIGYTLTDASTLLLKDNPLSMAPFLHAMLDPILTQPWLKLPTWFRNDDPSPFQTAHGVKIWDYADREPKLNELFNDAMASDTQLVANVVVERCKGVFKGLESLVDVGGGTGTMAKAIADTFPQLECTVFDLPHVVATLQGSNNLKYVGGDMFESIPIADAALLKWILHDWNDEQCVKILEKCKETIKSKVIVIDMVVENENRDHEAIETQLFIDMVVMVLYPGKERTEKEWAKLIFTAGFSDYKITPVLGLRSLIEIYP
>Ae.00018325
MESHSEENVTKLLQAQTHVWNHIFKFINSLSLKCAIELSIPDIIRKYGQPMPLSKLIASLPIQPTKTCFIYRLMRILTHSGFFFEDNEQEEMSYVLTDASKLLLKDHHSSMTSLLQVIVDPIYINPWYQFTTWLTNEDPTPFHTQNGMPFWEFAGCDPKFNHLFNDAMASDTQWVSSVVIEKCKEMFNRSESLVDVGGGTGTMAKAIAKSFPQLKCIVFDLPHVVAGLQGTENIKYVGGDMFQEAIPSADSIMLKWVLHNWNDEESVKILNKCKEARSSDEGRVIIIDLVMKNEKEDDKLIETQMFFDMQMMVAQWKRKKRERMGQAVSLCWFQ
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University