Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Malcolmia maritima
Species name
Malcolmia maritima is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Malcolmia_maritima.4CL.fa
Download
>Mamar.0029s0969.1.v1.1
MVLQQQETHFLTKNQEQVEPSQDFIFRSKLPDIFIPNHLPLIDYVFQRFSGEAHGDGDSTTCLIDGATGRILTYADVLTNTRRIAAGIHRLGIGHGDVVMLLLPNSPEFALSFLAVAYLGAVSTTANPFYTQPEITKQAKDSAAKMIVTKRCYVDKITNLKNDGVLIVCVEDESDDDVVDGCVSFTELTQADETELPKPVISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLNFTADDVILCFLPMFHIYALDALMLSAMRTGASLLIVPRFELNLVMELIQRHKVTVVPVAPPVVLAFIKSPETERYDLSSVRIMLSGAATLKKELEEAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTITGISLPRNKAGEICVRGDQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEVFIVDRLKELIKFKGYQVAPAELEALLISHPSIDDAAVVGVKDEVADEVPVAFVVRSEGSQLTEDDVKSYVNKQVVHYKRIKMVFFIEAIPKAVSGKILRKDLRAKVETECSK
>Mamar.0029s0970.1.v1.1
MSTQEAIFTDQKQSSSDDVIFRSKLPDIYIPNHLPLHDYIFENISEFADKPCLINGPTGEVYTYADVKAKSRKIAAGLQKLGVNQHDVVMLLLQNSPEVVLTFLAVSFLGAATTAANPFFTPAEITKQAKASAAKLIVTHSQYVGKIKNLQNDGVLIVTTDDVIPEGCLSFSDLVNSEDILNSPPEISQDDVVALPFSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYFHKEDVILCVLPMFHIYALNSIMLCSLRVGATILIMPKFEITLLLEQIQRCKVTVAMVVPPIVLAIVKSPETEKYDLSSVRIIKSGAAPLGKELEDAISVKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIIDPDTGDSLPRNKSGEICIRGHQVMKGYLNDPAATASTIDKDGWLHTGDVGFIDEDDELFIVDRLKEIIKYKGFQVAPAELESLLIAHQEINDVAVVAMKEEDAGEVPVAFVVRSKDSKISEDEIKQFVSKQVVFYKRISKVFFTDSIPKAPSGKILRKDLRARLASGSMN
>Mamar.0046s0085.1.v1.1
MEKSGYGRDGIYRSLRPTLVLPKDPNTSLVSFLFRNSSSYPSKLAIADSDSGDSLTFSQLKSAVARLAHGFHRLGIRKNDAVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVNEVSKQIKDSNPKIIISVNQLFDKIKGFDLPIVLLGSGDSVKIPQGSNSKILSFNDVMELSEPVSDFPVVEIKQSDTASLLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLTVITYSQLQRGNALVSMAKFDLEMMLKNIEKYRVTQLWVVPPVFLALAKQSIVKKFDLSSLKYIGSGAAPLGKDLMEECGRNIPNVLLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETGKPQPPNQLGEIWVRGPNMMKGYYNNPQATKETIDKKGWVHTGDLGYFNEDGNLYVVDRIKELIKYKGFQVAPAELEDLLVSHPEILDAGVIPFPDEEAGEVPIAFVVRSPNSTITEEAIQKFIAKQVAPFKRLRRVSFINTIPKSAAGKILRRELVQQVRSKM
>Mamar.0052s0893.1.v1.1
MAPQQEVMEKQSSNNNTDVIFRSKLPDIYIPNHLSLHDYIFQNLSEFASKPCLINGPTGHVYTYSDVHVISRRIAAGFHKLGVNQNDVVMLLLPNCPEFVLSFLAASFRGAIATAANPFFTPAEIAKQAKASNSKLIVTESRYVDKIKSLQNDDGVVIVCIDDNESVPIPEGCLRFTELTQPSTESTDVIDSVVISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPMVPPIVLAIAKSPETEKYDLSSIRVVKSGAAPLGKELEDAVSAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSELSEDDVKQFVSKQVVFYKRINKVFFTETIPKAPSGKILRKDLRAKLANGL
>Mamar.0055s0170.1.v1.1
MESQKQDNEHIFRSLYPSVPIPDKLTLPEFVLQGVDEYTENVAFVEAVTGKAVTYGDVVRDTKRLAKALTSLGLKKGQVMVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEVSGARGIITDATNYEKVKTLGLPVIVLGEEKIEGAVNWRDLLEAGDRSGDNENEEEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSTLFSVRSEMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRYDLRIFLNALIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLSAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSVGFILPNLEVKFIDPETSRSLPKNTPGELCVRSQCVMQGYFMNKEETDKTIDEQGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSIEDVAVVPLPDEEAGEIPAACVVINPKATEKEEDILNFVAANVAHYKKVRAVHFVDSIPKSLSGKIMRRLLRDKILSIHNNK
>Mamar.0058s0150.1.v1.1
MAATHLHITPNAKTQTSPQNLPFWFSPKTGIYTSKFPSIHLPVDPNLDAVSVLFSHTHLNVDSAALVDSLTGFSISHTELQIMVQSIAAGVYHDLGVRQGDVVSLVLPNSVYFPLIFLSLISLGAIVTTMNPSSSLGEIKKQVSECNVGLAFTSTENVDKLSSLGVMVIRVPESYDFDLIRIENPKFYSIFKGGFRFVPKPLIRQDDVAAIMYSSGTTGASKGVFLTHRNLIATMELFVRFEASQYEYPGSSNVYLAALPLCHIYGLSLFVLGLLSLGSTIVVMRRFDASDVINVIERFKVTHLPVVPPMLMALTKKAKGVCGEVFKSLKQVSSGAAPLSGKFIEDFLQTLPHVDLIQGYGMTESTAVGTRGFNSEKLSRYSSVGLLAPNMQAKVVDWSSGSFLPPGKRGELWIQGPGVMKGYLNNPKATQMTIVEDSWLRTGDIAYFDEDGYLFIVDRIKEIIKYKGFQIAPADLEAVLVSHPSIIDAAVTAAPNEECGEIPVAFVVRRQDTTLSEQDVISYVASQVAPYRKVRKVVMVSSIPKSPAGKILRKELKRLLTNSVSSRL
>Mamar.0078s0017.1.v1.1
MITAALHEPQIHKPTDTSPPAVISGDVLPPPPPPTPRIFRSKLPDIDIPNHLPLHTYCFDKLSSVSDKPCLIVGSTGKSYTYDETHLICRKVASGLYKIGIKKGDVIMILLQNSPEFVFSFMGASMIGAVSTTANPFYTSQEIYKQLKSSGAKLIITHSHYVDKLRNLDETRIGENLIVITTDDPTPENCLPFSTLITDDTNPFQESVNIGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNLYLKSNDVVLCVLPLFHIYSLNSVLLNSIRAGATVLLMHKFEISALLDLIQRHRVTIAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKELQDSLRRRLPQAILGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLETRISLGYNQPGEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHHSIADAAVVPQNDEVAGEVPVAFVVRSNGNDITEEDIKEYISKQVVFYKRLHKVFFVPSIPKSPSGKILRKDLKAKLC
MVLQQQETHFLTKNQEQVEPSQDFIFRSKLPDIFIPNHLPLIDYVFQRFSGEAHGDGDSTTCLIDGATGRILTYADVLTNTRRIAAGIHRLGIGHGDVVMLLLPNSPEFALSFLAVAYLGAVSTTANPFYTQPEITKQAKDSAAKMIVTKRCYVDKITNLKNDGVLIVCVEDESDDDVVDGCVSFTELTQADETELPKPVISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLNFTADDVILCFLPMFHIYALDALMLSAMRTGASLLIVPRFELNLVMELIQRHKVTVVPVAPPVVLAFIKSPETERYDLSSVRIMLSGAATLKKELEEAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTITGISLPRNKAGEICVRGDQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEVFIVDRLKELIKFKGYQVAPAELEALLISHPSIDDAAVVGVKDEVADEVPVAFVVRSEGSQLTEDDVKSYVNKQVVHYKRIKMVFFIEAIPKAVSGKILRKDLRAKVETECSK
>Mamar.0029s0970.1.v1.1
MSTQEAIFTDQKQSSSDDVIFRSKLPDIYIPNHLPLHDYIFENISEFADKPCLINGPTGEVYTYADVKAKSRKIAAGLQKLGVNQHDVVMLLLQNSPEVVLTFLAVSFLGAATTAANPFFTPAEITKQAKASAAKLIVTHSQYVGKIKNLQNDGVLIVTTDDVIPEGCLSFSDLVNSEDILNSPPEISQDDVVALPFSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYFHKEDVILCVLPMFHIYALNSIMLCSLRVGATILIMPKFEITLLLEQIQRCKVTVAMVVPPIVLAIVKSPETEKYDLSSVRIIKSGAAPLGKELEDAISVKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIIDPDTGDSLPRNKSGEICIRGHQVMKGYLNDPAATASTIDKDGWLHTGDVGFIDEDDELFIVDRLKEIIKYKGFQVAPAELESLLIAHQEINDVAVVAMKEEDAGEVPVAFVVRSKDSKISEDEIKQFVSKQVVFYKRISKVFFTDSIPKAPSGKILRKDLRARLASGSMN
>Mamar.0046s0085.1.v1.1
MEKSGYGRDGIYRSLRPTLVLPKDPNTSLVSFLFRNSSSYPSKLAIADSDSGDSLTFSQLKSAVARLAHGFHRLGIRKNDAVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVNEVSKQIKDSNPKIIISVNQLFDKIKGFDLPIVLLGSGDSVKIPQGSNSKILSFNDVMELSEPVSDFPVVEIKQSDTASLLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLTVITYSQLQRGNALVSMAKFDLEMMLKNIEKYRVTQLWVVPPVFLALAKQSIVKKFDLSSLKYIGSGAAPLGKDLMEECGRNIPNVLLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETGKPQPPNQLGEIWVRGPNMMKGYYNNPQATKETIDKKGWVHTGDLGYFNEDGNLYVVDRIKELIKYKGFQVAPAELEDLLVSHPEILDAGVIPFPDEEAGEVPIAFVVRSPNSTITEEAIQKFIAKQVAPFKRLRRVSFINTIPKSAAGKILRRELVQQVRSKM
>Mamar.0052s0893.1.v1.1
MAPQQEVMEKQSSNNNTDVIFRSKLPDIYIPNHLSLHDYIFQNLSEFASKPCLINGPTGHVYTYSDVHVISRRIAAGFHKLGVNQNDVVMLLLPNCPEFVLSFLAASFRGAIATAANPFFTPAEIAKQAKASNSKLIVTESRYVDKIKSLQNDDGVVIVCIDDNESVPIPEGCLRFTELTQPSTESTDVIDSVVISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPMVPPIVLAIAKSPETEKYDLSSIRVVKSGAAPLGKELEDAVSAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSELSEDDVKQFVSKQVVFYKRINKVFFTETIPKAPSGKILRKDLRAKLANGL
>Mamar.0055s0170.1.v1.1
MESQKQDNEHIFRSLYPSVPIPDKLTLPEFVLQGVDEYTENVAFVEAVTGKAVTYGDVVRDTKRLAKALTSLGLKKGQVMVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEVSGARGIITDATNYEKVKTLGLPVIVLGEEKIEGAVNWRDLLEAGDRSGDNENEEEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSTLFSVRSEMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRYDLRIFLNALIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLSAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSVGFILPNLEVKFIDPETSRSLPKNTPGELCVRSQCVMQGYFMNKEETDKTIDEQGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSIEDVAVVPLPDEEAGEIPAACVVINPKATEKEEDILNFVAANVAHYKKVRAVHFVDSIPKSLSGKIMRRLLRDKILSIHNNK
>Mamar.0058s0150.1.v1.1
MAATHLHITPNAKTQTSPQNLPFWFSPKTGIYTSKFPSIHLPVDPNLDAVSVLFSHTHLNVDSAALVDSLTGFSISHTELQIMVQSIAAGVYHDLGVRQGDVVSLVLPNSVYFPLIFLSLISLGAIVTTMNPSSSLGEIKKQVSECNVGLAFTSTENVDKLSSLGVMVIRVPESYDFDLIRIENPKFYSIFKGGFRFVPKPLIRQDDVAAIMYSSGTTGASKGVFLTHRNLIATMELFVRFEASQYEYPGSSNVYLAALPLCHIYGLSLFVLGLLSLGSTIVVMRRFDASDVINVIERFKVTHLPVVPPMLMALTKKAKGVCGEVFKSLKQVSSGAAPLSGKFIEDFLQTLPHVDLIQGYGMTESTAVGTRGFNSEKLSRYSSVGLLAPNMQAKVVDWSSGSFLPPGKRGELWIQGPGVMKGYLNNPKATQMTIVEDSWLRTGDIAYFDEDGYLFIVDRIKEIIKYKGFQIAPADLEAVLVSHPSIIDAAVTAAPNEECGEIPVAFVVRRQDTTLSEQDVISYVASQVAPYRKVRKVVMVSSIPKSPAGKILRKELKRLLTNSVSSRL
>Mamar.0078s0017.1.v1.1
MITAALHEPQIHKPTDTSPPAVISGDVLPPPPPPTPRIFRSKLPDIDIPNHLPLHTYCFDKLSSVSDKPCLIVGSTGKSYTYDETHLICRKVASGLYKIGIKKGDVIMILLQNSPEFVFSFMGASMIGAVSTTANPFYTSQEIYKQLKSSGAKLIITHSHYVDKLRNLDETRIGENLIVITTDDPTPENCLPFSTLITDDTNPFQESVNIGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNLYLKSNDVVLCVLPLFHIYSLNSVLLNSIRAGATVLLMHKFEISALLDLIQRHRVTIAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKELQDSLRRRLPQAILGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLETRISLGYNQPGEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHHSIADAAVVPQNDEVAGEVPVAFVVRSNGNDITEEDIKEYISKQVVFYKRLHKVFFVPSIPKSPSGKILRKDLKAKLC
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University