Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Lunaria annua
Species name
Honesty (Lunaria annua) is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Lunaria_annua.HIDH.fa
Download
>Luann.0021s0131.1.v1.1
MDSEIAFDCSPVYRIYKSGRIERLLGETVVPPSLTPQNGVVSKDTVYSPEKNLSLRIYVPEKAIETSEKLPVLVYFHGGGFIIETAFSPTYHTFLTSAVAAADCLAISVDYRRAPEFPIPIPYEDSWDSLKWVFAHISEAGPENWINKHADFNKVFLAGDSAGGNIAHHITIRAKREKLDSAISGIILIHPYFWGKTPIDELETRDVTKRKKVERSWRIASPNSENGADDPLINVVGSGSSDLSGLGCGRVLVMVAGDDHFVRQGWGYAAKLEKSRWEGEVEVMEIENEAHVFHLKDPNTDNARKLVKKLAEFINN
>Luann.0028s0215.1.v1.1
MATISFSHKHQSSDNRRGGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVPPTVHPSAKVSAFDIKISNDTSTRVYIPVAAASPSVTLPLIVYFHGGGFCVGSVAWSCYHDFLTNLAVKASCVVVSVNYRLAPEHRLPAAYDDGVNVVSWLVKHQISNGDYSWVSKCNLSNVFLSGDSAGANIAYQVAGRITASGRYVNNLNLKGLILIHPFFGGESRTSSEKQHHTKSSALTLSASDTYWRLALPRGASRDHPWCNPLVSSAGFLREAKLPTTMVFMAESDILKDRNLEMCKVMRSHVKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMMCRLHNFINP
>Luann.0032s0322.1.v1.1
MAAISFSHNHHSSDNRRGGSQNYRHGPVVEEIEGVIKIFNDGCVERPPIVPIVSPTVHPSAKVTAFDIKLSNDTSTRVYIPDAAASSSVTLPLLVYFHGGGFCVGSAAWSCYHDFLTDLAVKARCIVVSVNYRLAPEHRLPAAYDDGVNVVSWLVNQQKSNGGHSWVSKCNLSNVFLGGDSAGANIAYQVAVRITANGKCVNNLNLEGIILIHPFFGGEPRTSSEKQHHSKSSALTLSASDTYWRLALPRGANREHPWCNPLANSAGFLRETKLPTTMMFMAEFDILKDRNLEICKVMRSHGKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMMCRLHNFIHP
>Luann.0035s0075.1.v1.1
MDSEIAFDHSPAYRVYKSGRVERLRGETIVPPSVIPQNGVVYKDAVYSPGKNLSLRIYLPEKASVTGKKLPVLVYFHGGGFIIENAFSPTFHTFLTSTVAAAECLAISVDYRRAPEFPIPIPYEDSWDSLKWVLAQSAGGNISHHLAIRAEREKLYPGISGIILIHPYFWGKTPIDELETKDVKERKLIEESWGIASPNSKDGTDDPLINVVGSESSDLTGLGCGRVLVMVAGDDTLVRRGLVYAAKLEKSGWEGEVEVMETKDETHVFHLNNPNSEKARLAVKKIAEFVNK
>Luann.0041s0103.1.v1.1
MDSEIVADYSPLLKVYKSGRIERLMGETTVPPSSVPLNGVVSKDVVYSPDNNLSVRIYLPEKAAAAKLPLLVYFHGGGFIIETAFSPTYHTFLTAAVSASDCVAVSVDYRRAPEHPIPIAYDDSWTALKWVFSHISGSGKEDWLNKHADFSKVFLAGDSAGANIAHHMAMKAAKEKLSPELSDSGISGIILIHPYFWSKTPIDEKETKDETLRSKIEAIWTMASPTSKEGSDDPLINVVQSESSDISGLGCGKVLVMVAEKDALARQGWGYAAKLEKCRWNGQVEVAESEGEDHVFHLMKPDCDKALEALHKFSAFLKGH
>Luann.0056s0019.1.v1.1
MDSTKKQVSLELFPWLVVHSDGTLERLAGTEICPPGLDQENRVLSKDIIIDPKTGLSARIYRPDPIQSGHKLPLVLYFHGGAFLISSASFPNYHTSLNKLVSQANIIAVSVNYRLAPEHPLPTAYEDSWTALETIQASNEPWINDYADFDRFFLVGDSAGANISHHLAFRVKQSNMTVKIKGIGMIHPYFWGSQPIGSEVNDEPRKKVVDGWWRFVCPSDKGSDDPWINPFVHGSPDLEGLGCERVMITVAEKDILRERGKMYYERLVKSKWRGKVEMMETKEKDHVFHIFEHDCVEAIEMLNRLAFFINQD
>Luann.0072s0094.1.v1.1
MESEIASEFLPFGRIYKDGRVERLTGTEIIPASLDLTNDVVSKDVVYSTEHNLSVRLFLPHKSTELVAGNKLPLLIYIHGGAWIIESPFSPIYHSYLTEVVKSANCLAVSVQYRRAPEDPIPAAYEDSWSAIQWIYSHSDGSGPEDWINKYADFGRVFLAGDSAGANISHHMAMRAGKENLDPRIKGILIVHPAFWGTDPVDEQDVQAREIRNGIAEVWEKIASPNSVNGTDDPLFNVVGSGSDFSGLGCEKVLVAVAGKDVFVRQGLGYAAKLEKSEWKGTVDVIEEEEEGHVFHLQNPNCEKACNFLKKFAEFIVG
>Luann.0101s0026.1.v1.1
MDSEIAFDYSPRFRVYKNGRIERLVTETSVPPSLNPENGVVSKDAVYSPEKNLSLRIYLPHKADKTGEKKKLPLLIYFHGGAFIMETAFSPVYHAFLTSAVSAAECIAVSVDYRRAPEHPIPIAYEDSWDAIKWIFTHIVGSGPEDWVNENADFSRVFIAGDSAGANIAHHMGIRAGKEKSESGNFKISGMALFHPYFLSKAPIEEKEEVGAVRYMEGLWKIASPNSVNGVDDPWINVVGSDLSGLGCGRVLVMVAGNDVLAKQGWVYAAKLEKSGWEGKVEVMETKDEDHVFHIRNPHSDNTRVLVQIFTKFLKDETS
>Luann.0147s0024.1.v1.1
MLRRITFSVRLTSPSSFVRFFHQFPRSYLPLSSSPTAIGVSGRHLHRLTTPTSLRLICSHSSSDLFSEYPPFVRIYKDGRVERLSGTEIVPASLTPKNGVVSKDVVYSSEHNLSARLFLPHKATEAAAGNKLPLLIYIHGRAWIVESPFSPIYHNFLTEVVKSANCLAVSIQYRLAPEHPVPAAYEDSWSAIQWIFSHSNGSGPEDWINKHADFDRVYLVGDSAGANISHHMAMRAGEEKLKPRIKGIAIMHPAFWGKDPIDEHDLQDREMRNQVAEVWEKIVSPNSVDGTDDPWFNVVGSGSNFSELGSERVLVAVAGKDLFVRQGLGYAAKLKKSEWEGDEVVVVEDEDEDHCFHLLNPNSENAPKFMKRFVEFISD
>Luann.0149s0018.1.v1.1
MGATTLTHVTTLNPNNTNIHGPVVDEVEGLIRVYKDAHVERSQLVPCVGPSLSLELDVACSDVHIDKSTNVWARLYVPIVTKSSVSKFPLLVYFHGGGFCVGSASWSCYHEFLARLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAILWLKKSRNDNLWTKLCDFGKIFLAGDSAGGNIAHHVAAILAADDLKPLKIQGMILIQPFFGGEARTESETRVGDTKSSVLTLAASDAWWRLALPRGANREHPYCKPVKIKSTVMRTLVCVAEMDLLMDRNMEMCDGYEKEIKRVVYRGVGHAFHILGGGSVVPGSAVRRTASSGIMDDWSLRLSRRCSHLCSDSYNAMCLLRSKR
MDSEIAFDCSPVYRIYKSGRIERLLGETVVPPSLTPQNGVVSKDTVYSPEKNLSLRIYVPEKAIETSEKLPVLVYFHGGGFIIETAFSPTYHTFLTSAVAAADCLAISVDYRRAPEFPIPIPYEDSWDSLKWVFAHISEAGPENWINKHADFNKVFLAGDSAGGNIAHHITIRAKREKLDSAISGIILIHPYFWGKTPIDELETRDVTKRKKVERSWRIASPNSENGADDPLINVVGSGSSDLSGLGCGRVLVMVAGDDHFVRQGWGYAAKLEKSRWEGEVEVMEIENEAHVFHLKDPNTDNARKLVKKLAEFINN
>Luann.0028s0215.1.v1.1
MATISFSHKHQSSDNRRGGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVPPTVHPSAKVSAFDIKISNDTSTRVYIPVAAASPSVTLPLIVYFHGGGFCVGSVAWSCYHDFLTNLAVKASCVVVSVNYRLAPEHRLPAAYDDGVNVVSWLVKHQISNGDYSWVSKCNLSNVFLSGDSAGANIAYQVAGRITASGRYVNNLNLKGLILIHPFFGGESRTSSEKQHHTKSSALTLSASDTYWRLALPRGASRDHPWCNPLVSSAGFLREAKLPTTMVFMAESDILKDRNLEMCKVMRSHVKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMMCRLHNFINP
>Luann.0032s0322.1.v1.1
MAAISFSHNHHSSDNRRGGSQNYRHGPVVEEIEGVIKIFNDGCVERPPIVPIVSPTVHPSAKVTAFDIKLSNDTSTRVYIPDAAASSSVTLPLLVYFHGGGFCVGSAAWSCYHDFLTDLAVKARCIVVSVNYRLAPEHRLPAAYDDGVNVVSWLVNQQKSNGGHSWVSKCNLSNVFLGGDSAGANIAYQVAVRITANGKCVNNLNLEGIILIHPFFGGEPRTSSEKQHHSKSSALTLSASDTYWRLALPRGANREHPWCNPLANSAGFLRETKLPTTMMFMAEFDILKDRNLEICKVMRSHGKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMMCRLHNFIHP
>Luann.0035s0075.1.v1.1
MDSEIAFDHSPAYRVYKSGRVERLRGETIVPPSVIPQNGVVYKDAVYSPGKNLSLRIYLPEKASVTGKKLPVLVYFHGGGFIIENAFSPTFHTFLTSTVAAAECLAISVDYRRAPEFPIPIPYEDSWDSLKWVLAQSAGGNISHHLAIRAEREKLYPGISGIILIHPYFWGKTPIDELETKDVKERKLIEESWGIASPNSKDGTDDPLINVVGSESSDLTGLGCGRVLVMVAGDDTLVRRGLVYAAKLEKSGWEGEVEVMETKDETHVFHLNNPNSEKARLAVKKIAEFVNK
>Luann.0041s0103.1.v1.1
MDSEIVADYSPLLKVYKSGRIERLMGETTVPPSSVPLNGVVSKDVVYSPDNNLSVRIYLPEKAAAAKLPLLVYFHGGGFIIETAFSPTYHTFLTAAVSASDCVAVSVDYRRAPEHPIPIAYDDSWTALKWVFSHISGSGKEDWLNKHADFSKVFLAGDSAGANIAHHMAMKAAKEKLSPELSDSGISGIILIHPYFWSKTPIDEKETKDETLRSKIEAIWTMASPTSKEGSDDPLINVVQSESSDISGLGCGKVLVMVAEKDALARQGWGYAAKLEKCRWNGQVEVAESEGEDHVFHLMKPDCDKALEALHKFSAFLKGH
>Luann.0056s0019.1.v1.1
MDSTKKQVSLELFPWLVVHSDGTLERLAGTEICPPGLDQENRVLSKDIIIDPKTGLSARIYRPDPIQSGHKLPLVLYFHGGAFLISSASFPNYHTSLNKLVSQANIIAVSVNYRLAPEHPLPTAYEDSWTALETIQASNEPWINDYADFDRFFLVGDSAGANISHHLAFRVKQSNMTVKIKGIGMIHPYFWGSQPIGSEVNDEPRKKVVDGWWRFVCPSDKGSDDPWINPFVHGSPDLEGLGCERVMITVAEKDILRERGKMYYERLVKSKWRGKVEMMETKEKDHVFHIFEHDCVEAIEMLNRLAFFINQD
>Luann.0072s0094.1.v1.1
MESEIASEFLPFGRIYKDGRVERLTGTEIIPASLDLTNDVVSKDVVYSTEHNLSVRLFLPHKSTELVAGNKLPLLIYIHGGAWIIESPFSPIYHSYLTEVVKSANCLAVSVQYRRAPEDPIPAAYEDSWSAIQWIYSHSDGSGPEDWINKYADFGRVFLAGDSAGANISHHMAMRAGKENLDPRIKGILIVHPAFWGTDPVDEQDVQAREIRNGIAEVWEKIASPNSVNGTDDPLFNVVGSGSDFSGLGCEKVLVAVAGKDVFVRQGLGYAAKLEKSEWKGTVDVIEEEEEGHVFHLQNPNCEKACNFLKKFAEFIVG
>Luann.0101s0026.1.v1.1
MDSEIAFDYSPRFRVYKNGRIERLVTETSVPPSLNPENGVVSKDAVYSPEKNLSLRIYLPHKADKTGEKKKLPLLIYFHGGAFIMETAFSPVYHAFLTSAVSAAECIAVSVDYRRAPEHPIPIAYEDSWDAIKWIFTHIVGSGPEDWVNENADFSRVFIAGDSAGANIAHHMGIRAGKEKSESGNFKISGMALFHPYFLSKAPIEEKEEVGAVRYMEGLWKIASPNSVNGVDDPWINVVGSDLSGLGCGRVLVMVAGNDVLAKQGWVYAAKLEKSGWEGKVEVMETKDEDHVFHIRNPHSDNTRVLVQIFTKFLKDETS
>Luann.0147s0024.1.v1.1
MLRRITFSVRLTSPSSFVRFFHQFPRSYLPLSSSPTAIGVSGRHLHRLTTPTSLRLICSHSSSDLFSEYPPFVRIYKDGRVERLSGTEIVPASLTPKNGVVSKDVVYSSEHNLSARLFLPHKATEAAAGNKLPLLIYIHGRAWIVESPFSPIYHNFLTEVVKSANCLAVSIQYRLAPEHPVPAAYEDSWSAIQWIFSHSNGSGPEDWINKHADFDRVYLVGDSAGANISHHMAMRAGEEKLKPRIKGIAIMHPAFWGKDPIDEHDLQDREMRNQVAEVWEKIVSPNSVDGTDDPWFNVVGSGSNFSELGSERVLVAVAGKDLFVRQGLGYAAKLKKSEWEGDEVVVVEDEDEDHCFHLLNPNSENAPKFMKRFVEFISD
>Luann.0149s0018.1.v1.1
MGATTLTHVTTLNPNNTNIHGPVVDEVEGLIRVYKDAHVERSQLVPCVGPSLSLELDVACSDVHIDKSTNVWARLYVPIVTKSSVSKFPLLVYFHGGGFCVGSASWSCYHEFLARLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAILWLKKSRNDNLWTKLCDFGKIFLAGDSAGGNIAHHVAAILAADDLKPLKIQGMILIQPFFGGEARTESETRVGDTKSSVLTLAASDAWWRLALPRGANREHPYCKPVKIKSTVMRTLVCVAEMDLLMDRNMEMCDGYEKEIKRVVYRGVGHAFHILGGGSVVPGSAVRRTASSGIMDDWSLRLSRRCSHLCSDSYNAMCLLRSKR
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University