Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Magnolia biondii
Species name
Magnolia biondii is a species of flowering plant in the family Magnoliaceae (magnolia family).
Species info
Gene sequence info
Magnolia_biondii.HIDH.fa
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>MBI17344_MAGBIO
MVLFCCIVLVIRKCLYVMGKDALRNRGWLYYHTLPLRGWEGAVEMNHSRPDSVVRARVSSLKIGRIAALQRKISVSAMSSTDEIAVDFPPFLRVYKDGRVERLRGTDIVPPSINPKTGVSSKDVSILPESGVSARLFLPKLTNPTQKLPILIHYHGGGFLVETPFSPLLHNYLNSLVAEANVIVVSVHYRRAPENPLPTAYDDSWAALQWTASHANGGTESWLRNHGDFSRVFVSGESAGGNIAHHIAMRAGSHELDHGVKIHGAILVHPFFWGTEAIGNEMKYPATQAMMERLWMFVCPSTTGLDDPLINPMAVGAPSLKGVRTSMDALRDRGWLYHHTLTSSGWEGTVEMFETEGEDHVFHVLKPSSEKAVVLIKQTNIHWLPNTPILFFLSSHHLPLISHFPYISILSILAMDSTNQIALDFSPFFLVYKDGRTERFAIDIVPPSLDPKTGVSSKDVDILPELGVSARLYIPKLPNPTPKLPILVYYHGGGFILGTPSSPIYHNYLNSIVAEANVIAVSVHYRRATEHLLPTAYDDSWAALKWTASHADGGSEAWLKDHGDFTRVFVAGDSAGGNISHNIAMRAGNCELGYGVEIHGVILVHPFFWGVEGIGNEMKDLATKAKMDRLWMVVYPSTTGLDDPFINPMAVEAPSLKGLGCKRVFMCVAGKDVFRDRGWVYYHTLGSSGWEGTVEMYEEEGEDHVFHLLNPSSEKAGLMMERLAAFLKR
>MBI14947_MAGBIO
MIMDPTPPYEVEECRGVLRVYSDGSIVRSPQPSFSVPIHDDGSIIWKDVTFDPSHDLQIRLYKPSGPPGPTKLPVFYYFHGGGYCIGSRTWPNCQNYCLRLAADLRAVVVAPDYRLAPENRLPAAIEDSIAAIEWLKRQAVAEEPDTWLTDVADFGRVFISGDSAGGNIAHHLAVRFGSGSTELAPVRIRGYVYLAPFFGGTVRTRSEADCPSDAFFPLVLNDRFWRLSLPVGENTDNPIVNPFGPSSSSLETLALCPILVVVGSCDLLRDRAEEYVMKLKGWGKRVEFMEFEGKQHGFFTVDPWSEASNKLMQDIKRFMAENAESESADLPQQDEIRSLGVSKVIRADQKRFFFDLGSSSRGHFLRISEVAGADRSSIILPVSGLKQFHEMVGHFVEITKDRIEGMTGVSVWTVEPSQR
>MBI20835_MAGBIO
MDQNDQIEHDFSPFIRVYKNGRVERLLGGGSMPASVDPQTGVESKDVVISPETGLSARLYLPKLSDTLQKIPTLVYYHGGGFCIESAFSPTYHRYLNSLVAEANIVAVSVEYRLAPEHHLPIAYDDSWAALQWVASHASGGGPEAWLTDHADFDRLIVSGDSAGANIAHNLAMRAGREGVGHGVKINGAILIHPYFWGSQPVGMEVSFRKEGKPDLWTYLCPSTTGLDDPLINPVADGAPELSCLGCTRVLVCVAENDFLKERGWIYYRALESSVWKGTVEMYAVEEEGHVFHLFKPTCENAGLMLKRLAAFFNNTWRPTMKPKSRRSQNSKALHEYLGPTYFPPALSPSHLKRRVLYPFSHLYTSPLLLLLLLLSLSQSICLDSDLKINQSDQIKYDFSPFIRVYKNGRVERLLGGDRIPASVDPQTGVESKDVVISHETGLSARLYLPKLSDTLQKIPALVYYHGGGFCIESAFSPTYHRYLNSLVAKANIVAVSVEYRLAPEHHLPIAYDDSWAALQWVASHASRGGPEAWLTDHADFDRLIVSGDSAGANIAHNLAMRAGREGVGHGVKINGAILIHPYFWGSQPVGIEVSFRKKGKPDLWTYLCPSKTGLDNPLINPVADGAPDLSGLGCTRVLVCVAENDFLKERGWIYYRALESSGWKGTVEMYAVKEEGHVFHLVKPTCKKAGLMLKRVAAFINK
>MBI15088_MAGBIO
MVVEKKVVDEVSGWFHIYDNGSIDRTWTGPSEVGLLATSVPPSDTFIDGVAMRDVIIDDDLGLPARIYVPEKNPNNAMKLPMRLAPEHRLPAAIDDCYKALLWHRAVAYAEQPEPWFELGARADFNRVFLIGDSAGGDLVHEVAARAGPEEWDPLQLAGGMLLHPGFVQAVRSKSELELHTKDHPITCPMGPTAPPLGDLQLPSLLVAVAQKDLMRDTQLEYVEEMKKAGKEVELLLSPGMRHCFYLNKIAMDSDPEMAAQTDILIATISDFIRRH
>MBI20756_MAGBIO
MVAEKKVIDEVSGWFRIYDDGSIDRMWTGPPEVGFLAKSVPPSNTFVDGVATRDVFINNGLGLCSRIYIPERKPDDTAKLPVLLHFHGGGFCISRADWYMYHQIYTRLVSSAQAICISAEMRLAPEHRLPAAIDDCYEALLWLRAMARAELPEPWIELGARADFDRVFLIGDSAGGNLVHEIAARAGSEEWSPLRIAGGLLLHPGFVREERSKSEMELQSESTFLTIEMVDKFLAMALPIGSTKDHPITCPMGPDAPQLGDLRLPPLLVAVGQKDLMRDTQLEYVEEMKKAGQDVELLLSPGLGHCFYLNKIAIDSDPETAAQTDIVIATVSDFVRRH
>MBI05464_MAGBIO
MVVEKKIVDEVSGWFRIYDNGSIDRTWTGPFEVGLLATSVPPSDTFIDGVATRDVIIDDDLGLPARIYVPEKNPKKATKLPVLLHLHGGGFCIGRANWYIFQGTNPFLWKSKPCNLQNQLEFSRQQTQLPKLTTNEKLQNHRISPVPVLDANIEDPGKIASTMIDLNSRPNWIHGQPSNSQGMNALSDSNHECAIVVPVGSCNQDLEKLPAAIDDCYKALLWLRAVAYAEQPEPWLELGARADFNRVFLIGDSTDGGLIHEVAARAGPEEWDPLQLAGGMLLHPGFVQAVRSKSELELQSDSAFLTIDMVDKFLAMALPIGSTKDHPITCPMGPTAPPLGDLQLPPLLVAVAQKDLMRDTQLEYVEEMKKAGKEVELLLNPGMRHCFYLNKIAIDSDPEMAAQTDILIATISDFIRRH
>MBI15089_MAGBIO
MVAEKKVIDEVSGWFRIYDDGSIDRMWTGPPEVGFLAKNLCPHQTHSSMGSRPVMCSSTMVWASVLESIYPRGRPTIPPSCPCSYIFHGGGLHVLAELIGTCTTKSTLGLVSSAQAICISAEMRLAPEHRLPAAIDDDMKPCVWLEPWLGLNCPNHGSNLEPEQISTGLPYRRLSRRQTLFTR
>MBI16462_MAGBIO
MASEKKVVEEVPNWLRVYDDGSVDRTWTGPTQAKFLVTPVPPSETFIDGVATRDVVINPDSGLSVRIHVPEEKCNDGVRLPVLLHFHGGGFCVTQADWYIYHQFYTKLIASAPAICVSVKLRLAPEHRLPAAIDDGYAALSWLRSVARADLTEPWLGAGADFSRVFLMGDSSGGNVVHGVAARAGNEDLKPLRLAGGVPVHPGFVRAERSQSVLSGASPS
>MBI16463_MAGBIO
MFLVTPVPPSETFIDGVATRDVVINPYSDLSVRIYVPEEKCNDGVQLPVLLHFHGGGFCVTQANWYIYHQFYTKLIASAPTICVYLRLAPEHRLPAAIDDGYAALSWLRSLARADRSEPWLRARADFSRVFLMGDSSGGNVVHGVAARAGNEDLEPLRIAGGVSVHPGFVRAERSRSELEFPGSAFLTLEMIDKFLALALPVGRTKDHPITWTIASTSTRLQSTRIRIRPSKRIC
>MBI02321_MAGBIO
MGFDKKVVDEVSGWLRVYDDGSIDRSWAGPPEVEFLVTPVPPSKEFVDGVATHDVIIDPDSNLSVRIYVPEKQPLDDPKLPIILHFHGGGFCVSRADWYMYYQFYAQLVKSARAICVSVELRLAPDHRLPAAIDDCYAALLWLRSLARAELHEQCLEAADFSRVFLMGDSSGGNLVHEVAARAGSEEWEPLRLAGGVPIHPGFIRATRSKSELELPPSPLLTLEMVDKFLAMALPLGSTKDHPITCPMGPAAPPLSRLKLPPFLVAVAENDMIRDTEMEYIEAMKKAGKDVEVLLSPGVGHSFYLNKIAVDSDPNTGTQTELLIGAISNFMKRHSGGTPRAD
>MBI17774_MAGBIO
MGALSLSDQRSPFVGKDHNQNAVVVDEIQGLIKVYKDGRVDRSPVVQNVACNYGPEADVASRDVKIDGFNGVWARFYVPKHQAKLPLLIYFHGGGFCMGSAAWRCYHEFLAMLASRAGCLIMSVDYRLAPENRLPAAYDDGLTAVKWVRQQALDGSEEQSWWWSRCNFSKVYLGGDSAGACVAHHIATRLGLPGVSQGTTILKPFCLQGLILLQPFFGGEARTPSERNMVQPSNSALTLTASDVYWRLALPVGANRDHPWCNPLAKGSTKLEYLKLPSTLVYIAEMDILKDRNMEFCAAMKQAGKTVEYVVYSGVGHAFQVLYNSPMSQARTNDMISHIKSFINC
MVLFCCIVLVIRKCLYVMGKDALRNRGWLYYHTLPLRGWEGAVEMNHSRPDSVVRARVSSLKIGRIAALQRKISVSAMSSTDEIAVDFPPFLRVYKDGRVERLRGTDIVPPSINPKTGVSSKDVSILPESGVSARLFLPKLTNPTQKLPILIHYHGGGFLVETPFSPLLHNYLNSLVAEANVIVVSVHYRRAPENPLPTAYDDSWAALQWTASHANGGTESWLRNHGDFSRVFVSGESAGGNIAHHIAMRAGSHELDHGVKIHGAILVHPFFWGTEAIGNEMKYPATQAMMERLWMFVCPSTTGLDDPLINPMAVGAPSLKGVRTSMDALRDRGWLYHHTLTSSGWEGTVEMFETEGEDHVFHVLKPSSEKAVVLIKQTNIHWLPNTPILFFLSSHHLPLISHFPYISILSILAMDSTNQIALDFSPFFLVYKDGRTERFAIDIVPPSLDPKTGVSSKDVDILPELGVSARLYIPKLPNPTPKLPILVYYHGGGFILGTPSSPIYHNYLNSIVAEANVIAVSVHYRRATEHLLPTAYDDSWAALKWTASHADGGSEAWLKDHGDFTRVFVAGDSAGGNISHNIAMRAGNCELGYGVEIHGVILVHPFFWGVEGIGNEMKDLATKAKMDRLWMVVYPSTTGLDDPFINPMAVEAPSLKGLGCKRVFMCVAGKDVFRDRGWVYYHTLGSSGWEGTVEMYEEEGEDHVFHLLNPSSEKAGLMMERLAAFLKR
>MBI14947_MAGBIO
MIMDPTPPYEVEECRGVLRVYSDGSIVRSPQPSFSVPIHDDGSIIWKDVTFDPSHDLQIRLYKPSGPPGPTKLPVFYYFHGGGYCIGSRTWPNCQNYCLRLAADLRAVVVAPDYRLAPENRLPAAIEDSIAAIEWLKRQAVAEEPDTWLTDVADFGRVFISGDSAGGNIAHHLAVRFGSGSTELAPVRIRGYVYLAPFFGGTVRTRSEADCPSDAFFPLVLNDRFWRLSLPVGENTDNPIVNPFGPSSSSLETLALCPILVVVGSCDLLRDRAEEYVMKLKGWGKRVEFMEFEGKQHGFFTVDPWSEASNKLMQDIKRFMAENAESESADLPQQDEIRSLGVSKVIRADQKRFFFDLGSSSRGHFLRISEVAGADRSSIILPVSGLKQFHEMVGHFVEITKDRIEGMTGVSVWTVEPSQR
>MBI20835_MAGBIO
MDQNDQIEHDFSPFIRVYKNGRVERLLGGGSMPASVDPQTGVESKDVVISPETGLSARLYLPKLSDTLQKIPTLVYYHGGGFCIESAFSPTYHRYLNSLVAEANIVAVSVEYRLAPEHHLPIAYDDSWAALQWVASHASGGGPEAWLTDHADFDRLIVSGDSAGANIAHNLAMRAGREGVGHGVKINGAILIHPYFWGSQPVGMEVSFRKEGKPDLWTYLCPSTTGLDDPLINPVADGAPELSCLGCTRVLVCVAENDFLKERGWIYYRALESSVWKGTVEMYAVEEEGHVFHLFKPTCENAGLMLKRLAAFFNNTWRPTMKPKSRRSQNSKALHEYLGPTYFPPALSPSHLKRRVLYPFSHLYTSPLLLLLLLLSLSQSICLDSDLKINQSDQIKYDFSPFIRVYKNGRVERLLGGDRIPASVDPQTGVESKDVVISHETGLSARLYLPKLSDTLQKIPALVYYHGGGFCIESAFSPTYHRYLNSLVAKANIVAVSVEYRLAPEHHLPIAYDDSWAALQWVASHASRGGPEAWLTDHADFDRLIVSGDSAGANIAHNLAMRAGREGVGHGVKINGAILIHPYFWGSQPVGIEVSFRKKGKPDLWTYLCPSKTGLDNPLINPVADGAPDLSGLGCTRVLVCVAENDFLKERGWIYYRALESSGWKGTVEMYAVKEEGHVFHLVKPTCKKAGLMLKRVAAFINK
>MBI15088_MAGBIO
MVVEKKVVDEVSGWFHIYDNGSIDRTWTGPSEVGLLATSVPPSDTFIDGVAMRDVIIDDDLGLPARIYVPEKNPNNAMKLPMRLAPEHRLPAAIDDCYKALLWHRAVAYAEQPEPWFELGARADFNRVFLIGDSAGGDLVHEVAARAGPEEWDPLQLAGGMLLHPGFVQAVRSKSELELHTKDHPITCPMGPTAPPLGDLQLPSLLVAVAQKDLMRDTQLEYVEEMKKAGKEVELLLSPGMRHCFYLNKIAMDSDPEMAAQTDILIATISDFIRRH
>MBI20756_MAGBIO
MVAEKKVIDEVSGWFRIYDDGSIDRMWTGPPEVGFLAKSVPPSNTFVDGVATRDVFINNGLGLCSRIYIPERKPDDTAKLPVLLHFHGGGFCISRADWYMYHQIYTRLVSSAQAICISAEMRLAPEHRLPAAIDDCYEALLWLRAMARAELPEPWIELGARADFDRVFLIGDSAGGNLVHEIAARAGSEEWSPLRIAGGLLLHPGFVREERSKSEMELQSESTFLTIEMVDKFLAMALPIGSTKDHPITCPMGPDAPQLGDLRLPPLLVAVGQKDLMRDTQLEYVEEMKKAGQDVELLLSPGLGHCFYLNKIAIDSDPETAAQTDIVIATVSDFVRRH
>MBI05464_MAGBIO
MVVEKKIVDEVSGWFRIYDNGSIDRTWTGPFEVGLLATSVPPSDTFIDGVATRDVIIDDDLGLPARIYVPEKNPKKATKLPVLLHLHGGGFCIGRANWYIFQGTNPFLWKSKPCNLQNQLEFSRQQTQLPKLTTNEKLQNHRISPVPVLDANIEDPGKIASTMIDLNSRPNWIHGQPSNSQGMNALSDSNHECAIVVPVGSCNQDLEKLPAAIDDCYKALLWLRAVAYAEQPEPWLELGARADFNRVFLIGDSTDGGLIHEVAARAGPEEWDPLQLAGGMLLHPGFVQAVRSKSELELQSDSAFLTIDMVDKFLAMALPIGSTKDHPITCPMGPTAPPLGDLQLPPLLVAVAQKDLMRDTQLEYVEEMKKAGKEVELLLNPGMRHCFYLNKIAIDSDPEMAAQTDILIATISDFIRRH
>MBI15089_MAGBIO
MVAEKKVIDEVSGWFRIYDDGSIDRMWTGPPEVGFLAKNLCPHQTHSSMGSRPVMCSSTMVWASVLESIYPRGRPTIPPSCPCSYIFHGGGLHVLAELIGTCTTKSTLGLVSSAQAICISAEMRLAPEHRLPAAIDDDMKPCVWLEPWLGLNCPNHGSNLEPEQISTGLPYRRLSRRQTLFTR
>MBI16462_MAGBIO
MASEKKVVEEVPNWLRVYDDGSVDRTWTGPTQAKFLVTPVPPSETFIDGVATRDVVINPDSGLSVRIHVPEEKCNDGVRLPVLLHFHGGGFCVTQADWYIYHQFYTKLIASAPAICVSVKLRLAPEHRLPAAIDDGYAALSWLRSVARADLTEPWLGAGADFSRVFLMGDSSGGNVVHGVAARAGNEDLKPLRLAGGVPVHPGFVRAERSQSVLSGASPS
>MBI16463_MAGBIO
MFLVTPVPPSETFIDGVATRDVVINPYSDLSVRIYVPEEKCNDGVQLPVLLHFHGGGFCVTQANWYIYHQFYTKLIASAPTICVYLRLAPEHRLPAAIDDGYAALSWLRSLARADRSEPWLRARADFSRVFLMGDSSGGNVVHGVAARAGNEDLEPLRIAGGVSVHPGFVRAERSRSELEFPGSAFLTLEMIDKFLALALPVGRTKDHPITWTIASTSTRLQSTRIRIRPSKRIC
>MBI02321_MAGBIO
MGFDKKVVDEVSGWLRVYDDGSIDRSWAGPPEVEFLVTPVPPSKEFVDGVATHDVIIDPDSNLSVRIYVPEKQPLDDPKLPIILHFHGGGFCVSRADWYMYYQFYAQLVKSARAICVSVELRLAPDHRLPAAIDDCYAALLWLRSLARAELHEQCLEAADFSRVFLMGDSSGGNLVHEVAARAGSEEWEPLRLAGGVPIHPGFIRATRSKSELELPPSPLLTLEMVDKFLAMALPLGSTKDHPITCPMGPAAPPLSRLKLPPFLVAVAENDMIRDTEMEYIEAMKKAGKDVEVLLSPGVGHSFYLNKIAVDSDPNTGTQTELLIGAISNFMKRHSGGTPRAD
>MBI17774_MAGBIO
MGALSLSDQRSPFVGKDHNQNAVVVDEIQGLIKVYKDGRVDRSPVVQNVACNYGPEADVASRDVKIDGFNGVWARFYVPKHQAKLPLLIYFHGGGFCMGSAAWRCYHEFLAMLASRAGCLIMSVDYRLAPENRLPAAYDDGLTAVKWVRQQALDGSEEQSWWWSRCNFSKVYLGGDSAGACVAHHIATRLGLPGVSQGTTILKPFCLQGLILLQPFFGGEARTPSERNMVQPSNSALTLTASDVYWRLALPVGANRDHPWCNPLAKGSTKLEYLKLPSTLVYIAEMDILKDRNMEFCAAMKQAGKTVEYVVYSGVGHAFQVLYNSPMSQARTNDMISHIKSFINC
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University