Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Malania oleifera
Species name
Malania oleifera is a species of eudicot in the family Ximeniaceae.
Species info
Gene sequence info
Malania_oleifera.4CL.fa
Download
>Maole_017307.T1
MAKSCYGEDGIYRSLRPPLNLPPNPNTSMVDFLFQNSSSFPNSTALIDHDSGEILTFCRLKSVVCNLSHALSRLGIRRNDVVLIFAPNSIYFPICFLATVALGAIASTINPSYTVREISRQVKDCNPKLVVTVPELWDKVKQFDLLYLFIKPPISVNCSIRSDCKTWHLFDLINKLDQASDLPEVSVAQGDAAALLYSSGTTGTSKGVILTHRNFIAGALMVTADQELYGERDNVFLCFLPMFHVLALSLIVYAQLQRGNAVVSMAMEKFEMEKVLGAVEKFRVTHLYVVPPVMVALAKQSAVKNYDLSSLKILGTGAAPLGKDVMEECAKVLPQADVMQGYGMTETCGVVSMEDPKTRSCLSGSTGTLLTGVESQIVSVDTLKPIPPNELGEIWFRGPNMMKGYLNNPQATKLTIDEQGWVHSGDLGYFDEKGELYVVDRIKELIKCNGFQVAPAELEGLLLAHPEILDAIVIPFPDARAGEVPIAYVVRSPNSLLTEADVQNFIADQASTRCGGNVATCHVVGEWGMHAYTKKRAAVIASDKGNADYCCNGLILGFEFVGLGVMVFGSVRLKVSGVGSLLLLEWMATAVAAGVLRWLCEAVGVTGCCGVLCSAVEEWLGLVWLEVWSGAAVGAEGWQWSVAESCEALPELQKAADWFSAATDGVWQQDGRRGRVDSPEMLVGGLARARLAGEFSHGIVMQKNGNRNGIKLVIVGEQVAGMHELVVAMHALGAPPLPSIL
>Maole_021020.T1
METETKQSEIIFRSKLPDIPIPNHLPLHAYCFENISEVASRPCLIYGPTGKTYTYEEVELTARRVASGLHRLGIRQGDVIMLLLPNSPEFIFAFLGASYRGAITTGANPFHTRSEIVKHARAAKARLIITQAANFEKVKGLGDELGVKMMCVDGAPPEGWLKFSELTESDEREMPEVEIGADDVVALPFSSGTTGLPKGVMLTHKGNVTSVAQQVDGENPNLYLRREDVILCVLPLFHIYSLNIMLCALRVGAAVAIMPKFDIVSLLELVEKYKVTVAPFVPPIVLAIAKSGEVDRYDLRSVRMVKSGAAPLGKELEDAIKAKFPNAKFGQRYLNQRNVFSLK
>Maole_010609.T1
MAVNRAKKGGSGRRLGKGFNRGCELARALTKPNMSGEKGEEGWEQRETRKEKAGSSKRLEKRIDGERESARAPMKLAFYLRGMQTAHGPYYAWPMREFKASRAAPTYSRPDLFAASSKHAWSIASFHIVSDRHFDSLHAAPSYSIFLRAELHNLNIQLPSPSPSPTESRLLHDIYGEVRLWPRWHSSYPHKLALADAHSGESLTFAQLKSMVARVSHGLTQLGIKKGDVVLILSPNSIKFALCFFGIVAIGAVATTANPSFTVSELSKQVKDSNPKLVITIPELWEKVKGFRLPVVILESQGSSNSIVSKSDRIAFFSELIGISGPAPDLPRASAKQTDTAVLLYSSGTTGNSKGVILTHRNFISASLMSASDQDFAGEMHNVFVCLVPMFHVFGLALILYSQLQRGNAVVSVPKFELEMLLRAVEKYRVTNLWVVPPIILALAKQRELLRKYDLSSLKQVGSGAAPLGKDLMEDCAKSIPQAMVLQVRLLQTGY
>Maole_010608.T1
MTETCGIIALENPMIGGRHSGSTGMLSPGIEAQIVSVEKLKPLPPNQLGEIWVRGPNMMQGYLNNPQATKQAIDKKGWVHTGDLGYFDDVGRLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEIVDAVVIPFPDAEAGEIPVAYVVRSPNSSLTEEEIQTFISNQVAPFKRLRKVTFINSVPKSASGKILRRELIEKVRAKL
>Maole_007931.T1
MVQNTLGVPHFLLLLSNPPPVVGPPASPPFIPPPTPGDSAFVLSPNSIRVPVLYLSLFSLGVIVSPSNPAATESEIAGQIQLCKPAIAFATSETVRKLPSLRLRTILLDSPEFDSAMMSPGEKLNPVCVAQSNTAAILYSSGTTGRVKGVELTHRNWISTVAAAHAVRPVRTRPVVSLCAVPYFHVYGFAYCVRAVALGESVVSMERFDLRLMMRAIEGLRVTHVAVAPPIVVAMLRDDHGDLMDGYDLSSLEVVACGGALLQRSVIERFKKRFPNREEFGDGVTTFSELPPNLGELVGVGRDDVGLVGANAGGNRVGAVSGAGKVANGNGDAGDGAYGLTESTAGVYRTMGPKESQVIGAVGRLMSNCQAKIVDPDTDTGLPPHKQGELWLRGPSIMKGYVDDQEATAAILDSEGWLRTGDICYIDNEGFLFFVDRMKELIKYKGYQVAPAELEHMLQTHPDIVEAAVIPYPDEEAGQVPVAFAVRQSESTTDESQIKDFIAKKVAPYKKIRRVYFIHSIPKNAPGKVLRKELIKLAISNATSSL
>Maole_022571.T1
MTLPNSQSPNFPISSNLKHGSDQSILPCKQFLASSMGTQIEIPAQDEEEHIFRSRYPPVNVPDDVTLPEFVLQHAELYAEKVAFVDAATGKECTYGEVIRDTRRFAKALRSLGLRKGKVVVVLLPNVVEYAIVALGVMAAGGVFSGANPSAHVSEIKKQVEAADAALVVTNATLFDKVRALGLPAIVLGDSGHVEGAMNWNELLEAGDRASTSTTTNEKIHQSDLCALPFSSGTTGVSKGVMLTHRNLVANLCSTLFSVGPEIVGQGKIVVMGRYELRTFLNALVTQEVTFAPIVPPIILSLVKDPIVEEFDLGKIKLRAVMTAAAPLAPELLTAFENKFPGVQVQEAYGLTEHSCITLTHGDPTKGHGIAKRNSVGFVLPNLEIKFVDPDTGRSLPKNTPGEICVRSQCVMQVFAMNLKGKNSAGYYNNKEETERTIDKNGWLHTGDIGYIDDDGDVFIVDRMKELIKYKGFQVAPAELEAILLTHPSVEDAAVVPLADEEAGEVPGACVVMNQNSKESEEDIMKYVASNVAKYKKLRVDEWRERGSEGRKNKEASKRMRKKGNRGEP
MAKSCYGEDGIYRSLRPPLNLPPNPNTSMVDFLFQNSSSFPNSTALIDHDSGEILTFCRLKSVVCNLSHALSRLGIRRNDVVLIFAPNSIYFPICFLATVALGAIASTINPSYTVREISRQVKDCNPKLVVTVPELWDKVKQFDLLYLFIKPPISVNCSIRSDCKTWHLFDLINKLDQASDLPEVSVAQGDAAALLYSSGTTGTSKGVILTHRNFIAGALMVTADQELYGERDNVFLCFLPMFHVLALSLIVYAQLQRGNAVVSMAMEKFEMEKVLGAVEKFRVTHLYVVPPVMVALAKQSAVKNYDLSSLKILGTGAAPLGKDVMEECAKVLPQADVMQGYGMTETCGVVSMEDPKTRSCLSGSTGTLLTGVESQIVSVDTLKPIPPNELGEIWFRGPNMMKGYLNNPQATKLTIDEQGWVHSGDLGYFDEKGELYVVDRIKELIKCNGFQVAPAELEGLLLAHPEILDAIVIPFPDARAGEVPIAYVVRSPNSLLTEADVQNFIADQASTRCGGNVATCHVVGEWGMHAYTKKRAAVIASDKGNADYCCNGLILGFEFVGLGVMVFGSVRLKVSGVGSLLLLEWMATAVAAGVLRWLCEAVGVTGCCGVLCSAVEEWLGLVWLEVWSGAAVGAEGWQWSVAESCEALPELQKAADWFSAATDGVWQQDGRRGRVDSPEMLVGGLARARLAGEFSHGIVMQKNGNRNGIKLVIVGEQVAGMHELVVAMHALGAPPLPSIL
>Maole_021020.T1
METETKQSEIIFRSKLPDIPIPNHLPLHAYCFENISEVASRPCLIYGPTGKTYTYEEVELTARRVASGLHRLGIRQGDVIMLLLPNSPEFIFAFLGASYRGAITTGANPFHTRSEIVKHARAAKARLIITQAANFEKVKGLGDELGVKMMCVDGAPPEGWLKFSELTESDEREMPEVEIGADDVVALPFSSGTTGLPKGVMLTHKGNVTSVAQQVDGENPNLYLRREDVILCVLPLFHIYSLNIMLCALRVGAAVAIMPKFDIVSLLELVEKYKVTVAPFVPPIVLAIAKSGEVDRYDLRSVRMVKSGAAPLGKELEDAIKAKFPNAKFGQRYLNQRNVFSLK
>Maole_010609.T1
MAVNRAKKGGSGRRLGKGFNRGCELARALTKPNMSGEKGEEGWEQRETRKEKAGSSKRLEKRIDGERESARAPMKLAFYLRGMQTAHGPYYAWPMREFKASRAAPTYSRPDLFAASSKHAWSIASFHIVSDRHFDSLHAAPSYSIFLRAELHNLNIQLPSPSPSPTESRLLHDIYGEVRLWPRWHSSYPHKLALADAHSGESLTFAQLKSMVARVSHGLTQLGIKKGDVVLILSPNSIKFALCFFGIVAIGAVATTANPSFTVSELSKQVKDSNPKLVITIPELWEKVKGFRLPVVILESQGSSNSIVSKSDRIAFFSELIGISGPAPDLPRASAKQTDTAVLLYSSGTTGNSKGVILTHRNFISASLMSASDQDFAGEMHNVFVCLVPMFHVFGLALILYSQLQRGNAVVSVPKFELEMLLRAVEKYRVTNLWVVPPIILALAKQRELLRKYDLSSLKQVGSGAAPLGKDLMEDCAKSIPQAMVLQVRLLQTGY
>Maole_010608.T1
MTETCGIIALENPMIGGRHSGSTGMLSPGIEAQIVSVEKLKPLPPNQLGEIWVRGPNMMQGYLNNPQATKQAIDKKGWVHTGDLGYFDDVGRLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEIVDAVVIPFPDAEAGEIPVAYVVRSPNSSLTEEEIQTFISNQVAPFKRLRKVTFINSVPKSASGKILRRELIEKVRAKL
>Maole_007931.T1
MVQNTLGVPHFLLLLSNPPPVVGPPASPPFIPPPTPGDSAFVLSPNSIRVPVLYLSLFSLGVIVSPSNPAATESEIAGQIQLCKPAIAFATSETVRKLPSLRLRTILLDSPEFDSAMMSPGEKLNPVCVAQSNTAAILYSSGTTGRVKGVELTHRNWISTVAAAHAVRPVRTRPVVSLCAVPYFHVYGFAYCVRAVALGESVVSMERFDLRLMMRAIEGLRVTHVAVAPPIVVAMLRDDHGDLMDGYDLSSLEVVACGGALLQRSVIERFKKRFPNREEFGDGVTTFSELPPNLGELVGVGRDDVGLVGANAGGNRVGAVSGAGKVANGNGDAGDGAYGLTESTAGVYRTMGPKESQVIGAVGRLMSNCQAKIVDPDTDTGLPPHKQGELWLRGPSIMKGYVDDQEATAAILDSEGWLRTGDICYIDNEGFLFFVDRMKELIKYKGYQVAPAELEHMLQTHPDIVEAAVIPYPDEEAGQVPVAFAVRQSESTTDESQIKDFIAKKVAPYKKIRRVYFIHSIPKNAPGKVLRKELIKLAISNATSSL
>Maole_022571.T1
MTLPNSQSPNFPISSNLKHGSDQSILPCKQFLASSMGTQIEIPAQDEEEHIFRSRYPPVNVPDDVTLPEFVLQHAELYAEKVAFVDAATGKECTYGEVIRDTRRFAKALRSLGLRKGKVVVVLLPNVVEYAIVALGVMAAGGVFSGANPSAHVSEIKKQVEAADAALVVTNATLFDKVRALGLPAIVLGDSGHVEGAMNWNELLEAGDRASTSTTTNEKIHQSDLCALPFSSGTTGVSKGVMLTHRNLVANLCSTLFSVGPEIVGQGKIVVMGRYELRTFLNALVTQEVTFAPIVPPIILSLVKDPIVEEFDLGKIKLRAVMTAAAPLAPELLTAFENKFPGVQVQEAYGLTEHSCITLTHGDPTKGHGIAKRNSVGFVLPNLEIKFVDPDTGRSLPKNTPGEICVRSQCVMQVFAMNLKGKNSAGYYNNKEETERTIDKNGWLHTGDIGYIDDDGDVFIVDRMKELIKYKGFQVAPAELEAILLTHPSVEDAAVVPLADEEAGEVPGACVVMNQNSKESEEDIMKYVASNVAKYKKLRVDEWRERGSEGRKNKEASKRMRKKGNRGEP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University