Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Lonicera japonica
Species name
Japanese honeysuckle (Lonicera japonica) is a species of eudicot in the family Caprifoliaceae (honeysuckle famly).
Species info
Gene sequence info
Lonicera_japonica.HIDH.fa
Download
>Lj2A833G32.1
MATTSTEATPYEVDECRGVLRVYSDGSIVRSAKPSFDFPVHDDGSVLWKDVVFDPINNLQLRLYKPAAATTKLPIFYYIHGGGFCIGSRTWPNFQSYCFQLALELQAVVVAPDYRLAPENRLPAAIEDGFMAMKWLQGQAEMKEGMSGLLRWLTLRSTTTNVANFVKCLYLILLFSYDELCRYWRLSIPLGETTDHPLINPFGPASPSLENVDLDPILVVVGGSDLLKDRVEDYAKRLEAWGKKIEYVEFKGQQHGFVTINPHTLPADELMLIIKRFITQYST
>Lj2A833T32.1
MATTSTEATPYEVDECRGVLRVYSDGSIVRSTKPSFNVPVHDDGSVLWKDTVFDPINNLQLRLYKPAAATTKLPIFYYIHGGGFCIGSRTWPNCQNYCFQLALKLQAVVVAPDYRLAPENRLPAAIEDGFVAMKWLQGQAEMEENDKWLTEVADFGRVFVSGDSAGGNIAHHLAVQLGPGSVQLGPVRVKGFWTLSIPLGETTDHPLINPFGPVSPSLENVNFDPILVVVGGSDLLKDRAKDYAKKLKVWGKEDRVC
>Lj3C1018T4.1
MGITTLDPSLSYQITKVPQQHNGVVIEEIDGLIRVYKDGHVERPQIVPCVTSALAPEFNVTSRDIVIDKYTNIWARFYVPKCQSKLPLLVYFHGGGFCVGSATWSCYHNFLARLSAIARCIIMSVNYRLAPEHPLPAAYDDGFKALVWLKQQAISGPSEGF
>Lj3C740T7.1
MASSNNEIVTDFFPVLRIFKNGTVERIFGSPYVPPSPKDPTTGVSSKDISISPEISARIYLPPGASSKLPVLVYFHSGAFCVESAFSAAHHAYLNAIVSESRAVAISVEYRSAPEHPLPAAYEDCWTAIQWVGSHSTTTPHTTISVLEPWITNFGDFNRIYIGGDSAGGNIVHNILLRAGNDQLCGNMKIKGAFLSHPYFWGSEPLKGESGEESLAHKLWMFVNPSAAGGIDDPAINPFVGPSLKGLRCSRLLVCVSEKDELRERGVKYCEVVRESGWEGEVELVQVEGEDHCFHIFRADCDKARNLIKKLASFIV
>Lj3C740T6.1
MLFVLLFYSINFGRLEPWITNFGDFNRIYIGGDSAGGNIVHNILLRAGNDQLCGNIKIKGAFLSHPYFWGSEPLKGESGKESLAHKLWMFVNPSAAGGIDDPAINPFTGPSLKGLRCSRLLVCVSEKDELRERGVKYCEVVRESGWEGEVELVQVEGEDHCFNIFRADCDKARNLTKKLASFIV
>Lj3C740T5.1
MASSNNEIVTDFFPILRIYKDGTVERIFGSPYVPPSPKDPTTGVSSKDISISPEISARLYLPPAASSKLPVLVYFHGGAFCVESAFSAAHHAYLNAIVSESRAIAISVEYRSAPEHPLPAAY
>Lj4A53T54.1
MDSSKSEIAHDVPPYLTVYKDGTIQRHFGEEIAPASLDAATGTLSKDLLIVPETGVHARLYRPNISTDQRLPLVVYFHGGAFCISSAFDPKYHHSLNKLVAESNIVIVSVNYRLAPEHPLPAAFQDSWAALHWVASHASGGGSEAWLSAVDFSKVFLAGDSAGATISHHMAMRVADPDHNIGLKVHGILMIHPYFWGKEPIGSEVTDTARKAMVDTWWEFVCPSDKGHDDPLINPFADGAPDVTGLGCERIIVCVAEMDILRDRGRDYYERVVKSGWKGVAEMVEVEGEDHVFHILNPDGEKAVNMIKRLATFINQ
>Lj5A207T80.1
MASIIPELAYELPPFFKVYKDGKIERLMGTDIIPPGTDPETGVQSKDIVISPETGVSARLYKPKQTNQNQKVPLIIYFHGGGFYVQTPFSSTYQPFLNSLVAESNIIIVSVDYRKAPEHPLPIGYDDCWASIKWVASHSNCGGPEEWINEYANLECTFIMGDSAGANIAHNMAVRVGLDKPSGATIQGLILMHPYFWGKDPVGSESGDVETRSIIENYWKLACPRNSSADDPLMNPKMDPNLARLGCGRVLVFAAEIDFLRCRAWFYHETLMKSGWGGSAEIMESEGEEHVFHLYRPHCEKAIVLRKRVVSFINNTEKTISS
>Lj5A207T79.1
MDSEVTHDYHPFFRVYKDGHIERFIGTPFVPASDDSTVAVRSKDVVISNEPKVSARIFLPKTVTPNQKLPLLVYVHGGAFSIESAFSSLYYHYLTSLVADSNVVVVSVEYRLAPEHPIPACYDDTWTAMEWTARHSNGQGPDLWLNEHADFNRVFVAGDSAGANISHNVMVKYSNEGLGSVKILGMVLVHPYFGNKKPAKLWEYICPDSTGLDDLRLNPAAHPGLLAKLGKIRVLICTAENDHLRDRGWDYYEGLKKSGWGGEVEIVETEGEDHVFHLFNPKCEKAGVLMKLVTSFLNENKVDGSIGIMNTPVGSSLNQSNASSLL
>Lj6A597T90.1
MASTPTKEIATEILPAIRVYKDGTVERLLGSPFAPPSPQDPTTNVSSKDITISPQFSARLYLPKLTTAHKQKSLPILVYFHGGGFCIESAFSVAHHAYINSLVGESRAIAVSVEYRRVPEHLLPAAYEDCWNALQWVASHSVVNQNLEPEPWIVDFGDFNRVYIGGANIVHNIALRAGTEPINNDVKIKGAFLAHPYFSGSKQLAKETHNPNDENSLGYKLWTLAYPTAPGGIDNPMINPFGANAPSLRGLGCSRLLVCVAEKDGLRERGVGYYEGVKESGWNGEIELFEGLGEEHCYHVLKPGTLSTRDLIKRLASFIVV
>Lj6A597T89.1
MASNKKEVATELLPVLRVYKDGTVDRLYPDPQAPPSPLDPATGVSSKDIMISPEANVVAVSVGYRLAPEHPLPAAYEDCWTGLQWVASHADHDTIILDKEENKVEPEPWLINHGDFDRVYLGGDSAGGSEPMENHKESLLYRFWMLAYPNAPGGIDNPMINPWAPGGPDLSRIGCGRLFVCIGEKDKLRERGFRYCEAVRESGWKGELEFVEVEGEDHIFHIFKPHSDKAKSLIKRMASFIV
>Lj8C695T12.1
MPIIAEAPDYIRVFSDGSVKRFDHLTAPPSNVSINGFKSKDLTIDHSKPITARIYLPDTPKPDNRLPVLVYFHGGGFCVGSTTWLGYHHFLGGLSFESQSIVLSIDYRLAPENRLPAAYDDCYSSLEWLSHHANSEPWLERADLSHVFLSGDSAGGNIAHQTTLRAVRSQVNLVSIKGLMPIHPYFGSQNRTNLEKSNLDSFDVTMNDLFWNLSLPEGSNRDYFGCNFEKEVVTVEEWQRFPAVVVYVAELDFLKERGVMYFQFLKKNWVKDVKLVEAEGETHVYHVYRPLSEAAKVLQKQMSEFIHSI
>Lj8C102T3.1
MTFKTHKLFPSLFILISLTSNSIAHNQTNSDNQFLCSNGKQNPRTAPPPFLWTPALVQTKDIQIQPATGLSGRLYLPKFGAIPFTDLPLIIYFHGGGAFCSGSAYSLPYHKFSLRLAARSMSIILSVQYRSAPAHSIRVGYDDSWTALKWVASHSNSGRGLAPGHDPWIKHHTNFNRVFLAGDGVGANIAHTMGIRVGLENLGGVNISGVILIHPLLWGEKVKLDNEWGERRKVIYGVKDSAREWVSHLWSFVCPSSSGLGDPSVNPALDPDLRRMGCKRVVVFVAGDDPVAKGNYGYVAALRRSGWKGVVEIVKSKGKKNGFYLDPKYDISTEAINLMKKVVSFISHSRKAYNGTV
>Lj8P715T22.1
NARIFLPDTPKPNNHLPILVYFHGGGFCVGSTISLGYHHFLGALPVESQSIVPSIDYWLAPENRLPAAYDDCYSSLEWLSHQASCEPWLEQANLSRVFLSSDSAGGKIAHQTALRAVQSQVNCVSIKGLMLIHLYFGSQNRTNLEKSNPESFDVTMSDL
>Lj8P695T59.1
NARIFLPDTPKPNNHLPILVYFHGGGFCVGSTISLGYHHFLGALPVESQSIVPSIDYRLAPENRLPAAYDDCYSSLEWLSHQASCEPWLEQANLSRVFLSSDSAGGKIAHQTALRAVQSQINRVSIKGLMLIHLYFGSQNRTNLAKSNLESFDVTMSDL
>Lj8C715T5.1
MPIVAEAPDYIRVFSDGSVKRFDHQTAPPSNVSINGFKSKDLTIDHSKPITARIYLPDTPKPDNRLPVLVYFHGGGFCVGSTTWLGYHHFLGGLSFESQSIVLSIDYRLAPENRLPAAYDDCYSSLEWLSHHANSEPWLERADLSHVFLSGDSAGGNIAHQTTLRAVRSQVNLVSIKGLMPIHPYFGSQNRTNLEKSNLDSFDVTMNDLFWNLSLPEGSNRDYFGCNFEKEVVTVEEWQRFPAVVVYVAELDFLKERGVMYFQFLKKNWVKDVKLVEAEGETHVYHVYRPLSEAAKVLQKQMSEFIHSI
>Lj8A102T61.1
MFHKILVLFQSLLIFLSLTSAASNNNSINDPQFLCNNTPVPPSTDPQTGIQYKDVKISPTVTGRLYIPKYLTPFRDLPVIIYFHGGGPFCSGSAFSLPYNNFSLSLSNHTDSIILSVEYRPAPVNPITTGYEDSWAAIKWVAGHANGTVDEPWLEDFADFKRVFLAGDGAGANIAHNMAMQVGWGNFSGVDLVGLVLIHPLLWGEKPVSSSGRGLVSMMWRFVCPASSGLADPRVNPAMDPNLGRMGCEKVMVFVAGLDPVVKGNYGYVEALRESGWKGDVVSVETTRKKNGFYLDPNYTKSDEAEMMLKLAGSFIN
>Lj9P640T43.1
MGIRVGLDPDGVGLKLVGIVLVHPFFGGGFSDKLWAFVKPGTCGSDDPEFNPGKDPKLKDMGCERVLVCVGGKDFLKDRGWYYGEVVGKSGWGGKVEVVEDKEEDHVFHLMKPTSENAAAMMNRVVAFINET
>Lj9A358T48.1
YPRLPTLLSSTQIRPHLSIPPHPTILPNLRPPPIPRPIQRRPYLPRIRPLRPPLPPPNHKNSLLIHIHGGAFCLGSPTNPTFHNYLVSLVSKSAVIAISIDYRALTLICALYKIAVFNYRLAPEHPLPTAYEDSWTALQWIASHADKSGPDPWLNDHADFERVYLSGESAGANIANDVVLRAWVEELGHGFKIWGLVLIQPYFGGKEVDKMYKFMCPTSSGSDDDPRLNPAVDPRLERIGCSRVLVVVAEKDWLRERGKGYYELLKKKGLGGEVGFMEVEGMGHGFHLLDPTCEKALTQLDRVASFLKKE
MATTSTEATPYEVDECRGVLRVYSDGSIVRSAKPSFDFPVHDDGSVLWKDVVFDPINNLQLRLYKPAAATTKLPIFYYIHGGGFCIGSRTWPNFQSYCFQLALELQAVVVAPDYRLAPENRLPAAIEDGFMAMKWLQGQAEMKEGMSGLLRWLTLRSTTTNVANFVKCLYLILLFSYDELCRYWRLSIPLGETTDHPLINPFGPASPSLENVDLDPILVVVGGSDLLKDRVEDYAKRLEAWGKKIEYVEFKGQQHGFVTINPHTLPADELMLIIKRFITQYST
>Lj2A833T32.1
MATTSTEATPYEVDECRGVLRVYSDGSIVRSTKPSFNVPVHDDGSVLWKDTVFDPINNLQLRLYKPAAATTKLPIFYYIHGGGFCIGSRTWPNCQNYCFQLALKLQAVVVAPDYRLAPENRLPAAIEDGFVAMKWLQGQAEMEENDKWLTEVADFGRVFVSGDSAGGNIAHHLAVQLGPGSVQLGPVRVKGFWTLSIPLGETTDHPLINPFGPVSPSLENVNFDPILVVVGGSDLLKDRAKDYAKKLKVWGKEDRVC
>Lj3C1018T4.1
MGITTLDPSLSYQITKVPQQHNGVVIEEIDGLIRVYKDGHVERPQIVPCVTSALAPEFNVTSRDIVIDKYTNIWARFYVPKCQSKLPLLVYFHGGGFCVGSATWSCYHNFLARLSAIARCIIMSVNYRLAPEHPLPAAYDDGFKALVWLKQQAISGPSEGF
>Lj3C740T7.1
MASSNNEIVTDFFPVLRIFKNGTVERIFGSPYVPPSPKDPTTGVSSKDISISPEISARIYLPPGASSKLPVLVYFHSGAFCVESAFSAAHHAYLNAIVSESRAVAISVEYRSAPEHPLPAAYEDCWTAIQWVGSHSTTTPHTTISVLEPWITNFGDFNRIYIGGDSAGGNIVHNILLRAGNDQLCGNMKIKGAFLSHPYFWGSEPLKGESGEESLAHKLWMFVNPSAAGGIDDPAINPFVGPSLKGLRCSRLLVCVSEKDELRERGVKYCEVVRESGWEGEVELVQVEGEDHCFHIFRADCDKARNLIKKLASFIV
>Lj3C740T6.1
MLFVLLFYSINFGRLEPWITNFGDFNRIYIGGDSAGGNIVHNILLRAGNDQLCGNIKIKGAFLSHPYFWGSEPLKGESGKESLAHKLWMFVNPSAAGGIDDPAINPFTGPSLKGLRCSRLLVCVSEKDELRERGVKYCEVVRESGWEGEVELVQVEGEDHCFNIFRADCDKARNLTKKLASFIV
>Lj3C740T5.1
MASSNNEIVTDFFPILRIYKDGTVERIFGSPYVPPSPKDPTTGVSSKDISISPEISARLYLPPAASSKLPVLVYFHGGAFCVESAFSAAHHAYLNAIVSESRAIAISVEYRSAPEHPLPAAY
>Lj4A53T54.1
MDSSKSEIAHDVPPYLTVYKDGTIQRHFGEEIAPASLDAATGTLSKDLLIVPETGVHARLYRPNISTDQRLPLVVYFHGGAFCISSAFDPKYHHSLNKLVAESNIVIVSVNYRLAPEHPLPAAFQDSWAALHWVASHASGGGSEAWLSAVDFSKVFLAGDSAGATISHHMAMRVADPDHNIGLKVHGILMIHPYFWGKEPIGSEVTDTARKAMVDTWWEFVCPSDKGHDDPLINPFADGAPDVTGLGCERIIVCVAEMDILRDRGRDYYERVVKSGWKGVAEMVEVEGEDHVFHILNPDGEKAVNMIKRLATFINQ
>Lj5A207T80.1
MASIIPELAYELPPFFKVYKDGKIERLMGTDIIPPGTDPETGVQSKDIVISPETGVSARLYKPKQTNQNQKVPLIIYFHGGGFYVQTPFSSTYQPFLNSLVAESNIIIVSVDYRKAPEHPLPIGYDDCWASIKWVASHSNCGGPEEWINEYANLECTFIMGDSAGANIAHNMAVRVGLDKPSGATIQGLILMHPYFWGKDPVGSESGDVETRSIIENYWKLACPRNSSADDPLMNPKMDPNLARLGCGRVLVFAAEIDFLRCRAWFYHETLMKSGWGGSAEIMESEGEEHVFHLYRPHCEKAIVLRKRVVSFINNTEKTISS
>Lj5A207T79.1
MDSEVTHDYHPFFRVYKDGHIERFIGTPFVPASDDSTVAVRSKDVVISNEPKVSARIFLPKTVTPNQKLPLLVYVHGGAFSIESAFSSLYYHYLTSLVADSNVVVVSVEYRLAPEHPIPACYDDTWTAMEWTARHSNGQGPDLWLNEHADFNRVFVAGDSAGANISHNVMVKYSNEGLGSVKILGMVLVHPYFGNKKPAKLWEYICPDSTGLDDLRLNPAAHPGLLAKLGKIRVLICTAENDHLRDRGWDYYEGLKKSGWGGEVEIVETEGEDHVFHLFNPKCEKAGVLMKLVTSFLNENKVDGSIGIMNTPVGSSLNQSNASSLL
>Lj6A597T90.1
MASTPTKEIATEILPAIRVYKDGTVERLLGSPFAPPSPQDPTTNVSSKDITISPQFSARLYLPKLTTAHKQKSLPILVYFHGGGFCIESAFSVAHHAYINSLVGESRAIAVSVEYRRVPEHLLPAAYEDCWNALQWVASHSVVNQNLEPEPWIVDFGDFNRVYIGGANIVHNIALRAGTEPINNDVKIKGAFLAHPYFSGSKQLAKETHNPNDENSLGYKLWTLAYPTAPGGIDNPMINPFGANAPSLRGLGCSRLLVCVAEKDGLRERGVGYYEGVKESGWNGEIELFEGLGEEHCYHVLKPGTLSTRDLIKRLASFIVV
>Lj6A597T89.1
MASNKKEVATELLPVLRVYKDGTVDRLYPDPQAPPSPLDPATGVSSKDIMISPEANVVAVSVGYRLAPEHPLPAAYEDCWTGLQWVASHADHDTIILDKEENKVEPEPWLINHGDFDRVYLGGDSAGGSEPMENHKESLLYRFWMLAYPNAPGGIDNPMINPWAPGGPDLSRIGCGRLFVCIGEKDKLRERGFRYCEAVRESGWKGELEFVEVEGEDHIFHIFKPHSDKAKSLIKRMASFIV
>Lj8C695T12.1
MPIIAEAPDYIRVFSDGSVKRFDHLTAPPSNVSINGFKSKDLTIDHSKPITARIYLPDTPKPDNRLPVLVYFHGGGFCVGSTTWLGYHHFLGGLSFESQSIVLSIDYRLAPENRLPAAYDDCYSSLEWLSHHANSEPWLERADLSHVFLSGDSAGGNIAHQTTLRAVRSQVNLVSIKGLMPIHPYFGSQNRTNLEKSNLDSFDVTMNDLFWNLSLPEGSNRDYFGCNFEKEVVTVEEWQRFPAVVVYVAELDFLKERGVMYFQFLKKNWVKDVKLVEAEGETHVYHVYRPLSEAAKVLQKQMSEFIHSI
>Lj8C102T3.1
MTFKTHKLFPSLFILISLTSNSIAHNQTNSDNQFLCSNGKQNPRTAPPPFLWTPALVQTKDIQIQPATGLSGRLYLPKFGAIPFTDLPLIIYFHGGGAFCSGSAYSLPYHKFSLRLAARSMSIILSVQYRSAPAHSIRVGYDDSWTALKWVASHSNSGRGLAPGHDPWIKHHTNFNRVFLAGDGVGANIAHTMGIRVGLENLGGVNISGVILIHPLLWGEKVKLDNEWGERRKVIYGVKDSAREWVSHLWSFVCPSSSGLGDPSVNPALDPDLRRMGCKRVVVFVAGDDPVAKGNYGYVAALRRSGWKGVVEIVKSKGKKNGFYLDPKYDISTEAINLMKKVVSFISHSRKAYNGTV
>Lj8P715T22.1
NARIFLPDTPKPNNHLPILVYFHGGGFCVGSTISLGYHHFLGALPVESQSIVPSIDYWLAPENRLPAAYDDCYSSLEWLSHQASCEPWLEQANLSRVFLSSDSAGGKIAHQTALRAVQSQVNCVSIKGLMLIHLYFGSQNRTNLEKSNPESFDVTMSDL
>Lj8P695T59.1
NARIFLPDTPKPNNHLPILVYFHGGGFCVGSTISLGYHHFLGALPVESQSIVPSIDYRLAPENRLPAAYDDCYSSLEWLSHQASCEPWLEQANLSRVFLSSDSAGGKIAHQTALRAVQSQINRVSIKGLMLIHLYFGSQNRTNLAKSNLESFDVTMSDL
>Lj8C715T5.1
MPIVAEAPDYIRVFSDGSVKRFDHQTAPPSNVSINGFKSKDLTIDHSKPITARIYLPDTPKPDNRLPVLVYFHGGGFCVGSTTWLGYHHFLGGLSFESQSIVLSIDYRLAPENRLPAAYDDCYSSLEWLSHHANSEPWLERADLSHVFLSGDSAGGNIAHQTTLRAVRSQVNLVSIKGLMPIHPYFGSQNRTNLEKSNLDSFDVTMNDLFWNLSLPEGSNRDYFGCNFEKEVVTVEEWQRFPAVVVYVAELDFLKERGVMYFQFLKKNWVKDVKLVEAEGETHVYHVYRPLSEAAKVLQKQMSEFIHSI
>Lj8A102T61.1
MFHKILVLFQSLLIFLSLTSAASNNNSINDPQFLCNNTPVPPSTDPQTGIQYKDVKISPTVTGRLYIPKYLTPFRDLPVIIYFHGGGPFCSGSAFSLPYNNFSLSLSNHTDSIILSVEYRPAPVNPITTGYEDSWAAIKWVAGHANGTVDEPWLEDFADFKRVFLAGDGAGANIAHNMAMQVGWGNFSGVDLVGLVLIHPLLWGEKPVSSSGRGLVSMMWRFVCPASSGLADPRVNPAMDPNLGRMGCEKVMVFVAGLDPVVKGNYGYVEALRESGWKGDVVSVETTRKKNGFYLDPNYTKSDEAEMMLKLAGSFIN
>Lj9P640T43.1
MGIRVGLDPDGVGLKLVGIVLVHPFFGGGFSDKLWAFVKPGTCGSDDPEFNPGKDPKLKDMGCERVLVCVGGKDFLKDRGWYYGEVVGKSGWGGKVEVVEDKEEDHVFHLMKPTSENAAAMMNRVVAFINET
>Lj9A358T48.1
YPRLPTLLSSTQIRPHLSIPPHPTILPNLRPPPIPRPIQRRPYLPRIRPLRPPLPPPNHKNSLLIHIHGGAFCLGSPTNPTFHNYLVSLVSKSAVIAISIDYRALTLICALYKIAVFNYRLAPEHPLPTAYEDSWTALQWIASHADKSGPDPWLNDHADFERVYLSGESAGANIANDVVLRAWVEELGHGFKIWGLVLIQPYFGGKEVDKMYKFMCPTSSGSDDDPRLNPAVDPRLERIGCSRVLVVVAEKDWLRERGKGYYELLKKKGLGGEVGFMEVEGMGHGFHLLDPTCEKALTQLDRVASFLKKE
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University