Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Magnolia biondii
Species name
Magnolia biondii is a species of flowering plant in the family Magnoliaceae (magnolia family).
Species info
Gene sequence info
Magnolia_biondii.CHS.fa
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>MBI09529_MAGBIO
MSRADVNDNASHCLATNKRPHTPGKAVILALGKAFPKQLVPQEFLVEAYFRNTKCEDGAMKEKLERLCKTTTVKTRYTVMSKEILDKYPELATEGSPTIKQRLDIANTAVLEMAVEASLACIKEWGRPATDITHVVYVSSSEIRLPGGDLYLASQLGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGYRPPNMSRPYDLVGAALFGDGAAAVVVGTDPLTATEMPFMELNYAVQQFLPGTQNIINGHLSEEGINFKLGRDLPQKIEDHIQEFCKKLMKKAGLKEFNDLFWAVHPGGPAILNRVESKLKLREEKLKCSRRALMDYGNVSSNTIFYVMDYMREELKREGGEEWGLVLAFGPGITFEGILVRSL
>MBI21059_MAGBIO
MVSLDVIRKAQRAEGPATVMAIGTATPPNAVDQNTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEEILTENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAARAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPIPGVESPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFDPLGISDWNSLFWIAHPGGPAILDQVELKLGLKAEKLRATRHVLSEFGNMSSACVLFILDEMRRKSAEDGLVTTGEGLEWGVLFGFGPGLTVETVVLHSVAAK
>MBI38974_MAGBIO
MGSLDGLDCVPKRATPGKTTIMAIGKAFPPQLVMQEFLVDGYFKNTKCNDPDLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVTQRLDISNKAVTQMAVEASQACIKSWGRPVSDITHLVYISSSEARLPGGDLYLARGLGLSPEVSRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIVGFKPPSASRPYDLVGAALFGDGAGAMILGTDAILGIETPFFELHSAIQQFLPDTEKTIDGRLTEEGINFKLGRDLPQIIEDNIEGFCNKLMKEIGYGGADYNKLFWAVHPGGPAILNRLEKRLDLLPEKLSGSRRALMDYGNASSNTIVYVMEYMMEESFKMKERGEKDSDWGLILAFGPGITFEGILARNLL
>MBI16823_MAGBIO
MEKNSRRREYQTAALCGAGREREREREREGGRAGHLQQSPYKKRRHNQPLVPSIHPSLIHTPTYQLPWSAEMVTVDAIRKSQRAEGTATVMAIGTANPPNVVDQSTYPDYYFRVTNSEHKVEIKQKFKRMCEKSTIKKRYMYLTEEILKENPNVCAYMAPSFDTRQDMVVVEVPKLGKEAASKAIMEWGQPKSNITHLIFCTTSGVDMPGADYQLTKLLHLRPSVKRFVLYQQGCFAGGTVLRLAKDLAENNKGARVLAICSEITAITFRGPSDTHHDSLVGQALFGDGAAAVIVGADPIPGIEKPLFELISAGQTILPDSDGAIDGHLREVGLTFHLMKDVPGLISNNIEKSLIEALEPLGISDWNSLFWIMHPGGPAILDHVEMKLGLKAEKLRATRHVLSEYGNMSSACVLFILDEMRKKSVEEGCKTTGEGLEWGVLFGFGPGLTVETVVLHSVAG
>MBI02487_MAGBIO
MSTVSIVQIRKAQRAEGPATVLAIGTATPSNEVIQAEYPDYYFRITKSEHMTELKEKFKRIYY
>MBI02494_MAGBIO
MSAQQGVQSRAMSMVSINDIRRAQRAEGPATVLAIGTATPPNEVMQADYPDYYFRITNSDKSMIRKRHLYLTEDMLKENPDMCASMAPTLNARQDIVTIEVPKLGKEAAAKAIKEWGQPKSKITHVVFCATGGVDMPGADYQLTKLLGLRPSVKRYMMYQIGCFAGGTVLRLAKDLAENNAGARVLVVCSEITFATFRGPSDTYLDGLVGQALFGDGAAAVIIGADPNSAERPLFQFVSAAQTILPDSDGAINGHLREAGLTFHLLKDVPGIISKNIEKSLVDAFEPLGINDWNSIFWIAHPGGPAILDQVEMKLNLKTEKLRATRHVLSEYGNMASACVLFILDEMRRKSVEEGKATTGEGLDWGVLFGFGPGLTVETVVLHSLPITVDH
>MBI02490_MAGBIO
MAPSLDARQDMVVVEVPKLGKEAATKAIKEWGHPKSKITHLIFCTTSGVDMPGADYQLTKLLGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPNPSEKPLFQLVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGINDWNSIFWIAHPGGPAILDQVETKLNLKAEKMRATRHVLSEYGNMSSACSVYFG
>MBI02491_MAGBIO
MSTVSIDAIRKAQRAEGPATVLAIGTATPSNEVIQADYPDYYFRVTKSEHMTELKEKFKRIIIITITIILGKVYGRLFIEHQPSFTCAWTSWEVVITIVLL
>MBI02496_MAGBIO
TIPSVSKRLGTPIKRFFYILVQTSAQQGVQSKAMSTVSIDAIRKAQRADGPATVLAIGTATPSNEVIQADYPDYYFKITKSEHMTELKEKFKRMCDKSMIRKRYMHLTEDILKENPDMCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGHPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPNSSERPLFQLVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGINDWNSIFWIAHPGGPAILDQVEAKLNLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAEEGKGTTGEGLDWGVLFGFGPGLTVETVVLHSLPITGAH
>MBI02486_MAGBIO
MIRKRYMHLTEELLNENPNMCEYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGHPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPNSSERPLFQLVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGINDWNSIFWIAHPGGPAILDQVETKLNLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSVEEGKTTTGEGLDWGVLFGFGPGLTVETVVLHSLPLTT
MSRADVNDNASHCLATNKRPHTPGKAVILALGKAFPKQLVPQEFLVEAYFRNTKCEDGAMKEKLERLCKTTTVKTRYTVMSKEILDKYPELATEGSPTIKQRLDIANTAVLEMAVEASLACIKEWGRPATDITHVVYVSSSEIRLPGGDLYLASQLGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGYRPPNMSRPYDLVGAALFGDGAAAVVVGTDPLTATEMPFMELNYAVQQFLPGTQNIINGHLSEEGINFKLGRDLPQKIEDHIQEFCKKLMKKAGLKEFNDLFWAVHPGGPAILNRVESKLKLREEKLKCSRRALMDYGNVSSNTIFYVMDYMREELKREGGEEWGLVLAFGPGITFEGILVRSL
>MBI21059_MAGBIO
MVSLDVIRKAQRAEGPATVMAIGTATPPNAVDQNTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEEILTENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAARAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPIPGVESPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFDPLGISDWNSLFWIAHPGGPAILDQVELKLGLKAEKLRATRHVLSEFGNMSSACVLFILDEMRRKSAEDGLVTTGEGLEWGVLFGFGPGLTVETVVLHSVAAK
>MBI38974_MAGBIO
MGSLDGLDCVPKRATPGKTTIMAIGKAFPPQLVMQEFLVDGYFKNTKCNDPDLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVTQRLDISNKAVTQMAVEASQACIKSWGRPVSDITHLVYISSSEARLPGGDLYLARGLGLSPEVSRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIVGFKPPSASRPYDLVGAALFGDGAGAMILGTDAILGIETPFFELHSAIQQFLPDTEKTIDGRLTEEGINFKLGRDLPQIIEDNIEGFCNKLMKEIGYGGADYNKLFWAVHPGGPAILNRLEKRLDLLPEKLSGSRRALMDYGNASSNTIVYVMEYMMEESFKMKERGEKDSDWGLILAFGPGITFEGILARNLL
>MBI16823_MAGBIO
MEKNSRRREYQTAALCGAGREREREREREGGRAGHLQQSPYKKRRHNQPLVPSIHPSLIHTPTYQLPWSAEMVTVDAIRKSQRAEGTATVMAIGTANPPNVVDQSTYPDYYFRVTNSEHKVEIKQKFKRMCEKSTIKKRYMYLTEEILKENPNVCAYMAPSFDTRQDMVVVEVPKLGKEAASKAIMEWGQPKSNITHLIFCTTSGVDMPGADYQLTKLLHLRPSVKRFVLYQQGCFAGGTVLRLAKDLAENNKGARVLAICSEITAITFRGPSDTHHDSLVGQALFGDGAAAVIVGADPIPGIEKPLFELISAGQTILPDSDGAIDGHLREVGLTFHLMKDVPGLISNNIEKSLIEALEPLGISDWNSLFWIMHPGGPAILDHVEMKLGLKAEKLRATRHVLSEYGNMSSACVLFILDEMRKKSVEEGCKTTGEGLEWGVLFGFGPGLTVETVVLHSVAG
>MBI02487_MAGBIO
MSTVSIVQIRKAQRAEGPATVLAIGTATPSNEVIQAEYPDYYFRITKSEHMTELKEKFKRIYY
>MBI02494_MAGBIO
MSAQQGVQSRAMSMVSINDIRRAQRAEGPATVLAIGTATPPNEVMQADYPDYYFRITNSDKSMIRKRHLYLTEDMLKENPDMCASMAPTLNARQDIVTIEVPKLGKEAAAKAIKEWGQPKSKITHVVFCATGGVDMPGADYQLTKLLGLRPSVKRYMMYQIGCFAGGTVLRLAKDLAENNAGARVLVVCSEITFATFRGPSDTYLDGLVGQALFGDGAAAVIIGADPNSAERPLFQFVSAAQTILPDSDGAINGHLREAGLTFHLLKDVPGIISKNIEKSLVDAFEPLGINDWNSIFWIAHPGGPAILDQVEMKLNLKTEKLRATRHVLSEYGNMASACVLFILDEMRRKSVEEGKATTGEGLDWGVLFGFGPGLTVETVVLHSLPITVDH
>MBI02490_MAGBIO
MAPSLDARQDMVVVEVPKLGKEAATKAIKEWGHPKSKITHLIFCTTSGVDMPGADYQLTKLLGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPNPSEKPLFQLVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGINDWNSIFWIAHPGGPAILDQVETKLNLKAEKMRATRHVLSEYGNMSSACSVYFG
>MBI02491_MAGBIO
MSTVSIDAIRKAQRAEGPATVLAIGTATPSNEVIQADYPDYYFRVTKSEHMTELKEKFKRIIIITITIILGKVYGRLFIEHQPSFTCAWTSWEVVITIVLL
>MBI02496_MAGBIO
TIPSVSKRLGTPIKRFFYILVQTSAQQGVQSKAMSTVSIDAIRKAQRADGPATVLAIGTATPSNEVIQADYPDYYFKITKSEHMTELKEKFKRMCDKSMIRKRYMHLTEDILKENPDMCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGHPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPNSSERPLFQLVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGINDWNSIFWIAHPGGPAILDQVEAKLNLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAEEGKGTTGEGLDWGVLFGFGPGLTVETVVLHSLPITGAH
>MBI02486_MAGBIO
MIRKRYMHLTEELLNENPNMCEYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGHPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGADPNSSERPLFQLVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGINDWNSIFWIAHPGGPAILDQVETKLNLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSVEEGKTTTGEGLDWGVLFGFGPGLTVETVVLHSLPLTT
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University