Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Luffa cylindnca
Species name
Species info
Gene sequence info
Luffa_cylindnca.HIDH.fa
Download
>Maker00000520
MNRDGPEPWLNEHADFNRVCLAGDSAGANICNYLASRAGSSAEQLGGVKLVAMALIHPFFGDGGENRQWKYLCPATSGDDDPRLKPAAEDLAKLPCGRVKIFLAEEDFLKVGAMKYDEDLKRCGWNGAVETVEHGGEDHVFHLKKPDCENAFDLTEKLASFISLH
>Maker00000820
MDSAAVAGEEVVFQFHPIFRVFKSGRVERFFPADRVPPSTDPLTGVQSKDVLIDPHTQLSVRIYLPQVSDSTNKLPLLIYIHGGAFAIGSVASPIYHRHLISLAAEANAVALSVEYRLAPEHPLPAAYEDAWAAVEWAASHSNRDGAETWLNEHADFDRVFVVGDSAGANISYNVVGRASDSENGPKGLNIIGLGLVHPFFMIDKADKLMEYIFPTSAGLEDPRMNPWVNPGLGRFGCNRVLILAAERDFLKDRARGFHAALRESGWEGSVEMVETEGEEHVFHLFNPDCEKAVALVKKVASFIQSA
>Maker00000748
MATSPPFEVDECRGVLRVFSDGSIFRSSNPSFIVPVLDDGSVLWKDLLFDPLNHLHLRLYKPAHSSSRLPLFFYIHGGGFCIGSRTWPNCQNYCFRLASQLPALVISPDYRLAPENRLPAAIDDGFAAVRWLQAQAGSDHPDPWLADAADFSRVFISGDSAGGNIAHHLAVGLGLGSPELAPIRVRGYVLLAPFFGGTVRTRSEAEGPREAFLNLELIDRFWRLSIPIGSSTDHPLVNVFGPSSRDLEAVEVDPILVVVGGADLLKDRAVEYAEKLKKQGKKIELVEFEGKQHGFFTIDPNSEASNELMLLLKQFIAQH
>Maker00001137
MASDEIAYNFSPMIIVYKDGRAHRLIGNDLTPPCLDPQTGVESKDVVISPETAVSARIYRPKPTPAQPHKLPLLFYIHGGGFCIESAFSPTYHRHLNSLVAKANIVAVSVEYRRAPEHLLPIAYEDSWAALKWVAAHSAGTGPEEWLNGIADLDRVYFAGDSAGANIAHHMAVRVGSDGLAGLNLRGLMLVHPYFWGGKLIGDEEKLDPSARLFIEKLWFLACPTISGLDDPIVNPEYDPKLGRLAAERVAVYVAEKDALKERGWFYRDCLKKSGWGGAVEVEETKGEGHVFHLMNPTTDVAADFVGKLAAFINGGQRQ
>Maker00000278
MPHSITLTILFLHIKVQGKFYSQKKKSSGEILLKKKKSSGENFYPSMASSTVNDVAHEFFPFLRIYKDGRIQRLMPASDIVPAGADDPKSGFRSKDVTISADPAVSARVFIPSSADPNQKLPLLLYVHGGGFCIESAFSCQYHSHVGSLAAKANAVAVSVEYRLAPEHPIPACYDDCWEALRWVAAHVNRSEVSI
>Maker00016746
MAAADSNDPELDVELLPYLKLYKNGVVERLIGTRVTPPGLDSQTGVDSKDIVIVPETGVSARLYRPTAVEPRRKLPLVVYFHGGAFVIASSAEPIYHNNCLIPLAAEVESVVVSVNYRLAPEHPLPAAYDDSWAALQWIAAQSQSSGDDADHEPWLKQLVDFEKVFLVGDSAGANISHHMALRAKNSDLAGKIKILGIALIQPYFWGQEPIGSEITEQEQKAQVDRWWNFVCPSDRGNDDLLINPFADGSPAIEGLAGEKAVVLVAEKDILRDRGKLYYENLETSEWKGKVEIFETEGEDHAFHILDPTSEKAKSLTKRLALFINED
>Maker00016878
MAMIGEAPGYLQVYSDGSVRRSIPEVVVSTAKQSSKNYKFKDVIIDPKRRVTGRLFLPDIADAPGRLPVLVYFHGGGFCIGSTTWIGYHNFLGDLAAAARTVILSVDYRLAPENRLPAAYEDCYSSLEWLGHQASSEPWLQNADPSRVFLSGDSAGGNIVHHVAVKTIKSNIPNLTIKGLLLIHPYFGSKKRTEKEKEEGAAGLVEMNDMFWRLSIPEGRDRDYFGCNYENAQVTKEEWSQFPNVVVFVAGLDFLKERGELYAKFLQQMKVKEVKLVEAADESHVFHVFHPESEATRLLQKQMSQFMKSN
>Maker00025384
MESGEAETVFELLPLLRVHKNGRIERLIGTDFVPPSTDPLTGVTSKDVTIFPEFGVSARPFLPNLTHPTQRLPLVVYFHGGCFCTQSPFTAKYHNYLNALTAEAKVVAVSVNYRKATEHPIPAAYEDSWAALQWTISHYDGKGPEIWLNKHADFSRVFLAGASAGANIAHNLAMVAGDPDCGVNIGLLGVALEHPYFWGSVRIGKEAGDPVRAGLFDRLWGFVCPARPDNDDPWVNSVAEGAARLAGMGSGRVLVCVAEKDVLRDRGWLYYHALGDSGWIGVAEIVETEDEDHMFHLNDLESQKAKDLIRRLGAFFNSDMAPPLPF
>Maker00033934
MTTEKSLILDVSGWLRLFDDGSVDRTWTGPPEVKFVAESVPPHEEFIDGVAVRDVVIDQKSGLRVRTYLPEVKCAGGKKLPVVVHFHGGGFCISEADWFMYYHTYTGLVRSAEAICVSVYLRRAPEHRLPAAIEDGLSALRWLRSVALGNEIEPWIVDNADFKRVFLIGDSSGGNLVHSVAALAGDADLAPLKLAGGIPIHPGFVRAKRSKSEMENPQSPFLTLDMVDKFLSLALPAGSSKDHPITCPMGTDAPPLESLDLPPFLLCIAEKDLVIDTEMEYYEAMKAANKEVEILMSKGMGHSFYLNKIALKIDPETAAESDRLFAGIARFIKQH
>Maker00010324
MPTINLDQIPSFEEHGNGFDQHDVLVEEIEGLIRVYGNGYVERAQIVPCVSNALPPEFGVTSWDVVVDKLNNIWARFYIPQQCQEKLPLLVYFHGGGFCVGSAAWSCYHEFLAKLSAKADCIIMSVNYRLAPENPLPAPYEDGLKTLSWLKQVALVGAKQNCAGGNIAFNVATRLGGKTTASGAVVLKPLVIKGNILIQPFFSGESRTKSEKFLVQPPRSPLTMAVSDTYWRLALPSGANRDHPWCNPSAKGLFKVEDLRVLPSLVCISEMDILKDRNLEFCSALHRDGKLINYVVYEGVGHAFQVLNKSQLSQTRTLEMIDHIKDFLSV
MNRDGPEPWLNEHADFNRVCLAGDSAGANICNYLASRAGSSAEQLGGVKLVAMALIHPFFGDGGENRQWKYLCPATSGDDDPRLKPAAEDLAKLPCGRVKIFLAEEDFLKVGAMKYDEDLKRCGWNGAVETVEHGGEDHVFHLKKPDCENAFDLTEKLASFISLH
>Maker00000820
MDSAAVAGEEVVFQFHPIFRVFKSGRVERFFPADRVPPSTDPLTGVQSKDVLIDPHTQLSVRIYLPQVSDSTNKLPLLIYIHGGAFAIGSVASPIYHRHLISLAAEANAVALSVEYRLAPEHPLPAAYEDAWAAVEWAASHSNRDGAETWLNEHADFDRVFVVGDSAGANISYNVVGRASDSENGPKGLNIIGLGLVHPFFMIDKADKLMEYIFPTSAGLEDPRMNPWVNPGLGRFGCNRVLILAAERDFLKDRARGFHAALRESGWEGSVEMVETEGEEHVFHLFNPDCEKAVALVKKVASFIQSA
>Maker00000748
MATSPPFEVDECRGVLRVFSDGSIFRSSNPSFIVPVLDDGSVLWKDLLFDPLNHLHLRLYKPAHSSSRLPLFFYIHGGGFCIGSRTWPNCQNYCFRLASQLPALVISPDYRLAPENRLPAAIDDGFAAVRWLQAQAGSDHPDPWLADAADFSRVFISGDSAGGNIAHHLAVGLGLGSPELAPIRVRGYVLLAPFFGGTVRTRSEAEGPREAFLNLELIDRFWRLSIPIGSSTDHPLVNVFGPSSRDLEAVEVDPILVVVGGADLLKDRAVEYAEKLKKQGKKIELVEFEGKQHGFFTIDPNSEASNELMLLLKQFIAQH
>Maker00001137
MASDEIAYNFSPMIIVYKDGRAHRLIGNDLTPPCLDPQTGVESKDVVISPETAVSARIYRPKPTPAQPHKLPLLFYIHGGGFCIESAFSPTYHRHLNSLVAKANIVAVSVEYRRAPEHLLPIAYEDSWAALKWVAAHSAGTGPEEWLNGIADLDRVYFAGDSAGANIAHHMAVRVGSDGLAGLNLRGLMLVHPYFWGGKLIGDEEKLDPSARLFIEKLWFLACPTISGLDDPIVNPEYDPKLGRLAAERVAVYVAEKDALKERGWFYRDCLKKSGWGGAVEVEETKGEGHVFHLMNPTTDVAADFVGKLAAFINGGQRQ
>Maker00000278
MPHSITLTILFLHIKVQGKFYSQKKKSSGEILLKKKKSSGENFYPSMASSTVNDVAHEFFPFLRIYKDGRIQRLMPASDIVPAGADDPKSGFRSKDVTISADPAVSARVFIPSSADPNQKLPLLLYVHGGGFCIESAFSCQYHSHVGSLAAKANAVAVSVEYRLAPEHPIPACYDDCWEALRWVAAHVNRSEVSI
>Maker00016746
MAAADSNDPELDVELLPYLKLYKNGVVERLIGTRVTPPGLDSQTGVDSKDIVIVPETGVSARLYRPTAVEPRRKLPLVVYFHGGAFVIASSAEPIYHNNCLIPLAAEVESVVVSVNYRLAPEHPLPAAYDDSWAALQWIAAQSQSSGDDADHEPWLKQLVDFEKVFLVGDSAGANISHHMALRAKNSDLAGKIKILGIALIQPYFWGQEPIGSEITEQEQKAQVDRWWNFVCPSDRGNDDLLINPFADGSPAIEGLAGEKAVVLVAEKDILRDRGKLYYENLETSEWKGKVEIFETEGEDHAFHILDPTSEKAKSLTKRLALFINED
>Maker00016878
MAMIGEAPGYLQVYSDGSVRRSIPEVVVSTAKQSSKNYKFKDVIIDPKRRVTGRLFLPDIADAPGRLPVLVYFHGGGFCIGSTTWIGYHNFLGDLAAAARTVILSVDYRLAPENRLPAAYEDCYSSLEWLGHQASSEPWLQNADPSRVFLSGDSAGGNIVHHVAVKTIKSNIPNLTIKGLLLIHPYFGSKKRTEKEKEEGAAGLVEMNDMFWRLSIPEGRDRDYFGCNYENAQVTKEEWSQFPNVVVFVAGLDFLKERGELYAKFLQQMKVKEVKLVEAADESHVFHVFHPESEATRLLQKQMSQFMKSN
>Maker00025384
MESGEAETVFELLPLLRVHKNGRIERLIGTDFVPPSTDPLTGVTSKDVTIFPEFGVSARPFLPNLTHPTQRLPLVVYFHGGCFCTQSPFTAKYHNYLNALTAEAKVVAVSVNYRKATEHPIPAAYEDSWAALQWTISHYDGKGPEIWLNKHADFSRVFLAGASAGANIAHNLAMVAGDPDCGVNIGLLGVALEHPYFWGSVRIGKEAGDPVRAGLFDRLWGFVCPARPDNDDPWVNSVAEGAARLAGMGSGRVLVCVAEKDVLRDRGWLYYHALGDSGWIGVAEIVETEDEDHMFHLNDLESQKAKDLIRRLGAFFNSDMAPPLPF
>Maker00033934
MTTEKSLILDVSGWLRLFDDGSVDRTWTGPPEVKFVAESVPPHEEFIDGVAVRDVVIDQKSGLRVRTYLPEVKCAGGKKLPVVVHFHGGGFCISEADWFMYYHTYTGLVRSAEAICVSVYLRRAPEHRLPAAIEDGLSALRWLRSVALGNEIEPWIVDNADFKRVFLIGDSSGGNLVHSVAALAGDADLAPLKLAGGIPIHPGFVRAKRSKSEMENPQSPFLTLDMVDKFLSLALPAGSSKDHPITCPMGTDAPPLESLDLPPFLLCIAEKDLVIDTEMEYYEAMKAANKEVEILMSKGMGHSFYLNKIALKIDPETAAESDRLFAGIARFIKQH
>Maker00010324
MPTINLDQIPSFEEHGNGFDQHDVLVEEIEGLIRVYGNGYVERAQIVPCVSNALPPEFGVTSWDVVVDKLNNIWARFYIPQQCQEKLPLLVYFHGGGFCVGSAAWSCYHEFLAKLSAKADCIIMSVNYRLAPENPLPAPYEDGLKTLSWLKQVALVGAKQNCAGGNIAFNVATRLGGKTTASGAVVLKPLVIKGNILIQPFFSGESRTKSEKFLVQPPRSPLTMAVSDTYWRLALPSGANRDHPWCNPSAKGLFKVEDLRVLPSLVCISEMDILKDRNLEFCSALHRDGKLINYVVYEGVGHAFQVLNKSQLSQTRTLEMIDHIKDFLSV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University