Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Macleaya cordata
Species name
Macleaya cordata is a species of flowering plant in the family Papaveraceae (poppy family).
Species info
Gene sequence info
Macleaya_cordata.OMT.fa
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>rna-gnl|WGS:MVGT|mrna.BVC80_1227g17
MDSSTDNDQQLAKDNELIQAQTHVYNHIFTFISSMSLKCAVQLGIPDIIHNNHGQPITLSGLVNALSLPPTKTAFVYRLMRILVHSGYFATQKIDENQEEEGFLLTSSSRLLLKDSKNTFSSIVLTVVDPVLVTPFFSLSDWFQGINGSTTSFEAAHGMGFWSFLEQHPEYSKTFNDAMANDSRLMIMSSVIVKEGKEVFENLKTLVDVGGGDGTSAKAIAEAFPHLKCLVLDLPHVVADHLSKSATETSFTGGATLRPERVVAPPASSDDDCVKILKRCREAIPLREGGGKVILIEIVMEDKDYNMKLQKQEADDDERTELQLYFDMMMMTTFDGKERNEKEWEKLFIESGFSDYKITPVSGFRSLIEVYP
>rna-gnl|WGS:MVGT|mrna.BVC80_1807g3
MDSTAQEMKKNELVQAQAHVFNNICGFFSSMSLKCAVELGIPDIIHNHGKPMPLSDLVEALSLPPSKTENVYRLMRLLVHSGLFAKQKIDENQDEEGYLLTTSSNFLLHNTEFSLADFVINLVNPALVKPGHILSDWFRTGESTAFEAVHGVPFWRHLMQNPEYEKGFSNIMAANSKLVMSDIVNSCKSVFENLRSVVDVGGGTGTSARVIVEAFPHLKCLVLDLPNLVANLPGNSNLEFIGGDMFESIPRADAIILKHVLHNWGDDESLKILKSCREAIPSKKEGGKVIVIEIVVEEDSKLENDQLTKTQLYFDMLMMTTFNGKERSEKQWEKLFLEAGFSDYKITTLSGFSSLIEVFP
>rna-gnl|WGS:MVGT|mrna.BVC80_605g10
MEVKKSDQANQAKTWKLIYGFAESQVLKCAVELDIAGTIHNHGQPMTLSELASQLPAQPVNSDRLYRVMRYLVHMKLFTKENVQGEEMRYGLAPSAKYLIKGWEKSIVPSILSLQDKVLMRPWNHLKDAVIGDCTAFEKVFGKNLWVYLADHPDKNKIFNESMACNSRLLTSALVHDCKSVFEGLTSLVDCGGGTGTAAKAIFKAFPHIKCSVYDLPHVIADSPSDPDIVRIAGDMFKFIPSADAILLKWILHDWDDNECIQILKLCKEVVPREGGKVIIVDIVLNVNSKHPFSKMRLRFDLGMMLRTGGKERTEEEWKKLIHAAGFTSYKITHISAIQSCILHDWNDDECIQILKKCKEALPREGGKVIIVDVVLDMDMSHPYSKIRFTLDLDMMLNTGGKERTVEEWKKLIDAAGFASYKITQISAVQSVIEAYPY
>rna-gnl|WGS:MVGT|mrna.BVC80_645g9
MGLIDKPESQEVDIKAQAHLWNIIYGFADSLVLRCAVEIGIADIIKNNNGSISVTELSSKLPISNVNCDNLYRVLRYLVHMGILKEDSDINGVKLYSLQPVATLLLRDAERSMVPIILGMTQKDFMIPWHFMKEGLGNGSTAFEKGMGMTIWQYLEGHPEQSQLFNEGMAGETRLLTKSLIDGCRDTFEGLTSLVDVGGGNGTTIKGIYDAFPHIKCSLYDLPHVIANSHDHPNIERIPGDMFKSVPSAQAILLKLILHDWTDEECVSILEKCREAVPKETGKVIIVDVALEEESQHELTKTRLILDIDMLVNTGGRERTEDDWEKLLKRAGFRGHKIRHIAAIQSVIEAFP
>rna-gnl|WGS:MVGT|mrna.BVC80_8595g12
MESTTQEVKDNELIQAQTHVFNHIFSFVSSMSLKCAVQLGIPEIIHNHGQPITLSSLVEALSLPPTKSYSIYRLMRLLVHSGFFACQKIDENQQEEGFLLTPSSRLLLKDNTKNLSSFLLNMLDPVLITPWHFLSAWFQGNGSTAFEAAHDMTLWNFLEQYPEFNKNFNDAMASDSGFVMSVIVNDCKAVFENLRSLVDVGGGTGSVAQALAKAFPHLNCLVFDLPNVVANLPGSKNLNYIGGDMFESIPCADAVFMKFVLHAWSDSDCIKILKRCREAIPSREEGGKVIIIEIVMEENRKQEDKSTETQLFFDMLMMTVVTGKERTEKEWKKLFLESGFSDYKMTPVLGFRSLIEYVLHDWSDKDCVKILKRCREAIPCREEGGKVIIIEIVLEDRKQEHETTETQFFFDIQMMVFNGGKERSEREWKELFLESGFTEYKITPLPGFRSLIEVYP
>rna-gnl|WGS:MVGT|mrna.BVC80_8595g19
MDSTAQGVKDTELMQAQVHVFNHVFGFVSSMSLKCTVQLGIPDIIHNHGRPMTLSSLVDALSLPPTKTDSVYRLMRLLVHSGFFARQKIDENQEEEGFVLTPSSKLLLKDDNTNKYTSLSSFVINLQDPVFVTPWLSLLSAWFQGSGSTVFEDSHGMAFWNFMEQHPEPKNNFNDAMASDSSLVMMSTLMVNESKAVFENLRSLVDVGGGNGASAQAIAEVFPHLKCLVLDLPHVVADHLQKCTKNLDFIGGNMFESIPCANAVLMKSILYNWSDNDCVKILKRCREAIPGREEGGKVIIIDVVMEDRKQEHDSTEIQLLFDMIMMTIGGKEKL
>rna-gnl|WGS:MVGT|mrna.BVC80_8595g16
MDSSASTEVKGNELLQVHAHVWKYAFSYISSMCLKCAVQLSIPEIIHNHGKPMTLSSLVDALSLPPSKTEAVNRLMRFLIHAGFFATQKLDENQEDLEEVAEEGFLLTPSSRYLIKDDTNTLSSIVLAIVDPVLVTPFYSLSDWFRGNGSTTFEAGQGMGIWNFLEHHPEYSKNFNYAMANDSRPIMSVVVNEGKAVFENLKSLVDVGGGNGTSAKAIAEAFPHLKCLVLDLPHVVADHIPKINTKNLDFIGGNMFDSIPRADAVLMKNILHDWSDKDCVKILKRCREAIPGREEGGKMIILDVVMEDRKQEHDSTEIQLLFDMIMMTIGGKERTEKEWKKLFLESGFTDYKITPLLGFRSIIEVYP
>rna-gnl|WGS:MVGT|mrna.BVC80_8595g14
MDSTTQEMKKSEMVQAQAHVFNNICGFFSSMSLKCAVELGIPDIIHKHGKPMPLSDLVEALSLPPSKTEAMYRLMRLLVHSGFFAKQKIDENQEEEGYLLTISSSFLLQNTEFSLAPFVISILTPALVKPGHILCDWFRTGESTAFETDHGIPFWRHLMQNPEYEKGFSNTMATNSKLVMSDIVSNCKSVLENLRSVVDVGGGTGTSARVIAEAFPHLKCMVLDLPNLVANLPGKNNLEFIGGDMFESIPRADAIILKNVLHNWGDDESVKILKRCREAIPPKKEGGKVMVIEIVVEEDSKLENDQLTKTQLYFDMLMMTTFNGKERSEKQWEKLFLEAGFTDYKITPLMGFSSLIEAFP
>rna-gnl|WGS:MVGT|mrna.BVC80_9005g36
MEIQLGDQEQEMKWQGQVWNHICGSVDTAVLKCSIELGIFDIIHNSGKPMITLSELSTSPSLVSVKTENLYRLLRYLAHMNLITINSVEGNETFSLTNIAKLLLRNQEKSLVDWALGIGDEILMAVWHELSSSCSTPADGPTACQKVHSMGCYDLTEKNPKLNQVINNAMASDTRLVMPAFVQGCHEVLNGISSLVDIGGGIGTAMSYVVKAFPHIKCTAFDLPHVVATAPQYPGVDLVGGNMFEFIPPADAVLLKFMLHNWEDEECVKLLKRCKEAIPGDRGKVIIIEIVLDQDEDENDDDDDNYELIRARLSLDLDMMLSSGGRERTKDEWRVLLIEMAGFSRHEIIPICAIQSVIVAYP
>rna-gnl|WGS:MVGT|mrna.BVC80_9005g35
MEIQLGDQEQEMKWQGQVWNHICGSVDSAVLKCTIELGLLDIIHSSPKPITLSELSSSPSLSSLKAQNLYRLLRYLSHMNLITSNIVEGNETFSLTDLSKLLLKNQERSLKDWVLGIDDEHSINSWHELSSYCCSPDDAPTPFVKLHGKTLWELAEEVPEVNELINNGMACDTRMVMPAFIKGCEKILNGITKLVDIGGGTGAAISYVVKAFPQIKGTVFDLPHVVATAPEIPGVEMVGGDMFECIPSADALLLKFMLHNWKDDECIKLLKRCKETIPTDQGKVIIIEMVLDQDEDDDDLTQARLSLDLDMMLSSGGKERTKDEWRVLLETAGFSRIEFIPIFAIQSVIVAYP
>rna-gnl|WGS:MVGT|mrna.BVC80_9087g12
MEKVDGKRREEQEERLQGQADIWSHMFAFADSMALKCAVELGIPDIINSHGRPITISEITDAIITVSPVPSSSPDTNCLSRVMRLLVRKRIFSVQIHPESGQTLYGLTPSSKWLLKDSEFSLAPMVLAELHPWLISPWNYLSKCVQEGGIAFEKAHGSEIWDFALANQDFNKLFNGGMACTAKIVVNAILVNYKEGFDGVGSIVDVGGGTGMMIGEIVKAHPRIQGINFDLPHVVATAPECEGVAHVGGDMFVDIPHADAVIMKWIMHDWSDKDCVRILKNCRKAIPKETGKVIIFDCVLPPDGPDDKGGLFDNTRLVFDLLMIAHSSGGKERTEVEWKRLLKDGGFPSYKIIQIPALLSIIEAYPE
MDSSTDNDQQLAKDNELIQAQTHVYNHIFTFISSMSLKCAVQLGIPDIIHNNHGQPITLSGLVNALSLPPTKTAFVYRLMRILVHSGYFATQKIDENQEEEGFLLTSSSRLLLKDSKNTFSSIVLTVVDPVLVTPFFSLSDWFQGINGSTTSFEAAHGMGFWSFLEQHPEYSKTFNDAMANDSRLMIMSSVIVKEGKEVFENLKTLVDVGGGDGTSAKAIAEAFPHLKCLVLDLPHVVADHLSKSATETSFTGGATLRPERVVAPPASSDDDCVKILKRCREAIPLREGGGKVILIEIVMEDKDYNMKLQKQEADDDERTELQLYFDMMMMTTFDGKERNEKEWEKLFIESGFSDYKITPVSGFRSLIEVYP
>rna-gnl|WGS:MVGT|mrna.BVC80_1807g3
MDSTAQEMKKNELVQAQAHVFNNICGFFSSMSLKCAVELGIPDIIHNHGKPMPLSDLVEALSLPPSKTENVYRLMRLLVHSGLFAKQKIDENQDEEGYLLTTSSNFLLHNTEFSLADFVINLVNPALVKPGHILSDWFRTGESTAFEAVHGVPFWRHLMQNPEYEKGFSNIMAANSKLVMSDIVNSCKSVFENLRSVVDVGGGTGTSARVIVEAFPHLKCLVLDLPNLVANLPGNSNLEFIGGDMFESIPRADAIILKHVLHNWGDDESLKILKSCREAIPSKKEGGKVIVIEIVVEEDSKLENDQLTKTQLYFDMLMMTTFNGKERSEKQWEKLFLEAGFSDYKITTLSGFSSLIEVFP
>rna-gnl|WGS:MVGT|mrna.BVC80_605g10
MEVKKSDQANQAKTWKLIYGFAESQVLKCAVELDIAGTIHNHGQPMTLSELASQLPAQPVNSDRLYRVMRYLVHMKLFTKENVQGEEMRYGLAPSAKYLIKGWEKSIVPSILSLQDKVLMRPWNHLKDAVIGDCTAFEKVFGKNLWVYLADHPDKNKIFNESMACNSRLLTSALVHDCKSVFEGLTSLVDCGGGTGTAAKAIFKAFPHIKCSVYDLPHVIADSPSDPDIVRIAGDMFKFIPSADAILLKWILHDWDDNECIQILKLCKEVVPREGGKVIIVDIVLNVNSKHPFSKMRLRFDLGMMLRTGGKERTEEEWKKLIHAAGFTSYKITHISAIQSCILHDWNDDECIQILKKCKEALPREGGKVIIVDVVLDMDMSHPYSKIRFTLDLDMMLNTGGKERTVEEWKKLIDAAGFASYKITQISAVQSVIEAYPY
>rna-gnl|WGS:MVGT|mrna.BVC80_645g9
MGLIDKPESQEVDIKAQAHLWNIIYGFADSLVLRCAVEIGIADIIKNNNGSISVTELSSKLPISNVNCDNLYRVLRYLVHMGILKEDSDINGVKLYSLQPVATLLLRDAERSMVPIILGMTQKDFMIPWHFMKEGLGNGSTAFEKGMGMTIWQYLEGHPEQSQLFNEGMAGETRLLTKSLIDGCRDTFEGLTSLVDVGGGNGTTIKGIYDAFPHIKCSLYDLPHVIANSHDHPNIERIPGDMFKSVPSAQAILLKLILHDWTDEECVSILEKCREAVPKETGKVIIVDVALEEESQHELTKTRLILDIDMLVNTGGRERTEDDWEKLLKRAGFRGHKIRHIAAIQSVIEAFP
>rna-gnl|WGS:MVGT|mrna.BVC80_8595g12
MESTTQEVKDNELIQAQTHVFNHIFSFVSSMSLKCAVQLGIPEIIHNHGQPITLSSLVEALSLPPTKSYSIYRLMRLLVHSGFFACQKIDENQQEEGFLLTPSSRLLLKDNTKNLSSFLLNMLDPVLITPWHFLSAWFQGNGSTAFEAAHDMTLWNFLEQYPEFNKNFNDAMASDSGFVMSVIVNDCKAVFENLRSLVDVGGGTGSVAQALAKAFPHLNCLVFDLPNVVANLPGSKNLNYIGGDMFESIPCADAVFMKFVLHAWSDSDCIKILKRCREAIPSREEGGKVIIIEIVMEENRKQEDKSTETQLFFDMLMMTVVTGKERTEKEWKKLFLESGFSDYKMTPVLGFRSLIEYVLHDWSDKDCVKILKRCREAIPCREEGGKVIIIEIVLEDRKQEHETTETQFFFDIQMMVFNGGKERSEREWKELFLESGFTEYKITPLPGFRSLIEVYP
>rna-gnl|WGS:MVGT|mrna.BVC80_8595g19
MDSTAQGVKDTELMQAQVHVFNHVFGFVSSMSLKCTVQLGIPDIIHNHGRPMTLSSLVDALSLPPTKTDSVYRLMRLLVHSGFFARQKIDENQEEEGFVLTPSSKLLLKDDNTNKYTSLSSFVINLQDPVFVTPWLSLLSAWFQGSGSTVFEDSHGMAFWNFMEQHPEPKNNFNDAMASDSSLVMMSTLMVNESKAVFENLRSLVDVGGGNGASAQAIAEVFPHLKCLVLDLPHVVADHLQKCTKNLDFIGGNMFESIPCANAVLMKSILYNWSDNDCVKILKRCREAIPGREEGGKVIIIDVVMEDRKQEHDSTEIQLLFDMIMMTIGGKEKL
>rna-gnl|WGS:MVGT|mrna.BVC80_8595g16
MDSSASTEVKGNELLQVHAHVWKYAFSYISSMCLKCAVQLSIPEIIHNHGKPMTLSSLVDALSLPPSKTEAVNRLMRFLIHAGFFATQKLDENQEDLEEVAEEGFLLTPSSRYLIKDDTNTLSSIVLAIVDPVLVTPFYSLSDWFRGNGSTTFEAGQGMGIWNFLEHHPEYSKNFNYAMANDSRPIMSVVVNEGKAVFENLKSLVDVGGGNGTSAKAIAEAFPHLKCLVLDLPHVVADHIPKINTKNLDFIGGNMFDSIPRADAVLMKNILHDWSDKDCVKILKRCREAIPGREEGGKMIILDVVMEDRKQEHDSTEIQLLFDMIMMTIGGKERTEKEWKKLFLESGFTDYKITPLLGFRSIIEVYP
>rna-gnl|WGS:MVGT|mrna.BVC80_8595g14
MDSTTQEMKKSEMVQAQAHVFNNICGFFSSMSLKCAVELGIPDIIHKHGKPMPLSDLVEALSLPPSKTEAMYRLMRLLVHSGFFAKQKIDENQEEEGYLLTISSSFLLQNTEFSLAPFVISILTPALVKPGHILCDWFRTGESTAFETDHGIPFWRHLMQNPEYEKGFSNTMATNSKLVMSDIVSNCKSVLENLRSVVDVGGGTGTSARVIAEAFPHLKCMVLDLPNLVANLPGKNNLEFIGGDMFESIPRADAIILKNVLHNWGDDESVKILKRCREAIPPKKEGGKVMVIEIVVEEDSKLENDQLTKTQLYFDMLMMTTFNGKERSEKQWEKLFLEAGFTDYKITPLMGFSSLIEAFP
>rna-gnl|WGS:MVGT|mrna.BVC80_9005g36
MEIQLGDQEQEMKWQGQVWNHICGSVDTAVLKCSIELGIFDIIHNSGKPMITLSELSTSPSLVSVKTENLYRLLRYLAHMNLITINSVEGNETFSLTNIAKLLLRNQEKSLVDWALGIGDEILMAVWHELSSSCSTPADGPTACQKVHSMGCYDLTEKNPKLNQVINNAMASDTRLVMPAFVQGCHEVLNGISSLVDIGGGIGTAMSYVVKAFPHIKCTAFDLPHVVATAPQYPGVDLVGGNMFEFIPPADAVLLKFMLHNWEDEECVKLLKRCKEAIPGDRGKVIIIEIVLDQDEDENDDDDDNYELIRARLSLDLDMMLSSGGRERTKDEWRVLLIEMAGFSRHEIIPICAIQSVIVAYP
>rna-gnl|WGS:MVGT|mrna.BVC80_9005g35
MEIQLGDQEQEMKWQGQVWNHICGSVDSAVLKCTIELGLLDIIHSSPKPITLSELSSSPSLSSLKAQNLYRLLRYLSHMNLITSNIVEGNETFSLTDLSKLLLKNQERSLKDWVLGIDDEHSINSWHELSSYCCSPDDAPTPFVKLHGKTLWELAEEVPEVNELINNGMACDTRMVMPAFIKGCEKILNGITKLVDIGGGTGAAISYVVKAFPQIKGTVFDLPHVVATAPEIPGVEMVGGDMFECIPSADALLLKFMLHNWKDDECIKLLKRCKETIPTDQGKVIIIEMVLDQDEDDDDLTQARLSLDLDMMLSSGGKERTKDEWRVLLETAGFSRIEFIPIFAIQSVIVAYP
>rna-gnl|WGS:MVGT|mrna.BVC80_9087g12
MEKVDGKRREEQEERLQGQADIWSHMFAFADSMALKCAVELGIPDIINSHGRPITISEITDAIITVSPVPSSSPDTNCLSRVMRLLVRKRIFSVQIHPESGQTLYGLTPSSKWLLKDSEFSLAPMVLAELHPWLISPWNYLSKCVQEGGIAFEKAHGSEIWDFALANQDFNKLFNGGMACTAKIVVNAILVNYKEGFDGVGSIVDVGGGTGMMIGEIVKAHPRIQGINFDLPHVVATAPECEGVAHVGGDMFVDIPHADAVIMKWIMHDWSDKDCVRILKNCRKAIPKETGKVIIFDCVLPPDGPDDKGGLFDNTRLVFDLLMIAHSSGGKERTEVEWKRLLKDGGFPSYKIIQIPALLSIIEAYPE
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University