Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Ammopiptanthus nanus
Species name
Ammopiptanthus nanus is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Ammopiptanthus_nanus.COMT.fa
Download
>EVM0004047.1_R0
MGSYSSEKENHVEITPTPQRDDTDTLSAMVLGANIVFPAALNAAIELNLFEIIAKESSPDSGGFMSALEIASKLPTTQHSDLPNRLDRLLRLLASYSLLTVSTRTNEDGNAVRVYGMSPSGKYFVYDENGDGYLASFTSFLCHAALLGVWLNFKEAIVDPEIDLFKKVHGTSKFEYFGKDSRINDVFNKAMADICTTHMKRILEIYTRFEGISTLVDVGGGTGQCLKMIISKYPSIKGINFDLPQVIENAPPFPGIEHVGGNMFEGVPQGDAIILKAICHNWSDEKCLEILSNCWKALPPNGKVIVGELILSEEPEPTIEYQNISILDNIMFITPGGRERTEKQYESLGKRAGFSRFQVVSRAFSIMGVMEFHK*
>EVM0025170.1_R0
MGESYFNKDHLFETSSQQTEDDACLSAMLLSTNLVYPAVLNAAIELNLFDIIAKATPPGASMSSSEIASMLPTQHSDLSNRLERMLRLLASYSLLTCSTRTNLHGSTERVYGLSQVGKYLVSDEIMGYLASFTTFIFCPALLPVWLNFKEAVVDADIDLFNKVHGITKYQYMEKDPKMNHIFNKAMADVCATEMKRILEIYTGFEGISILVDVGGGNGRNLKMIISNYPLIKGINFDLPQVIENAPPLPGIEHIGGDMFASVPQGDAIILKAVCHNWSDEKCLEFLRNCHKALSPNGKVIVVEFILPEEPEPTKESKLVSILDNLMFITVGGRERTQKQYENLCKLSGFSRFQVACRAFNSLGVMEFYK*
>EVM0021317.1_R0
MGSSGETQITPTHVSDEEANLFAMQLASASVLPMILKSAIELDLLEIIAKAGPGVNLSPIDIASQLPTNNPDAPIMLDRILRLLACYNILTCSVRTLHDGKVERLYGLAPVAKYLVKNEDGVSLSALNLMNQDKVLMESWYYLKDAVLEGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSTITMKKLLETYTGFEGLKSLVDVGGGTGAVVNMIVSKYPTIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKADAVFMKWICHDWSDEHCLKFLKNCYEALPDNGKVIVAECILPVAPDSSLATKGVVHIDVIMLAHNPGGKERTEKEFEALAKGAGFQGFRVLCSAFNTYVMEFLKKV*
>EVM0020400.1_R0
MLPLVASFSLLTCSIRTNEDGKSERVYALSPIGKCFAYDNDGGSTAPFATLIHRGMHDLWKNVKDTFVDGNDI*
>EVM0033602.1_R0
MSSNYEKNQLPTEEAKDDAYLSSLVLSGTQIFSAFLNVAVDLNLFEIIAKTSSGGSNISASEIASQLPNQHPDLANRLDRMLPLLASFSLLTCSIRTNQDGKSERVYALSPIGKCFAYDNDGGSTAPFATLICRGMHDLWKNVKDAYLDGNDICSEKVYGMPFYQYAETNKEVTDMFFKAMVHVTPLEVKMVLQIYDGFEGVSTLVDVGGGAGQALKLIISKYPTIKGINNDLPHVVQNAPPHPGIEHVGGDMFESVPNGDAIILKQVCHNWSDEKCVELLRNCHKALPQHGKVIILDVIMPEVPNSSTASKEAFLFNNLMFLVHGGKERTVKEFENLCRSSGFSRFHVACDDPRALSGVIEFHK*
>EVM0007420.1_R0
MEDDFDPKEKQLNQHKIAMEEKSFTYAMHLVNSSVLSMAMQSAIELGVFDIIDKAAFMQRTQMHAATMLDRVLRLLASHSVIDCTVIDDEKGPPPHLQRLYSMAPVTKYFACNGGGGSLGPLMVLTQDNAILDTYFSVQQCMANRASLIMKKILESYEGLEHINRLVDVGGGFGVSLNIITSMPSHSGHQFRLASGHRKCISLCVLHDWSDERCLNCYAAIPDEGKVIVVEGVLPFEPETTAVVKRRSEQEFMILAKGTGFCGIRYKCFVCDVWGNEVLQVDSGHIALNGHILTASICRTKKFIKYLFFTLQPLRITEKMRLS*
>EVM0014226.1_R0
MELGNSYVISMSLQSASKLGVFDVLQKAGPDRVLRLLASHSILKCTILPDDQNLGSFQMLYNMSPVAKFFARDSDGVSLGPLMVVHQDNILLQTWSQLKDAIRKGGVPFGRVHGTHAFEYTSLDSRFNQLFNTAMINHTTLVMKKVLECYKGFEDIKRLVDVAGGHGANLNLITSKYPHTQAINFICLMLISGVEHIGGDMFESVPKGEAIFMKWILHDWSDEYCLKLLKNCYDAIPDDGKVIVVDAVLPVIPETNAAWKAVSQMDRSEQEFMELATGAGFSGIRYECYVRNFWVVEFFK*
>EVM0017832.1_R0
MTILSSLSSPPDLVLPDSPAIVHRHPDLTSIVYPWRWRRTRQRGRVFGIHAGPGAKLSAKEIASQLSCENPEASFMLDRVLRLLASYSILKCTALPDDQNLGSFQMLYSMAPVAKFYARDSDGFSLGPLMALTQDKIFLQSWSQLKDAIREGGVPFDRVYGIHAFEYPSLDSRFNQVFNTAMINHTTIVMKQVLECYKGFEDIKRLVDVGGGLGVNINLITSKYPHIQAINFDLPHVIEHAPSYPGVEHVGGDMFESVPKGDAIFMKWILHDWSDEYCLKLLKNCYKAIPNDGKVIVVDSILPIVPETTTHAKNAFEFDLIMMTQNPGGKERTKQEFMELATGSGFSGIRFVCCVNAVWVMEFFKVSKSWSPSHLWRRSRDSPFPFLTMPHTPRT*
>EVM0016514.1_R0
MDTSLQSNGKLVNGEHKNIHKAEEAHVQVKQEDGFNSAMQWVGSIVLLMALRSAIELGVFEIIAKAGEGVKLSAKDIALQIGTNNAEAPTMLDRLLRLLASHSLLNCSVLEDTQKIGLPQSLYSLTPGSEYFVNDADGVSLGPVLALILDKVFYQSWTELGGAIREGGIPFNRVYGMHAFEYPSVDPRLNEVFNKAMINSTTITMKKILEFYNGFEHINRLVDVGGGLGGINFDLPHVIEHAPVYHVGGDMFQSVPTGDAIFMKWILHDWSDEHRLKLLKNCYKAIPDDGKVIMVDSILPIVPDRTAYAKNAFVSDLLMMTQNPGGKERTKQEFMELATRSGFSGIRFVCCVNGFWLRSLNSYKDNLPNAEYKKYLRAMGPQGKFVDRPFSLVH*
>EVM0003927.1_R0
MEESTDTRKQARLAILELANMISVPMSLNAVVRLNVADAIWQGGSNAPLSAAQILNLVLPSGDAENLQRILRMLTSYGVFEEHLSGGERKYSLTDVGKTLVTDDDGLSYAPYVLQHHQDALMRAWPLVHEAVVDPTKEPFERANGEAAYGYYLKQPEMNELMVKAMSGVSVPFMRAMLEGYDGFHGVERLVDVGGSGGDCLRMILQKHPNVKEGINFDLPEVVAKAPPIPGVTHVGGDMFKYIPQGDAIFMKWVLTTWTDEEIKQILHNCYKSLPQGGKLIACEPVLPEHSDDSHRTRALLEGDIFVMTIYRAKGKHRTEEQFKQLAISVGFPRFRSFHVDHFYTILEFQK*
MGSYSSEKENHVEITPTPQRDDTDTLSAMVLGANIVFPAALNAAIELNLFEIIAKESSPDSGGFMSALEIASKLPTTQHSDLPNRLDRLLRLLASYSLLTVSTRTNEDGNAVRVYGMSPSGKYFVYDENGDGYLASFTSFLCHAALLGVWLNFKEAIVDPEIDLFKKVHGTSKFEYFGKDSRINDVFNKAMADICTTHMKRILEIYTRFEGISTLVDVGGGTGQCLKMIISKYPSIKGINFDLPQVIENAPPFPGIEHVGGNMFEGVPQGDAIILKAICHNWSDEKCLEILSNCWKALPPNGKVIVGELILSEEPEPTIEYQNISILDNIMFITPGGRERTEKQYESLGKRAGFSRFQVVSRAFSIMGVMEFHK*
>EVM0025170.1_R0
MGESYFNKDHLFETSSQQTEDDACLSAMLLSTNLVYPAVLNAAIELNLFDIIAKATPPGASMSSSEIASMLPTQHSDLSNRLERMLRLLASYSLLTCSTRTNLHGSTERVYGLSQVGKYLVSDEIMGYLASFTTFIFCPALLPVWLNFKEAVVDADIDLFNKVHGITKYQYMEKDPKMNHIFNKAMADVCATEMKRILEIYTGFEGISILVDVGGGNGRNLKMIISNYPLIKGINFDLPQVIENAPPLPGIEHIGGDMFASVPQGDAIILKAVCHNWSDEKCLEFLRNCHKALSPNGKVIVVEFILPEEPEPTKESKLVSILDNLMFITVGGRERTQKQYENLCKLSGFSRFQVACRAFNSLGVMEFYK*
>EVM0021317.1_R0
MGSSGETQITPTHVSDEEANLFAMQLASASVLPMILKSAIELDLLEIIAKAGPGVNLSPIDIASQLPTNNPDAPIMLDRILRLLACYNILTCSVRTLHDGKVERLYGLAPVAKYLVKNEDGVSLSALNLMNQDKVLMESWYYLKDAVLEGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSTITMKKLLETYTGFEGLKSLVDVGGGTGAVVNMIVSKYPTIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKADAVFMKWICHDWSDEHCLKFLKNCYEALPDNGKVIVAECILPVAPDSSLATKGVVHIDVIMLAHNPGGKERTEKEFEALAKGAGFQGFRVLCSAFNTYVMEFLKKV*
>EVM0020400.1_R0
MLPLVASFSLLTCSIRTNEDGKSERVYALSPIGKCFAYDNDGGSTAPFATLIHRGMHDLWKNVKDTFVDGNDI*
>EVM0033602.1_R0
MSSNYEKNQLPTEEAKDDAYLSSLVLSGTQIFSAFLNVAVDLNLFEIIAKTSSGGSNISASEIASQLPNQHPDLANRLDRMLPLLASFSLLTCSIRTNQDGKSERVYALSPIGKCFAYDNDGGSTAPFATLICRGMHDLWKNVKDAYLDGNDICSEKVYGMPFYQYAETNKEVTDMFFKAMVHVTPLEVKMVLQIYDGFEGVSTLVDVGGGAGQALKLIISKYPTIKGINNDLPHVVQNAPPHPGIEHVGGDMFESVPNGDAIILKQVCHNWSDEKCVELLRNCHKALPQHGKVIILDVIMPEVPNSSTASKEAFLFNNLMFLVHGGKERTVKEFENLCRSSGFSRFHVACDDPRALSGVIEFHK*
>EVM0007420.1_R0
MEDDFDPKEKQLNQHKIAMEEKSFTYAMHLVNSSVLSMAMQSAIELGVFDIIDKAAFMQRTQMHAATMLDRVLRLLASHSVIDCTVIDDEKGPPPHLQRLYSMAPVTKYFACNGGGGSLGPLMVLTQDNAILDTYFSVQQCMANRASLIMKKILESYEGLEHINRLVDVGGGFGVSLNIITSMPSHSGHQFRLASGHRKCISLCVLHDWSDERCLNCYAAIPDEGKVIVVEGVLPFEPETTAVVKRRSEQEFMILAKGTGFCGIRYKCFVCDVWGNEVLQVDSGHIALNGHILTASICRTKKFIKYLFFTLQPLRITEKMRLS*
>EVM0014226.1_R0
MELGNSYVISMSLQSASKLGVFDVLQKAGPDRVLRLLASHSILKCTILPDDQNLGSFQMLYNMSPVAKFFARDSDGVSLGPLMVVHQDNILLQTWSQLKDAIRKGGVPFGRVHGTHAFEYTSLDSRFNQLFNTAMINHTTLVMKKVLECYKGFEDIKRLVDVAGGHGANLNLITSKYPHTQAINFICLMLISGVEHIGGDMFESVPKGEAIFMKWILHDWSDEYCLKLLKNCYDAIPDDGKVIVVDAVLPVIPETNAAWKAVSQMDRSEQEFMELATGAGFSGIRYECYVRNFWVVEFFK*
>EVM0017832.1_R0
MTILSSLSSPPDLVLPDSPAIVHRHPDLTSIVYPWRWRRTRQRGRVFGIHAGPGAKLSAKEIASQLSCENPEASFMLDRVLRLLASYSILKCTALPDDQNLGSFQMLYSMAPVAKFYARDSDGFSLGPLMALTQDKIFLQSWSQLKDAIREGGVPFDRVYGIHAFEYPSLDSRFNQVFNTAMINHTTIVMKQVLECYKGFEDIKRLVDVGGGLGVNINLITSKYPHIQAINFDLPHVIEHAPSYPGVEHVGGDMFESVPKGDAIFMKWILHDWSDEYCLKLLKNCYKAIPNDGKVIVVDSILPIVPETTTHAKNAFEFDLIMMTQNPGGKERTKQEFMELATGSGFSGIRFVCCVNAVWVMEFFKVSKSWSPSHLWRRSRDSPFPFLTMPHTPRT*
>EVM0016514.1_R0
MDTSLQSNGKLVNGEHKNIHKAEEAHVQVKQEDGFNSAMQWVGSIVLLMALRSAIELGVFEIIAKAGEGVKLSAKDIALQIGTNNAEAPTMLDRLLRLLASHSLLNCSVLEDTQKIGLPQSLYSLTPGSEYFVNDADGVSLGPVLALILDKVFYQSWTELGGAIREGGIPFNRVYGMHAFEYPSVDPRLNEVFNKAMINSTTITMKKILEFYNGFEHINRLVDVGGGLGGINFDLPHVIEHAPVYHVGGDMFQSVPTGDAIFMKWILHDWSDEHRLKLLKNCYKAIPDDGKVIMVDSILPIVPDRTAYAKNAFVSDLLMMTQNPGGKERTKQEFMELATRSGFSGIRFVCCVNGFWLRSLNSYKDNLPNAEYKKYLRAMGPQGKFVDRPFSLVH*
>EVM0003927.1_R0
MEESTDTRKQARLAILELANMISVPMSLNAVVRLNVADAIWQGGSNAPLSAAQILNLVLPSGDAENLQRILRMLTSYGVFEEHLSGGERKYSLTDVGKTLVTDDDGLSYAPYVLQHHQDALMRAWPLVHEAVVDPTKEPFERANGEAAYGYYLKQPEMNELMVKAMSGVSVPFMRAMLEGYDGFHGVERLVDVGGSGGDCLRMILQKHPNVKEGINFDLPEVVAKAPPIPGVTHVGGDMFKYIPQGDAIFMKWVLTTWTDEEIKQILHNCYKSLPQGGKLIACEPVLPEHSDDSHRTRALLEGDIFVMTIYRAKGKHRTEEQFKQLAISVGFPRFRSFHVDHFYTILEFQK*
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University