Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Luffa cylindnca
Species name
Species info
Gene sequence info
Luffa_cylindnca.CHS.fa
Download
>Maker00015145
MALPDEISSSAKESMDSQPHNERSISSILIIIAMQTEALPLVDKFQLTEDLNSVFPKEVPWVRYHGTCKGVDSVGTISASLVTYASIQAFRPDLIINAGTAGGFKAKGASIGDVFLVSECAFHDRRIPIPVFDLYGVGLKQALSTPRLLKELDLKVGKLSTGDSLDMSAQDEASIVANDATVKDMEGAAIAYVADLFKVPAIFVKAVTDIVDGEKPTAEEFLQNLATVSAALDQALEMKEMENRNGAQGASKGKANPGGATILALGKAFPPQLVLQDYLVDGYFKDTSCDDLDLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAMEGQATIKQRLEICNKAVTDMAIEASQAAIKNWGRPVSDITHLVYVSSSEARLPGGDLFLARGLGLGPHTQRLMLYFMGCSGGVAGLRVAKDLAENNPGSRVLLVTSETTIIGYKPPSAHRPYDLVGVALFGDGAGAMLVGTDPVLGIERPLFELHTATQKFIPNTQNIIDGKLSEEGISFTIGRELPQIIEDNIESFCEAFLQTVGLHEKEYNKIFWAVHPGGPAILNRLEKRLELLPEKLTASRRALMDYGNASSNTIVYVLEYMMEESLKMKMGGGEIEEWGLILAFGPGISFEGILARNLAV
>Maker00008699
MECKMFEKLEANQKPRSRATILGIGTAVPSYCYYQSQFPDFYFGATNSQHMMQLKQKFKNICEKSHIRKRYLHLNEEILKANSNMCKYGAPSLDARQEMMEEEVPKLGKEAALKAIEDWGQPISNITHLIFCTSSSNSTPGPDCHLSKLLGLKPSIQKFMLYQQGCFVAGTALRLAKDVAENNVGARVLVVCADITTICFHAPTESQLDLLVGHAIFSDGAAAMVVGADPNIAIERGLFEIVSASQTLLPNTEDGIRLTIKEMGLLYRLSRNVPKYVGENIEKCLGDAIPSGISDYNSLFYAIHPGGRAILDEIEKKLGLEEDKLEVSRYVLREHGNMIGATVGFVLDEMRKKSIREGKSTTGEGLECGVLVTLGPGLTIETLILQSVPIVQV
>Maker00008723
MVSKMFEKREANQRRATILGIGTALPPNCLYQSRYPDFYFGVTNNQHMTELKQKLQNICEKSHIKKRYFHTNEEILKANPSMCKFGAPSWDARLEMMREEVPKLGKEAALKAIEDWGQPISNITHLIFCTSSSNSMPGPDCQLAKLLGLRPSIGKYMLFQHGCYAAGTALRLAKDVTENNVGARVLVVCVDITTICFHGPPENRLDILVGQAIFSDGAAALVVGANPDAAIERGLFEIVSASQALLPDTEDGVNAIIKEMGLLYHLSRNIPKYVGENIENCLADAWPSGIDDYNSLFYIIHPGGRAILDAIEQKLELEEGKLEVSRYVLREYGNMAGPTVIFVLDEMRKKSIREGKSTTGEGLECGVLVAIGPGLTLETLMLQSVPILKIT
>Maker00008439
MCKYGAPSLDARQEMMEEEVPKLGKEAALKAIEDWGQPISNITHLIFCTSSSNSTPGPDCHLSKLLGLKPSIQKFMLYQQGCFVAGTALRLAKDVAENNVGARVLVVCVDMSTIFFHAPTENRLDILVAHAIFSDGASAMMRNRITGENRGRPEAEGTKRSRTGSARASGPTMSLGLSLGPRLSRGSSQKPDLFCLGPSHLPVSPLGSISQPDFSPVVLVSSLYIGVVVGANPDVIVERGLFEIVSASQALLPNTEDGIKVIVKEMGCLYQLSRNIPKYVGGNIKKCLGDAIPSGINEYNSLFYAIHPGGRAVLDEIEQKLGLEKGKLEVSRHVLREYGNMMGPTVGFVLDETRKKSIREGKSTTGEGLKCGVLVTLGPGLTMETLILHSVPIAQV
>Maker00008463
MPGHDCQVAKLLGLRPSIGKYMFQHGCYAAGTALRLAKDVAENNAGARVLVVCADITTIRFHGPPENHFDILVGQAIFSDVGANPDAAIERGLFEIVSASQVLVPNTEDGAISIIKEMGLLYHLSRNIPKYVGENIENCWVNAWPSGIGDYNSLFYIIHPGGRAILDAIEQKLQLEESKLKVSRHVLREYGNMIGPITVVFVLDEMRKKSIREGKSTTGDRLERGVLVTFGPGFTLETLMLQSVPILKT
>Maker00008481
MAFEMGEKQEMRATILSIGTVVPTNCIYQTQYPDLYFRVTHSLHMTHLKQKFHNICKKSGIHKRYFHLNEEILRANPNICKYGAPSLDARQEMMEEEVPKLGKEAALKAIEEWGQPISNITHLIVSTSSSNCMPGVDTQLSNLLGLKPSVKKFMLFQIGCHSAGSALRLAKDVVENINNVGARVLVVSIDITTLYFHAPSETHLDILVGQAIFSDGAAAMIIGANPNATIERGLFQIVLASQTLIPNSKDGVIGNLREMGLSYHLSRNVPKYIGQNIKKCLVDATTGIIGDFNSLFYAIHPGGRAILDEIEANLALGEGKLEASRHVLHEYGNMGGPTVVFVLDEMRKKSMRQGKSNTGEGLKWGVLITFGPGITMEILMLQSLPLNQA
>Maker00001799
MTRPSNLPALLLNANSLCIPISQHNPSTLSILSNMASVALDQIRKAQRAEGPATVLAIGTATPPHSVLQSDYPDYYFRITNSEHMTHLKDKFARMCEKSMIRKRHMYLTEEILRENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAAKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLLKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSETHLDSMVGQALFGDGAGAVIIGSDPDLAMERPLYELVWTGATILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFTPLGISDWNSIFWIAHPGGPAILDQVEAKLGLKEEKMRATREILSEYGNMSSACVLFIMDQMRKNSMEEGNSTTGEGLEWGVLFGFGPGLTVETVVLHSVHINETAVNGTAHSTTTPAEVVVTN
>Maker00031981
SKALAVYHTIHLPVVAFSAAINPTGDWFILSENLPFALALRTSTACEIKSIGYIPMAAISSYKDRAMFLFKGQSLNLHRRLPALRCYSSQLTKTETKSSTKTKKARDMARMINYKPWSNDLQSSLASLSPSLSKTTVLQTLGFLRDPSKALQFFNWAQEMGYAHTEQSYFSMLEILGRNRHLNTARNFLFSIEKRSRGAVKLEARFFNSLMRNFSRAGLFQESIKIFTTMKSHGVSPSVVTFNSLLSILLKRGRTNMAKNVYDEMLSTYGVTPDTFTFNILIRGFCMNGMVDEGFRIFKDLSRFGCEPDIITYNTLVDGLCRAGKVTIAYNVVKGMGKKSVDLNPNVVTYTTLIRGYCAKREIDRALVVFEEMVSLGLKANNITYNTLIKGLCEAHKFEKIKEILEATAGDGTFSPDTCTFNTLMHCHCDAGKLDEALRVFERMTELKIQPDSATYSVLVRSLCQGGHYEKAEELLDKLLEREILLSGNGCKPLVAAYNPIFKYLCENGKTKKAEKVFRQLMRRGTQDPPSYKTLIMGHCNEGTFESGYELLVLMLRKDFLPDLEIYESLIDGLLHKDKPLLALQTLEKMLRSSHLPKSSTFHSILAKLLEHGSASESASLIQVMLDKNIRQNLSFSTGCIRLLFGAGMNDKAFQIVRLLYENGYSVRMEELIHYLCHCKKVIDASKMLLFSLESHQSVDMDVCNLVIFHLCEINKLAEAFSLYYKLVEMGVHQQLSCQNQLKVSLEAGGKLEEAAFVSKRMEPPPKFKNSNPQNILQSSLQGLSQSERWRGIWTLKREDEIWNHEGYVLKDLEHGNFKDGITAPEREPKEICRRSLQTKTINILLKLPNTSKMSCEGLAKLDHARARRVPTPGKATILAIGKAFPSQLVPQECLVEGYIRDTKCFDATIKEKLERLCKTTTVKTRYTVMCKEILDKYPELVTEGSPTIRQRLEIANPAVVEMATEASKACIKEWGRSVEDITHIVYVSSSEIRLPGGDLYIANRLGLKNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNNARPYDLVGAALFGDGAAAAIIGADPVPGQESPFMELNYAIQQFLPDTHGVIDGRLSEEGINFKLGRDLPQRIDDNIEEFCRKLMGKGKLVDFNDMFWAVHPGGPAILNKLESTLRLKSEKLECSRKALMDYGNVSSNTIFYVIENMRENLKREDGEEWGLALAFGPGITFEGILIRSL
>Maker00023312
MTTIDEILKARRVEGPATVMAIGTAVPPNCIEQSTYPDYYFRITNSEHNIELKQKFNRMCEKSTIEKRYMLLTEELLKQNPKLCAYEAPSLDLRQDIAVVEVPKLGKQAAVNAIREWGRPTADITHLIFCTSSGVDMPGADYRLTKLLGLRPSVKRFMIYQQGCFAGATVLRLLKDLAENNRSARVLAVCSEITAVTFRGPSASHLDSLVGQALFSDGAAAIIVGSDPLPGLERPIFEIISAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLVSNNIERLLLEAFGPLGLSDWNSIFWIAHPGGPAILDRIEIELGLGPEKLRSSRHVLREYGNMSSACVLFILDEMRKKSKENGLRTTGDGLEWGVLFGFGPGLTVETVVLRSVPI
MALPDEISSSAKESMDSQPHNERSISSILIIIAMQTEALPLVDKFQLTEDLNSVFPKEVPWVRYHGTCKGVDSVGTISASLVTYASIQAFRPDLIINAGTAGGFKAKGASIGDVFLVSECAFHDRRIPIPVFDLYGVGLKQALSTPRLLKELDLKVGKLSTGDSLDMSAQDEASIVANDATVKDMEGAAIAYVADLFKVPAIFVKAVTDIVDGEKPTAEEFLQNLATVSAALDQALEMKEMENRNGAQGASKGKANPGGATILALGKAFPPQLVLQDYLVDGYFKDTSCDDLDLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAMEGQATIKQRLEICNKAVTDMAIEASQAAIKNWGRPVSDITHLVYVSSSEARLPGGDLFLARGLGLGPHTQRLMLYFMGCSGGVAGLRVAKDLAENNPGSRVLLVTSETTIIGYKPPSAHRPYDLVGVALFGDGAGAMLVGTDPVLGIERPLFELHTATQKFIPNTQNIIDGKLSEEGISFTIGRELPQIIEDNIESFCEAFLQTVGLHEKEYNKIFWAVHPGGPAILNRLEKRLELLPEKLTASRRALMDYGNASSNTIVYVLEYMMEESLKMKMGGGEIEEWGLILAFGPGISFEGILARNLAV
>Maker00008699
MECKMFEKLEANQKPRSRATILGIGTAVPSYCYYQSQFPDFYFGATNSQHMMQLKQKFKNICEKSHIRKRYLHLNEEILKANSNMCKYGAPSLDARQEMMEEEVPKLGKEAALKAIEDWGQPISNITHLIFCTSSSNSTPGPDCHLSKLLGLKPSIQKFMLYQQGCFVAGTALRLAKDVAENNVGARVLVVCADITTICFHAPTESQLDLLVGHAIFSDGAAAMVVGADPNIAIERGLFEIVSASQTLLPNTEDGIRLTIKEMGLLYRLSRNVPKYVGENIEKCLGDAIPSGISDYNSLFYAIHPGGRAILDEIEKKLGLEEDKLEVSRYVLREHGNMIGATVGFVLDEMRKKSIREGKSTTGEGLECGVLVTLGPGLTIETLILQSVPIVQV
>Maker00008723
MVSKMFEKREANQRRATILGIGTALPPNCLYQSRYPDFYFGVTNNQHMTELKQKLQNICEKSHIKKRYFHTNEEILKANPSMCKFGAPSWDARLEMMREEVPKLGKEAALKAIEDWGQPISNITHLIFCTSSSNSMPGPDCQLAKLLGLRPSIGKYMLFQHGCYAAGTALRLAKDVTENNVGARVLVVCVDITTICFHGPPENRLDILVGQAIFSDGAAALVVGANPDAAIERGLFEIVSASQALLPDTEDGVNAIIKEMGLLYHLSRNIPKYVGENIENCLADAWPSGIDDYNSLFYIIHPGGRAILDAIEQKLELEEGKLEVSRYVLREYGNMAGPTVIFVLDEMRKKSIREGKSTTGEGLECGVLVAIGPGLTLETLMLQSVPILKIT
>Maker00008439
MCKYGAPSLDARQEMMEEEVPKLGKEAALKAIEDWGQPISNITHLIFCTSSSNSTPGPDCHLSKLLGLKPSIQKFMLYQQGCFVAGTALRLAKDVAENNVGARVLVVCVDMSTIFFHAPTENRLDILVAHAIFSDGASAMMRNRITGENRGRPEAEGTKRSRTGSARASGPTMSLGLSLGPRLSRGSSQKPDLFCLGPSHLPVSPLGSISQPDFSPVVLVSSLYIGVVVGANPDVIVERGLFEIVSASQALLPNTEDGIKVIVKEMGCLYQLSRNIPKYVGGNIKKCLGDAIPSGINEYNSLFYAIHPGGRAVLDEIEQKLGLEKGKLEVSRHVLREYGNMMGPTVGFVLDETRKKSIREGKSTTGEGLKCGVLVTLGPGLTMETLILHSVPIAQV
>Maker00008463
MPGHDCQVAKLLGLRPSIGKYMFQHGCYAAGTALRLAKDVAENNAGARVLVVCADITTIRFHGPPENHFDILVGQAIFSDVGANPDAAIERGLFEIVSASQVLVPNTEDGAISIIKEMGLLYHLSRNIPKYVGENIENCWVNAWPSGIGDYNSLFYIIHPGGRAILDAIEQKLQLEESKLKVSRHVLREYGNMIGPITVVFVLDEMRKKSIREGKSTTGDRLERGVLVTFGPGFTLETLMLQSVPILKT
>Maker00008481
MAFEMGEKQEMRATILSIGTVVPTNCIYQTQYPDLYFRVTHSLHMTHLKQKFHNICKKSGIHKRYFHLNEEILRANPNICKYGAPSLDARQEMMEEEVPKLGKEAALKAIEEWGQPISNITHLIVSTSSSNCMPGVDTQLSNLLGLKPSVKKFMLFQIGCHSAGSALRLAKDVVENINNVGARVLVVSIDITTLYFHAPSETHLDILVGQAIFSDGAAAMIIGANPNATIERGLFQIVLASQTLIPNSKDGVIGNLREMGLSYHLSRNVPKYIGQNIKKCLVDATTGIIGDFNSLFYAIHPGGRAILDEIEANLALGEGKLEASRHVLHEYGNMGGPTVVFVLDEMRKKSMRQGKSNTGEGLKWGVLITFGPGITMEILMLQSLPLNQA
>Maker00001799
MTRPSNLPALLLNANSLCIPISQHNPSTLSILSNMASVALDQIRKAQRAEGPATVLAIGTATPPHSVLQSDYPDYYFRITNSEHMTHLKDKFARMCEKSMIRKRHMYLTEEILRENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAAKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLLKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSETHLDSMVGQALFGDGAGAVIIGSDPDLAMERPLYELVWTGATILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFTPLGISDWNSIFWIAHPGGPAILDQVEAKLGLKEEKMRATREILSEYGNMSSACVLFIMDQMRKNSMEEGNSTTGEGLEWGVLFGFGPGLTVETVVLHSVHINETAVNGTAHSTTTPAEVVVTN
>Maker00031981
SKALAVYHTIHLPVVAFSAAINPTGDWFILSENLPFALALRTSTACEIKSIGYIPMAAISSYKDRAMFLFKGQSLNLHRRLPALRCYSSQLTKTETKSSTKTKKARDMARMINYKPWSNDLQSSLASLSPSLSKTTVLQTLGFLRDPSKALQFFNWAQEMGYAHTEQSYFSMLEILGRNRHLNTARNFLFSIEKRSRGAVKLEARFFNSLMRNFSRAGLFQESIKIFTTMKSHGVSPSVVTFNSLLSILLKRGRTNMAKNVYDEMLSTYGVTPDTFTFNILIRGFCMNGMVDEGFRIFKDLSRFGCEPDIITYNTLVDGLCRAGKVTIAYNVVKGMGKKSVDLNPNVVTYTTLIRGYCAKREIDRALVVFEEMVSLGLKANNITYNTLIKGLCEAHKFEKIKEILEATAGDGTFSPDTCTFNTLMHCHCDAGKLDEALRVFERMTELKIQPDSATYSVLVRSLCQGGHYEKAEELLDKLLEREILLSGNGCKPLVAAYNPIFKYLCENGKTKKAEKVFRQLMRRGTQDPPSYKTLIMGHCNEGTFESGYELLVLMLRKDFLPDLEIYESLIDGLLHKDKPLLALQTLEKMLRSSHLPKSSTFHSILAKLLEHGSASESASLIQVMLDKNIRQNLSFSTGCIRLLFGAGMNDKAFQIVRLLYENGYSVRMEELIHYLCHCKKVIDASKMLLFSLESHQSVDMDVCNLVIFHLCEINKLAEAFSLYYKLVEMGVHQQLSCQNQLKVSLEAGGKLEEAAFVSKRMEPPPKFKNSNPQNILQSSLQGLSQSERWRGIWTLKREDEIWNHEGYVLKDLEHGNFKDGITAPEREPKEICRRSLQTKTINILLKLPNTSKMSCEGLAKLDHARARRVPTPGKATILAIGKAFPSQLVPQECLVEGYIRDTKCFDATIKEKLERLCKTTTVKTRYTVMCKEILDKYPELVTEGSPTIRQRLEIANPAVVEMATEASKACIKEWGRSVEDITHIVYVSSSEIRLPGGDLYIANRLGLKNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNNARPYDLVGAALFGDGAAAAIIGADPVPGQESPFMELNYAIQQFLPDTHGVIDGRLSEEGINFKLGRDLPQRIDDNIEEFCRKLMGKGKLVDFNDMFWAVHPGGPAILNKLESTLRLKSEKLECSRKALMDYGNVSSNTIFYVIENMRENLKREDGEEWGLALAFGPGITFEGILIRSL
>Maker00023312
MTTIDEILKARRVEGPATVMAIGTAVPPNCIEQSTYPDYYFRITNSEHNIELKQKFNRMCEKSTIEKRYMLLTEELLKQNPKLCAYEAPSLDLRQDIAVVEVPKLGKQAAVNAIREWGRPTADITHLIFCTSSGVDMPGADYRLTKLLGLRPSVKRFMIYQQGCFAGATVLRLLKDLAENNRSARVLAVCSEITAVTFRGPSASHLDSLVGQALFSDGAAAIIVGSDPLPGLERPIFEIISAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLVSNNIERLLLEAFGPLGLSDWNSIFWIAHPGGPAILDRIEIELGLGPEKLRSSRHVLREYGNMSSACVLFILDEMRKKSKENGLRTTGDGLEWGVLFGFGPGLTVETVVLRSVPI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University